UA118653C2 - Суперагоністи глікопротеїнового гормону тривалої дії - Google Patents
Суперагоністи глікопротеїнового гормону тривалої діїInfo
- Publication number
- UA118653C2 UA118653C2 UAA201500722A UAA201500722A UA118653C2 UA 118653 C2 UA118653 C2 UA 118653C2 UA A201500722 A UAA201500722 A UA A201500722A UA A201500722 A UAA201500722 A UA A201500722A UA 118653 C2 UA118653 C2 UA 118653C2
- Authority
- UA
- Ukraine
- Prior art keywords
- glycoprotein hormone
- superagonists
- acting
- long
- hormone long
- Prior art date
Links
- 229940088597 hormone Drugs 0.000 title abstract 3
- 239000005556 hormone Substances 0.000 title abstract 3
- 102000003886 Glycoproteins Human genes 0.000 title abstract 2
- 108090000288 Glycoproteins Proteins 0.000 title abstract 2
- 230000002483 superagonistic effect Effects 0.000 title 1
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Винахід стосується модифікованого поліпептиду бичачої альфа-субодиниці та модифікованого гліпротеїнового гормону, що містить дану альфа-субодиницю. Винахід також стосується способу стимуляції овуляції у тварин, який включає введення вказаного глікопротеїнового гормону.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261677331P | 2012-07-30 | 2012-07-30 | |
PCT/US2013/052510 WO2014022283A2 (en) | 2012-07-30 | 2013-07-29 | Glycoprotein hormone long-acting superagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
UA118653C2 true UA118653C2 (uk) | 2019-02-25 |
Family
ID=49995487
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA201500722A UA118653C2 (uk) | 2012-07-30 | 2013-07-29 | Суперагоністи глікопротеїнового гормону тривалої дії |
Country Status (21)
Country | Link |
---|---|
US (5) | US9187545B2 (uk) |
EP (4) | EP4012033A1 (uk) |
JP (1) | JP6429774B2 (uk) |
CN (3) | CN112409472A (uk) |
AR (1) | AR091936A1 (uk) |
AU (2) | AU2013296709B2 (uk) |
BR (1) | BR112015001885B1 (uk) |
CA (2) | CA3108181A1 (uk) |
DK (2) | DK3572515T3 (uk) |
ES (2) | ES2894135T3 (uk) |
HR (1) | HRP20190847T1 (uk) |
HU (1) | HUE044016T2 (uk) |
MX (1) | MX360717B (uk) |
NZ (1) | NZ707016A (uk) |
PL (2) | PL3572515T3 (uk) |
PT (2) | PT2880164T (uk) |
RS (1) | RS58881B1 (uk) |
RU (2) | RU2018132561A (uk) |
UA (1) | UA118653C2 (uk) |
WO (1) | WO2014022283A2 (uk) |
ZA (1) | ZA201502778B (uk) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112409472A (zh) | 2012-07-30 | 2021-02-26 | 特洛佛根股份有限公司 | 糖蛋白激素长效超激动剂 |
US10457713B2 (en) | 2012-07-30 | 2019-10-29 | Trophogen, Inc. | Glycoprotein hormone long-acting superagonists |
WO2015069777A1 (en) | 2013-11-05 | 2015-05-14 | Trophogen Inc. | Glycoprotein hormone long-acting superagonists |
BR102015032660B1 (pt) | 2015-12-28 | 2019-05-28 | Ouro Fino Saúde Animal Participações S.A. | PROCESSO DE PRODUÇÃO DE UMA GONADOTROFINA CORIÔNICA EQUINA RECOMBINANTE (reCG): COMPOSIÇÃO VETERINÁRIA E USO |
Family Cites Families (46)
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US4196123A (en) | 1978-11-20 | 1980-04-01 | Eugenia Rosemberg | Hybrid chorionic gonadotropin preparations and methods for stimulating ovulation using same |
ATE65407T1 (de) | 1984-04-03 | 1991-08-15 | Serono Lab | Verfahren zur herbeifuehrung der ovulation. |
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US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
DE3751602T2 (de) | 1987-05-12 | 1996-05-02 | Serono Pharm Praep | Subkutane Verabreichung des humanen Choriongonadotropins. |
US5017566A (en) | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
US6018026A (en) | 1988-01-22 | 2000-01-25 | Zymogenetics, Inc. | Biologically active dimerized and multimerized polypeptide fusions |
WO1990002812A1 (en) | 1988-09-01 | 1990-03-22 | Applied Research Systems Ars Holding N.V. | Methods for producing gonadotropin and tsh super-agonists |
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EP0555229B1 (en) | 1990-07-31 | 1996-06-05 | The Liposome Company, Inc. | Accumulation of amino acids and peptides into liposomes |
US5612034A (en) | 1990-10-03 | 1997-03-18 | Redcell, Inc. | Super-globuling for in vivo extended lifetimes |
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US5604198A (en) | 1994-05-12 | 1997-02-18 | Poduslo; Joseph F. | Method to enhance permeability of the blood/brain blood/nerve barriers to therapeutic agents |
RU2213099C2 (ru) * | 1994-08-12 | 2003-09-27 | Вашингтон Юниверсити | Одноцепочечный белок, модулятор гормонов лютеинизирующего, фолликулостимулирующего, тиреостимулирующего и хорионического гонадотропина (варианты), молекула нуклеиновой кислоты (варианты), вектор (варианты), линия трансформированных клеток сно (варианты), способ продуцирования одноцепочечного белка (варианты) |
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CN112409472A (zh) | 2012-07-30 | 2021-02-26 | 特洛佛根股份有限公司 | 糖蛋白激素长效超激动剂 |
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2013
- 2013-07-29 CN CN202011090733.0A patent/CN112409472A/zh active Pending
- 2013-07-29 UA UAA201500722A patent/UA118653C2/uk unknown
- 2013-07-29 EP EP21186472.3A patent/EP4012033A1/en active Pending
- 2013-07-29 EP EP13826476.7A patent/EP2880164B1/en active Active
- 2013-07-29 PL PL19170014T patent/PL3572515T3/pl unknown
- 2013-07-29 CN CN201380047511.2A patent/CN104619846B/zh active Active
- 2013-07-29 PL PL13826476T patent/PL2880164T3/pl unknown
- 2013-07-29 EP EP19170014.5A patent/EP3572515B1/en active Active
- 2013-07-29 RU RU2018132561A patent/RU2018132561A/ru not_active Application Discontinuation
- 2013-07-29 EP EP19166115.6A patent/EP3533874A1/en not_active Withdrawn
- 2013-07-29 ES ES19170014T patent/ES2894135T3/es active Active
- 2013-07-29 AU AU2013296709A patent/AU2013296709B2/en active Active
- 2013-07-29 CA CA3108181A patent/CA3108181A1/en active Pending
- 2013-07-29 ES ES13826476T patent/ES2727659T3/es active Active
- 2013-07-29 HU HUE13826476A patent/HUE044016T2/hu unknown
- 2013-07-29 DK DK19170014.5T patent/DK3572515T3/da active
- 2013-07-29 MX MX2015001414A patent/MX360717B/es active IP Right Grant
- 2013-07-29 CA CA2880520A patent/CA2880520C/en active Active
- 2013-07-29 DK DK13826476.7T patent/DK2880164T3/da active
- 2013-07-29 NZ NZ707016A patent/NZ707016A/en active IP Right Revival
- 2013-07-29 PT PT13826476T patent/PT2880164T/pt unknown
- 2013-07-29 WO PCT/US2013/052510 patent/WO2014022283A2/en active Application Filing
- 2013-07-29 JP JP2015525484A patent/JP6429774B2/ja active Active
- 2013-07-29 CN CN202011095353.6A patent/CN112458096A/zh active Pending
- 2013-07-29 RU RU2015103059A patent/RU2668174C2/ru active
- 2013-07-29 RS RS20190625A patent/RS58881B1/sr unknown
- 2013-07-29 BR BR112015001885-8A patent/BR112015001885B1/pt active IP Right Grant
- 2013-07-29 PT PT19170014T patent/PT3572515T/pt unknown
- 2013-07-30 US US13/954,690 patent/US9187545B2/en active Active
- 2013-07-30 AR ARP130102702A patent/AR091936A1/es unknown
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2014
- 2014-06-19 US US14/309,317 patent/US9249205B2/en active Active
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2015
- 2015-04-23 ZA ZA2015/02778A patent/ZA201502778B/en unknown
- 2015-08-20 US US14/831,124 patent/US10766941B2/en active Active
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2018
- 2018-05-31 AU AU2018203815A patent/AU2018203815B2/en active Active
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2019
- 2019-05-07 HR HRP20190847TT patent/HRP20190847T1/hr unknown
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2020
- 2020-09-04 US US17/012,387 patent/US20210054041A1/en active Pending
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2023
- 2023-04-05 US US18/296,005 patent/US20230357345A1/en active Pending
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