UA63993C2 - Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул - Google Patents

Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул

Info

Publication number
UA63993C2
UA63993C2 UA2000105783A UA2000105783A UA63993C2 UA 63993 C2 UA63993 C2 UA 63993C2 UA 2000105783 A UA2000105783 A UA 2000105783A UA 2000105783 A UA2000105783 A UA 2000105783A UA 63993 C2 UA63993 C2 UA 63993C2
Authority
UA
Ukraine
Prior art keywords
dosage forms
flash
oral dosage
granules
variants
Prior art date
Application number
UA2000105783A
Other languages
English (en)
Russian (ru)
Inventor
Х. Котарі Санджеєв
С. Десаі Дів'якант
Original Assignee
Брістол-Майерс Сквібб Компані
Бристол-Майерс Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24186805&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA63993(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Брістол-Майерс Сквібб Компані, Бристол-Майерс Сквибб Компани filed Critical Брістол-Майерс Сквібб Компані
Publication of UA63993C2 publication Critical patent/UA63993C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Заявляються гранули для одержання фармацевтичних лікарських форм, що швидко тануть, для перорального прийому. Окрім принаймні однієї лікарської речовини, гранули містять комбінацію ексципієнтів, що складається із супердезінтегранту, диспергатора, розподілювача і зв’язувальної речовини, і можуть також включати у себе інші звичайні інгредієнти, наприклад, підсолоджувачі й ароматизатори. Запропоновані гранули є стійкими, а їх приготування не потребує розчинників і особливих технологічних умов. Лікарські форми, зокрема таблетки, отримані з таких гранул на звичайному устаткуванні, розпадаються в роті менше, ніж за двадцять п'ять секунд.
UA2000105783A 2000-04-12 2000-10-12 Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул UA63993C2 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54794800A 2000-04-12 2000-04-12

Publications (1)

Publication Number Publication Date
UA63993C2 true UA63993C2 (uk) 2004-02-16

Family

ID=24186805

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2000105783A UA63993C2 (uk) 2000-04-12 2000-10-12 Фармацевтична лікарська форма, що швидко тане в роті (варіанти) та спосіб формування гранул

Country Status (43)

Country Link
US (3) US20100016448A1 (uk)
EP (2) EP1566174A3 (uk)
JP (1) JP3773763B2 (uk)
KR (1) KR100477293B1 (uk)
CN (1) CN100353933C (uk)
AR (1) AR024384A1 (uk)
AT (1) ATE328584T1 (uk)
AU (1) AU752214B2 (uk)
BG (1) BG65007B1 (uk)
BR (1) BR0003158A (uk)
CA (1) CA2311734C (uk)
CO (1) CO5190672A1 (uk)
CY (1) CY1105170T1 (uk)
CZ (1) CZ299145B6 (uk)
DE (1) DE60028536T2 (uk)
DK (1) DK1145711T3 (uk)
EE (1) EE04331B1 (uk)
EG (1) EG23943A (uk)
ES (1) ES2265836T3 (uk)
GE (1) GEP20022851B (uk)
HK (1) HK1039572B (uk)
HU (1) HU228864B1 (uk)
ID (1) ID29837A (uk)
IL (1) IL136901A (uk)
IN (1) IN188856B (uk)
LT (1) LT4896B (uk)
LV (1) LV12731B (uk)
MY (1) MY125766A (uk)
NO (1) NO330270B1 (uk)
NZ (1) NZ505302A (uk)
PE (1) PE20010298A1 (uk)
PL (1) PL200409B1 (uk)
PT (1) PT1145711E (uk)
RO (1) RO118563B1 (uk)
RU (1) RU2201216C2 (uk)
SG (2) SG108230A1 (uk)
SI (1) SI20511B (uk)
SK (1) SK286368B6 (uk)
TR (1) TR200001810A2 (uk)
TW (1) TWI262799B (uk)
UA (1) UA63993C2 (uk)
UY (1) UY26306A1 (uk)
ZA (1) ZA200003121B (uk)

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