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Priority claimed from PCT/US2007/085100external-prioritypatent/WO2008064157A1/en
Publication of UA113716C2publicationCriticalpatent/UA113716C2/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
Даний винахід стосується імідазо[1,2-b][1,2,4]триазинів і імідазо[1,2-а]піримідинів і їх фармацевтичних композицій, які є інгібіторами кіназ, таких як c-Met, і можуть бути використані в лікуванні раку і інших захворювань, пов'язаних з дизрегуляцією кіназних шляхів.The present invention relates to imidazo [1,2-b] [1,2,4] triazines and imidazo [1,2-a] pyrimidines and their pharmaceutical compositions, which are kinase inhibitors, such as c-Met, and can be used in treatment of cancer and other diseases associated with dysregulation of kinase pathways.
UAA200906353A2006-11-222007-11-19
IMIDASOTRIAZINES AND IMIDASOPIRIMIDINS AS KINASE INHIBITORS
UA113716C2
(en)
Compounds derived from imidazo [1,2-a] pyrazine; pharmaceutical composition; and use of the compounds as protein kinase inhibitors in the treatment of cancer.
COMPOUNDS DERIVED FROM PIRIMIDO [5,4-D] PIRIMIDINA-2,4,6,8-TETRAONA; PHARMACEUTICAL COMPOSITION; AND USE IN THE TREATMENT OF SUCH DISEASES AS METABOLIC DISORDER, DYSLIPIDEMIA AND CANCER.
Compounds derived from pyrimidine, tyrosine kinase inhibitors; pharmaceutical compositions comprising them; and its use in the treatment and / or prevention of cancer, inflammatory diseases and autoimmune diseases.
Compounds derived from pyrimido [5,4-d] pyrimidine, which act as tyrosine kinase inhibitors; and pharmaceutical compositions that comprise them, useful in the treatment of diseases characterized by excessive or abnormal cell proliferation
Compounds derived from imidazo [1,2-a] pyridine; preparation procedure; pharmaceutical composition; intermediate compounds; and use in the treatment of cancer.
DERIVATIVES 1,2,3,4-TETRAGIDROPYRROLO [1,2-A] PIRAZIN-6-CARBOXAMIDES AND 2,3,4,5-TETRAHYDROPYRROLO [1,2-a] [1,4] -DIAZEPIN-7-CARBOXAMIDES , THEIR RECEIVING AND THEIR APPLICATION IN THERAPY