TW201730100A - A composition capable of fast locally producing oxygen which uses the peroxide as the oxygen-supplying source, which is selected from groups of the peroxide and superoxide - Google Patents

A composition capable of fast locally producing oxygen which uses the peroxide as the oxygen-supplying source, which is selected from groups of the peroxide and superoxide Download PDF

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TW201730100A
TW201730100A TW105105069A TW105105069A TW201730100A TW 201730100 A TW201730100 A TW 201730100A TW 105105069 A TW105105069 A TW 105105069A TW 105105069 A TW105105069 A TW 105105069A TW 201730100 A TW201730100 A TW 201730100A
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oxygen
peroxide
superoxide
generating composition
oxygen generating
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TW105105069A
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Chinese (zh)
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Garry Tsaur
Banker Tsaur
Frank Tsaur
Ting-Hua Wang
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Garry Tsaur
Banker Tsaur
Frank Tsaur
Ting-Hua Wang
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Abstract

The purpose of the present invention lies in providing a composition capable of fast locally producing oxygen, which uses the peroxide as the oxygen-supplying source, wherein the oxygen-supplying source is selected from groups of the peroxide and superoxide. By taking advantage of sweating of the skin sweat gland, the body fluid of wound, and evaporation of the blood to form the hydrogen oxide and oxygen, together with the catalyst to increase the oxygen generation speed, the present invention can produce a great amount of oxygen in short period of time, so that the wounded area in small environment is protected by the high-purity oxygen to inhibit propagation of the anaerobe, helpful for curing of the wound and the hygiene care.

Description

一種可局部快速產生氧氣組合物Locally rapid production of oxygen composition

本發明係關於一種可局部快速產生氧氣組合物,以過氧化物為供氧源,並搭配以催化劑增加氧氣生產速度,得以在短時間內於小環境中大量產生氧氣,抑制細菌生長。 The invention relates to a locally rapid oxygen generating composition, which uses a peroxide as an oxygen source and is combined with a catalyst to increase the oxygen production rate, so that a large amount of oxygen can be generated in a small environment in a short time to inhibit bacterial growth.

在人體表面的傷口,不論是擦傷、割傷、刺傷、撕裂傷都會因為微血管破裂導致相當程度的失血,嚴重者可能導致皮下血腫,血腫會壓迫血管造成局部區域缺氧,雖然傷口經過處理也已經包紮,包紮本身及較深的傷口也會造成缺氧,缺氧使厭氧菌大量繁殖,造成感染,影響傷口癒合。 Wounds on the surface of the human body, whether it is abrasions, cuts, stab wounds or lacerations, may cause considerable blood loss due to microvascular rupture. In severe cases, subcutaneous hematoma may occur, and the hematoma may compress the blood vessels to cause local area hypoxia, although the wound is treated. Already dressing, dressing itself and deeper wounds can also cause hypoxia. Hypoxia causes anaerobic bacteria to multiply, causing infection and affecting wound healing.

女性在生理期期間因為外陰部酸鹼值改變或體力、免疫力下降等原因都可能導致外陰***炎,再加上生理期期間使用的衛生護墊、衛生棉及衛生棉條,造成陰部缺氧、潮濕、悶熱,使黴菌、真菌、葡萄球菌等厭氧菌大量繁殖,引起婦科炎症。 During the physiological period, women may cause vulvovaginitis due to changes in the pH value of the vulva or decreased physical strength and immunity. In addition, the sanitary pads, sanitary napkins and tampon used during the physiological period may cause hypoxia in the genitals. , damp, sultry, so that mold, fungi, staphylococcus and other anaerobic bacteria multiply, causing gynecological inflammation.

皮膚傷口、外陰部等人體表面因為缺氧,造成厭氧的真菌與細菌大量繁殖生長,造成感染、發炎,影響人類的健康與生命安全,因此如何抑制人體表面細菌生長為大眾所關心的議題。 Skin surface wounds, genitals and other human surface due to lack of oxygen, causing anaerobic fungi and bacteria to multiply and grow, causing infection, inflammation, affecting human health and life safety, so how to inhibit the growth of human surface bacteria is a topic of public concern.

台灣專利(申請號095134585)為一種傷口覆蓋物及抗微生物組合物,該傷口覆蓋物係包含一碳質材料、一承載於該碳質材料之貴重 金屬、及一視需要選用之撓性基材層,其中該碳質材料係具粉末、顆粒、纖維、及/或薄片狀型態且選自以下群組:活性碳、石墨、碳、及其組合,且該貴重金屬係選自以下群組:銀、金、鈀、鉑、銅、鋅、及其組合;台灣專利(申請號098214538)為一種炭因子衛生棉,其中包含碳因子蕊片,該炭因子蕊片因為炭質緻密、比重大、孔隙多、礦物質含量豐富,能夠達到除濕去味、抑菌殺菌、消臭作用。以上二技術對於減少體表厭氧菌所使用的技術,多是器材本身具吸附細菌的功效,但細菌本身未被殺死且細菌生長沒有被抑制,會因為器材本身吸附菌量達到飽和而無法繼續吸附,。 Taiwan Patent (Application No. 095134585) is a wound covering and an antimicrobial composition comprising a carbonaceous material and a valuable bearing on the carbonaceous material. a metal, and a flexible substrate layer as desired, wherein the carbonaceous material is in the form of a powder, granule, fiber, and/or flake and is selected from the group consisting of activated carbon, graphite, carbon, and Combining, and the precious metal is selected from the group consisting of silver, gold, palladium, platinum, copper, zinc, and combinations thereof; the Taiwan patent (Application No. 098214538) is a carbon factor sanitary napkin containing a carbon factor chip, The charcoal factor chip can achieve dehumidification, bacteriostatic, deodorizing effect because of its compact carbon, large specific gravity, abundant pores and rich mineral content. The above two techniques are used to reduce the surface anaerobic bacteria, and the equipment itself has the effect of adsorbing bacteria. However, the bacteria itself is not killed and the growth of the bacteria is not inhibited, and the amount of bacteria adsorbed by the equipment itself cannot be saturated. Continue to adsorb.

台灣專利(申請號103115497),為抗微生物之組合物及其製造方法,包含用包含銀化合物以賦予抗微生物特性之組成物處理醫學及非醫學裝置及製品。此技術是以銀化合物為殺菌劑殺死微生物,但使用殺菌劑會導致細菌的抗藥性,而衍生更嚴重的健康危害。 Taiwan Patent (Application No. 103115497), which is an antimicrobial composition and a method of producing the same, comprises treating medical and non-medical devices and articles with a composition comprising a silver compound to impart antimicrobial properties. This technology kills microorganisms with silver compounds as fungicides, but the use of fungicides can lead to bacterial resistance and lead to more serious health hazards.

針對傷口部位因為缺氧導致厭氧菌感染而延遲傷口癒合,目前的治療方法為利用高壓氧、或氧氣瓶等可為傷口提供氧氣的設備,但這些供氧設備昂貴且笨重,非大眾可以輕易接觸或隨身攜帶,如何提供一便宜且容易攜帶的可提供氧源設備即為大眾所關心的議題。 Delaying wound healing due to anaerobic infection caused by hypoxia, the current treatment method is to use oxygen or oxygen cylinders to supply oxygen to the wound, but these oxygen supply equipment is expensive and cumbersome, and can be easily used by the public. Contact or carry around, how to provide a cheap and easy to carry oxygen source equipment is a matter of public concern.

日本專利(JPA 2004536010)揭露一種化學氧氣發生器,其產生氧氣化學物質包含鹼土金屬(尤其是LiClO4、LiClO3、NaClO4、NaClO3、KClO4、KClO3)、過氧化物(尤其是Na2O2、K2O2)、超氧化物(尤其是KO2、NaO2);台灣專利(申請號083206076)為一種具有氧氣再生罐之面罩,其中該氧氣再生罐中包含過氧化鈉可以生成氧氣。以上二技術雖可以供給氧氣以攜帶,但體積龐大且笨重,只適合用於潛水等特定場合,非日常生活可以 隨身攜帶。 Japanese Patent (JPA 2004536010) discloses a chemical oxygen generator which produces oxygen chemistry including alkaline earth metals (especially LiClO 4 , LiClO 3 , NaClO 4 , NaClO 3 , KClO 4 , KClO 3 ), peroxides (especially Na 2 O 2 , K 2 O 2 ), superoxide (especially KO 2 , NaO 2 ); Taiwan Patent (Application No. 083206076) is a mask having an oxygen regeneration tank, wherein the oxygen regeneration tank contains sodium peroxide. Generate oxygen. Although the above two technologies can supply oxygen for carrying, they are bulky and cumbersome, and are only suitable for specific occasions such as diving, and can be carried around in daily life.

台灣專利(申請號104201257)為本案發明人之創作,一種具有供給氧氣與除濕功能之透氣材質口罩,係以過氧化金屬或超氧化金屬放置於口罩中,結合呼吸產生的水氣而生成氧氣,可以改善口罩內空氣品質;此技術輕便可以隨身攜帶,但產生氧氣的速度慢,無法於短時間內供給大量氧氣。 The Taiwan patent (Application No. 104201257) is the creation of the inventor of the present invention. A breathable material mask with oxygen supply and dehumidification function is placed in a mask with a metal peroxide or a super-oxidized metal, and generates oxygen by combining the moisture generated by the breathing. It can improve the air quality inside the mask; this technology can be carried around with ease, but the oxygen is generated slowly and cannot supply a large amount of oxygen in a short time.

綜合前述研究,雖然目前已經具有降低體表厭氧菌及提升局部氧氣含量的技術,但現有技術仍有不足之處,該不足之處包括:氧氣生成罐的體積龐大不易隨身攜帶、供氧口罩因為面積小,供氧源少,氧氣的生成速度慢,因此如何開發出一種可局部快速產生氧氣組合物,即成為本發明在此欲解決的一重要課題。 In summary of the foregoing research, although there are currently techniques for reducing surface anaerobic bacteria and increasing local oxygen content, the prior art still has deficiencies, including: the bulk of the oxygen generating tank is not easy to carry around, the oxygen mask Since the area is small, the oxygen supply source is small, and the oxygen generation rate is slow, how to develop a locally rapid oxygen generating composition is an important subject to be solved by the present invention.

鑒於前述之問題與缺失,發明人深思熟慮,以多年之經驗累積,經過長久的構思與研究,本發明目的在於提供一種可快速局部供氧組合物,以過氧化物為供氧源,利用皮膚汗腺排汗及傷口體液、血液的揮發,形成氫氧化物及氧氣,並搭配以催化劑增加氧氣生產速度,得以在短時間內大量產生氧氣,使小環境中有高純度氧氣保護受傷區域,抑制厭氧菌的繁殖,對於傷口癒合及衛生保健都有很大幫助。 In view of the foregoing problems and deficiencies, the inventors have deliberately and accumulated with years of experience. After long-term conception and research, the present invention aims to provide a rapid local oxygen supply composition using peroxide as an oxygen source and utilizing skin sweat glands. Perspiration and wound body fluid, blood volatilization, formation of hydroxide and oxygen, and with the catalyst to increase the oxygen production rate, can generate a large amount of oxygen in a short time, so that high-purity oxygen in the small environment protects the injured area and inhibits anaerobic The reproduction of bacteria is very helpful for wound healing and health care.

本發明的目的在於提供一種可局部快速產生氧氣組合物,該組合物包含供氧源與過氧化物酶,該供氧源係選自於由過氧化物和超氧化物所組成的群組。 It is an object of the present invention to provide a locally rapid oxygen generating composition comprising an oxygen source and a peroxidase selected from the group consisting of peroxides and superoxides.

為達前述發明目的,該供氧源與該過氧化物酶之重量比例為 50:1~1000:1。 For the purpose of the foregoing invention, the weight ratio of the oxygen supply source to the peroxidase is 50:1~1000:1.

為達前述發明目的,該供氧源與該過氧化物酶之較佳重量比例為100:1~500:1。 For the purpose of the foregoing invention, a preferred weight ratio of the oxygen source to the peroxidase is from 100:1 to 500:1.

為達前述發明目的,該過氧化物係選自於由過氧化鎂、過氧化鈣、過氧化鈉、過氧化鉀和過氧化鋰所組成的群組。 For the purpose of the foregoing invention, the peroxide is selected from the group consisting of magnesium peroxide, calcium peroxide, sodium peroxide, potassium peroxide, and lithium peroxide.

為達前述發明目的,該超氧化物係選自於由超氧化鎂、超氧化鈣、超氧化鈉、超氧化鉀和超氧化鋰所組成的群組。 For the purpose of the foregoing invention, the superoxide is selected from the group consisting of magnesium superoxide, calcium superoxide, sodium superoxide, potassium superoxide and lithium superoxide.

為達前述發明目的,該供氧源為顆粒狀或粉末狀。 For the purpose of the foregoing invention, the oxygen supply source is in the form of granules or powder.

為達前述發明目的,該過氧化物酶為顆粒狀或粉末狀。 For the purpose of the foregoing invention, the peroxidase is in the form of granules or powder.

為達前述發明目的,該過氧化物酶係為過氧化氫酶。 For the purposes of the foregoing invention, the peroxidase is catalase.

為達前述發明目的,該組合物可以用於與人體接觸的器材中,以抑制厭氧菌生長。 For the purposes of the foregoing invention, the composition can be used in equipment that comes into contact with the human body to inhibit the growth of anaerobic bacteria.

為達前述發明目的,該與人體接觸的器材包含OK繃、傷口敷料、衛生棉、衛生棉條、護墊、尿布、醫用尿墊、眼罩、耳罩、口罩、安全帽內襯墊。 For the purpose of the foregoing invention, the device in contact with the human body comprises an OK stretch, a wound dressing, a sanitary napkin, a tampon, a pad, a diaper, a medical pad, an eye mask, an earmuff, a mask, and a safety cap inner liner.

本發明之另一目的為提供一種可以抑菌的傷口敷料,該傷口敷料包含請求項1~10所述之組合物,該傷口敷料係利用快速產生氧氣達到抑菌效果。 Another object of the present invention is to provide a bacteriostatic wound dressing comprising the composition of claims 1 to 10 which utilizes rapid oxygen production to achieve a bacteriostatic effect.

本發明之另一目的為提供一種可以抑菌的衛生棉(條),該衛生棉(條)包含請求項1~10所述之組合物,該衛生棉(條)係利用快速產生氧氣達到抑菌效果。 Another object of the present invention is to provide a sterilizable sanitary napkin (strip) comprising the composition according to any one of claims 1 to 10, wherein the sanitary napkin (strip) utilizes rapid production of oxygen to suppress Bacterial effect.

1‧‧‧水 1‧‧‧ water

2‧‧‧抑菌組合物 2‧‧‧Antibacterial composition

201‧‧‧供氧源 201‧‧‧Oxygen source

202‧‧‧過氧化物酶 202‧‧‧Peroxidase

3‧‧‧傷口敷料 3‧‧‧Wound dressings

4‧‧‧衛生棉 4‧‧‧Sanitary cotton

5‧‧‧護墊 5‧‧‧ pads

6‧‧‧尿布 6‧‧‧ diapers

7‧‧‧眼罩 7‧‧‧ eye mask

第1圖(左)係為本發明之示意圖,以顯示過氧化物遇水產生氧氣。 Figure 1 (left) is a schematic representation of the invention to show that peroxide produces oxygen in contact with water.

第1圖(右)係為本發明之示意圖,以顯示過氧化物合併使用催化劑,遇水可以產生大量氧氣。 Figure 1 (right) is a schematic representation of the invention to show that the peroxide is combined with a catalyst which produces a significant amount of oxygen when exposed to water.

第2圖係為本發明一較佳實施例之使用示意圖,以顯示此可局部快速產生氧氣組合物用於傷口敷料之態樣。 Figure 2 is a schematic illustration of the use of a preferred embodiment of the invention to demonstrate the localized rapid production of an oxygen composition for use in a wound dressing.

第3圖係為本發明一較佳實施例之使用示意圖,以顯示此可局部快速產生氧氣組合物用於衛生棉、護墊之態樣。 Figure 3 is a schematic view of the use of a preferred embodiment of the present invention to show that the oxygen composition can be locally produced rapidly for use in sanitary napkins and pads.

第4圖係為本發明一較佳實施例之使用示意圖,以顯示此可局部快速產生氧氣組合物用於尿布之態樣。 Figure 4 is a schematic illustration of the use of a preferred embodiment of the invention to demonstrate the localized rapid production of an oxygen composition for use in a diaper.

第5圖係為本發明一較佳實施例之使用示意圖,以顯示此可局部快速產生氧氣組合物用於眼罩之態樣。 Figure 5 is a schematic illustration of the use of a preferred embodiment of the invention to show that the oxygen composition can be locally produced rapidly for use in an eye mask.

本發明係以下面的實施例予以示範闡明,但本發明不受下述實施例所限制。 The present invention is exemplified by the following examples, but the present invention is not limited by the following examples.

本發明是一種可局部快速產生氧氣組合物(2),參照第一圖所示,該組合物包含供氧源(201)與過氧化物酶(202),該供氧源(201)係選自於由過氧化物和超氧化物所組成的群組,供氧源與水(1)反應產生氧氣,供氧源(201)合併使用過氧化物酶(202)與水反應產生大量氧氣(如第一圖右所示);該組合物(2)可以用於傷口敷料(3)、衛生棉(4)、護墊(5)、尿布(6)、眼罩(7)等與人體接觸的器材上,使小環境中氧氣含量快速且大量增加,以抑制微生物生長。 The present invention is a locally rapid oxygen generating composition (2). As shown in the first figure, the composition comprises an oxygen source (201) and a peroxidase (202). The oxygen source (201) is selected. From the group consisting of peroxides and superoxides, the oxygen source reacts with water (1) to produce oxygen, and the oxygen source (201) is combined with peroxidase (202) to react with water to produce a large amount of oxygen ( As shown in the right figure of the first figure); the composition (2) can be used for contact with a human body such as a wound dressing (3), a sanitary napkin (4), a pad (5), a diaper (6), an eye mask (7), and the like. On the equipment, the oxygen content in the small environment is rapidly and greatly increased to inhibit the growth of microorganisms.

實施例1 Example 1

過氧化鉀(K2O2)遇水產生氧氣的化學反應 Chemical reaction of potassium peroxide (K 2 O 2 ) to produce oxygen in water

2K2O2+2H2O→4KOH+2H2O2 2K 2 O 2 +2H 2 O→4KOH+2H 2 O 2

2H2O2→2H2O+O2 2H 2 O 2 →2H 2 O+O 2

過氧化物如過氧化鉀(K2O2)遇水(H2O)產生氫氧化鉀(KOH)與過氧化氫(H2O2),過氧化氫會進一步生成水與氧氣(O2),如第1圖(左)所示。 Peroxides such as potassium peroxide (K 2 O 2 ) produce potassium hydroxide (KOH) and hydrogen peroxide (H 2 O 2 ) in the presence of water (H 2 O), which further produces water and oxygen (O 2 ). ), as shown in Figure 1 (left).

實施例2 Example 2

過氧化鉀合併使用過氧化氫酶(Catalase,簡稱CAT)遇水快速產生氧氣的化學反應 Potassium peroxide combined with catalase (CAT) for rapid chemical reaction with water

2K2O2+2H2O→4KOH+2H2O2 2K 2 O 2 +2H 2 O→4KOH+2H 2 O 2

過氧化物如過氧化鉀遇水產生氫氧化鉀與過氧化氫,過氧化氫酶(Catalase,簡稱CAT)使過氧化氫快速生成水與氧氣,如第1圖(右)所示,與未合併使用過氧化氫酶相比,可於短時間內累積大量氧氣。 Peroxide such as potassium peroxide in the presence of water produces potassium hydroxide and hydrogen peroxide, and catalase (CAT) causes hydrogen peroxide to rapidly form water and oxygen, as shown in Figure 1 (right). A large amount of oxygen can be accumulated in a short time compared to the combined use of catalase.

實施例3 Example 3

超氧化鈉(NaO2)遇水產生氧氣的化學反應 Chemical reaction of sodium superoxide (NaO 2 ) to produce oxygen in water

2NaO2+4H2O→2NaOH+3H2O2 2NaO 2 +4H 2 O→2NaOH+3H 2 O 2

H2O2→2H2O+O2 H 2 O 2 →2H 2 O+O 2

超氧化物如超氧化鈉(NaO2)遇水產生氫氧化鈉(NaOH)與過氧化氫,過氧化氫會進一步生成水與氧氣,如第1圖(左)所示。 Superoxides such as sodium superoxide (NaO 2 ) produce sodium hydroxide (NaOH) and hydrogen peroxide in contact with water. Hydrogen peroxide further produces water and oxygen, as shown in Figure 1 (left).

實施例4 Example 4

超氧化物超氧化鈉合併使用過氧化氫酶遇水快速產生氧氣 的化學反應 Superoxide superoxide combined with hydrogen peroxide to rapidly produce oxygen in contact with water Chemical reaction

2NaO2+4H2O→2NaOH+3H2O2 2NaO 2 +4H 2 O→2NaOH+3H 2 O 2

超氧化鈉遇水產生氫氧化鈉與過氧化氫,過氧化氫酶使過氧化氫快速生成水與氧氣,如第1圖(右)所示,與未合併使用過氧化氫酶相比,可於短時間內累積大量氧氣。 Superoxide sodium produces sodium hydroxide and hydrogen peroxide in contact with water. Hydrogenase rapidly produces hydrogen and oxygen by hydrogen peroxide, as shown in Figure 1 (right), compared with non-combined catalase. A large amount of oxygen is accumulated in a short time.

實施例5 Example 5

傷口敷料添加過氧化物合併使用過氧化物酶之抑菌功效 Addition of peroxide to wound dressing combined with the antibacterial effect of peroxidase

傷口敷料中含有抑菌組合物包含過氧化物(如過氧化鎂)與過氧化物酶(如過氧化氫酶),過氧化物與過氧化氫酶的重量比例可為50:1~1000:1,過氧化物與過氧化氫酶的重量比例最佳為100:1~500:1;如第二圖所示,該含抑菌組合物傷口敷料接觸傷口,遇上汗液、體液、血液或其他水源,會快速、大量生成氧氣,厭氧菌因為對氧氣的耐受力低,因此可抑制傷口處厭氧菌的生長,該厭氧菌包含專性厭氧菌與兼性厭氧菌。 The wound dressing contains a bacteriostatic composition comprising a peroxide (such as magnesium peroxide) and a peroxidase (such as catalase), and the weight ratio of peroxide to catalase can be 50:1~1000: 1, the weight ratio of peroxide to catalase is preferably 100:1~500:1; as shown in the second figure, the bacteriostatic composition wound dressing contacts the wound and encounters sweat, body fluid, blood or Other water sources produce oxygen quickly and in large quantities. Anaerobic bacteria can inhibit the growth of anaerobic bacteria in the wound because of their low tolerance to oxygen. The anaerobic bacteria contain obligate anaerobic bacteria and facultative anaerobic bacteria.

實施例6 Example 6

衛生棉(條)添加過氧化物合併使用過氧化物酶之抑菌功效 Hygienic cotton (strip) added peroxide combined with the antibacterial effect of peroxidase

衛生棉(條)中含有抑菌組合物包含過氧化物(如過氧化鈣)與過氧化物酶(如過氧化氫酶),過氧化物與過氧化氫酶的重量比例可為50:1~1000:1,過氧化物與過氧化氫酶的重量比例最佳為100:1~500:1;如第三圖所示,該含抑菌組合物衛生棉(條)接觸外陰部,遇上汗液、體液、血液或其他水源,會快速、大量生成氧氣,酵母菌等厭氧菌因為對氧氣的耐受力低,因此可抑制外陰部厭氧菌的生長,該厭氧菌包含專性厭氧菌與兼性 厭氧菌。 The sanitary cotton (strip) contains a bacteriostatic composition comprising a peroxide (such as calcium peroxide) and a peroxidase (such as catalase), and the weight ratio of peroxide to catalase can be 50:1. ~1000:1, the weight ratio of peroxide to catalase is preferably 100:1~500:1; as shown in the third figure, the bacteriostatic cotton containing the bacteriostatic composition contacts the genital area. On sweat, body fluids, blood or other water sources, oxygen is rapidly and massively produced. Anaerobic bacteria such as yeast can inhibit the growth of anaerobic bacteria in the vulva because of its low tolerance to oxygen. The anaerobic bacteria contain specificity. Anaerobic bacteria and facultative Anaerobic bacteria.

實施例7 Example 7

口罩添加過氧化物合併使用過氧化物酶對人體沒有刺激性 Masks add peroxide and use peroxidase is not irritating to human body

口罩中含有抑菌組合物包含過氧化物(如過氧化鉀)與過氧化物酶(如過氧化氫酶),過氧化物與過氧化氫酶的重量比例可為50:1~1000:1,過氧化物與過氧化氫酶的重量比例最佳為100:1~500:1;該含抑菌組合物口罩接觸汗液、體液、血液、呼吸產生之水氣或其他水源,會快速、大量生成氧氣,2K2O2+2H2O→4KOH+2H2O2 The mask contains a bacteriostatic composition comprising a peroxide (such as potassium peroxide) and a peroxidase (such as catalase), and the weight ratio of peroxide to catalase can be 50:1~1000:1. The weight ratio of peroxide to catalase is preferably 100:1~500:1; the mask containing the antibacterial composition is in contact with sweat, body fluid, blood, water or other water source generated by breathing, and will be quickly and massively Oxygen generation, 2K 2 O 2 +2H 2 O→4KOH+2H 2 O 2

其中過氧化鉀遇水會生氧氣,其中間產物為過氧化氫,抑制組合物中的過氧化氫酶,可以將過氧化氫快速轉化為水及氧氣,因此過氧化氫不會累積於口罩中,對人體造成刺激性。 Among them, potassium peroxide generates oxygen when it is in contact with water, and the intermediate product is hydrogen peroxide, which inhibits the catalase in the composition, and can rapidly convert hydrogen peroxide into water and oxygen, so hydrogen peroxide does not accumulate in the mask. , causing irritation to the human body.

本發明提供一種可局部快速產生氧氣組合物,以過氧化氫酶催化過氧化物生成氧氣的反應,使氧氣可在短時間內大量產生;在小環境中累積大量氧氣,可以進一步抑制厭氧菌的生長;過氧化氫為過氧化物生成氧氣的中間產物,但對人體有刺激性,本發明利用過氧化氫酶催化過氧化物生成氧氣的反應,使中間產物過氧化氫部會累積,降低對人體的刺激性;本發明非以吸附或以藥物殺菌,不會造成抗藥性,且輕便方便隨身攜帶,解決了先前技術中無法達成的問題。 The invention provides a method for locally and rapidly generating an oxygen composition, wherein a hydrogen peroxide enzyme catalyzes a peroxide to generate oxygen, so that oxygen can be produced in a short time; and a large amount of oxygen is accumulated in a small environment to further inhibit anaerobic bacteria. The growth of hydrogen peroxide is an intermediate of oxygen generation by peroxide, but it is irritating to human body. The present invention utilizes catalase to catalyze the reaction of peroxide to generate oxygen, so that the hydrogen peroxide portion of the intermediate product will accumulate and decrease. Irritating to the human body; the invention is not absorbing or sterilizing by drugs, does not cause drug resistance, and is light and convenient to carry around, solving the problems that cannot be achieved in the prior art.

上列詳細說明係針對本發明之可行實施例之具體說明,惟該實施例並非用以限制本發明之專利範圍,凡未脫離本發明技藝精神所為之 等效實施或變更,均應包含於本案之專利範圍中。 The detailed description above is a detailed description of the possible embodiments of the present invention, and is not intended to limit the scope of the invention, which is not to be Equivalent implementations or changes shall be included in the scope of the patent in this case.

上述多項功效,實屬充分符合新穎性及進步性之法定專利要件,爰依法提出申請,懇請 貴局核准本件發明專利申請案,以勵發明。 The above-mentioned multiple functions are the statutory patent requirements that fully meet the novelty and progressiveness. If you apply in accordance with the law, you are requested to approve the application for the invention patent to encourage the invention.

1‧‧‧水 1‧‧‧ water

201‧‧‧供氧源 201‧‧‧Oxygen source

202‧‧‧過氧化物酶 202‧‧‧Peroxidase

Claims (12)

一種可局部快速產生氧氣組合物,該組合物包含供氧源與過氧化物酶,該供氧源係選自於由過氧化物和超氧化物所組成的群組。 A locally rapid oxygen generating composition comprising an oxygen source and a peroxidase selected from the group consisting of peroxides and superoxides. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該供氧源與該過氧化物酶之重量比例為50:1~1000:1。 A locally rapid oxygen generating composition according to claim 1, wherein the ratio of the oxygen source to the peroxidase is from 50:1 to 1000:1. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該供氧源與該過氧化物酶之較佳重量比例為100:1~500:1。 A locally rapid oxygen generating composition as described in claim 1, wherein the preferred ratio of the oxygen source to the peroxidase is from 100:1 to 500:1. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該過氧化物係選自於由過氧化鎂、過氧化鈣、過氧化鈉、過氧化鉀和過氧化鋰所組成的群組。 A locally rapid oxygen generating composition according to claim 1, wherein the peroxide is selected from the group consisting of magnesium peroxide, calcium peroxide, sodium peroxide, potassium peroxide and lithium peroxide. Group. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該超氧化物係選自於由超氧化鎂、超氧化鈣、超氧化鈉、超氧化鉀和超氧化鋰所組成的群組。 A locally rapid oxygen generating composition according to claim 1, wherein the superoxide is selected from the group consisting of magnesium superoxide, calcium superoxide, sodium superoxide, potassium superoxide and lithium superoxide. Group. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該供氧源為顆粒狀或粉末狀。 A locally rapid oxygen generating composition as described in claim 1, wherein the oxygen supply source is in the form of granules or powder. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該過氧化物酶為顆粒狀或粉末狀。 A partially rapid oxygen generating composition as described in claim 1, wherein the peroxidase is in the form of granules or powder. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該過氧化物酶係為過氧化氫酶。 A locally rapid oxygen generating composition as described in claim 1, wherein the peroxidase is a catalase. 如申請專利範圍第1項所述之一種可局部快速產生氧氣組合物,該組合物可以用於與人體接觸的器材中,具有抑制厭氧菌生長的效果。 A locally rapid oxygen generating composition as described in claim 1, wherein the composition can be used in a device in contact with a human body to have an effect of inhibiting the growth of anaerobic bacteria. 如申請專利範圍第9項所述之一種可局部快速產生氧氣組合物,該與人體接觸的器材包含OK繃、傷口敷料、衛生棉、衛生棉條、護墊、尿布、醫用尿墊、眼罩、耳罩、口罩、安全帽內襯墊。 A locally rapid oxygen generating composition according to claim 9, wherein the human contact device comprises an OK stretch, a wound dressing, a sanitary napkin, a tampon, a pad, a diaper, a medical pad, and an eye mask. , earmuffs, masks, inner cushions for hard hats. 一種可以抑菌的傷口敷料,該傷口敷料包含請求項1~10所述之組合物,該傷口敷料係利用快速產生氧氣達到抑菌效果。 A bacteriostatic wound dressing comprising the composition of claims 1 to 10, wherein the wound dressing utilizes rapid production of oxygen to achieve a bacteriostatic effect. 一種可以抑菌的衛生棉(條),該衛生棉(條)包含請求項1~10所述之組合物,該衛生棉(條)係利用快速產生氧氣達到抑菌效果。 A sterilizable sanitary napkin (strip) comprising the composition according to any one of claims 1 to 10, wherein the sanitary napkin (strip) utilizes rapid production of oxygen to achieve a bacteriostatic effect.
TW105105069A 2016-02-22 2016-02-22 A composition capable of fast locally producing oxygen which uses the peroxide as the oxygen-supplying source, which is selected from groups of the peroxide and superoxide TW201730100A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI681783B (en) * 2017-09-29 2020-01-11 曹榮華 Hygiene supplies for carbon dioxide gas
WO2021208060A1 (en) * 2020-04-17 2021-10-21 咏达生医材料股份有限公司 Gas supply device, use thereof for lightening hair color and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI681783B (en) * 2017-09-29 2020-01-11 曹榮華 Hygiene supplies for carbon dioxide gas
WO2021208060A1 (en) * 2020-04-17 2021-10-21 咏达生医材料股份有限公司 Gas supply device, use thereof for lightening hair color and method

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