TW284759B - - Google Patents
Info
- Publication number
- TW284759B TW284759B TW082105769A TW82105769A TW284759B TW 284759 B TW284759 B TW 284759B TW 082105769 A TW082105769 A TW 082105769A TW 82105769 A TW82105769 A TW 82105769A TW 284759 B TW284759 B TW 284759B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95222292A | 1992-09-28 | 1992-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW284759B true TW284759B (zh) | 1996-09-01 |
Family
ID=25492671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW082105769A TW284759B (zh) | 1992-09-28 | 1993-07-20 |
Country Status (15)
Country | Link |
---|---|
US (2) | US5728704A (zh) |
EP (1) | EP0662962A1 (zh) |
JP (1) | JP2789134B2 (zh) |
KR (1) | KR950703539A (zh) |
AU (1) | AU683620B2 (zh) |
CA (1) | CA2145640C (zh) |
FI (1) | FI934224A (zh) |
HU (1) | HU220669B1 (zh) |
IL (1) | IL107085A (zh) |
MY (1) | MY115288A (zh) |
NO (1) | NO306598B1 (zh) |
NZ (1) | NZ254550A (zh) |
TW (1) | TW284759B (zh) |
WO (1) | WO1994007867A1 (zh) |
ZA (1) | ZA937142B (zh) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ254550A (en) * | 1992-09-28 | 1997-08-22 | Pfizer | Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications |
DK0640599T3 (da) * | 1993-08-26 | 1998-09-28 | Ono Pharmaceutical Co | 4-Aminopyrimidin-derivater |
GB9325217D0 (en) * | 1993-12-09 | 1994-02-09 | Zeneca Ltd | Pyrimidine derivatives |
PT791355E (pt) * | 1996-02-29 | 2002-08-30 | Pfizer | Metodo para diminuir os daos associados com a isquemia nos tecidos |
US6284748B1 (en) | 1997-03-07 | 2001-09-04 | Metabasis Therapeutics, Inc. | Purine inhibitors of fructose 1,6-bisphosphatase |
US6054587A (en) * | 1997-03-07 | 2000-04-25 | Metabasis Therapeutics, Inc. | Indole and azaindole inhibitors of fructose-1,6-bisphosphatase |
EP1402895A1 (en) * | 1997-03-07 | 2004-03-31 | Metabasis Therapeutics, Inc. | Benzimidazole inhibitors of fructose 1,6-biphosphatase |
AU6691498A (en) * | 1997-03-07 | 1998-09-22 | Metabasis Therapeutics, Inc. | Novel benzimidazole inhibitors of fructose-1,6-bisphosphatase |
DE19710435A1 (de) * | 1997-03-13 | 1998-09-17 | Hoechst Ag | Verwendung von Pyrimidinderivaten zur Prävention von Krebs allein oder in Kombination mit anderen therapeutischen Maßnahmen |
ES2363230T3 (es) * | 1997-04-15 | 2011-07-27 | Csir | Métodos no terapéuticos para suprimir el apetito. |
IL124236A (en) * | 1997-05-05 | 2003-01-12 | Pfizer | Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor |
CN101125864A (zh) * | 1998-09-09 | 2008-02-20 | 症变治疗公司 | 新的果糖1,6-二磷酸酶的杂芳族抑制剂 |
AU2003242500B2 (en) * | 1998-09-09 | 2006-11-02 | Metabasis Therapeutics, Inc. | Novel Heteroaromatic Inhibitors of Fructose 1,6-bisphosphatase |
CA2343027A1 (en) * | 1998-09-09 | 2000-03-16 | Metabasis Therapeutics, Inc. | Novel heteroaromatic inhibitors of fructose 1,6-bisphosphatase |
US6756360B1 (en) * | 1998-12-24 | 2004-06-29 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes |
EP1185275A1 (en) | 1999-04-01 | 2002-03-13 | Pfizer Products Inc. | Aminopyrimidines as sorbitol dehydrogenase inhibitors |
ES2215570T3 (es) | 1999-04-01 | 2004-10-16 | Pfizer Products Inc. | Compuestos para tratar y prevenir complicaciones diabeticas. |
GB2396815B (en) * | 1999-10-27 | 2004-09-08 | Phytopharm Plc | A composition comprising a pregnenone derivative and an NSAID |
US6380200B1 (en) * | 1999-12-07 | 2002-04-30 | Pfizer, Inc. | Combination of aldose reductase inhibitors and selective serotonin reuptake inhibitors for the treatment of diabetic complications |
AU784370B2 (en) * | 1999-12-22 | 2006-03-23 | Metabasis Therapeutics, Inc. | Novel bisamidate phosphonate prodrugs |
ATE350385T1 (de) * | 2000-03-08 | 2007-01-15 | Metabasis Therapeutics Inc | Neue aryl fructose-1,6-bisphosphatase inhibitoren |
US7563774B2 (en) * | 2000-06-29 | 2009-07-21 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes |
GB2363985B (en) * | 2000-06-30 | 2004-09-29 | Phytopharm Plc | Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use |
DE60123458T2 (de) * | 2000-11-10 | 2007-08-02 | F. Hoffmann-La Roche Ag | Pyrimidinderivate und deren verwendung als neuropeptid-y-rezeptorliganden |
SK6192003A3 (en) * | 2000-11-30 | 2004-07-07 | Pfizer Prod Inc | Combination of GABA agonists and sorbitol dehydrogenase inhibitors |
JP2004514700A (ja) * | 2000-11-30 | 2004-05-20 | ファイザー・プロダクツ・インク | Gabaアゴニスト及びアルドース還元酵素阻害剤の組み合わせ |
US6555573B2 (en) * | 2000-12-21 | 2003-04-29 | The Quigley Corporation | Method and composition for the topical treatment of diabetic neuropathy |
US20040127502A1 (en) * | 2001-01-31 | 2004-07-01 | Synaptic Pharmaceutical Corporation | Use of GAL3 antagonist for treatment of depression |
US7081470B2 (en) * | 2001-01-31 | 2006-07-25 | H. Lundbeck A/S | Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods |
EP1247809A3 (en) * | 2001-03-30 | 2003-12-17 | Pfizer Products Inc. | Triazine compounds useful as sorbitol dehydrogenase inhibitors |
US6825198B2 (en) | 2001-06-21 | 2004-11-30 | Pfizer Inc | 5-HT receptor ligands and uses thereof |
WO2003033643A2 (en) * | 2001-10-15 | 2003-04-24 | Pfizer Products Inc. | Three dimensional crystal structure of human sorbitol dehydrogenase and uses thereof |
US20030105027A1 (en) * | 2001-11-06 | 2003-06-05 | Rosenbloom Richard A. | Nutritional supplements and methods for prevention, reduction and treatment of radiation injury |
US7435725B2 (en) * | 2001-11-06 | 2008-10-14 | The Quigly Corporation | Oral compositions and methods for prevention, reduction and treatment of radiation injury |
US20040142932A1 (en) * | 2002-01-18 | 2004-07-22 | Michael Hepperle | Substituted pyridazinones |
CN1646500A (zh) * | 2002-03-13 | 2005-07-27 | 欧洲凯尔特股份有限公司 | 芳基取代的嘧啶及其用途 |
WO2004000318A2 (en) * | 2002-06-21 | 2003-12-31 | Cellular Genomics, Inc. | Certain amino-substituted monocycles as kinase modulators |
AU2003245669A1 (en) * | 2002-06-21 | 2004-01-06 | Cellular Genomics, Inc. | Certain aromatic monocycles as kinase modulators |
US7083813B2 (en) * | 2002-11-06 | 2006-08-01 | The Quigley Corporation | Methods for the treatment of peripheral neural and vascular ailments |
US7262318B2 (en) * | 2004-03-10 | 2007-08-28 | Pfizer, Inc. | Substituted heteroaryl- and phenylsulfamoyl compounds |
WO2005110413A2 (en) | 2004-05-19 | 2005-11-24 | Solvay Pharmaceuticals Gmbh | Medicaments containing n-sulfamoyl-n'-arylpiperazines for the prophylaxis or treatment of obesity and related conditions |
US20050261292A1 (en) * | 2004-05-19 | 2005-11-24 | Solvay Pharmaceuticals Gmbh | Pharmaceutical composition containing N-sulfamoyl-N'-arylpiperazines for the treatment or inhibition of obesity and related conditions |
US20050288340A1 (en) * | 2004-06-29 | 2005-12-29 | Pfizer Inc | Substituted heteroaryl- and phenylsulfamoyl compounds |
GB0415364D0 (en) | 2004-07-09 | 2004-08-11 | Astrazeneca Ab | Pyrimidine derivatives |
CN101005847A (zh) * | 2004-08-18 | 2007-07-25 | 症变治疗公司 | 果糖1,6-双磷酸酶的新颖噻唑类抑制剂 |
AU2005286592A1 (en) * | 2004-09-23 | 2006-03-30 | Reddy Us Therapeutics, Inc. | Novel pyrimidine compounds, process for their preparation and compositions containing them |
WO2006056845A1 (en) * | 2004-11-23 | 2006-06-01 | Warner-Lambert Company Llc | 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for the treatment of lipidemia |
EP1836183A2 (en) * | 2004-12-13 | 2007-09-26 | Galileo Pharmaceuticals, Inc. | Spiro derivatives as lipoxygenase inhibitors |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
EP1973884B1 (en) * | 2006-01-19 | 2016-08-03 | Orchid Pharma Limited | Novel heterocycles |
US7863446B2 (en) * | 2006-01-19 | 2011-01-04 | Orchid Research Laboratories Limited | Heterocycles |
US8158667B2 (en) * | 2006-08-21 | 2012-04-17 | Kador Peter F | Topical treatment of cataracts in dogs |
ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
US20090018151A1 (en) * | 2007-02-23 | 2009-01-15 | Ezekiel Fink | Topical Treatment of Peripheral diabetic complications |
US8877717B2 (en) | 2007-03-12 | 2014-11-04 | Zadec Aps | Anti-diabetic extract of rooibos |
PE20090422A1 (es) | 2007-04-27 | 2009-04-18 | Purdue Pharma Lp | Derivados de piperidina, piperazina o tetrahidropiridilo como antagonistas de trpv1 |
EP2245017A4 (en) | 2008-02-01 | 2011-12-28 | Orchid Res Lab Ltd | NEW HETEROCYCLES |
EP2571860A1 (en) | 2010-05-21 | 2013-03-27 | Pfizer Inc | 2-phenyl benzoylamides |
US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
JP2014513923A (ja) | 2011-03-04 | 2014-06-19 | ファイザー・インク | Edn3様ペプチドおよびその使用 |
PE20141531A1 (es) | 2011-06-22 | 2014-10-23 | Purdue Pharma Lp | Antagonistas de trpv1 que incluyen sustituyentes dihidroxi y sus usos |
AU2014255381A1 (en) | 2013-04-17 | 2015-10-08 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
ES2836500T3 (es) | 2016-06-21 | 2021-06-25 | Univ Columbia | Inhibidores de aldosa reductasa y métodos de uso de los mismos |
MX2020001057A (es) | 2017-07-28 | 2020-11-24 | Applied Therapeutics Inc | Composiciones y metodos para tratar la galactosemia. |
CN108101883B (zh) * | 2018-01-31 | 2018-11-13 | 佳木斯大学附属第一医院 | 一种用于防治糖尿病视网膜病变的药物及其制备方法 |
EP3911648A4 (en) | 2019-01-18 | 2022-10-26 | Astrazeneca AB | PCSK9 INHIBITORS AND METHODS OF USE THEREOF |
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FR1063014A (fr) * | 1950-06-14 | 1954-04-29 | Wellcome Found | Dérivés de pyrimidine et leur préparation |
GB959699A (en) * | 1961-06-09 | 1964-06-03 | May & Baker Ltd | New pyrimidine derivatives |
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IE47592B1 (en) * | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
FR2489141A1 (fr) * | 1980-09-03 | 1982-03-05 | Sevifra | Appareil chirurgical pour la decoupe precise de la cornee |
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CA1176269A (en) * | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
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DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
US4996204A (en) * | 1989-05-11 | 1991-02-26 | Pfizer Inc. | Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors |
US5039672A (en) * | 1990-04-05 | 1991-08-13 | Pfizer Inc. | Heterocyclic compounds as aldose reductase inhibitors |
US5098904A (en) * | 1990-06-27 | 1992-03-24 | Bristol-Myers Squibb Company | Cerebral function enhancing pyrimidinyl derivatives |
GB9016984D0 (en) * | 1990-08-02 | 1990-09-19 | Ici Plc | Aniline derivatives |
DE4025387A1 (de) * | 1990-08-10 | 1992-02-13 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als reagenzien |
US5589477A (en) * | 1990-08-31 | 1996-12-31 | Nippon Shinyaku Company, Limited | Pyrimidine derivatives and drugs |
NZ254550A (en) * | 1992-09-28 | 1997-08-22 | Pfizer | Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications |
-
1993
- 1993-07-12 NZ NZ254550A patent/NZ254550A/xx unknown
- 1993-07-12 JP JP6509004A patent/JP2789134B2/ja not_active Expired - Fee Related
- 1993-07-12 US US08/406,947 patent/US5728704A/en not_active Expired - Fee Related
- 1993-07-12 WO PCT/US1993/006446 patent/WO1994007867A1/en not_active Application Discontinuation
- 1993-07-12 KR KR1019950701168A patent/KR950703539A/ko not_active Application Discontinuation
- 1993-07-12 AU AU46697/93A patent/AU683620B2/en not_active Ceased
- 1993-07-12 CA CA002145640A patent/CA2145640C/en not_active Expired - Fee Related
- 1993-07-12 EP EP93917043A patent/EP0662962A1/en not_active Ceased
- 1993-07-20 TW TW082105769A patent/TW284759B/zh active
- 1993-09-23 IL IL10708593A patent/IL107085A/en not_active IP Right Cessation
- 1993-09-23 MY MYPI93001941A patent/MY115288A/en unknown
- 1993-09-27 FI FI934224A patent/FI934224A/fi not_active Application Discontinuation
- 1993-09-27 ZA ZA937142A patent/ZA937142B/xx unknown
- 1993-09-27 HU HU9302734A patent/HU220669B1/hu not_active IP Right Cessation
-
1995
- 1995-03-27 NO NO951155A patent/NO306598B1/no unknown
-
1997
- 1997-12-01 US US08/980,559 patent/US5866578A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5866578A (en) | 1999-02-02 |
EP0662962A1 (en) | 1995-07-19 |
JPH07507072A (ja) | 1995-08-03 |
NO951155D0 (no) | 1995-03-27 |
JP2789134B2 (ja) | 1998-08-20 |
IL107085A0 (en) | 1993-12-28 |
NO951155L (no) | 1995-05-26 |
US5728704A (en) | 1998-03-17 |
MY115288A (en) | 2003-05-31 |
FI934224A0 (fi) | 1993-09-27 |
IL107085A (en) | 2001-01-11 |
CA2145640A1 (en) | 1994-04-14 |
NO306598B1 (no) | 1999-11-29 |
ZA937142B (en) | 1995-03-23 |
AU4669793A (en) | 1994-04-26 |
KR950703539A (ko) | 1995-09-20 |
FI934224A (fi) | 1994-03-29 |
NZ254550A (en) | 1997-08-22 |
HUT65531A (en) | 1994-06-28 |
CA2145640C (en) | 2001-01-30 |
HU9302734D0 (en) | 1993-12-28 |
HU220669B1 (hu) | 2002-04-29 |
AU683620B2 (en) | 1997-11-20 |
WO1994007867A1 (en) | 1994-04-14 |