TW366345B - Substituted liposaccharides useful in the treatment and prevention of endotoxemia - Google Patents
Substituted liposaccharides useful in the treatment and prevention of endotoxemiaInfo
- Publication number
- TW366345B TW366345B TW085106735A TW85106735A TW366345B TW 366345 B TW366345 B TW 366345B TW 085106735 A TW085106735 A TW 085106735A TW 85106735 A TW85106735 A TW 85106735A TW 366345 B TW366345 B TW 366345B
- Authority
- TW
- Taiwan
- Prior art keywords
- endotoxemia
- treatment
- prevention
- useful
- substituted liposaccharides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/461,675 US5750664A (en) | 1995-06-05 | 1995-06-05 | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
Publications (1)
Publication Number | Publication Date |
---|---|
TW366345B true TW366345B (en) | 1999-08-11 |
Family
ID=23833509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW085106735A TW366345B (en) | 1995-06-05 | 1996-06-05 | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
Country Status (21)
Country | Link |
---|---|
US (8) | US5750664A (zh) |
EP (1) | EP0853627B1 (zh) |
JP (3) | JP4009318B2 (zh) |
KR (1) | KR100416335B1 (zh) |
CN (1) | CN1067082C (zh) |
AT (1) | ATE258185T1 (zh) |
AU (1) | AU707779C (zh) |
CA (1) | CA2223140C (zh) |
DE (1) | DE69631376T2 (zh) |
DK (1) | DK0853627T3 (zh) |
ES (1) | ES2214543T3 (zh) |
HU (1) | HU221342B1 (zh) |
IL (2) | IL122251A0 (zh) |
MX (1) | MX9709502A (zh) |
NO (1) | NO310239B1 (zh) |
NZ (1) | NZ312299A (zh) |
PT (1) | PT853627E (zh) |
RU (1) | RU2170738C2 (zh) |
TW (1) | TW366345B (zh) |
WO (1) | WO1996039411A1 (zh) |
ZA (1) | ZA964666B (zh) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750664A (en) * | 1995-06-05 | 1998-05-12 | Eisai Co., Ltd. | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
US6417172B1 (en) * | 1995-06-05 | 2002-07-09 | Eisai Co., Ltd. | Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs |
ES2242226T3 (es) * | 1996-07-03 | 2005-11-01 | Eisai Co., Ltd. | Composiciones que contienen analogos del lipido a y procedimiento parasu preparacion. |
WO2000013029A1 (fr) | 1998-09-01 | 2000-03-09 | Eisai Co., Ltd | Procede pour evaluer des injections contenant des analogues de lipide a |
US20030130212A1 (en) * | 1999-01-14 | 2003-07-10 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by intravenous infusion |
ATE501760T1 (de) * | 1999-01-14 | 2011-04-15 | Eisai R&D Man Co Ltd | E5564 zur verwendung in der behandlung von allograft-abstossung oder host-versus-graft- erkrankungen |
US6835721B2 (en) | 1999-02-01 | 2004-12-28 | Eisai Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
US20040006242A1 (en) * | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
US7915238B2 (en) * | 1999-02-01 | 2011-03-29 | Eisai R & D Management Co., Ltd. | Immunomodulatory compounds and methods of use thereof |
PL350032A1 (en) * | 1999-02-10 | 2002-10-21 | Sankyo Co | Ether type lipid a1-carboxylic acid analogues |
US20040127456A1 (en) * | 2000-01-14 | 2004-07-01 | Melvyn Lynn | Prevention and treatment of endotoxemia and related complications associated with surgery |
US20050101549A1 (en) * | 2000-01-14 | 2005-05-12 | Melvyn Lynn | Prevention and treatment of endotoxemia and related complications associated with surgery |
AU3850701A (en) * | 2000-02-18 | 2001-08-27 | Eisai Co Ltd | Micelles |
US6861512B2 (en) | 2000-03-01 | 2005-03-01 | Eisai Co., Ltd. | Separation of olefinic isomers |
US20030105033A1 (en) * | 2000-06-09 | 2003-06-05 | Rossignol Daniel P. | Administration of an anti-endotoxin drug by bolus or intermittent intravenous infusion |
EP1363642A4 (en) * | 2000-06-09 | 2005-02-02 | Eisai Co Ltd | ADMINISTRATION OF ANTI-ENDOTOXIN DRUG BY INJECTION OF A BOWL OR BY INTERMITTENT INTRAVENOUS INFUSION |
WO2002088072A1 (fr) * | 2001-04-23 | 2002-11-07 | Eisai Co., Ltd. | Procede de preparation de composes d'alkylene |
JPWO2002088062A1 (ja) * | 2001-04-23 | 2004-08-12 | エーザイ株式会社 | アルコール誘導体の製造方法 |
US20040198652A1 (en) * | 2001-04-24 | 2004-10-07 | Carter J. Paul | Methods and compositions for preventing and treating septic shock and endotoxemia |
JP4366081B2 (ja) * | 2001-05-22 | 2009-11-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 高度に精製されたアンチエンドトキシン化合物 |
DE10125179A1 (de) * | 2001-05-23 | 2002-12-05 | Laves Ralph Georg | Verwendung von LPS zur Behandlung intestinaler Entzündungsprozesse |
US7727974B2 (en) * | 2001-08-10 | 2010-06-01 | Eisai R & D Management Co., Ltd. | Methods of reducing the severity of mucositis |
EP1420798A4 (en) * | 2001-08-10 | 2007-07-25 | Eisai Co Ltd | TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS RELATED TO HEAT SHOCK PROTEIN |
WO2003050137A2 (en) * | 2001-12-11 | 2003-06-19 | David Schwartz | Toll-like receptor 4 mutations |
AU2002950657A0 (en) * | 2002-08-08 | 2002-09-12 | Alchemia Limited | Derivatives of monosaccharides for drug discovery |
AU2002951995A0 (en) * | 2002-10-11 | 2002-10-31 | Alchemia Limited | Classes of compounds that interact with gpcrs |
WO2004058788A1 (ja) * | 2002-12-24 | 2004-07-15 | Sankyo Company, Limited | 右糖グルコースリピドa類縁体 |
JP4838706B2 (ja) * | 2003-01-06 | 2011-12-14 | コリクサ コーポレイション | 所定のアミノアルキルグルコサミニドフォスフェート化合物及びそれらの使用 |
JP4773336B2 (ja) * | 2003-02-20 | 2011-09-14 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Lpsアンタゴニストb1287およびその立体異性体の調製のための試薬および方法 |
CN1780824A (zh) * | 2003-03-05 | 2006-05-31 | 卫材株式会社 | 预防和治疗内毒素相关疾病和病症的组合物和方法 |
WO2005027826A2 (en) * | 2003-07-14 | 2005-03-31 | Eisai, Co, Ltd. | Methods and treating severe acute respiratory syndrome |
WO2005059517A2 (en) | 2003-12-16 | 2005-06-30 | University Of Massachusetts | Toll-like receptor assays |
CN1930180B (zh) * | 2004-01-08 | 2010-05-26 | 三共株式会社 | 左侧葡萄糖脂a类似物 |
US20070292418A1 (en) * | 2005-04-26 | 2007-12-20 | Eisai Co., Ltd. | Compositions and methods for immunotherapy |
JP5185813B2 (ja) * | 2005-04-26 | 2013-04-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 癌免疫治療のための組成物および方法 |
US20100015125A1 (en) * | 2005-06-17 | 2010-01-21 | University Of Rochester | Methods and compositions for enhancing immune memory by blocking intrahepatic activated t cell deletion |
EP1939209A4 (en) * | 2005-08-31 | 2010-07-07 | Eisai R&D Man Co Ltd | PROCESS FOR PREPARING A LIPID A ANALOGON |
JP5118968B2 (ja) * | 2005-08-31 | 2013-01-16 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リピッドa類縁体の製造方法 |
US7943588B2 (en) | 2006-03-28 | 2011-05-17 | Trustees Of Dartmouth College | Method for preventing or treating neuropathic pain |
WO2008059307A2 (en) * | 2006-11-16 | 2008-05-22 | Om Pharma | Functionalized beta 1,6 glucosamine disaccharides and process for their preparation |
ES2392890T3 (es) * | 2006-11-22 | 2012-12-14 | Eisai R&D Management Co., Ltd. | Sal sódica de un compuesto disacarídico, procedimiento para la producción de la misma y uso de la misma |
WO2008062842A1 (en) | 2006-11-22 | 2008-05-29 | Eisai R & D Management Co., Ltd. | Sodium salt of disaccharide compound, method for producing the same, and use of the same |
AU2007323134B2 (en) | 2006-11-23 | 2013-05-02 | Cadila Pharmaceuticals Limited | Poly-TLR antagonist |
US20110201569A1 (en) * | 2009-09-16 | 2011-08-18 | Heidi Ehrentraut | Methods For Treating Myocardial Disorders |
WO2011038537A1 (zh) * | 2009-09-29 | 2011-04-07 | 上海南方基因科技有限公司 | 败血症以及败血症休克的预测、预防和治疗方法及试剂盒 |
GB201013785D0 (en) | 2010-08-17 | 2010-09-29 | Ucl Business Plc | Treatment |
JP2012246470A (ja) | 2011-05-31 | 2012-12-13 | Sharp Corp | 半導体ナノ粒子の製造方法、半導体ナノ粒子、ならびにこれを用いた蛍光体 |
CN107474019A (zh) * | 2011-12-22 | 2017-12-15 | 纳米技术有限公司 | 表面改性的纳米粒子 |
US9132141B2 (en) | 2012-03-28 | 2015-09-15 | University Of Maryland, Baltimore | Administration of eritoran or pharmaceutically acceptable salts thereof to treat orthomyxovirus infections |
WO2014113048A1 (en) * | 2013-01-18 | 2014-07-24 | Loma Linda University | Compositions and methods for diagnosing and treating sepsis |
AU2014287002A1 (en) | 2013-07-11 | 2016-02-11 | Alnylam Pharmaceuticals, Inc. | Oligonucleotide-ligand conjugates and process for their preparation |
US9584991B1 (en) * | 2014-06-19 | 2017-02-28 | Isaac S. Daniel | Method of communicating and accessing social networks using interactive coded messages |
WO2017173024A1 (en) * | 2016-03-30 | 2017-10-05 | AyuVis Research LLC | Novel compositions and therapeutic methods |
PL3795576T3 (pl) * | 2016-09-14 | 2023-09-11 | Genomatica, Inc. | Związki stanowiące 1,3-diole tłuszczowe i ich pochodne glikozylowane |
EP3512508B1 (en) * | 2016-09-16 | 2022-03-16 | Eisai R&D Management Co., Ltd. | Method of use of eritoran as a tlr4 antagonist for treatment of ebola and marburg disease |
JP7487187B2 (ja) * | 2018-12-17 | 2024-05-20 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | リポソームを含む製剤 |
WO2021207218A1 (en) | 2020-04-06 | 2021-10-14 | Eisai R&D Management Co., Ltd. | Treatment of nidovirales infection with eritoran |
CN113527396B (zh) * | 2020-04-17 | 2024-02-02 | 上海医药工业研究院 | 一种疫苗佐剂mpla的中间体、合成及应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4495346A (en) * | 1981-03-30 | 1985-01-22 | Wisconsin Alumni Research Foundation | Method of preparing a disaccharide |
US4987237A (en) * | 1983-08-26 | 1991-01-22 | Ribi Immunochem Research, Inc. | Derivatives of monophosphoryl lipid A |
US5066794A (en) * | 1984-08-24 | 1991-11-19 | Daiichi Pharmaceutical Co., Ltd. | Process for preparing a disaccharide derivative |
JPS6153295A (ja) * | 1984-08-24 | 1986-03-17 | Dai Ichi Seiyaku Co Ltd | ジサツカライド誘導体 |
NL8601551A (nl) * | 1985-06-28 | 1987-01-16 | Sandoz Ag | Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten. |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
US5158939A (en) * | 1989-07-21 | 1992-10-27 | Wisconsin Alumni Research Foundation | Method of stimulating the immune systems of animals and compositions useful therefor |
JP2839916B2 (ja) * | 1989-10-20 | 1998-12-24 | 三共株式会社 | リピドa3位エーテル類縁体 |
PT94481B (pt) | 1989-12-11 | 1997-02-28 | Sankyo Co | Processo para a preparacao de analogos de lipidos a tendo imunoactividade e actividade anti-tumoral |
JP2847319B2 (ja) | 1990-05-18 | 1999-01-20 | イビデン株式会社 | 電子部品搭載用多層ボンディング基板 |
JP3040847B2 (ja) | 1990-06-22 | 2000-05-15 | 三共株式会社 | リピドx類縁体 |
US5530113A (en) * | 1991-10-11 | 1996-06-25 | Eisai Co., Ltd. | Anti-endotoxin compounds |
AU660325B2 (en) * | 1991-10-11 | 1995-06-22 | Eisai Co. Ltd. | Anti-endotoxin compounds and related molecules and methods |
JP3135990B2 (ja) | 1992-07-31 | 2001-02-19 | 沖電気工業株式会社 | パリティ付加回路 |
US5413785A (en) * | 1993-01-27 | 1995-05-09 | New England Deaconess Hospital Corp. | Methodology employing lactobacillus GG for reduction of plasma endotoxin levels circulating in-vivo |
US6417172B1 (en) | 1995-06-05 | 2002-07-09 | Eisai Co., Ltd. | Prevention and treatment of pulmonary bacterial infection or symptomatic pulmonary exposure to endotoxin by inhalation of antiendotoxin drugs |
US5750664A (en) * | 1995-06-05 | 1998-05-12 | Eisai Co., Ltd. | Substituted liposaccharides useful in the treatment and prevention of endotoxemia |
JP4235193B2 (ja) | 2005-06-07 | 2009-03-11 | 日本電信電話株式会社 | イベント履歴蓄積装置、イベント情報検証装置、イベント履歴蓄積方法、イベント情報検証方法およびイベント情報処理システム |
-
1995
- 1995-06-05 US US08/461,675 patent/US5750664A/en not_active Expired - Lifetime
- 1995-06-05 US US08/461,677 patent/US5681824A/en not_active Expired - Lifetime
-
1996
- 1996-06-05 EP EP96923234A patent/EP0853627B1/en not_active Expired - Lifetime
- 1996-06-05 CA CA002223140A patent/CA2223140C/en not_active Expired - Lifetime
- 1996-06-05 NZ NZ312299A patent/NZ312299A/xx not_active IP Right Cessation
- 1996-06-05 CN CN96195890A patent/CN1067082C/zh not_active Expired - Lifetime
- 1996-06-05 HU HU9802662A patent/HU221342B1/hu unknown
- 1996-06-05 AU AU63802/96A patent/AU707779C/en not_active Expired
- 1996-06-05 ZA ZA964666A patent/ZA964666B/xx unknown
- 1996-06-05 PT PT96923234T patent/PT853627E/pt unknown
- 1996-06-05 JP JP50186897A patent/JP4009318B2/ja not_active Expired - Lifetime
- 1996-06-05 DE DE69631376T patent/DE69631376T2/de not_active Expired - Lifetime
- 1996-06-05 TW TW085106735A patent/TW366345B/zh not_active IP Right Cessation
- 1996-06-05 WO PCT/US1996/009578 patent/WO1996039411A1/en active IP Right Grant
- 1996-06-05 RU RU98100107/04A patent/RU2170738C2/ru active
- 1996-06-05 AT AT96923234T patent/ATE258185T1/de active
- 1996-06-05 DK DK96923234T patent/DK0853627T3/da active
- 1996-06-05 ES ES96923234T patent/ES2214543T3/es not_active Expired - Lifetime
- 1996-06-05 KR KR1019970708583A patent/KR100416335B1/ko not_active IP Right Cessation
- 1996-06-05 US US08/658,656 patent/US5935938A/en not_active Expired - Lifetime
- 1996-06-05 IL IL12225196A patent/IL122251A0/xx not_active IP Right Cessation
-
1997
- 1997-12-04 NO NO19975644A patent/NO310239B1/no not_active IP Right Cessation
- 1997-12-04 MX MX9709502A patent/MX9709502A/es unknown
-
1999
- 1999-04-16 US US09/293,856 patent/US6184366B1/en not_active Expired - Lifetime
-
2001
- 2001-01-30 US US09/774,541 patent/US20020028927A1/en not_active Abandoned
-
2002
- 2002-05-13 US US10/144,670 patent/US20030144503A1/en not_active Abandoned
- 2002-06-02 IL IL149971A patent/IL149971A/en not_active IP Right Cessation
-
2007
- 2007-06-11 JP JP2007154127A patent/JP4712001B2/ja not_active Expired - Lifetime
- 2007-07-30 US US11/830,412 patent/US7737129B2/en not_active Expired - Fee Related
-
2010
- 2010-05-17 US US12/781,166 patent/US7994154B2/en not_active Expired - Fee Related
-
2011
- 2011-01-31 JP JP2011018401A patent/JP2011121970A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TW366345B (en) | Substituted liposaccharides useful in the treatment and prevention of endotoxemia | |
ZA965887B (en) | Improved cement admixture product. | |
MX9800625A (es) | Marcfortinas y paraherquamidas antiparasitarias. | |
IL131332A (en) | Methods and products for analyzing polymers | |
FI960780A0 (fi) | Nolla intermediaarinen frekvenssivastaanotin | |
GB9603518D0 (en) | Novel process | |
ZA977371B (en) | Article of clothing. | |
CY2440B1 (en) | Process improvement in the synthesis of N-A3-(3-cyanopyrazolo A1,5-aUpyrimidin-7-yl)phenylU-N-ethyl-acetamide. | |
DE69607387D1 (en) | Tragbare küche für camping | |
ZA974084B (en) | Novel α-glucuronidases, production hereof and their uses. | |
GB9615025D0 (en) | Production of substituted polyisobutenes | |
ZA966757B (en) | Novel compounds and process. | |
ZA969721B (en) | Method of treating sepsis. | |
HU9402646D0 (en) | Anomere fluoro-ribosyl-amines | |
EP0821691A4 (en) | METHOD FOR SYNTHESIS OF GM2 | |
GB9621822D0 (en) | Novel process | |
HUT69373A (en) | N-substituted 2-azetidinones, as intermediates in novel process of n-ansubstituted 2-azetidinones | |
GB9602862D0 (en) | Novel process | |
ZA975061B (en) | Manufacture of articles. | |
ZA967371B (en) | Pulley block. | |
AU115632S (en) | Door handle | |
ZA979001B (en) | Pulley block. | |
HU9600288D0 (en) | Bihari csipoes variety of horse-radish (armoratia l.) | |
GB9412912D0 (en) | Sex reversal enzyme | |
PL101899U1 (en) | Camping chamber-pot |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK4A | Expiration of patent term of an invention patent |