TWI746488B - Silicone-in-water type emulsion cosmetic composition comprising silicone oil and method for preparing same - Google Patents
Silicone-in-water type emulsion cosmetic composition comprising silicone oil and method for preparing same Download PDFInfo
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Abstract
Description
本揭露關於矽油(silicone oil)的水包矽(silicone-in-water)型乳液化妝品組成物及其製備方法。The present disclosure relates to a silicone-in-water emulsion cosmetic composition of silicone oil and a preparation method thereof.
矽油用於在化妝品組成物中導入明亮使用感。當矽油用於乳液配方時，考慮到乳液作用(emulsification)之界面活性劑的易於選擇性，常使用以矽油作為外部相且水作為內部相的矽包水(water-in-silicone, W/S)配方。Silicone oil is used to introduce a bright feeling of use in cosmetic compositions. When silicone oil is used in emulsion formulations, considering the ease of selection of surfactants for emulsification, water-in-silicone (W/S) with silicone oil as the external phase and water as the internal phase is often used. )formula.
在以矽油作為內部相且水作為外部相之水包矽(silicone-in-water, S/W)型配方案例中，源自矽的絲綢(silky)使用感及以水作為外部相之清爽感之結合極大化清爽使用感。不過，在此案例中，當使用傳統界面活性劑時，乳液顆粒的界面不穩定。因此，必須加入增稠劑(thickener)或蠟(wax)至外部相中，以增加外部相的黏度或硬度，以及使用特定界面活性劑用以強化界面膜層。因此，因界面活性劑及增稠劑而具有高黏度之所得配方，可能無法提供所需的清爽使用感。此限制了S/W配方的應用。In the case of a silicone-in-water (S/W) type formula with silicone oil as the internal phase and water as the external phase, the feeling of use of silk derived from silicon and the refreshing feeling of water as the external phase The combination maximizes the refreshing feeling of use. However, in this case, when traditional surfactants are used, the interface of the emulsion particles is unstable. Therefore, it is necessary to add a thickener or wax to the external phase to increase the viscosity or hardness of the external phase, and to use a specific surfactant to strengthen the interfacial film layer. Therefore, the resulting formulations with high viscosity due to surfactants and thickeners may not provide the desired refreshing feeling of use. This limits the application of S/W recipes.
包含聚合物之球形微粒取決於其製作方法而具有可控制的尺寸及形狀，因此有高應用性。舉例而言，已有一種皮克林乳液(Pickering emulsion)，其使用球形微粒形成穩定的***液(macroemulsion)顆粒。水相與油相之間的接觸角(θ)隨著球形顆粒的親水性/疏水性而改變。當接觸角大於90°，形成O/W乳液顆粒。同理，當接觸角小於90°，形成 W/O乳液顆粒。The polymer-containing spherical particles have a controllable size and shape depending on the production method, and therefore have high applicability. For example, there is a Pickering emulsion that uses spherical particles to form stable macroemulsion particles. The contact angle (θ) between the water phase and the oil phase changes with the hydrophilicity/hydrophobicity of the spherical particles. When the contact angle is greater than 90°, O/W emulsion particles are formed. Similarly, when the contact angle is less than 90°, W/O emulsion particles are formed.
此外，已經有一些嘗試要將兩親性質(也就是親水性及疏水性兩者)導入球形微粒中，以求獲得新穎的各向異性粉末。此可由Janus球形顆粒(Janus spherical particles)來闡釋。不過，此類球形顆粒因為其形態(morphological)限制而具有化學各向異性的限制。換言之，儘管這些顆粒為形態各向異性，其可能整體為疏水性或親水性，因此具有限制的化學各向異性。In addition, there have been some attempts to introduce amphiphilic properties (that is, both hydrophilic and hydrophobic) into spherical particles in order to obtain novel anisotropic powders. This can be explained by Janus spherical particles. However, such spherical particles have the limitation of chemical anisotropy due to their morphological limitation. In other words, although these particles are morphologically anisotropic, they may be hydrophobic or hydrophilic as a whole, and therefore have limited chemical anisotropy.
因此，已有一些嘗試要藉由控制幾何形狀以及導入化學各向異性，以獲得表面活化各向異性粉末。不過，儘管此兩親各向異性粉末表現出高應用性，迄今為止，都尚未發展出兩親各向異性粉末(amphiphilic anisotropic powder)的量產方法。此外，要以工業規模大量生產均勻兩親各向異性粉末相當困難，導致無法實際應用。Therefore, there have been some attempts to obtain surface activated anisotropic powders by controlling the geometry and introducing chemical anisotropy. However, although this amphiphilic anisotropic powder exhibits high applicability, a mass production method for amphiphilic anisotropic powder has not yet been developed. In addition, it is quite difficult to mass-produce uniform amphiphilic anisotropic powders on an industrial scale, resulting in impractical applications.
[技術問題] 本揭露欲解決之技術問題為，提供具有優異乳液穩定性之水包矽(S/W)型乳液化妝品組成物。[Technical Problem] The technical problem to be solved by this disclosure is to provide a silicone-in-water (S/W) emulsion cosmetic composition with excellent emulsion stability.
本揭露欲解決之另一技術問題為，提供具有最大化不黏膩的使用感之乳液化妝品組成物。Another technical problem to be solved by the present disclosure is to provide an emulsion cosmetic composition with a maximum non-sticky feeling in use.
本揭露欲解決之另一技術問題為，提供具有明亮使用感之乳液化妝品組成物。Another technical problem that the present disclosure intends to solve is to provide an emulsion cosmetic composition with bright use feeling.
本揭露欲解決之另一技術問題為，提供一種乳液化妝品組成物，其具有絲綢(silky)以及霧面(matte)的定妝感。Another technical problem that the present disclosure intends to solve is to provide an emulsion cosmetic composition with silky and matte makeup setting.
本揭露欲解決之另一技術問題為，提供一種乳液化妝品組成物，其具有優異穩定性同時提供低黏度的流動性。Another technical problem to be solved by the present disclosure is to provide an emulsion cosmetic composition that has excellent stability and low viscosity fluidity.
本揭露欲解決之另一技術問題為，提供一種乳液化妝品組成物，其於皮脂吸收粉末(sebum-absorbing powder)存在下具有優異乳液穩定性。Another technical problem to be solved by the present disclosure is to provide an emulsion cosmetic composition, which has excellent emulsion stability in the presence of sebum-absorbing powder.
[技術解答] 在一通用態樣中，提供一種包含兩親各向異性粉末及矽油之乳液型化妝品組成物，其中該兩親各向異性粉末包含第一親水性聚合物球體(hydrophilic polymer spheroid)以及第二疏水性聚合物球體(hydrophobic polymer spheroid)，該第一聚合物球體及該第二聚合物球體係以一聚合物球體至少部分穿透至另一聚合物球體的結構彼此連結，該第一聚合物球體具有核-殼結構(core-shell structure)，且該殼具有一官能基。[Technical Solution] In a general aspect, there is provided an emulsion cosmetic composition comprising amphiphilic anisotropic powder and silicone oil, wherein the amphiphilic anisotropic powder contains a first hydrophilic polymer spheroid. And a second hydrophobic polymer spheroid. The first polymer spheroid and the second polymer spheroid are connected to each other in a structure in which one polymer spheroid at least partially penetrates to the other polymer spheroid. A polymer sphere has a core-shell structure, and the shell has a functional group.
[有益效果] 在一態樣中，本揭露提供一種水包矽型乳液化妝品組成物，其具有優異乳液穩定性。[Beneficial Effects] In one aspect, the present disclosure provides a silicone-in-water emulsion cosmetic composition, which has excellent emulsion stability.
在另一態樣中，本揭露提供一種乳液化妝品組成物，其具有最大化的不黏膩使用感。In another aspect, the present disclosure provides an emulsion cosmetic composition that has a maximized non-sticky use feeling.
在另一態樣中，本揭露提供一種乳液化妝品組成物，其具有明亮使用感。In another aspect, the present disclosure provides an emulsion cosmetic composition that has a bright use feeling.
在另一態樣中，本揭露提供一種乳液化妝品組成物，其具有絲綢以及霧面的定妝感。In another aspect, the present disclosure provides an emulsion cosmetic composition, which has a silky and matte makeup setting feeling.
在另一態樣中，本揭露提供一種乳液化妝品組成物，其具有優異穩定性同時提供低黏度的流動性。In another aspect, the present disclosure provides an emulsion cosmetic composition that has excellent stability and low viscosity fluidity.
在另一態樣中，本揭露提供一種乳液化妝品組成物，其於皮脂吸收粉末存在下具有優異乳液穩定性。In another aspect, the present disclosure provides an emulsion cosmetic composition that has excellent emulsion stability in the presence of sebum absorption powder.
現將參考呈現示範實施例的伴隨圖式，於後文中更全面地說明示範實施例。不過，此揭露可以被包含在許多不同形式中，而且不應被推論為限定至本文提出的示範實施例。更準確地說，提供這些實施例是為了讓本揭露能夠透徹且完整，且將能全面傳達本揭露之範籌給本領域之技術人員。在圖式中，為了清楚，圖式的形狀、尺寸及區域等等可能會被誇張化。此外，儘管為了便於描述而示出部分構成元件，但是本領域技術人員可以容易地理解剩餘部分。此外，本領域技術人員將理解，在不脫離由所附權利要求限定的本公開的範圍的情況下，可以對形式和細節進行各種改變。The exemplary embodiments will now be described more fully in the following with reference to accompanying drawings showing exemplary embodiments. However, this disclosure can be included in many different forms, and should not be inferred to be limited to the exemplary embodiments presented herein. To be more precise, these embodiments are provided to make this disclosure thorough and complete, and to fully convey the scope of this disclosure to those skilled in the art. In the drawings, the shape, size, and area of the drawings may be exaggerated for clarity. In addition, although some constituent elements are shown for ease of description, those skilled in the art can easily understand the remaining parts. In addition, those skilled in the art will understand that various changes in form and details can be made without departing from the scope of the present disclosure defined by the appended claims.
在本文中，「經取代」表示在此描述的官能基的至少一個氫原子經鹵原子(F, Cl, Br 或 I)、氫氧基(hydroxyl group)、硝基(nitro group)、亞胺基(imino group)( =NH、=NR，其中 R 為C1-C10的烷基)、甲脒基(amidino group)、胼或腙基(hydrazine or hydrazone group)、羧基(carboxyl group)、經取代或未經取代之C1-C20的烷基、經取代或未經取代之C3-C30的雜芳基(heteroaryl group)、或經取代或未經取代之C2-C30的雜環烷基(heterocycloalkyl group)取代，除非另有描述。As used herein, “substituted” means that at least one hydrogen atom of the functional group described herein is passed through a halogen atom (F, Cl, Br or I), hydroxyl group, nitro group, or imine. Imino group (=NH, =NR, where R is C1-C10 alkyl), amidino group, hydrazine or hydrazone group, carboxyl group, substituted Or unsubstituted C1-C20 alkyl, substituted or unsubstituted C3-C30 heteroaryl group (heteroaryl group), or substituted or unsubstituted C2-C30 heterocycloalkyl group (heterocycloalkyl group) ) Is substituted unless otherwise described.
在本文中，「(甲基)丙烯基((meth)arcyl)」表示丙烯基(acryl)及/或甲基丙烯基(methacryl)。In this context, "(meth)arcyl" means acryl and/or methacryl.
在本文中，兩親各向異性粉末的顆粒尺寸，是測量最大長度，其為粉末顆粒的最大長度。在本文中，兩親各向異性粉末的顆粒尺寸範圍表示該兩親各向異性粉末的組成中至少95%屬於該對應範圍。In this article, the particle size of the amphiphilic anisotropic powder is the measured maximum length, which is the maximum length of the powder particles. In this context, the particle size range of the amphiphilic anisotropic powder means that at least 95% of the composition of the amphiphilic anisotropic powder falls within the corresponding range.
在本文中，乳液顆粒的平均顆粒直徑表示每一顆粒直徑的平均。在本文中，乳液顆粒的平均顆粒直徑範圍表示該乳液顆粒的組成中至少95%屬於該對應範圍。In this context, the average particle diameter of the emulsion particles means the average of each particle diameter. In this context, the average particle diameter range of the emulsion particles means that at least 95% of the composition of the emulsion particles falls within the corresponding range.
在本身中，皮脂吸收粉末的平均顆粒直徑表示體積平均顆粒直徑，其是基於顆粒尺寸分佈來計算該體積平均，該顆粒尺寸分佈是由測定顆粒尺寸分佈的已知方法，如電子顯微鏡圖相的觀察、雷射繞射等等，來測定。In itself, the average particle diameter of the sebum absorption powder means the volume average particle diameter, which is calculated based on the particle size distribution, which is determined by the known method of measuring the particle size distribution, such as the image of the electron microscope. Observation, laser diffraction, etc., to determine.
在一態樣中，提供了包含兩親各向異性粉末以及矽油的水包矽(S/W)型乳液化妝品組成物。In one aspect, there is provided a silicon-in-water (S/W) emulsion cosmetic composition containing amphiphilic anisotropic powder and silicone oil.
根據一實施例，以組成物的總重量為基準，矽油的使用量可為5重量百分比(wt%)以上、6 wt%以上、7 wt%以上、8 wt%以上、9 wt%以上、或10 wt%以上；以及45%以下、44 wt%以下、43 wt%以下、42 wt%以下、41 wt%以下、 40 wt%以下、39 wt%以下、38 wt%以下、37 wt%以下、36 wt%以下、35 wt%以下、34 wt%以下、 33 wt%以下、32 wt%以下、31 wt%以下、或30 wt%以下。舉例而言，矽油的使用量可為5-45wt%，較佳為5-40wt%。水包矽型乳液配方能夠在上述定義範圍內形成。According to an embodiment, based on the total weight of the composition, the amount of silicone oil used may be 5 wt% or more, 6 wt% or more, 7 wt% or more, 8 wt% or more, 9 wt% or more, or 10 wt% or more; and 45% or less, 44 wt% or less, 43 wt% or less, 42 wt% or less, 41 wt% or less, 40 wt% or less, 39 wt% or less, 38 wt% or less, 37 wt% or less, 36 wt% or less, 35 wt% or less, 34 wt% or less, 33 wt% or less, 32 wt% or less, 31 wt% or less, or 30 wt% or less. For example, the amount of silicone oil used can be 5-45wt%, preferably 5-40wt%. The silicone-in-water emulsion formula can be formed within the above-defined range.
矽油可以提供具有絲綢且明亮使用感的配方，以及形成乳液配方的內層相。根據本揭露實施例的乳液化妝品組成物可形成如後文所述的***液(macroemulsion)顆粒。因此，乳液顆粒中的矽油在使用中(例如應用至皮膚上)被釋出時可提供獨特使用感。Silicone oil can provide a silky and bright use-feeling formula, as well as forming the inner phase of the emulsion formula. The emulsion cosmetic composition according to the embodiment of the present disclosure can form macroemulsion particles as described later. Therefore, the silicone oil in the emulsion particles can provide a unique feeling of use when it is released during use (for example, when applied to the skin).
根據本揭露之實施例，矽油可包含聚二甲基矽氧烷(dimethicone)、環甲聚矽氧烷(cyclomethicone)、烷基聚三甲基矽氧烷(alkyltrimethicone)、甲基苯基矽氧烷(methylphenylsiloxane)、三矽氧烷(trisiloxane)等等。舉例而言，矽油可為十甲基環五矽氧烷(decamethylcyclopentasiloxane)或是三甲基矽烷氧基矽酸酯(trimethylsiloxysilicate)，但不限於此。According to an embodiment of the present disclosure, the silicone oil may include dimethicone, cyclomethicone, alkyltrimethicone, and methyl phenyl silicone Methylphenylsiloxane, trisiloxane, etc. For example, the silicone oil can be decamethylcyclopentasiloxane or trimethylsiloxysilicate, but it is not limited thereto.
根據本揭露之實施例，可形成含有以矽穩定作為內層相的水包矽型乳液組成物，因此可提供最大限定的清爽使用感。According to the embodiments of the present disclosure, a silicon-in-water emulsion composition containing a silicon stabilizer as an inner phase can be formed, so that it can provide the most limited refreshing feeling of use.
根據另一實施例，組成物可具有黏度為7000 cps以下可流動配方。其可以在不使用過量增稠劑、蠟或界面活性劑的情況下形成穩定的乳液配方，因此可以得到柔軟低黏度配方。舉例而言，該組成物之黏度可以是1000 cps以上、1100 cps以上、1200 cps以上、1300 cps以上、1400 cps以上、1500 cps以上、1600 cps以上、1700 cps以上、1800 cps以上、1900 cps以上、2000 cps以上、2100 cps以上、2200 cps以上、 2300 cps以上、2400 cps以上、或2500 cps以上；以及20000 cps以下、19000 cps以下、18000 cps以下、17000 cps以下、16000 cps以下、15000 cps以下、14000 cps以下、13000 cps以下、12000 cps以下、11000 cps以下、10000 cps以下、8900 cps以下、8800 cps以下、8700 cps以下、8600 cps以下、8500 cps以下、8400 cps以下、 8300 cps以下、8200 cps以下、8100 cps以下、8000 cps以下、7900 cps以下、 7800 cps以下、7700 cps以下、7600 cps以下、7500 cps以下、7400 cps以下、 7300 cps以下、7200 cps以下、7100 cps以下、7000 cps以下、6900 cps以下、 6800 cps以下、6700 cps以下、6600 cps以下、6500 cps以下、6400 cps以下、6300 cps以下、6200 cps以下、6100 cps以下、或6000 cps以下。舉例而言，該黏度可以是1000-20000 cps、1000-10000 cps、1500-7000 cps、或2000-6000 cps。較佳地，該黏度可為1000-10000 cps、1000-3000 cps、或5000-7000 cps。According to another embodiment, the composition may have a flowable formula with a viscosity of 7000 cps or less. It can form a stable emulsion formula without using excessive thickeners, waxes or surfactants, so a soft and low-viscosity formula can be obtained. For example, the viscosity of the composition can be 1000 cps or more, 1100 cps or more, 1200 cps or more, 1300 cps or more, 1400 cps or more, 1500 cps or more, 1600 cps or more, 1700 cps or more, 1800 cps or more, or 1900 cps or more , 2000 cps or more, 2100 cps or more, 2200 cps or more, 2300 cps or more, 2400 cps or more, or 2500 cps or more; and 20000 cps or less, 19000 cps or less, 18000 cps or less, 17000 cps or less, 16000 cps or less, 15000 cps or less , 14000 cps or less, 13000 cps or less, 12000 cps or less, 11000 cps or less, 10000 cps or less, 8900 cps or less, 8800 cps or less, 8700 cps or less, 8600 cps or less, 8500 cps or less, 8400 cps or less, 8300 cps or less, 8200 cps or less, 8100 cps or less, 8000 cps or less, 7900 cps or less, 7800 cps or less, 7700 cps or less, 7600 cps or less, 7500 cps or less, 7400 cps or less, 7300 cps or less, 7200 cps or less, 7100 cps or less, 7000 cps or less , 6900 cps or less, 6800 cps or less, 6700 cps or less, 6600 cps or less, 6500 cps or less, 6400 cps or less, 6300 cps or less, 6200 cps or less, 6100 cps or less, or 6000 cps or less. For example, the viscosity can be 1000-20000 cps, 1000-10000 cps, 1500-7000 cps, or 2000-6000 cps. Preferably, the viscosity can be 1000-10000 cps, 1000-3000 cps, or 5000-7000 cps.
根據另一實施例，兩親各向異性粉末包含第一親水性聚合物球體以及第二疏水性聚合物球體，其中該第一聚合物球體及該第二聚合物球體係以一聚合物球體至少部分穿透至另一聚合物球體的結構彼此連結，該第一聚合物球體具有核-殼結構，且該殼具有一官能基。According to another embodiment, the amphiphilic anisotropic powder comprises a first hydrophilic polymer sphere and a second hydrophobic polymer sphere, wherein the first polymer sphere and the second polymer sphere system use a polymer sphere at least The structures partially penetrating to another polymer sphere are connected to each other, the first polymer sphere has a core-shell structure, and the shell has a functional group.
如本文所用，球體表示聚合物形成的單一個體。舉例而言，其可以具有球形、桶形(globoidal)、卵形形狀，以及根據個體部位中最大長度的微米規模或奈米規模長軸長度。As used herein, a sphere refers to a single entity formed by a polymer. For example, it may have a spherical shape, a globoidal shape, an oval shape, and a micro-scale or nano-scale long axis length according to the maximum length in an individual part.
根據一實施例，第二聚合物球體與第一聚合物球體的核可包含乙烯基聚合物(vinyl polymers)，且第一聚合物球體的殼可包含乙烯基單體與含官能基單體的共聚物(copolymer)。According to an embodiment, the cores of the second polymer sphere and the first polymer sphere may include vinyl polymers, and the shell of the first polymer sphere may include vinyl monomers and functional group-containing monomers. Copolymer.
根據另一實施例，乙烯基聚合物可包含乙烯基芳香聚合物，特別是聚苯乙烯(polystyrene)。According to another embodiment, the vinyl polymer may include a vinyl aromatic polymer, particularly polystyrene.
根據另一實施例，乙烯基單體可包含乙烯基芳香單體。舉例而言，乙烯基單體可為經取代或未經取代苯乙烯。According to another embodiment, the vinyl monomer may include a vinyl aromatic monomer. For example, the vinyl monomer can be substituted or unsubstituted styrene.
根據另一實施例，官能基可包含矽氧烷(siloxane)。According to another embodiment, the functional group may include siloxane.
根據另一實施例，含官能基單體可以是含矽氧烷(甲基)丙烯酸酯，特別是至少一選自由3-(三甲氧基矽烷基)丙基丙烯酸酯(3-(trimethoxysilyl)propyl acrylate)、3-(三甲氧基矽烷基)丙基甲基丙烯酸酯(3-(trimethoxysilyl)propyl methacrylate)、乙烯基三乙氧基矽烷(vinyltriethoxysilane)以及乙烯基三甲氧基矽烷(vinyltrimethoxysilane)或上述組合所組成之族群。According to another embodiment, the functional group-containing monomer may be a silicone-containing (meth)acrylate, particularly at least one selected from 3-(trimethoxysilyl)propyl acrylate (3-(trimethoxysilyl)propyl acrylate), 3-(trimethoxysilyl)propyl methacrylate, vinyltriethoxysilane and vinyltrimethoxysilane or the above The ethnic group formed by the combination.
根據另一實施例，該聚合物球體之殼可更具有接於其上之親水性官能基。According to another embodiment, the shell of the polymer sphere may further have hydrophilic functional groups attached to it.
根據另一實施例，該親水性官能基可為負電性或正電性官能基、或聚乙二醇(polyethylene glycol, PEG)型官能基，且可包含至少一選自由羧酸酯基團(carboxylate group)、碸基團(sulfone group)、磷酸酯基團(phosphate group)、胺基團(amino group)、烷氧基團(alkoxy group)、酯基團(ester group)、乙酸酯基團(acetate group)、聚乙二醇基團(polyethylene glycol group)以及氫氧基團(hydroxyl group)所組成之族群。According to another embodiment, the hydrophilic functional group may be a negatively or positively charged functional group, or a polyethylene glycol (PEG) type functional group, and may include at least one selected from a carboxylate group ( carboxylate group, sulfone group, phosphate group, amino group, alkoxy group, ester group, acetate group A group consisting of acetate group, polyethylene glycol group and hydroxyl group.
根據另一實施例，該第一聚合物球體之殼可更具有接於其上之含醣官能基(saccharide-containing functional group)。According to another embodiment, the shell of the first polymer sphere may further have a saccharide-containing functional group attached to it.
根據另一實施例，含醣官能基可衍生自至少一選自由N{N-(3-三乙氧矽基丙基)胺乙基}葡糖醯胺(N-{N-(3-triethoxysilylpropyl)aminoethyl}gluconamide)、N-(3-三乙氧矽基丙基)葡糖醯胺(N-(3-triethoxysilylpropyl) gluconamide)以及N{N-(3-三乙氧矽基丙基)胺乙基}-寡- 玻糖醛酸醯胺。(N-{N-(3-triethoxysilylpropyl)aminoethyl}-oligo-hyaluronamide)組成之族群。According to another embodiment, the sugar-containing functional group can be derived from at least one selected from N{N-(3-triethoxysilylpropyl)aminoethyl}glucamide (N-{N-(3-triethoxysilylpropyl) )aminoethyl)gluconamide), N-(3-triethoxysilylpropyl) gluconamide and N(N-(3-triethoxysilylpropyl) gluconamide) Ethyl}-oligo-hyaluronic acid amide. (N-{N-(3-triethoxysilylpropyl)aminoethyl}-oligo-hyaluronamide) group consisting of.
根據另一實施例，以第一聚合物球體與第二聚合物球體彼此鍵結之接合處為基準，兩親各向異性粉末可具有對稱形狀、不對稱雪人形狀或不對稱反轉雪人形狀。雪人形狀意指第一聚合物球體與第二聚合物球體彼此鍵結且具有不同尺寸。According to another embodiment, the amphiphilic anisotropic powder may have a symmetrical shape, an asymmetrical snowman shape, or an asymmetrically inverted snowman shape based on the junction where the first polymer sphere and the second polymer sphere are bonded to each other. The snowman shape means that the first polymer sphere and the second polymer sphere are bonded to each other and have different sizes.
根據另一實施例，兩親各向異性粉末之顆粒尺寸可為100-2500奈米(nm)。在一變化中，兩親各向異性粉末之顆粒尺寸可為100-1500 nm、100-500 nm或200-300 nm。特別地，兩親性粉末之顆粒尺寸可為100 nm以上、200 nm以上、300 nm以上、400 nm以上、500 nm以上、600 nm以上、700 nm以上、800 nm以上、900 nm以上、1000 nm以上、1100 nm以上、1200 nm以上、1300 nm以上、1400 nm以上、或1500 nm以上；以及2500 nm以下、2400 nm以下、2300 nm以下、2200 nm以下、2100 nm以下、2000 nm以下、 1900 nm以下、1800 nm以下、1700 nm以下、1600 nm以下、1500 nm以下、1400 nm以下、1300 nm以下、1200 nm以下、1100 nm以下、1000 nm以下、900 nm以下、800 nm以下、700 nm以下、600 nm以下、500 nm以下、400 nm以下、300 nm以下、或200 nm以下。According to another embodiment, the particle size of the amphiphilic anisotropic powder may be 100-2500 nanometers (nm). In one variation, the particle size of the amphiphilic anisotropic powder can be 100-1500 nm, 100-500 nm, or 200-300 nm. In particular, the particle size of the amphiphilic powder can be 100 nm or more, 200 nm or more, 300 nm or more, 400 nm or more, 500 nm or more, 600 nm or more, 700 nm or more, 800 nm or more, 900 nm or more, 1000 nm Above, 1100 nm above, 1200 nm above, 1300 nm above, 1400 nm above, or above 1500 nm; and below 2500 nm, below 2400 nm, below 2300 nm, below 2200 nm, below 2100 nm, below 2000 nm, 1900 nm Below, 1800 nm or less, 1700 nm or less, 1600 nm or less, 1500 nm or less, 1400 nm or less, 1300 nm or less, 1200 nm or less, 1100 nm or less, 1000 nm or less, 900 nm or less, 800 nm or less, 700 nm or less, 600 nm or less, 500 nm or less, 400 nm or less, 300 nm or less, or 200 nm or less.
根據另一實施例，兩親各向異性粉末可形成尺寸為2-200微米(μm)之***液顆粒。在一變化中，兩親各向異性粉末可形成尺寸為5-200 μm、10-100 μm、10-50 μm或25 μm之***液顆粒。特別地，兩親各向異性粉末可形成乳液顆粒，其具有尺寸為2 μm以上、5 μm以上、10 μm以上、15 μm以上、20 μm以上、25 μm以上、30 μm以上、40 μm以上、50 μm以上、 80 μm以上、100 μm以上、130 μm以上、150 μm以上、或180 μm以上；以及200 μm以下、180 μm以下、150 μm以下、130 μm以下、100 μm以下、80 μm以下、50 μm以下、40 μm以下、30 μm以下、25 μm以下、20 μm以下、15 μm以下、10 μm以下、或5 μm以下。According to another embodiment, the amphiphilic anisotropic powder can form macroemulsion particles with a size of 2-200 microns (μm). In one variation, the amphiphilic anisotropic powder can form giant emulsion particles with a size of 5-200 μm, 10-100 μm, 10-50 μm, or 25 μm. In particular, the amphiphilic anisotropic powder can form emulsion particles having a size of 2 μm or more, 5 μm or more, 10 μm or more, 15 μm or more, 20 μm or more, 25 μm or more, 30 μm or more, 40 μm or more, 50 μm or more, 80 μm or more, 100 μm or more, 130 μm or more, 150 μm or more, or 180 μm or more; and 200 μm or less, 180 μm or less, 150 μm or less, 130 μm or less, 100 μm or less, 80 μm or less, 50 μm or less, 40 μm or less, 30 μm or less, 25 μm or less, 20 μm or less, 15 μm or less, 10 μm or less, or 5 μm or less.
由於該兩親各向異性粉末之疏水部分及親水部分對於界面具有不同可定向性，而可形成***液顆粒。藉由此類***液顆粒的效能，可能形成具有較低黏性的柔軟使用感。Since the hydrophobic part and the hydrophilic part of the amphiphilic anisotropic powder have different orientability to the interface, macroemulsion particles can be formed. With the effectiveness of such macroemulsion particles, it is possible to form a soft feel with lower viscosity.
當以傳統分子層級界面活性劑形成的界面膜層形成動態乳液相，兩親各向異性粉末形成之乳液顆粒界面膜層厚度增加至數幾百奈米，且憑藉粉末顆粒間強力鍵結效能形成穩固界面膜層。因此，可透過此界面形成來維持穩定乳液狀態。When the interfacial film formed by traditional molecular-level surfactants forms a dynamic emulsion phase, the thickness of the interfacial film of the emulsion particles formed by the amphiphilic anisotropic powder increases to several hundreds of nanometers, and is formed by virtue of the strong bonding between the powder particles. Stabilize the interface film. Therefore, the stable emulsion state can be maintained through the formation of this interface.
根據另一實施例，以該組合物之總重量為基準，兩親各向異性粉末的量可為0.1 wt% 以上、0.2 wt%以上、0.3 wt%以上、0.4 wt%以上、0.5 wt%以上、0.6 wt%以上、0.7 wt%以上、0.8 wt%以上、0.9 wt%以上、1.0 wt%以上、1.5 wt%以上、或2.0 wt%以上；以及20 wt%以下、19 wt%以下、18 wt%以下、17 wt%以下、16 wt%以下、15 wt%以下、14 wt%以下、13 wt%以下、 12 wt%以下、11 wt%以下、10 wt%以下、9 wt%以下、8 wt%以下、7 wt%以下、6 wt%以下、5 wt%以下、4 wt%以下、或3 wt%以下。舉例而言，以該組合物之總重量為基準，兩親各向異性粉末的量可為0.1-10 wt%，特別為 2-6 wt%，且更特別地1-3 wt%。在上述定義範圍內可形成穩定乳液顆粒以及形成具有適當尺寸的乳液顆粒。According to another embodiment, based on the total weight of the composition, the amount of amphiphilic anisotropic powder may be 0.1 wt% or more, 0.2 wt% or more, 0.3 wt% or more, 0.4 wt% or more, 0.5 wt% or more , 0.6 wt% or more, 0.7 wt% or more, 0.8 wt% or more, 0.9 wt% or more, 1.0 wt% or more, 1.5 wt% or more, or 2.0 wt% or more; and 20 wt% or less, 19 wt% or less, 18 wt % Or less, 17 wt% or less, 16 wt% or less, 15 wt% or less, 14 wt% or less, 13 wt% or less, 12 wt% or less, 11 wt% or less, 10 wt% or less, 9 wt% or less, 8 wt % Or less, 7 wt% or less, 6 wt% or less, 5 wt% or less, 4 wt% or less, or 3 wt% or less. For example, based on the total weight of the composition, the amount of amphiphilic anisotropic powder may be 0.1-10 wt%, particularly 2-6 wt%, and more particularly 1-3 wt%. Within the above-defined range, stable emulsion particles can be formed and emulsion particles of appropriate size can be formed.
根據本揭露一實施例，該組成物可包括重量比例為1-9：9-1之矽油與兩親各向異性粉末，特別為1-9：1，且更特別為3：1(矽油：兩親各向異性粉末)。在上述定義範圍內，可形成具有適當尺寸的乳液顆粒且維持穩定乳液狀態。According to an embodiment of the present disclosure, the composition may include silicone oil and amphiphilic anisotropic powder in a weight ratio of 1-9:9-1, particularly 1-9:1, and more particularly 3:1 (silicone oil: Amphipathic anisotropic powder). Within the above-defined range, emulsion particles of appropriate size can be formed and a stable emulsion state can be maintained.
根據另一實施例，油包矽型乳液組成物可更包含皮脂吸收粉末於該油包矽組成物中。According to another embodiment, the silicon-in-oil emulsion composition may further include sebum absorption powder in the silicon-in-oil composition.
特別地，皮脂吸收粉末吸收皮膚分泌的皮脂，且可提供霧面使用感。由於皮脂吸收粉末抑制鑑於傳統油包矽型乳液組成物穩定性而加入之增稠劑增稠功能，使用此類粉末於油包矽型乳液組成物時，需要添加劑以維持增稠狀態，或是需要特殊的處理。不過，因為根據本揭露實施例之水包矽型乳液組成物使用兩親各向異性粉末，且在不增稠情況下維持乳液穩定性，因此乳液配方不會因為此類皮脂吸收粉末存在而受到不利影響。In particular, the sebum absorption powder absorbs sebum secreted by the skin and can provide a matte use feeling. Since the sebum absorption powder inhibits the thickening function of the thickener added in view of the stability of the traditional silicone-in-oil emulsion composition, the use of such powders in the silicone-in-oil emulsion composition requires additives to maintain the thickening state, or Special treatment is required. However, because the silicone-in-water emulsion composition according to the embodiment of the present disclosure uses amphiphilic anisotropic powder and maintains emulsion stability without thickening, the emulsion formula will not be affected by the presence of such sebum absorption powder. Negative Effects.
此皮脂吸收粉末之特定例子包含聚甲基丙烯酸甲酯(polymethyl methacrylate, PMMA)以及二氧化矽(silica)，特別係至少一選自聚甲基丙烯酸甲酯以及二氧化矽。Specific examples of the sebum absorption powder include polymethyl methacrylate (PMMA) and silicon dioxide (silica), especially at least one selected from polymethyl methacrylate and silicon dioxide.
皮脂吸收粉末之平均顆粒直徑可為0.1 μm以上、0.5 μm以上、0.6 μm以上、0.7 μm以上、0.8 μm以上、0.9 μm以上、1.0 μm以上、1.5 μm以上、2.0 μm以上、2.5 μm以上、3.0 μm以上、3.5 μm以上、 4.0 μm以上、或 4.5 μm以上；以及6.5 μm以下、6.0 μm以下、5.5 μm以下、5.0 μm以下、4.5 μm以下、4.0 μm以下、3.5 μm以下、3.0 μm以下、2.5 μm以下、或2.0 μm以下。舉例而言，皮脂吸收粉末之平均顆粒直徑可為0.5-6μm，特別為1μm-5μm。在上述定義範圍內，其可以維持配方穩定性以及霧面定妝感，同時保留明亮使用感。The average particle diameter of the sebum absorption powder can be 0.1 μm or more, 0.5 μm or more, 0.6 μm or more, 0.7 μm or more, 0.8 μm or more, 0.9 μm or more, 1.0 μm or more, 1.5 μm or more, 2.0 μm or more, 2.5 μm or more, 3.0 μm or more, 3.5 μm or more, 4.0 μm or more, or 4.5 μm or more; and 6.5 μm or less, 6.0 μm or less, 5.5 μm or less, 5.0 μm or less, 4.5 μm or less, 4.0 μm or less, 3.5 μm or less, 3.0 μm or less, 2.5 μm or less, or 2.0 μm or less. For example, the average particle diameter of the sebum absorption powder may be 0.5-6 μm, particularly 1 μm-5 μm. Within the above-defined range, it can maintain the stability of the formulation and the matte setting feeling while retaining the bright feeling of use.
以該組成物之總重量為基準，皮脂吸收粉末使用量可為0.1-10重量百分比(wt%)，例如用量為0.5-3wt%。在上述定義範圍內，其可能提供霧面定妝感以及皮脂吸收效果，而同時保留配方穩定性。Based on the total weight of the composition, the amount of sebum absorption powder used can be 0.1-10 weight percent (wt%), for example, the amount is 0.5-3wt%. Within the above-defined range, it may provide a matte finish and sebum absorption effect, while retaining the stability of the formulation.
根據本揭露實施例之包含皮脂吸收粉末之水包矽型乳液組成物可具有黏度為400 cps 以上、500 cps以上、600 cps以上、700 cps以上、800 cps以上、900 cps以上、1000 cps以上、1100 cps以上、1200 cps以上、1300 cps以上、1400 cps以上、1500 cps以上、1600 cps以上、1700 cps以上、1800 cps以上、1900 cps以上、 2000 cps以上、2100 cps以上、2200 cps以上、2300 cps以上、2400 cps以上、或2500 cps以上；以及 4000 cps以下、3900 cps以下、 3800 cps以下、3700 cps以下、3600 cps以下、3500 cps以下、3400 cps以下、3300 cps以下、 3200 cps以下、 3100 cps以下、 3000 cps以下、2900 cps以下、 2800 cps以下、或2700 cps以下。舉例而言，黏度可為500-3000 cps或1000-3000 cps。雖然皮脂吸收粉末阻斷了配方的增稠性，且因此配方顯示出特別低的黏度，此配方維持穩定乳液狀態且提供獨特柔軟性質以及清爽使用感。The silicone-in-water emulsion composition containing sebum absorption powder according to the embodiments of the present disclosure may have a viscosity of 400 cps or more, 500 cps or more, 600 cps or more, 700 cps or more, 800 cps or more, 900 cps or more, 1000 cps or more, 1100 cps or higher, 1200 cps or higher, 1300 cps or higher, 1400 cps or higher, 1500 cps or higher, 1600 cps or higher, 1700 cps or higher, 1800 cps or higher, 1900 cps or higher, 2000 cps or higher, 2100 cps or higher, 2200 cps or higher, 2300 cps Above, 2400 cps or more, or 2500 cps or more; and 4000 cps or less, 3900 cps or less, 3800 cps or less, 3700 cps or less, 3600 cps or less, 3500 cps or less, 3400 cps or less, 3300 cps or less, 3200 cps or less, 3100 cps Below, 3000 cps or less, 2900 cps or less, 2800 cps or less, or 2700 cps or less. For example, the viscosity can be 500-3000 cps or 1000-3000 cps. Although the sebum absorption powder blocks the thickening of the formula, and therefore the formula shows a particularly low viscosity, this formula maintains a stable emulsion state and provides unique softness and a refreshing feeling of use.
根據本揭露實施例之化妝品組成物可藉由一方法獲得，包含製備該兩親各向異性粉末、以及藉由使用該兩親各向異性粉末來乳化油相部分以及水相部分。The cosmetic composition according to the embodiment of the present disclosure can be obtained by a method including preparing the amphiphilic anisotropic powder and emulsifying the oil phase part and the water phase part by using the amphiphilic anisotropic powder.
根據一實施例，兩親各向異性粉末可藉由該方法獲得，包括：聚合一第一單體以獲得一第一聚合物球體之核；塗覆該第一聚合物球體之核以獲得具有核-殼結構之一第一聚合物球體；以及將具有核-殼結構的該第一聚合物球體與第二單體反應以獲得兩親各向異性粉末，其中第二聚合物球體被形成。According to one embodiment, the amphiphilic anisotropic powder can be obtained by the method, including: polymerizing a first monomer to obtain a core of a first polymer sphere; coating the core of the first polymer sphere to obtain a core with A first polymer sphere having a core-shell structure; and reacting the first polymer sphere having a core-shell structure with a second monomer to obtain an amphiphilic anisotropic powder, wherein the second polymer sphere is formed.
圖1為說明根據本揭露一實施例之兩親各向異性粉形成的示意圖。藉由讓第一聚合物球體的核穿透第一聚合物球體之殼，且藉由上述方法朝向外部成長，以形成第二聚合物球體。FIG. 1 is a schematic diagram illustrating the formation of amphiphilic anisotropic powder according to an embodiment of the present disclosure. The second polymer sphere is formed by allowing the core of the first polymer sphere to penetrate the shell of the first polymer sphere and grow toward the outside by the above-mentioned method.
根據另一實施例，製備兩親各向異性粉末之方法可包括：(1)攪拌第一單體與聚合起始劑以形成第一聚合物球體之核；(2)將已形成之第一聚合物球體之核與第一單體、聚合起始劑以及含官能基之單體一起攪拌，以形成具有塗覆的核-殼結構之第一聚合物球體；以及(3)將已形成之具有核-殼結構之第一聚合物球體與第二單體、聚合起始劑一起攪拌以形成各向異性粉末，其中第二聚合物球體被形成。According to another embodiment, the method for preparing the amphiphilic anisotropic powder may include: (1) stirring the first monomer and the polymerization initiator to form the core of the first polymer sphere; (2) combining the first The core of the polymer sphere is stirred together with the first monomer, the polymerization initiator, and the functional group-containing monomer to form the first polymer sphere with a coated core-shell structure; and (3) the already formed The first polymer sphere having a core-shell structure is stirred together with the second monomer and the polymerization initiator to form an anisotropic powder, wherein the second polymer sphere is formed.
在步驟(1)、(2)及(3)中，該攪拌可為旋轉攪拌。因為同相機械式混合必須伴隨著化學修飾以產生均一的顆粒，旋轉攪拌是較佳的。旋轉攪拌可於圓筒狀反應器中執行，但不限於此。In steps (1), (2) and (3), the stirring may be rotary stirring. Because in-phase mechanical mixing must be accompanied by chemical modification to produce uniform particles, rotating stirring is preferable. Rotary stirring can be performed in a cylindrical reactor, but is not limited to this.
在此，反應器的內部設計顯著影響粉末形成。圓筒狀反應器擋板(baffles)的尺寸及位置以及葉輪(impeller)的距離對於所欲製造顆粒的均勻有顯著影響。較佳地，內部擋板以及葉輪葉片的間隔較佳是縮減的，以製造對流且讓其強度均勻，粉狀反應混合器被置入低於擋板長度的位置，且葉輪維持在高旋轉速度。旋轉速度的每分鐘轉數(rpm)可為200 rpm以上，且反應器的直徑與高度的比例可為1-3：1-5。特別地，反應器的直徑可為10-30 公分(cm)且高度為10-50 cm。反應器可隨著反應容量依比例作尺寸變化。此外，圓筒狀反應器可由陶瓷、玻璃等製成。較佳於50-90℃溫度下進行攪拌。Here, the internal design of the reactor significantly affects powder formation. The size and position of the baffles of the cylindrical reactor and the distance of the impeller have a significant effect on the uniformity of the particles to be produced. Preferably, the interval between the internal baffle and the impeller blades is preferably reduced to create convection and make its strength uniform. The powdered reaction mixer is placed below the length of the baffle, and the impeller is maintained at a high rotation speed. . The number of revolutions per minute (rpm) of the rotation speed can be 200 rpm or more, and the ratio of the diameter to the height of the reactor can be 1-3:1-5. In particular, the diameter of the reactor may be 10-30 centimeters (cm) and the height of 10-50 cm. The size of the reactor can be changed in proportion to the reaction capacity. In addition, the cylindrical reactor can be made of ceramics, glass, or the like. Stirring is preferably performed at a temperature of 50-90°C.
圓筒狀旋轉反應器的簡易混合能夠產生均勻的顆粒，所需能源損耗低，且提供極大化的反應效率，因此適合大量製造。傳統翻滾法包含反應器本身的旋轉，造成反應器整體部分有特定角度的斜角，且於高速下旋轉，因此所需能源損耗高且限制了反應器尺寸。因為反應器尺寸的限制，產出被限制至很小的量大約數十毫克至數克的。因此，傳統翻滾法不適合大量製造。The simple mixing of the cylindrical rotating reactor can produce uniform particles, requires low energy consumption, and provides maximum reaction efficiency, so it is suitable for mass production. The traditional tumbling method involves the rotation of the reactor itself, which causes the whole part of the reactor to have a specific angle of oblique angle and rotate at a high speed. Therefore, the required energy consumption is high and the reactor size is limited. Due to the size of the reactor, the output is limited to a very small amount of about tens of milligrams to several grams. Therefore, the traditional tumbling method is not suitable for mass manufacturing.
根據一實施例，第一單體與第二單體可為相同或不同，且較佳為乙烯基單體。此外，步驟(2)中添加的第一單體可與步驟(1)使用的第一單體相同，每一步驟中所使用的聚合起始劑可為相同或不同。According to an embodiment, the first monomer and the second monomer may be the same or different, and are preferably vinyl monomers. In addition, the first monomer added in step (2) may be the same as the first monomer used in step (1), and the polymerization initiator used in each step may be the same or different.
根據另一實施例，乙烯基單體可為乙烯基芳香單體(vinyl aromatic monomer)。乙烯基芳香單體可為經取代或未經取代的苯乙烯。According to another embodiment, the vinyl monomer may be a vinyl aromatic monomer. The vinyl aromatic monomer can be substituted or unsubstituted styrene.
根據另一實施例，聚合起始劑可為自由基聚合起始劑。特別地，聚合起始劑可為過氧化型(peroxide-based)或偶氮型(azo-based)起始劑，或是其結合。此外，也可使用過硫酸銨(ammonium persulfate)、過硫酸鈉(sodium persulfate)或過硫酸鉀(potassium persulfate)。According to another embodiment, the polymerization initiator may be a radical polymerization initiator. In particular, the polymerization initiator may be a peroxide-based or azo-based initiator, or a combination thereof. In addition, ammonium persulfate, sodium persulfate, or potassium persulfate can also be used.
根據另一實施例，在步驟(1)中，第一單體與聚合起始劑混合的重量比例可為100-1000：1。在一變化中，第一單體與聚合起始劑混合的重量比例可為100-750：1、100-500：1或100-250：1。According to another embodiment, in step (1), the mixing weight ratio of the first monomer and the polymerization initiator may be 100-1000:1. In a variation, the mixing weight ratio of the first monomer and the polymerization initiator may be 100-750:1, 100-500:1, or 100-250:1.
在一變化中，在步驟(1)中，可將穩定劑以第一單體、聚合起始劑及穩定劑混合重量比例為100-1000：1：0.001-5的方式，一起加入第一單體及聚合起始劑中。粉末的尺寸及形狀係是控制步驟(1)中的第一聚合物球體尺寸來決定，且第一聚合物球體的尺寸可由第一單體、聚合起始劑以及穩定劑的比例來控制。此外，由於上述定義比例內混合第一單體、聚合起始劑以及穩定劑，可增加各向異性粉末的均勻度。In a variation, in step (1), the stabilizer can be added to the first monomer together with the first monomer, polymerization initiator and stabilizer in a mixing weight ratio of 100-1000:1:0.001-5. Body and polymerization initiator. The size and shape of the powder are determined by controlling the size of the first polymer sphere in step (1), and the size of the first polymer sphere can be controlled by the ratio of the first monomer, polymerization initiator and stabilizer. In addition, since the first monomer, polymerization initiator, and stabilizer are mixed in the above-defined ratio, the uniformity of the anisotropic powder can be increased.
根據一實施例，穩定劑可以是離子型乙烯基單體，且特別可使用4-乙烯基苯磺酸鈉(sodium 4-vinylbenzene sulfonate)。穩定劑防止顆粒膨脹，且導入正電或負電荷至粉末表面，因此防止了靜電顆粒聚結(連結)。According to an embodiment, the stabilizer may be an ionic vinyl monomer, and particularly sodium 4-vinylbenzene sulfonate (sodium 4-vinylbenzene sulfonate) may be used. The stabilizer prevents the particles from swelling and introduces positive or negative charges to the surface of the powder, thus preventing the agglomeration (connection) of the electrostatic particles.
當兩親各向異性粉末尺寸為200-250 nm，其可由第一聚合物球體獲得，包含第一單體、聚合起始劑及穩定劑比例為110-130：1：2-4，特別為115-125：1：2-4。When the size of the amphiphilic anisotropic powder is 200-250 nm, it can be obtained from the first polymer sphere, and the ratio of the first monomer, polymerization initiator and stabilizer is 110-130:1:2-4, especially 115-125: 1:2-4.
此外，當兩親各向異性粉末尺寸為400-450 nm，其可由第一聚合物球體獲得，包含第一單體、聚合起始劑及穩定劑比例為225-240：1：1-3，特別為230-235：1：1-3。In addition, when the size of the amphiphilic anisotropic powder is 400-450 nm, it can be obtained from the first polymer sphere, and the ratio of the first monomer, polymerization initiator and stabilizer is 225-240:1:1-3, Especially 230-235:1:1-3.
此外，當兩親各向異性粉末尺寸為1100-2500 nm，其可由第一聚合物球體獲得，透過將第一單體、聚合起始劑及穩定劑以比例為110-130：1：0反應製備而成，特別為115-125：1：0。In addition, when the size of the amphiphilic anisotropic powder is 1100-2500 nm, it can be obtained from the first polymer sphere by reacting the first monomer, polymerization initiator and stabilizer in a ratio of 110-130:1:0 Prepared, especially 115-125:1:0.
此外，具有不對稱雪人形狀的兩親各向異性粉末，其可由第一聚合物球體獲得，透過將第一單體、聚合起始劑及穩定劑以比例為100-140：1：8-12反應製備而成，特別為110-130：1：9-11。In addition, the amphiphilic anisotropic powder with an asymmetric snowman shape can be obtained from the first polymer sphere by combining the first monomer, polymerization initiator and stabilizer in a ratio of 100-140:1:8-12 Prepared by reaction, especially 110-130:1:9-11.
此外，具有不對稱反轉雪人形狀的兩親各向異性粉末，其可由第一聚合物球體獲得，透過將第一單體、聚合起始劑及穩定劑以比例為100-140：1：1-5反應製備而成，特別為110-130：1：2-4。In addition, the amphiphilic anisotropic powder with an asymmetric inverted snowman shape can be obtained from the first polymer sphere by combining the first monomer, polymerization initiator and stabilizer in a ratio of 100-140:1:1 -5 prepared by reaction, especially 110-130:1:2-4.
根據另一實施例，在步驟(2)之含官能基單體可為含矽氧烷(甲基)丙烯酸酯(siloxane-containing (meth)acrylate)，例如3-(三甲氧基矽烷基)丙基丙烯酸酯(3-(trimethoxysilyl)propyl acrylate)、3-(三甲氧基矽烷基)丙基甲基丙烯酸酯(3-(trimethoxysilyl)propyl methacrylate)、乙烯基三乙氧基矽烷(vinyl triethoxysilane)、乙烯基三甲氧基矽烷(vinyl trimethoxysilane)或上述之結合。According to another embodiment, the functional group-containing monomer in step (2) may be a siloxane-containing (meth)acrylate, such as 3-(trimethoxysilyl) acrylate. 3-(trimethoxysilyl)propyl acrylate, 3-(trimethoxysilyl)propyl methacrylate, vinyl triethoxysilane, Vinyl trimethoxysilane or a combination of the above.
根據另一實施例，在步驟(2)中，第一單體、聚合起始劑以及含官能基化合物可依重量比例為80-98：0.2-1.0：1-20混合。在一變化中，第一單體、聚合起始劑以及含官能基化合物可依重量比例為160-200：1：6-40混合。可依照反應比例控制塗覆程度，且塗覆程度決定兩親各向異性粉末之形狀。以起始厚度為基準，當第一單體、聚合起始劑以及含官能基化合物依上述定義比例內使用時，塗覆厚度增加約10-30%，特別地大約為20%。在此案例中，粉末順利形成而沒有下列問題，例如過厚的塗覆造成粉末無法形成、或過薄的塗覆造成粉末多向性形成。此外，在上述重量比例內可以增加各向異性粉末的均勻度。According to another embodiment, in step (2), the first monomer, the polymerization initiator, and the functional group-containing compound may be mixed in a weight ratio of 80-98:0.2-1.0:1-20. In a variation, the first monomer, polymerization initiator, and functional group-containing compound can be mixed in a weight ratio of 160-200:1:6-40. The coating degree can be controlled according to the reaction ratio, and the coating degree determines the shape of the amphiphilic anisotropic powder. Based on the initial thickness, when the first monomer, polymerization initiator, and functional group-containing compound are used in the above-defined ratio, the coating thickness increases by about 10-30%, especially about 20%. In this case, the powder was formed smoothly without the following problems, for example, too thick coating caused the powder to be unable to form, or too thin coating caused the powder to form multi-directionally. In addition, the uniformity of the anisotropic powder can be increased within the above-mentioned weight ratio.
在步驟(3)，第一聚合物球體的核從該具有核-殼結構之第一聚合物球體的方向穿透經過殼體，且從該殼體向外凸出。然後，此凸起可透過第二單體的聚合物來增大，以形成各向異性粉末形狀。In step (3), the core of the first polymer sphere penetrates through the shell from the direction of the first polymer sphere with the core-shell structure, and protrudes outward from the shell. Then, the protrusion can be enlarged through the polymer of the second monomer to form an anisotropic powder shape.
根據另一實施例，在步驟(3)中，第二單體與聚合起始劑可依重量比例為150-250：1來混合。在一變化例，第二單體與聚合起始劑的混合重量比例可為160-250：1、170-250：1、180-250：1、190-250：1、200-250：1、210-250：1、220-250： 1、230-250：1、或240-250：1。According to another embodiment, in step (3), the second monomer and the polymerization initiator can be mixed in a weight ratio of 150-250:1. In a modified example, the mixing weight ratio of the second monomer and the polymerization initiator can be 160-250:1, 170-250:1, 180-250:1, 190-250:1, 200-250:1, 210-250:1, 220-250:1, 230-250:1, or 240-250:1.
在一變化中，在步驟(3)中，可將穩定劑以第二單體、聚合起始劑及穩定劑混合重量比例為150-250：1：0.001-5的方式，一起加入第二單體及聚合起始劑中。穩定劑之特定例子與上述相同。在上述重量比例內，可增加各向異性粉末之均勻度。In a variation, in step (3), the stabilizer can be added to the second monomer together with the second monomer, polymerization initiator and stabilizer in a mixing weight ratio of 150-250:1:0.001-5. Body and polymerization initiator. The specific examples of the stabilizer are the same as described above. Within the above weight ratio, the uniformity of the anisotropic powder can be increased.
根據另一實施例，在步驟(3)中，以具有核-殼結構之第一聚合物球體重量為100重量份，第二單體的混合重量約為40-300重量份。特別地，以該第一聚合物球體為100重量份為基底，當該第二單體的含量為40-100重量份%時，得到非對稱雪人狀粉末。當該第二單體的含量為100-150重量份或110-150重量份時，得到對稱粉末。此外，當該第二單體的含量為150-300重量份或160-300重量份時，得到非對稱反轉雪人狀粉末。在上述重量比例內可增加各向異性粉末之均勻度。According to another embodiment, in step (3), the weight of the first polymer sphere having the core-shell structure is 100 parts by weight, and the mixing weight of the second monomer is about 40-300 parts by weight. In particular, when the first polymer sphere is 100 parts by weight as a base, when the content of the second monomer is 40-100 parts by weight, an asymmetric snowman-like powder is obtained. When the content of the second monomer is 100-150 parts by weight or 110-150 parts by weight, a symmetrical powder is obtained. In addition, when the content of the second monomer is 150-300 parts by weight or 160-300 parts by weight, an asymmetric inverted snowman-like powder is obtained. The uniformity of the anisotropic powder can be increased within the above-mentioned weight ratio.
根據另一實施例，製備兩親各向異性粉末的方法可在步驟(3)後，更包括步驟(4)，將親水性官能基接入該各向異性粉末。According to another embodiment, the method for preparing amphiphilic anisotropic powder may further include step (4) after step (3), to connect hydrophilic functional groups to the anisotropic powder.
根據另一實施例，步驟(4)的親水性官能基可透過使用矽烷耦合劑(silane coupling agent)以及反應修飾劑(reaction modifier)來接入，但不限於此。According to another embodiment, the hydrophilic functional group in step (4) can be accessed by using a silane coupling agent and a reaction modifier, but it is not limited thereto.
根據另一實施例，矽烷耦合劑可至少一選自由N - [(3-(三甲氧基矽烷基)丙基)乙二胺(N-[(3-(trimethoxysilyl)propyl)ethylenediamine)、N - [3-(三甲氧基矽烷基)丙基)乙烯氯化銨(N-[3-(trimethoxysilyl)propyl]ethylene diammonium chloride)、(N-琥珀醯基-3-氨基丙基)三乙氧基矽烷((N-succinyl-3-aminopropyl)trimethoxysilane)、1-[3-(三甲氧基矽烷基)丙基]尿素(1-[3-(trimethoxysilyl)propyl]urea)以及3-[(三甲氧基矽烷基)丙氧基]-1,2-丙二醇 (3-[(trimethoxysilyl)propyloxy]-1,2-propanediol)組成之族群。特別地，該矽烷耦合劑可為N - [(3-(三甲氧基矽烷基)丙基)乙二胺。According to another embodiment, the silane coupling agent may be at least one selected from N-[(3-(trimethoxysilyl)propyl)ethylenediamine (N-[(3-(trimethoxysilyl)propyl)ethylenediamine), N- [3-(trimethoxysilyl) propyl) ethylene ammonium chloride (N-[3-(trimethoxysilyl)propyl]ethylene diammonium chloride), (N-succinyl-3-aminopropyl) triethoxy Silane ((N-succinyl-3-aminopropyl)trimethoxysilane), 1-[3-(trimethoxysilyl)propyl]urea (1-[3-(trimethoxysilyl)propyl]urea) and 3-[(trimethoxysilyl) Trimethoxysilyl)propoxy]-1,2-propanediol (3-[(trimethoxysilyl)propyloxy]-1,2-propanediol). In particular, the silane coupling agent may be N-[(3-(trimethoxysilyl)propyl)ethylenediamine.
根據另一實施例，以步驟(3)獲得之各向異性粉末為100重量份為基準，矽烷耦合劑的混合量可為35-65重量份，特別是40-60重量份。在上述定義範圍內可以適當地實現親水化(hydrophilization)。According to another embodiment, based on 100 parts by weight of the anisotropic powder obtained in step (3), the mixing amount of the silane coupling agent may be 35-65 parts by weight, especially 40-60 parts by weight. Hydrophilization can be appropriately achieved within the above-defined range.
根據另一實施例，反應修飾劑可以是氫氧化銨(ammonium hydroxide)。According to another embodiment, the reaction modifier may be ammonium hydroxide.
根據另一實施例，以步驟(3)獲得之各向異性粉末為100重量份為基準，反應修飾劑的混合量可為85-115重量份，特別是90-110重量份。在上述定義範圍內可以適當地實現親水化(hydrophilization)。According to another embodiment, based on 100 parts by weight of the anisotropic powder obtained in step (3), the mixing amount of the reaction modifier may be 85-115 parts by weight, especially 90-110 parts by weight. Hydrophilization can be appropriately achieved within the above-defined range.
根據另一實施例，製備兩親各向異性粉末的方法可在步驟(3)後，更包括步驟(4)，將含醣官能基(saccharide-containing functional group)接入該各向異性粉末。According to another embodiment, the method for preparing an amphiphilic anisotropic powder may further include step (4) after step (3), incorporating a saccharide-containing functional group into the anisotropic powder.
在步驟(4)中，可藉由含醣矽烷耦合劑以及反應修飾劑將含醣官能基接入，但不限於此。In step (4), the sugar-containing functional group can be connected by the sugar-containing silane coupling agent and the reaction modifier, but it is not limited to this.
根據另一實施例，含醣矽烷耦合劑可至少一選自由N{N-(3-三乙氧矽基丙基)胺乙基}葡糖醯胺、N-(3-三乙氧矽基丙基)葡糖醯胺以及N{N-(3-三乙氧矽基丙基)胺乙基}-寡- 玻糖醛酸醯胺組成之族群。According to another embodiment, the sugar-containing silane coupling agent can be at least one selected from N{N-(3-triethoxysilylpropyl)aminoethyl}glucamide, N-(3-triethoxysilyl Propyl) glucamide and N{N-(3-triethoxysilylpropyl)aminoethyl}-oligo-hyaluronic acid amide group.
根據另一實施例，反應修飾劑可為氫氧化銨。According to another embodiment, the reaction modifier may be ammonium hydroxide.
根據另一實施例，以步驟(3)獲得之各向異性粉末為100重量份為基準，反應修飾劑的混合量可為85-115重量份，特別是90-110重量份。在上述定義範圍內可以適當地將含醣官能基接入。According to another embodiment, based on 100 parts by weight of the anisotropic powder obtained in step (3), the mixing amount of the reaction modifier may be 85-115 parts by weight, especially 90-110 parts by weight. The sugar-containing functional group can be appropriately added within the above-defined range.
本文揭露之兩親各向異性粉末的製備方法不需使用交聯劑，因此不會導致結塊(agglomeration)，且提供了高產率及均勻度。此外，本文揭露之方法使用簡易的攪拌製程，因此相較於翻滾製程(tumbling process)更易於大量製造。特別地，本文揭露之方法是相當良好的，因此其能夠大規模生產數十克至數十公斤之尺寸為300 nm以下之奈米尺寸顆粒。The preparation method of the amphiphilic anisotropic powder disclosed herein does not require the use of a cross-linking agent, so it does not cause agglomeration, and provides high yield and uniformity. In addition, the method disclosed in this article uses a simple mixing process, so it is easier to mass manufacture than a tumbling process. In particular, the method disclosed in this article is quite good, so it can mass-produce nano-sized particles of tens of grams to tens of kilograms with a size of 300 nm or less.
根據本揭露實施例之組成物可更包含增稠劑以提供適當地黏度。該增稠劑可以是妝品領域中傳統化使用的增稠劑。The composition according to the embodiment of the present disclosure may further include a thickener to provide an appropriate viscosity. The thickener may be a thickener traditionally used in the cosmetics field.
根據本揭露實施例之組成物具有油包矽型乳液配方，且因此提供不黏膩的清爽使用感。The composition according to the embodiment of the present disclosure has a silicone-in-oil emulsion formula, and therefore provides a non-sticky, refreshing feeling of use.
根據本揭露一實施例之組成物在不使用界面活性劑情況下，於乳液配方中具有優異乳液穩定性，且提供了乳液組成物之柔軟使用感結合來自矽油的絲綢及霧面定妝感。特別地，組成物提供上述效果，其中該化妝品組成物的穩定性不因皮脂吸收粉末的存在而受到影響。The composition according to an embodiment of the present disclosure has excellent emulsion stability in the emulsion formulation without using a surfactant, and provides the soft use feeling of the emulsion composition combined with the silk and matte makeup feel from the silicone oil. In particular, the composition provides the above-mentioned effects, wherein the stability of the cosmetic composition is not affected by the presence of sebum absorption powder.
根據本揭露實施例之組成物在寬廣溫度範圍內隨著時間的推移顯示出乳液穩定性。The composition according to the embodiment of the present disclosure exhibits emulsion stability over time in a wide temperature range.
根據本揭露實施例之組成物包含***液顆粒以提供柔軟及絲綢使用感。The composition according to the embodiment of the present disclosure contains macroemulsion particles to provide softness and silky feel.
根據本揭露實施例之組成物可穩定水包矽型乳液組成物，以提供具有不黏膩明亮使用感以及絲綢霧面定妝感的可流動性配方。The composition according to the embodiment of the present disclosure can stabilize the silicone-in-water emulsion composition to provide a flowable formula with a non-sticky, bright use feeling and a silky matte finish feeling.
根據本揭露實施例之組成物的配製可以摻入化妝品級或皮膚學可接受之介質或基底於其中。此配方包含因應局部應用的任意調配，且可以懸浮液(suspension)、微乳液(microemulsion)、微膠囊(microcapsules)、微顆粒(microgranules)或離子性(脂質體(liposome))及非離子性多孔狀分散劑(vesicular dispersant) 的形態提供，或是以乳膏(cream)、潤膚品(skin)、洗劑(lotion)、粉末(powder)、軟膏(ointment)、噴霧(spray)或遮瑕棒(conceal stick)的形態提供。此外，該組成物可以泡沫形態使用或是包含加壓推進劑(pressurized propellant)的氣膠(aerosol)組成物。此類組合物可以通過本領域技術人員已知的方法獲得。The formulation of the composition according to the embodiment of the present disclosure can be incorporated into a cosmetic-grade or dermatologically acceptable medium or substrate. This formula contains any formulation for topical application, and can be suspension, microemulsion, microcapsules, microgranules or ionic (liposome) and non-ionic porous Available in the form of vesicular dispersant, or as cream, skin, lotion, powder, ointment, spray or concealer stick Provided in the form of (conceal stick). In addition, the composition can be used in the form of a foam or an aerosol composition containing a pressurized propellant. Such compositions can be obtained by methods known to those skilled in the art.
根據本揭露實施例之組成物可包含傳統使用於化妝品或皮膚學領域的補充材料，例如粉末、油脂材料(fat materal)、有機溶劑(、溶解劑(solubilizer)、濃縮劑(concentrating agent)、膠化劑(gelling agent)、軟化劑(softening agent)、抗氧化劑、懸浮劑(suspending agent)、穩定劑、起泡劑(foaming agent)、香化劑(perfuming agent)、界面活性劑、水、離子型或非離子型乳化劑、填充劑、金屬離子螫合劑、螫合劑、防腐劑、維生素、保護劑、潤濕劑、精華油(essential oil)、染料、顏料、親水性或親油性活化劑、脂質囊泡(lipid vesicles)或任何其他傳統用於化妝品的材料。這些補充材料依照一般於化妝品或皮膚學領域中的使用量加入。根據本揭露實施例之組成物可更包含皮膚吸收增進劑以增加改良皮膚狀況的效果。 [發明模式]The composition according to the embodiments of the present disclosure may include supplementary materials traditionally used in cosmetics or dermatology, such as powders, fat materals, organic solvents, solubilizers, concentrating agents, and glues. Gelling agent, softening agent, antioxidant, suspending agent, stabilizer, foaming agent, perfuming agent, surfactant, water, ion Type or non-ionic emulsifiers, fillers, metal ion chelating agents, chelating agents, preservatives, vitamins, protective agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic activators, Lipid vesicles or any other materials traditionally used in cosmetics. These supplementary materials are added in accordance with the amounts generally used in the field of cosmetics or dermatology. The composition according to the embodiments of the present disclosure may further include a skin absorption enhancer. Increase the effect of improving skin conditions. [Invention Mode]
現將描述實例以詳細說明本揭露。此領域具有通常知識者將理解下列實例僅為示例性目的且非用以意圖限制本揭露之範圍。 [製備實例1-4]Examples will now be described to illustrate the disclosure in detail. Those with ordinary knowledge in the field will understand that the following examples are for illustrative purposes only and are not intended to limit the scope of the present disclosure. [Preparation Example 1-4]
根據下表1之組成得到製備實例1-4。製備方法將於後文中解釋。According to the composition of Table 1 below, Preparation Examples 1-4 were obtained. The preparation method will be explained later.
製備實例1-4使用之材料如下所示。 [表1]
製備實例 1 。製備聚苯乙烯 (PS) 第一聚合物球體。 首先，將作為單體之50g苯乙烯、作為穩定劑之1.0g的4-乙烯基苯磺酸鈉(sodium 4-vinylbenzene sulfonate)以及作為聚合起始劑之0.5g偶氮雙異丁腈(AIBN)混合於水相中，且於75℃下反應8小時。反應的進行，是於玻璃製備之直徑為11cm高度為17cm之圓筒狀反應器中於200rpm的速度下攪拌該反應混合物。 Preparation Example 1 . Prepare polystyrene (PS) first polymer spheres. First, 50g of styrene as a monomer, 1.0g of sodium 4-vinylbenzene sulfonate as a stabilizer, and 0.5g of azobisisobutyronitrile (AIBN) as a polymerization initiator ) Mix in the water phase and react at 75°C for 8 hours. The reaction was carried out by stirring the reaction mixture at a speed of 200 rpm in a cylindrical reactor with a diameter of 11 cm and a height of 17 cm for glass preparation.
製備實例2。製備具有核-殼(CS)結構之已塗覆第一聚合物球體。Preparation Example 2. A first polymer sphere coated with a core-shell (CS) structure is prepared.
首先，將300g之上述獲得的聚苯乙烯(PS)第一聚合物球體顆粒，與作為單體之50g苯乙烯、6g的三甲氧基矽烷基丙基丙烯酸酯(TMSPA)、以及作為聚合起始劑之0.2g偶氮雙異丁腈(AIBN)混合，且該反應混合物於75℃下反應8小時。藉由於圓筒狀反應器中攪拌該反應混合物進行反應。 First, 300g of the polystyrene (PS) first polymer sphere particles obtained above, 50g of styrene as a monomer, 6g of trimethoxysilylpropyl acrylate (TMSPA), and as a polymerization start 0.2g of azobisisobutyronitrile (AIBN) was mixed, and the reaction mixture was reacted at 75°C for 8 hours. The reaction is carried out by stirring the reaction mixture in a cylindrical reactor.
製備實例3。製備兩親各向異性粉末(DB)。Preparation Example 3. Prepare amphiphilic anisotropic powder (DB).
首先，將240g之上述獲得的聚苯乙烯-核殼(PS-CS)分散劑之水相分散劑，與作為單體之40g苯乙烯、作為穩定劑之0.35g的4-乙烯基苯磺酸鈉、以及作為聚合起始劑之0.2g偶氮雙異丁腈(AIBN)混合，且該反應混合物加熱至75℃進行反應8小時。藉由於圓筒狀反應器中攪拌該反應混合物進行反應。在此方法中，獲得兩親各向異性粉末。 First, 240g of the polystyrene-core-shell (PS-CS) water phase dispersant obtained above was mixed with 40g of styrene as a monomer and 0.35g of 4-vinylbenzenesulfonic acid as a stabilizer. Sodium and 0.2 g of azobisisobutyronitrile (AIBN) as a polymerization initiator were mixed, and the reaction mixture was heated to 75° C. and reacted for 8 hours. The reaction is carried out by stirring the reaction mixture in a cylindrical reactor. In this method, amphiphilic anisotropic powder is obtained.
製備實例4，製備親水化兩親各向異性粉末。Preparation Example 4, preparation of hydrophilized amphiphilic anisotropic powder.
首先，將600g上述獲得的各向異性粉末之水相分散劑，與作為矽烷耦合劑之30g的N-[(3-(三甲氧基矽烷基)丙基)乙二胺、以及作為反應修飾劑之60g的氫氧化銨混合，該反應混合物於25℃下反應24小時，以接入親水性官能基。藉由於圓筒狀反應器中攪拌該反應混合物進行反應，以獲得親水化兩親各向異性粉末。 First, 600g of the aqueous phase dispersant of the anisotropic powder obtained above, and 30g of N-[(3-(trimethoxysilyl)propyl)ethylenediamine as a silane coupling agent, and as a reaction modifier 60g of ammonium hydroxide was mixed, and the reaction mixture was reacted at 25°C for 24 hours to access hydrophilic functional groups. The reaction is carried out by stirring the reaction mixture in a cylindrical reactor to obtain hydrophilized amphiphilic anisotropic powder.
下列實例及比較例使用之材料顯示於下。The materials used in the following examples and comparative examples are shown below.
(a)水分散式兩親各向異性粉末：將10wt%之製備實例3的兩親各向異性粉末溶解於55wt%純水以及35wt%丁二醇中獲得溶液。 (b)界面活性劑：甘油硬脂酸酯(Glyceryl stearate)/PEG-100 硬脂酸鹽(Arlacel 170-PA-(SG)，Uniquema)。 (c)矽油：十甲基環五矽氧烷 (DC345，Dow Corning)。 (d)保濕劑： 1,3-丁二醇(Daicel) 甘油(Glycerin)( PALM-OLEO) (e)防腐劑：苯氧乙醇(Clariant) (f)軟化劑(Emollient)：乙基己基甘油(Ethylhexylglycerin) (Sensiva SC50，Schülke & Mayr) (g)中和劑：胺丁三醇(Tromethamine) (Tris amino ultra PC，Dow Chemicals) (h)增稠劑：聚丙烯酸酯聚合物(Flogel 700, SNF S.A.) (i)皮脂吸收粉末：二氧化矽(Silnos 3m，NanoTech，平均顆粒直徑3 μm)[ 實例 1 及比較例 1] 製備水包矽型組成物 (a) Water-dispersed amphiphilic anisotropic powder: 10wt% of the amphiphilic anisotropic powder of Preparation Example 3 was dissolved in 55wt% pure water and 35wt% butanediol to obtain a solution. (b) Surfactant: Glyceryl stearate/PEG-100 stearate (Arlacel 170-PA-(SG), Uniquema). (c) Silicone oil: Decamethylcyclopentasiloxane (DC345, Dow Corning). (d) Humectant: 1,3-Butanediol (Daicel) Glycerin (PALM-OLEO) (e) Preservative: Phenoxyethanol (Clariant) (f) Softener (Emollient): Ethylhexylglycerol (Ethylhexylglycerin) (Sensiva SC50, Schülke & Mayr) (g) Neutralizer: Tromethamine (Tris amino ultra PC, Dow Chemicals) (h) Thickener: polyacrylate polymer (Flogel 700, SNF SA) (i) Sebum absorption powder: Silicon dioxide (Silnos 3m, NanoTech, average particle diameter 3 μm) [ Example 1 and Comparative Example 1] Preparation of silicon-in-water composition
實例1與比較例1之水包矽型乳液組成物根據下表2的組成製備。實例1是使用根據製備實例3所製備之兩親各向異性粉末所得到的乳液組成物，且比較例1是使用傳統界面活性劑的乳液組成物。The silicon-in-water emulsion compositions of Example 1 and Comparative Example 1 were prepared according to the composition of Table 2 below. Example 1 is an emulsion composition obtained by using the amphiphilic anisotropic powder prepared according to Preparation Example 3, and Comparative Example 1 is an emulsion composition using a traditional surfactant.
[測試實例1]以時間評估乳液穩定性[Test Example 1] Evaluate emulsion stability with time
實例1及比較例1之組成物維持在30℃下持續4週，以測定乳液顆粒的乳液穩定性。結果顯示於圖2。 The compositions of Example 1 and Comparative Example 1 were maintained at 30° C. for 4 weeks to determine the emulsion stability of the emulsion particles. The results are shown in Figure 2.
從圖2的結果看出，儘管實例1具有低黏度配方，其還是形成S/W***液顆粒，而且在4週後仍穩定維持乳液顆粒。相對地，比較例1的組成物包含小的乳液顆粒且具有高黏度而提供了不佳使用感。此外，比較例1之組成物維持穩定性4週，但4週後黏度改變，如同下列黏度評估所測定，且因此無法確定有足夠的穩定性。 It can be seen from the results in Fig. 2 that although Example 1 has a low-viscosity formulation, it still forms S/W macroemulsion particles, and still maintains the emulsion particles stably after 4 weeks. In contrast, the composition of Comparative Example 1 contains small emulsion particles and has a high viscosity, which provides a poor sense of use. In addition, the composition of Comparative Example 1 maintained stability for 4 weeks, but the viscosity changed after 4 weeks, as determined by the following viscosity evaluation, and therefore, sufficient stability could not be confirmed.
[實例2以及比較例2]製備包含皮脂吸收粉末的組成物[Example 2 and Comparative Example 2] Preparation of composition containing sebum absorption powder
實例2及比較例2之水包矽型乳液組成物根據下表3組成製備。 The silicon-in-water emulsion compositions of Example 2 and Comparative Example 2 were prepared according to the composition of Table 3 below.
[[ 測試實例Test case 2]2] 依據皮脂吸收粉末的存在評估乳液穩定性Evaluate emulsion stability based on the presence of sebum absorption powder
實例2與比較例2之組成物維持在30℃下持續4週，以測定乳液顆粒的乳液穩定性。結果顯示於圖3。The compositions of Example 2 and Comparative Example 2 were maintained at 30°C for 4 weeks to determine the emulsion stability of the emulsion particles. The results are shown in Figure 3.
從圖3的結果看出，儘管實例2的增稠系統因為二氧化矽粉末存在而瓦解，實例2仍維持乳液穩定性以及低黏度長達4週。相對地，比較例2因為二氧化矽粉末而顯示出不穩定的乳液狀態，導致乳液顆粒尺寸增加。再者，比較例2在4週後造成乳液顆粒的結塊，導致乳液系統完全瓦解。[ 測試實例 3] 以溫度評估配方穩定性 It can be seen from the results in Fig. 3 that although the thickening system of Example 2 collapsed due to the presence of silica powder, Example 2 still maintained emulsion stability and low viscosity for up to 4 weeks. In contrast, Comparative Example 2 showed an unstable emulsion state due to the silica powder, resulting in an increase in the size of the emulsion particles. Furthermore, Comparative Example 2 caused the agglomeration of the emulsion particles after 4 weeks, resulting in the complete breakdown of the emulsion system. [ Test Example 3] Evaluate the stability of the formulation by temperature
實例1、2以及比較例1、2的組成物維持於60℃下持續3天，並且觀察每一組成物的外觀。每一組成物存放3天後的照相圖片顯示於圖4。The compositions of Examples 1 and 2 and Comparative Examples 1 and 2 were maintained at 60°C for 3 days, and the appearance of each composition was observed. The photographic pictures of each composition after storage for 3 days are shown in Fig. 4.
當組成物存放於60℃下3天後，實例1及2皆維持清楚的外觀，且乳液狀態維持穩定。相對地，比較例2產生乳液顆粒結塊且完全相分離。[ 測試實例 4] 黏度改變評估 After the composition was stored at 60°C for 3 days, both Examples 1 and 2 maintained a clear appearance, and the emulsion state remained stable. In contrast, Comparative Example 2 resulted in agglomeration of emulsion particles and complete phase separation. [ Test Example 4] Viscosity change evaluation
根據實例1及2以及比較例1及2之每一組成物黏度隨著時間使用黏度計(LVDV-II+PRO，BROOKFIELD，USA)測量，其維持於30℃下持續14週。結果顯示於下表4。 [表 4]
從表4的結果看出，每個實例1及2形成低黏度配方且維持其黏度超過14週。相反地，比較例1呈現相當高黏度且產生黏度變化。比較例2隨著時間呈現相當大的變化，於1週後產生相分離，且其乳液狀態歷經瓦解，因而無法測定其黏度。[ 測試實例 4] 感官品評 It can be seen from the results in Table 4 that each of Examples 1 and 2 formed a low-viscosity formulation and maintained its viscosity for more than 14 weeks. In contrast, Comparative Example 1 exhibited a relatively high viscosity and produced a viscosity change. Comparative Example 2 showed a considerable change over time, phase separation occurred after 1 week, and its emulsion state had undergone disintegration, so its viscosity could not be measured. [ Test Example 4] Sensory Evaluation
30位20歲至40歲之男性審議員被允許使用來自比較例1及2以及實例1及2的每一化妝品組成物。然後，這些審議員以5等級規模為基準評估清爽時以及霧面感(等級1：非常差，等級2：差，等級3：滿意，等級4：好，等級5：優異)。結果呈現於下表5。 [表5]
從表5的結果可看出，相較於比較例，根據實例之組成物提供較佳的清爽感及霧面感。It can be seen from the results in Table 5 that compared with the comparative example, the composition according to the example provides a better refreshing feeling and matte feeling.
無none
圖1為說明根據本揭露一實施例兩親各向異性粉末形成的示意圖。 圖2顯示根據實例1及比較例1之水包矽型乳液組成物之電子顯微鏡圖，於製備後立刻拍攝(a)以及將每一組成物儲存於30℃下4週後拍攝(b)。 圖3顯示根據實例2及比較例2之水包矽型乳液組成物之電子顯微鏡圖，於製備後立刻拍攝(a)以及將每一組成物儲存於30℃下4週後拍攝(b)。 圖4顯示實例1、2以及比較例1、2之每一組成物儲存於60℃下3天後之組成物的圖相。FIG. 1 is a schematic diagram illustrating the formation of amphiphilic anisotropic powder according to an embodiment of the present disclosure. Figure 2 shows the electron micrographs of the silicon-in-water emulsion composition according to Example 1 and Comparative Example 1, taken immediately after preparation (a) and after storing each composition at 30°C for 4 weeks (b). Fig. 3 shows the electron microscope images of the silicon-in-water emulsion composition according to Example 2 and Comparative Example 2, taken immediately after preparation (a) and after storing each composition at 30°C for 4 weeks (b). Figure 4 shows the phases of each composition of Examples 1 and 2 and Comparative Examples 1 and 2 after being stored at 60°C for 3 days.
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