TWI772274B - Water-dispersible titanium dioxide composite powder and oil-in-water type cosmetic composition comprising the same - Google Patents
Water-dispersible titanium dioxide composite powder and oil-in-water type cosmetic composition comprising the same Download PDFInfo
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Abstract
Description
以下發明是有關於一種具有膚色改善功效及優異的皮膚穩定性的水分散二氧化鈦複合粉末以及包含其的水包油（oil-in-water）型化妝品組成物。The following invention relates to a water-dispersed titanium dioxide composite powder having a skin tone improving effect and excellent skin stability, and an oil-in-water cosmetic composition comprising the same.
藉由以下方式來製備通常應用於傳統化妝品領域中的油包水（water-in-oil，W/O）型化妝品組成物：將用於顏料的二氧化鈦（TiO2 ）分散於作為連續相的外部油相中以使得具有作為即時膚色改善效果的白色面容（white cast）；以及使用具有低親水親油均衡值（low hydrophile-lipophile balance，HLB）的界面活性劑來穩定乳液配方。在此種情形中，用於顏料的二氧化鈦包含於作為連續相的外部油相中以獲得優異的配方穩定性及皮膚穩定性。A water-in-oil (W/O) type cosmetic composition commonly used in the conventional cosmetic field is prepared by dispersing titanium dioxide (TiO 2 ) for a pigment in the outer portion as a continuous phase in the oil phase so as to have a white cast as an immediate skin tone improvement effect; and use a surfactant with a low hydrophile-lipophile balance (HLB) to stabilize the emulsion formulation. In this case, titanium dioxide for the pigment is contained in the external oil phase as the continuous phase to obtain excellent formulation stability and skin stability.
然而，所述油包水型配方雖具有優異的耐水性以使得其具有優異的化妝品持續性，但其具有例如黏性及油膩感等皮膚負擔以及不良的覆蓋性及塗敷性。However, the water-in-oil type formulation has excellent water resistance so that it has excellent cosmetic persistence, but it has skin burdens such as stickiness and greasy feeling, and poor coverage and spreadability.
因此，若將所述配方改為水包油型，則可實現亮白、滋潤及柔軟的感覺以及高保濕感，但使用用於顏料的二氧化鈦來達成膚色改善效果導致破壞乳液介面中的配方穩定性以及造成皮膚刺激的問題。Therefore, if the formulation is changed to an oil-in-water type, a brightening, moisturizing and soft feel and a high moisturizing feel can be achieved, but the use of titanium dioxide for pigments to achieve a complexion-improving effect results in destabilizing the formulation in the emulsion interface Sexuality and problems that cause skin irritation.
因此，目前一直需要開發一種在減少皮膚刺激的同時具有維持膚色改善效果、優異的感覺以及高保濕感的化妝品組成物。Therefore, there has been a need to develop a cosmetic composition that has a skin tone improvement effect, an excellent feeling, and a high moisturizing feeling while reducing skin irritation.
作為用於皮膚刺激改善的類似先前技術文獻，已提議韓國專利公開案第10-2012-0043167號。As a similar prior art document for skin irritation improvement, Korean Patent Publication No. 10-2012-0043167 has been proposed.
[先前技術文獻][Prior Art Literature]
[專利文獻][Patent Literature]
韓國專利公開案第10-2012-0043167號（2012年5月3日）Korean Patent Publication No. 10-2012-0043167 (May 3, 2012)
本發明的實施例是有關於提供一種具有膚色改善功效及優異的皮膚穩定性的水分散二氧化鈦複合粉末以及包含其的水包油型化妝品組成物。Embodiments of the present invention are directed to providing a water-dispersed titanium dioxide composite powder having a skin tone improving effect and excellent skin stability, and an oil-in-water cosmetic composition comprising the same.
在一個一般態樣中，一種水分散二氧化鈦組成粉末是藉由以研磨製程將包含以下的混合物粉碎來製備：經烷氧基矽烷（alkoxysilane）進行疏水性表面處理的二氧化鈦；具有12至18的親水親油均衡值的非離子界面活性劑；以及具有1至5的親水親油均衡值的脂質。In a general aspect, a water-dispersed titanium dioxide composition powder is prepared by pulverizing a mixture comprising the following in a grinding process: titanium dioxide hydrophobic surface-treated with alkoxysilane; hydrophilic A nonionic surfactant having a lipophilic balance; and a lipid having a hydrophilic-lipophilic balance of 1 to 5.
在另一一般態樣中，一種水包油型化妝品組成物包含所述水分散二氧化鈦複合粉末。In another general aspect, an oil-in-water cosmetic composition comprises the water-dispersed titanium dioxide composite powder.
藉由以下詳細說明、圖式、及申請專利範圍，其他特徵及態樣將顯而易見。Other features and aspects will be apparent from the following detailed description, drawings, and claims.
以下，將參照附圖來詳細闡述根據本發明的二氧化鈦複合粉末。以實例方式來提供欲在下文提供的圖式，以使得本發明的觀念可充分地傳達至熟習本發明所屬技術者。因此，本發明並不僅限於下文所提供的圖式，而是可被修改成諸多不同形式。此外，下文所提出的圖式將被誇大以使本發明的精神及範圍變清晰。此外，在說明書通篇中，相同圖示編號指示相同元素。Hereinafter, the titanium dioxide composite powder according to the present invention will be explained in detail with reference to the accompanying drawings. The drawings to be provided hereinafter are provided by way of example so that the concepts of the present invention may be fully conveyed to those skilled in the art to which the present invention pertains. Therefore, the present invention is not limited to the drawings provided below, but can be modified into many different forms. Furthermore, the drawings presented below will be exaggerated in order to clarify the spirit and scope of the present invention. Furthermore, the same reference numerals refer to the same elements throughout the specification.
除非另外定義，否則本文所用的技術用語及科學用語具有熟習本發明所屬技術者所理解的一般意義，且將在以下說明及附圖中省略對於使本發明模糊的已知功能及構型的說明。Unless otherwise defined, technical and scientific terms used herein have the ordinary meaning as understood by those skilled in the art to which the present invention belongs, and descriptions of known functions and configurations that would obscure the present invention will be omitted in the following description and drawings. .
本發明是有關於一種水分散二氧化鈦複合粉末，所述水分散二氧化鈦複合粉末藉由使經疏水性表面處理的二氧化鈦與具有不同親水親油均衡值（HLB）的界面活性劑及脂質一起經受研磨而成為水分散的，且因此可在應用於水包油型化妝品組成物時保證配方穩定性，並減少皮膚刺激。The present invention relates to a water-dispersed titania composite powder prepared by subjecting hydrophobic surface-treated titania together with surfactants and lipids having different hydrophilic-lipophilic balances (HLBs). It becomes water-dispersible and thus can ensure formulation stability and reduce skin irritation when applied to oil-in-water cosmetic compositions.
具體而言，根據本發明的示例性實施例的水分散二氧化鈦複合粉末可藉由以研磨製程將包含以下的混合物粉碎來製備：經烷氧基矽烷進行疏水性表面處理的二氧化鈦；具有12至18的親水親油均衡值的非離子界面活性劑；以及具有1至5的親水親油均衡值的脂質。Specifically, the water-dispersed titanium dioxide composite powder according to the exemplary embodiment of the present invention can be prepared by pulverizing a mixture including the following in a grinding process: titanium dioxide hydrophobic surface-treated with alkoxysilane; having 12 to 18 A nonionic surfactant with a hydrophilic-lipophilic balance of 1 to 5; and a lipid with a hydrophilic-lipophilic balance of 1 to 5.
如此一來，藉由使用經烷氧基矽烷進行疏水性表面處理的二氧化鈦來維持白色面容作為皮膚膚色改善效果，且此外，可藉由使二氧化鈦經受研磨製程而進行水分散，以使得無論是否使用相同含量的二氧化鈦均可顯著減少皮膚刺激，且即使在分散於水包油型配方的情形中，二氧化鈦亦可藉由在研磨製程中使用二氧化鈦、具有12至18的親水親油均衡值的非離子界面活性劑以及具有1至5的親水親油均衡值的脂質的混合物來穩定地維持所述配方。As such, the white face is maintained as a skin tone improving effect by using titanium dioxide hydrophobic surface-treated with alkoxysilane, and furthermore, water dispersion can be performed by subjecting titanium dioxide to a grinding process so that whether or not it is used The same content of titanium dioxide can significantly reduce skin irritation, and even in the case of dispersion in oil-in-water formulations, titanium dioxide can be obtained by using titanium dioxide in the grinding process, non-ionic with a hydrophilic-lipophilic balance of 12 to 18 A mixture of surfactants and lipids with a hydrophilic-lipophilic balance of 1 to 5 to stably maintain the formulation.
在本發明的示例性實施例中，以水分散二氧化鈦複合粉末的總重量計，所述粉末可包含40重量%至50重量%的二氧化鈦、1重量%至10重量%的非離子界面活性劑、以及30重量%至40重量%的脂質。在此範圍內，所述複合粉末可在研磨處理中具有優異的水分散效能，且因此可在製備水包油型化妝品組成物時保證優異的配方穩定性及皮膚安全性。In an exemplary embodiment of the present invention, based on the total weight of the water-dispersed titanium dioxide composite powder, the powder may include 40% to 50% by weight of titanium dioxide, 1% to 10% by weight of a nonionic surfactant, and 30% to 40% by weight of lipids. Within this range, the composite powder may have excellent water dispersibility in grinding treatment, and thus may ensure excellent formulation stability and skin safety when preparing an oil-in-water cosmetic composition.
在本發明的示例性實施例中，使用二氧化鈦來達成即時皮膚膚色改善效果，且塗佈於二氧化鈦的表面上的烷氧基矽烷可用於藉由與界面活性劑的疏水基發生疏水相互作用而有助於二氧化鈦穩定地存在於水包油配方中的油與水的介面上。具體而言，烷氧基矽烷可滿足以下化學式1：
其中，R1為C1至C3烷基；R2為C1至C18烷基、烯基、或炔基；R3為-H或C1至C3烷基；且n為1至3的實數。 wherein R 1 is a C1 to C3 alkyl group; R 2 is a C1 to C18 alkyl, alkenyl, or alkynyl group; R 3 is -H or a C1 to C3 alkyl group; and n is a real number from 1 to 3.
更具體而言，作為非限制性具體實例，其可選自由以下組成的群組的任一者或者二或更多者：乙烯基三甲氧基矽烷、乙烯基三乙氧基矽烷、2-(3,4-環氧環己基)乙基三甲氧基矽烷、3-縮水甘油氧基丙基三甲氧基矽烷、3-縮水甘油氧基丙基甲基二乙氧基矽烷、3-縮水甘油氧基丙基三乙氧基矽烷、3-丙烯醯氧基丙基三甲氧基矽烷、N-2-(胺乙基)-3-胺丙基甲基二甲氧基矽烷、3-胺丙基三甲氧基矽烷、3-胺丙基三乙氧基矽烷、N-苯基-3-胺丙基三甲氧基矽烷、3-脲基丙基三乙氧基矽烷、3-異氰酸丙基三乙氧基矽烷(isocyanatopropyltriethoxysilane)、三甲氧基辛醯基矽烷、三乙氧基辛醯基矽烷等。 More specifically, as non-limiting specific examples, it may be selected from any one or two or more of the group consisting of vinyltrimethoxysilane, vinyltriethoxysilane, 2-( 3,4-Epoxycyclohexyl)ethyltrimethoxysilane, 3-glycidoxypropyltrimethoxysilane, 3-glycidoxypropylmethyldiethoxysilane, 3-glycidoxy propylpropyltriethoxysilane, 3-propenyloxypropyltrimethoxysilane, N-2-(aminoethyl)-3-aminopropylmethyldimethoxysilane, 3-aminopropyl Trimethoxysilane, 3-aminopropyltriethoxysilane, N-phenyl-3-aminopropyltrimethoxysilane, 3-ureidopropyltriethoxysilane, 3-isocyanatopropyl Triethoxy silane (isocyanatopropyltriethoxysilane), trimethoxy octyl silane, triethoxy octyl silane, etc.
然而，在經如此表面處理的二氧化鈦不進行研磨處理而直接應用於水包油型配方的情形中，二氧化鈦可存在於所述配方的介面上，因此抑制分散相的穩定性，並造成皮膚刺激，且因此較佳地使二氧化鈦經受研磨而成為水分散的。此處，藉由適當地調整所述條件來實行研磨製程，藉此不會抑制用於顏料的二氧化鈦的膚色改善效果，且更有效地保證二氧化鈦複合粉末的水分散效能。作為具體實例，在研磨製程前的二氧化鈦可具有幾微米至幾十微米且更具體而言1微米至20微米的平均粒徑。在研磨製程之後，由於二氧化鈦藉由研磨製程而被粉碎，因此二氧化鈦的精細顆粒可具有較研磨製程前的平均粒徑小的平均粒徑，且更具體而言具有0.5微米至15微米的平均粒徑，但未必僅限於此。However, in the case where the thus surface-treated titanium dioxide is directly applied to an oil-in-water formulation without being ground, the titanium dioxide may be present at the interface of the formulation, thus inhibiting the stability of the dispersed phase and causing skin irritation, And therefore preferably the titanium dioxide is subjected to grinding to become water-dispersed. Here, the grinding process is carried out by appropriately adjusting the conditions, whereby the skin color improvement effect of the titanium dioxide used for the pigment is not inhibited, and the water dispersion performance of the titanium dioxide composite powder is more effectively ensured. As a specific example, the titanium dioxide before the grinding process may have an average particle size of several micrometers to several tens of micrometers, and more specifically, 1 micrometer to 20 micrometers. After the grinding process, since the titanium dioxide is pulverized by the grinding process, the fine particles of the titanium dioxide may have an average particle size smaller than that before the grinding process, and more specifically, have an average particle size of 0.5 to 15 microns path, but not necessarily limited to that.
除此之外，二氧化鈦、非離子界面活性劑及脂質可一起經受研磨，藉此進一步提高水分散效能。在不使用非離子界面活性劑及脂質的情形中，二氧化鈦的精細顆粒不會良好地分散，且在分散於水中時沈澱，抑或二氧化鈦的精細顆粒會凝聚於一起而降低組成物的穩定性。In addition, titanium dioxide, nonionic surfactants and lipids can be subjected to grinding together, thereby further enhancing the water dispersion performance. Without the use of nonionic surfactants and lipids, the fine particles of titanium dioxide do not disperse well and precipitate when dispersed in water, or the fine particles of titanium dioxide may agglomerate together to reduce the stability of the composition.
作為本發明的示例性實施例，具有彼此不同的親水親油均衡值的非離子界面活性劑及脂質可一起用於研磨製程中。具體而言，如上所述，非離子界面活性劑可具有12至18的親水親油均衡值，且脂質可具有1至5的親水親油均衡值。如此一來，當具有彼此不同的親水親油均衡值的兩種材料被混合使用並分散於水包油配方中時，可提高複合粉末的水分散穩定性。更佳地，非離子界面活性劑可具有13至17的親水親油均衡值，且脂質可具有1至3的親水親油均衡值。As an exemplary embodiment of the present invention, nonionic surfactants and lipids having different hydrophilic-lipophilic balances from each other may be used together in a polishing process. Specifically, as described above, the nonionic surfactant may have a hydrophilic-lipophilic balance of 12 to 18, and the lipid may have a hydrophilic-lipophilic balance of 1 to 5. In this way, when two materials having different hydrophilic-lipophilic balance values from each other are used in admixture and dispersed in an oil-in-water formulation, the water dispersion stability of the composite powder can be improved. More preferably, the nonionic surfactant may have a hydrophilic-lipophilic balance of 13 to 17, and the lipid may have a hydrophilic-lipophilic balance of 1 to 3.
非離子界面活性劑可具有12至18的親水親油均衡值，且若所述非離子界面活性劑為此項技術中常用者則可為任何界面活性劑而無特別限制，但例如可為環氧烷加成物型（alkyleneoxide adduct type）、多元醇型（polyhydric alcohol type）、環氧烷加成物-多元醇型（alkyleneoxide adduct-polyhydric alcohol type）或其混合物。更具體而言，作為非限制性具體實例，環氧烷加成物型可為選自由以下組成的群組的任一者或者二者或更多者：月桂醇聚醚-7、月桂醇聚醚-9、月桂醇聚醚-23、鯨蠟醇聚醚-10、鯨蠟醇聚醚-20、異鯨蠟醇聚醚-20、鯨蠟硬脂醇聚醚-12、鯨蠟硬脂醇聚醚-20、鯨蠟硬脂醇聚醚-25、鯨蠟硬脂醇聚醚-30、硬脂醇聚醚-10、硬脂醇聚醚-20、油醇聚醚-10、油醇聚醚-20、聚乙二醇（PEG）-20硬脂酸酯、PEG-30硬脂酸酯、PEG-40硬脂酸酯等，多元醇型可為選自由甘油、1,2-丙二醇、山梨醇、丁二醇、己二醇等組成的群組的任一者或者二或更多者，且環氧烷加成物-多元醇型可為選自由以下組成的群組的任一者或者二者或更多者：聚山梨醇酯20、聚山梨醇酯40、聚山梨醇酯60、聚山梨醇酯80、PEG 20甘油基異硬脂酸酯、PEG-40蓖麻油、PEG-40-氫化蓖麻油、PEG-60-氫化蓖麻油等。The non-ionic surfactant may have a hydrophilic-lipophilic balance value of 12 to 18, and if the non-ionic surfactant is commonly used in the art, it may be any surfactant without particular limitation, but may be, for example, a cyclic surfactant. An alkyleneoxide adduct type, a polyhydric alcohol type, an alkyleneoxide adduct-polyhydric alcohol type, or a mixture thereof. More specifically, as non-limiting specific examples, the alkylene oxide adduct type may be any one or two or more selected from the group consisting of: laureth-7, laureth Ether-9, Laureth-23, Ceteth-10, Ceteth-20, Isoceteth-20, Ceteeth-12, Cetearyl Aleth-20, Ceteeth-25, Ceteareth-30, Steareth-10, Steareth-20, Oleeth-10, Oil Alcohol polyether-20, polyethylene glycol (PEG)-20 stearate, PEG-30 stearate, PEG-40 stearate, etc. The polyol type can be selected from glycerol, 1,2- Any one or two or more of the group consisting of propylene glycol, sorbitol, butanediol, hexylene glycol, etc., and the alkylene oxide adduct-polyol type may be any one selected from the group consisting of One or both or more of: Polysorbate 20, Polysorbate 40, Polysorbate 60, Polysorbate 80, PEG 20 Glyceryl Isostearate, PEG-40 Castor Oil, PEG-40-hydrogenated castor oil, PEG-60-hydrogenated castor oil, etc.
脂質可具有1至5的親水親油均衡值，且若所述脂質為此項技術中常用者則可為任何脂質而無特別限制，但例如可為磷脂。更具體而言，作為非限制性具體實例，所述磷脂可為選自由以下組成的群組的任一者或者二者或更多者：具有C14至C20醯基（acyl）的磷脂醯膽鹼系磷脂、C14至C20磷脂醯乙醇胺系磷脂、C14至C20磷脂醯絲胺酸系磷脂、C14至C20磷脂酸系磷脂、C14至C20磷脂醯甘油系磷脂、C14至C20磷脂醯肌醇系磷脂、C14至C20溶血磷脂醯膽鹼系磷脂、具有C14至C20脂族基的鞘磷脂系磷脂及其氫化物，但未必僅限於此。The lipid may have a hydrophilic-lipophilic balance of 1 to 5, and may be any lipid without particular limitation if the lipid is commonly used in the art, but may be, for example, a phospholipid. More specifically, as a non-limiting specific example, the phospholipid can be any one or two or more selected from the group consisting of: a phospholipid choline having a C14 to C20 acyl group Phospholipids, C14-C20 Phosphatidylethanolamine Phospholipids, C14-C20 Phosphatidyl Serine Phospholipids, C14-C20 Phosphatidic Acid Phospholipids, C14-C20 Phosphatidyl Glycerol Phospholipids, C14-C20 Phosphatidyl Inositol Phospholipids, C14-C20 lysophospholipid choline-based phospholipids, sphingomyelin-based phospholipids having C14-C20 aliphatic groups, and hydrogenated products thereof, but not necessarily limited thereto.
作為較佳實例，非離子界面活性劑可為環氧烷加成物-多元醇型（alkyleneoxide adduct-polyhydric alcohol type），且脂質可為具有C14至C20醯基的磷脂醯膽鹼系磷脂（phosphatidylcholine-based phospholipid）。作為尤佳實例，有利的是使用聚山梨醇酯80作為非離子界面活性劑以及使用氫化卵磷脂作為脂質，以保證優異的配方穩定性以及亮白、滋潤及柔軟感覺。As a preferred example, the nonionic surfactant can be an alkyleneoxide adduct-polyhydric alcohol type, and the lipid can be a phosphatidylcholine phospholipid with C14 to C20 acyl groups -based phospholipid). As a particularly preferred example, it is advantageous to use polysorbate 80 as the nonionic surfactant and hydrogenated lecithin as the lipid to ensure excellent formulation stability as well as brightening, moisturizing and soft feel.
在本發明的示例性實施例中，可使經疏水性表面處理的二氧化鈦與非離子界面活性劑及脂質一起經受研磨製程而成為水分散的，且因此當將其應用於水包油配方時，可保證配方穩定性，且可減少皮膚刺激。具體而言，研磨製程並無特別限制，只要其為此項技術中通常實行的方法即可，且作為非限制性具體實例，其可為選自由以下組成的群組的任一者或者二者或更多者：輥研磨、球研磨、珠研磨、銼磨研磨、行星式研磨、噴射研磨及環形研磨。In an exemplary embodiment of the present invention, the hydrophobic surface-treated titanium dioxide can be subjected to a milling process together with nonionic surfactants and lipids to become water-dispersible, and thus when applied to oil-in-water formulations, Guaranteed formulation stability and reduced skin irritation. Specifically, the grinding process is not particularly limited as long as it is a method commonly practiced in the art, and as a non-limiting specific example, it can be any one or both selected from the group consisting of Or more: Roll mill, ball mill, bead mill, file mill, planetary mill, jet mill and ring mill.
在本發明的示例性實施例中，研磨製程並無顯著限制，但較佳地，調整例如正使用的二氧化鈦、非離子界面活性劑及脂質的組分等研磨製程條件。作為具體實例，研磨製程可在8000轉/分鐘（rmp）至10000轉/分鐘下實行60分鐘至90分鐘，但未必僅限於此。In the exemplary embodiment of the present invention, the polishing process is not significantly limited, but preferably, the polishing process conditions such as the components of titanium dioxide, nonionic surfactant and lipid being used are adjusted. As a specific example, the grinding process may be performed at 8000 revolutions per minute (rmp) to 10000 revolutions per minute (rmp) for 60 to 90 minutes, but is not necessarily limited thereto.
此外，本發明是有關於一種包含水分散二氧化鈦複合粉末的水包油型化妝品組成物，所述組成物可實現亮白、滋潤及柔軟的感覺以及高保濕感。Furthermore, the present invention relates to an oil-in-water cosmetic composition comprising a water-dispersed titanium dioxide composite powder, which can achieve brightening, moisturizing and soft feeling, and high moisturizing feeling.
具體而言，根據本發明的示例性實施例的水包油型化妝品組成物可包含水分散二氧化鈦複合粉末，所述水分散二氧化鈦複合粉末是藉由以研磨製程將包含以下的混合物粉碎來製備：經烷氧基矽烷進行疏水性表面處理的二氧化鈦；具有12至18的親水親油均衡值的非離子界面活性劑；以及具有1至5的親水親油均衡值的脂質。Specifically, the oil-in-water cosmetic composition according to an exemplary embodiment of the present invention may include a water-dispersed titanium dioxide composite powder prepared by pulverizing a mixture comprising: Titanium dioxide hydrophobic surface treated with alkoxysilane; nonionic surfactant having a hydrophilic-lipophilic balance of 12 to 18; and a lipid having a hydrophilic-lipophilic balance of 1 to 5.
如上所述，經疏水性表面處理的二氧化鈦可藉由經受研磨而有效地分散於作為水包油型化妝品組成物的連續相的外部水相中，且可保證優異的配方穩定性及皮膚安全性。As described above, the hydrophobic surface-treated titanium dioxide can be effectively dispersed in the external aqueous phase which is the continuous phase of the oil-in-water cosmetic composition by being subjected to grinding, and can ensure excellent formulation stability and skin safety .
在根據示例性實施例的水包油型化妝品組成物中，在整體組成物中可包含0.1重量%至10重量%、較佳地0.5重量%至5重量%、更佳地1重量%至3重量%的水分散二氧化鈦複合粉末。在此範圍內，膚色改良效果優異，且皮膚刺激可顯著減少。In the oil-in-water cosmetic composition according to the exemplary embodiment, 0.1% to 10% by weight, preferably 0.5% to 5% by weight, more preferably 1% to 3% by weight may be included in the overall composition % by weight of water-dispersed titanium dioxide composite powder. Within this range, the skin tone improvement effect is excellent, and skin irritation can be significantly reduced.
此種水包油型化妝品組成物可用於例如皮膚、洗液或香精等基礎化妝品，用於例如妝前底霜（makeup base）、粉底、BB霜或遮瑕膏等彩妝，用於例如防曬劑等功能性化妝品等。Such oil-in-water cosmetic compositions can be used in base cosmetics such as skin, lotions or fragrances, in make-up such as makeup bases, foundations, BB creams or concealers, for example in sunscreens, etc. Functional cosmetics, etc.
作為具體實例，若水包油型化妝品組成物用於紫外線防護，則其可更包含防曬劑，所述防曬劑可為有機防曬劑、無機防曬劑或其混合物。有機防曬劑可為選自由以下組成的群組的任一者或者二者或更多者：胡莫柳酯（homosalate）、水楊酸乙基己基酯（ethylhexylsalicylate）、苯基苯並咪唑磺酸（phenylbenzimidazole sulfonic acid）、氰雙苯丙烯酸辛酯（octocrylene）、甲氧基肉桂酸乙基己基酯（ethylhexylmethoxycinnamate）、棕櫚酸乙基己基酯（ethylhexylpalmitate）、丁基甲氧基二苯甲醯基甲烷（butylmethoxydibenzoylmethane）、4-甲基苯亞甲基樟腦（4-methylbenzylidene camphor）、對甲氧基肉桂酸異戊酯（isoamyl-p-methoxycinnamate）、雙-乙基己氧苯酚甲氧苯基三嗪（bis-ethylhexyloxyphenolmethoxyphenyltriazine）等，且無機防曬劑可為選自由二氧化鈦、氧化鋅、氧化鐵等組成的群組的任一者或者二者或更多者，但未必僅限於此。防曬劑的含量並無特別限制，而是可為所述組成物的總重量的1重量%至25重量%、較佳地5重量%至20重量%。As a specific example, if the oil-in-water cosmetic composition is used for UV protection, it may further comprise a sunscreen, which may be an organic sunscreen, an inorganic sunscreen, or a mixture thereof. The organic sunscreen may be any one or two or more selected from the group consisting of: homosalate, ethylhexylsalicylate, phenylbenzimidazole sulfonic acid (phenylbenzimidazole sulfonic acid), octocrylene, ethylhexylmethoxycinnamate, ethylhexylpalmitate, butylmethoxydibenzoylmethane ), 4-methylbenzylidene camphor (4-methylbenzylidene camphor), isoamyl-p-methoxycinnamate (isoamyl-p-methoxycinnamate), bis-ethylhexyloxyphenol methoxyphenyl triazine (bis -ethylhexyloxyphenolmethoxyphenyltriazine), etc., and the inorganic sunscreen agent can be any one or two or more selected from the group consisting of titanium dioxide, zinc oxide, iron oxide, etc., but not necessarily limited thereto. The content of the sunscreen agent is not particularly limited, but may be 1% to 25% by weight, preferably 5% to 20% by weight, based on the total weight of the composition.
此外，水包油型化妝品組成物可更包含處於不會降低配方穩定性及皮膚安全性的範圍內的界面活性劑、抗氧化劑、穩定劑、pH調節劑、防腐劑、消毒劑、染料、香料、珠光劑等，上述者根據化妝品組成物的目的而常用於此項技術中。In addition, the oil-in-water cosmetic composition may further contain surfactants, antioxidants, stabilizers, pH adjusters, preservatives, disinfectants, dyes, fragrances within a range that does not reduce formulation stability and skin safety , pearlescent agents, etc., which are commonly used in the art depending on the purpose of the cosmetic composition.
以下，將藉由以下實例更詳細地闡述根據本發明的水分散二氧化鈦複合粉末及水包油型化妝品組成物。然而，以下實例僅為用於詳細闡述本發明的參考，且本發明並不僅限於此，而是可實作為各種形式。此外，除非另外定義，否則所有技術及科學用語具有與熟習本發明所屬技術者所通常理解的意義相同的意義。本文中在說明中所用的用語僅用於有效地闡述某一實例，而並不旨在限制本發明。此外，除非在上下文中另外陳述，否則說明書及隨附申請專利範圍中所用的單數形式亦可包括複數形式。此外，除非另外陳述，否則所添加材料的單位可為重量%。Hereinafter, the water-dispersed titanium dioxide composite powder and the oil-in-water cosmetic composition according to the present invention will be explained in more detail by the following examples. However, the following examples are only references for explaining the present invention in detail, and the present invention is not limited thereto, but can be implemented in various forms. Also, unless otherwise defined, all technical and scientific terms have the same meaning as commonly understood by those skilled in the art to which this invention belongs. The terms used in the description herein are used to effectively illustrate an example only, and are not intended to limit the invention. Furthermore, as used in the specification and the scope of the appended claims, the singular also includes the plural unless the context dictates otherwise. Furthermore, unless otherwise stated, the unit of material added may be % by weight.
[製備實例1][Preparation Example 1]
藉由研磨製程將50重量%的二氧化鈦（CI 77891）、20重量%的丁二醇、10重量%的聚山梨醇酯80、10重量%的氫氧化鋁、5重量%的氫化卵磷脂及5重量%的三乙氧基辛醯基矽烷粉碎，並進行混合以製備二氧化鈦複合粉末。50% by weight of titanium dioxide (CI 77891), 20% by weight of butanediol, 10% by weight of polysorbate 80, 10% by weight of aluminum hydroxide, 5% by weight of hydrogenated lecithin and 5 % by weight of triethoxyoctanoylsilane was pulverized and mixed to prepare a titanium dioxide composite powder.
[比較製備實例1][Comparative Preparation Example 1]
將76.9重量%的二氧化鈦（CI 77891）、15.4重量%的氫氧化鋁及7.7重量%的三乙氧基辛醯基矽烷混合以製備二氧化鈦複合粉末。76.9 wt % of titanium dioxide (CI 77891), 15.4 wt % of aluminum hydroxide, and 7.7 wt % of triethoxyoctanoylsilane were mixed to prepare a titanium dioxide composite powder.
[比較製備實例2][Comparative Preparation Example 2]
將50重量%的二氧化鈦（CI 77891）、20重量%的丁二醇、10重量%的聚山梨醇酯80、10重量%的氫氧化鋁、5重量%的氫化卵磷脂及5重量%的三乙氧基辛醯基矽烷混合以製備二氧化鈦複合粉末，但不實行研磨製程。50% by weight of titanium dioxide (CI 77891), 20% by weight of butanediol, 10% by weight of polysorbate 80, 10% by weight of aluminum hydroxide, 5% by weight of hydrogenated lecithin, and 5% by weight of trisamine Ethoxyoctylsilane was mixed to prepare TiO2 composite powder, but no grinding process was performed.
[比較製備實例3][Comparative Preparation Example 3]
將52.6重量%的二氧化鈦（CI 77891）、21.1重量%的丁二醇、10.5重量%的聚山梨醇酯80、10.5重量%的氫氧化鋁、及5.3重量%的三乙氧基辛醯基矽烷混合以製備二氧化鈦複合粉末。52.6 wt% titanium dioxide (CI 77891), 21.1 wt% butanediol, 10.5 wt% polysorbate 80, 10.5 wt% aluminum hydroxide, and 5.3 wt% triethoxyoctanoylsilane were mixed to Preparation of titanium dioxide composite powder.
[實例1以及比較例1至比較例3][Example 1 and Comparative Examples 1 to 3]
根據表1中列出的組成（重量%）將製備實例1或比較製備實例1至比較製備實例3中製備的二氧化鈦複合粉末混合以製備防曬劑。The titanium dioxide composite powders prepared in Preparation Example 1 or Comparative Preparation Example 1 to Comparative Preparation Example 3 were mixed according to the compositions (% by weight) listed in Table 1 to prepare a sunscreen.
[表1]
[皮膚穩定性測試][Skin Stability Test]
平均年齡為26.6的33個組員（男性10名以及女性23名）藉由C-HPIT 2003(3)方法進行了皮膚刺激測試。將在實例1以及比較例1至比較例3中製備的防曬劑分別施加於面部皮膚、面部眼睛下面的顴骨上，且在20分鐘之後，對皮膚刺激程度進行量測並數位化，且在表2中列出結果。在本文中，刺激值越高，皮膚刺激程度越高。Thirty-three panelists (10 males and 23 females) with an average age of 26.6 underwent skin irritation testing by the C-HPIT 2003(3) method. The sunscreens prepared in Example 1 and Comparative Examples 1 to 3 were applied to the facial skin, the cheekbones under the facial eyes, respectively, and after 20 minutes, the degree of skin irritation was measured and digitized, and The results are listed in Table 2. In this context, the higher the irritation value, the higher the degree of skin irritation.
[表2]
[配方穩定性測試][Formula Stability Test]
將在實例1以及比較例1至比較例3中製備的防曬劑置於室溫（25℃）下30天，然後評估所述配方的狀態，且在表3中列出結果：The sunscreens prepared in Example 1 and Comparative Examples 1 to 3 were left at room temperature (25°C) for 30 days, then the state of the formulations was evaluated and the results are listed in Table 3:
[表3]
根據本發明的水分散二氧化鈦複合粉末可藉由使用經烷氧基矽烷進行疏水性表面處理的二氧化鈦來維持白色面容作為皮膚膚色改善效果；藉由用研磨製程將二氧化鈦處理成水分散的，無論是否使用相同含量的二氧化鈦均顯著減少皮膚刺激；且藉由在研磨製程中使用二氧化鈦、具有12至18的親水親油均衡值的非離子界面活性劑及具有1至5的親水親油均衡值的脂質的混合物，即使在分散於水包油型配方中的情形中亦非常穩定地維持配方。The water-dispersed titanium dioxide composite powder according to the present invention can maintain a white face as a skin complexion-improving effect by using titanium dioxide hydrophobic surface-treated with alkoxysilane; by treating the titanium dioxide to be water-dispersed by a grinding process, whether or not Skin irritation was significantly reduced using the same levels of titanium dioxide; and by using titanium dioxide, a nonionic surfactant with a hydrophilic-lipophilic balance of 12 to 18, and a lipid with a hydrophilic-lipophilic balance of 1 to 5 in the grinding process The mixture maintains the formulation very stably even when dispersed in oil-in-water formulations.
在上文中，儘管已藉由具體物質以及有限實例及比較例闡述了本發明，但提供所述具體物質以及有限實例及比較例僅為了有助於完全理解本發明。因此，本發明並不僅限於以上實例。熟習本發明所屬技術者可自本說明做出各種潤飾及改變。In the foregoing, although the present invention has been described by means of specific substances and limited examples and comparative examples, the specific substances and limited examples and comparative examples are provided only to facilitate a complete understanding of the present invention. Therefore, the present invention is not limited to the above examples only. Various modifications and changes can be made by those skilled in the art from this description.
因此，本發明的精神不應僅限於上述實例及以下申請專利範圍，且與申請專利範圍均等或等效的修改的全部旨在落於本發明的範圍及精神內。Therefore, the spirit of the present invention should not be limited to the above examples and the following claims, and all modifications equivalent or equivalent to the claims are intended to fall within the scope and spirit of the present invention.
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| KR1020150151441A KR102417771B1 (en) | 2015-10-30 | 2015-10-30 | Water-dispersible titanium dioxide composite powder |
| KR10-2015-0151441 | 2015-10-30 |
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| JP7185143B2 (en) | 2018-01-29 | 2022-12-07 | 石原産業株式会社 | Titanium dioxide aqueous dispersion and method for producing the same |
| CN110123651A (en) * | 2019-06-10 | 2019-08-16 | 天津先光化妆品有限公司 | A kind of water-soluble titanium dioxide dispersion pulp |
| CN110354027A (en) * | 2019-08-28 | 2019-10-22 | 重庆医科大学 | A kind of multi-functional lotion and preparation method thereof |
| CN112190491B (en) * | 2020-10-15 | 2023-03-31 | 广州市科能化妆品科研有限公司 | High-dispersity cosmetic inorganic pigment color paste and preparation method and application thereof |
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| EP1700825A1 (en) * | 2004-12-23 | 2006-09-13 | Degussa AG | Surface and structure modified titanium dioxide |
| US20070128137A1 (en) * | 2005-12-02 | 2007-06-07 | Naohisa Yoshimi | Water in oil emulsion compositions containing siloxane elastomers |
| US20100003290A1 (en) * | 2008-09-28 | 2010-01-07 | Kobo Products, Inc. | Oil and water repellent cosmetic powder and methods of making and using same |
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| KR102417771B1 (en) | 2022-07-06 |
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