TW200814927A - Active compound combinations having insecticidal and acaricidal properties - Google Patents

Abstract

The present invention relates to novel active compound combinations comprising firstly at least one known compound of the formula (I), in which R is as defined in the description, and secondly at least one further known active compound from the class of the pyrethroids, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids.

Description

200814927 九、發明說明： 【發明所屬之技術領域】 本發明關於新穎的活性化合物組合物，係包含，首 先，至少一種已知之具式（I)的化合物，以及其次，至少一 種另一類的來自擬除蟲菊酯類(pyrethroids)的化合物，這 樣的組合物為高度地適於供防治動物有害生物，例如昆蟲 以及不想要的蟎類。 【先前技術】 已知，具式(I)的化合物 15200814927 IX. DESCRIPTION OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates to novel active compound compositions comprising, firstly, at least one compound of formula (I) known, and secondly, at least one other class Compounds of pyrethroids, such compositions are highly suitable for controlling animal pests, such as insects and unwanted mites. [Prior Art] Compounds of formula (I) are known.

NN

N—RN-R

CI (I) 其中 R 代表甲基或環丙基 具有殺昆蟲的活性（參考：ΕΡ-Α 0 539 588)，明確地說，相 關的化合物可能為化合物（la)及(lb): 20 (la):CI (I) wherein R represents a methyl or cyclopropyl group having insecticidal activity (Reference: ΕΡ-Α 0 539 588), specifically, the relevant compound may be compound (la) and (lb): 20 (la) ):

NN

CICI

N——CH. (la) -6- 200814927 (lb) ·· (lb)N——CH. (la) -6- 200814927 (lb) ·· (lb)

1010

【發明内容】 此外，已知某些來自擬除蟲菊S旨類（pyrethroids)的化 合物具有殺昆蟲及殺蟎的性質，目前已發現，併用至少一 種式（I)的化合物及至少一種挑選自包括下類的化合物： 1.阿納寧（acrinathrin)SUMMARY OF THE INVENTION Furthermore, it is known that certain compounds from pyrethroids have insecticidal and acaricidal properties, and it has now been found that at least one compound of formula (I) and at least one selected from Includes the following classes of compounds: 1. Aninin (acrinathrin)

1515

得知自:EP_A-048 186， 2. α-賽滅寧（alpha-cypermethrin)Learned from: EP_A-048 186, 2. alpha-cypermethin

200814927 得知自：EP-A-067 461， 3 · β-賽扶寧(betacyfluthrin)200814927 Learned from: EP-A-067 461, 3 · β-赛康宁 (betacyfluthrin)

得知自：EP-A-206 149， ίο 4. γ_ 赛洛寧（gamma-cyhalothrin)Learned from: EP-A-206 149, ίο 4. γ_ 赛马宁 (gamma-cyhalothrin)

得知自：DE-A-2 802 962， 5.賽滅寧(cypermethrin)Learned from: DE-A-2 802 962, 5. Cypermethrin

〇 CN〇 CN

得知自：DE-A-2 326 077， 6.第滅寧(deltamethrin) 20 200814927Learned from: DE-A-2 326 077, 6. Detamethrin 20 200814927

10 得知自：DE-A-2 326 077， 益化利（esfenvalerate)10 Learned from: DE-A-2 326 077, esfenvalerate

1515

得知自：DE-A-2 737 297， 8.依芬寧（ethofenprox)Learned from: DE-A-2 737 297, 8. Efenning (ethofenprox)

得知自：DE-A-3 117 510， 9.芬普寧（fenpropathrin) 20Learned from: DE-A-3 117 510, 9. Fenpropathin 20

得知自：DE-A-2 231 312， -9- 200814927 10.氰戊菊酯(fenvalerate)Learned from: DE-A-2 231 312, -9- 200814927 10. Fenvalerate

10 得知自：DE-A-2 335 347， 11·護賽寧（flucythrinate)10 Learned from: DE-A-2 335 347, 11·flucythrinate

得知自：DE-A-2 757 066， 15Learned from: DE-A-2 757 066, 15

12. λ-赛洛寧(lambda-cyhalothrin) 2012. λ-赛洛宁 (lambda-cyhalothrin) 20

得知自：EP-A-106 469， 13.百滅寧（permethrin) -10- 200814927Learned from: EP-A-106 469, 13. Permethrin -10- 200814927

得知自：DE-A-2 326 077， 14.套福化利（taufluvalinate)Learned from: DE-A-2 326 077, 14. Fortune (taufluvalinate)

1010

得知自：EP-A-038 617， 15.泰滅寧(tralomethrin) 15Learned from: EP-A-038 617, 15. Tralomethrin 15

得知自：DE-A-2 742 546， 16、zeta-賽滅寧(zeta-cypermethrin) 20Learned from: DE-A-2 742 546, 16, zeta-cypermethrin 20

200814927 得知自：EP-A-026 542， 17.賽扶寧（cy fluthrin)200814927 Learned from: EP-A-026 542, 17. cy fluthrin

55

10 得知自：DE-A-27 09 264， 18.畢芬寧(bifenthrin)10 Learned from: DE-A-27 09 264, 18. Bifenthrin

得知自：EP-A-049 977， 19.環普寧（cycloprothrin) 15Learned from: EP-A-049 977, 19. cycloprothrin 15

得知自：DE-A-2653189， 20·伊伏砍連特（eflusilanate) 20 200814927Learned from: DE-A-2653189, 20·eflusilanate 20 200814927

5 得知自：DE-A-36 04 781， 21 ·福芬普（fubfenprox)5 Learned from: DE-A-36 04 781, 21 · Fuffenprox

1010

得知自：DE-A-37 08 231， 22.除蟲菊精(pyrethrin) 15Learned from: DE-A-37 08 231, 22. Pyrethrin (pyrethrin) 15

20 R = -CH3 或-C02CH3 11版，第 R! —CH=CH2 或《CH3 或-ch2ch3 得知自：The Pesticide Manual，1997，第 1056 頁， 23.列滅寧(resmethrin) -13- 20081492720 R = -CH3 or -C02CH3 version 11, R! -CH=CH2 or "CH3 or -ch2ch3 learned from: The Pesticide Manual, 1997, p. 1056, 23. Resmethrin -13- 200814927

得知自：GB-A] 168 797， 以及 24.七氟菊酯（tefluthrin)Learned from: GB-A] 168 797, and 24. Tefluthrin

F CH0 得知自：EP-A1 31 199， 15 20 所產生之組合物為具有協乘地活性物且適於供防治 動物有害生物，令人驚訝地，根據本發明的活性化合物組 合物之殺昆蟲的及殺蟎的活性較其中個別活性化合物之 活性的和要南得多^存在者一種未被預期到的真貫的協乘 性效果，且非僅僅是活性的相加值。 除了至少一種具式(I)之活性化合物外，根據本發明的 活性化合物組合物包含至少一種被個別地列於上述之1至 24種的擬除蟲菊酯類(pyrethroids)。 較佳地，根據本發明的活性化合物組合物包含式（la) -14- 200814927 或（lb)之一的活性化合物以及被個別地列於上面之1至24 種的擬除蟲菊酯類之一。 被列於表1中之組合物係根據本發明之較佳的具體實 施例。 表1F CH0 is known from: EP-A1 31 199, 15 20 The composition produced is a synergistic active and suitable for controlling animal pests, surprisingly, the active compound composition according to the invention is killed The insect and acaricidal activity is much greater than the sum of the activities of the individual active compounds. There is an unanticipated true synergistic effect, and not just the additive value of the activity. In addition to at least one active compound of the formula (I), the active compound composition according to the invention comprises at least one pyrethroids which are individually listed in the above 1 to 24 species. Preferably, the active compound composition according to the invention comprises an active compound of one of formula (la)-14-200814927 or (lb) and from 1 to 24 pyrethroids individually listed above. One. The compositions listed in Table 1 are in accordance with preferred embodiments of the present invention. Table 1

混合物包含 式(I)的化合物 擬除蟲菊酯類 1. Ia 及 1 阿納寧(acrinathrin) 2. la 及 2 α-賽滅寧(alpha-cypermethrin) 3. Ia 及 3 β-賽扶寧(betacyfluthrin) 4. Ia 及 4 γ-賽洛寧(gamma-cyhalothrin) 5· Ia 及 5 赛滅寧(cypermetMn) 6. la 及 6 第滅寧(deltamethrin) 7. la 及 7 益化利(esfenvalerate) 8. Ia 及 8 依芬寧(ethofenprox) 9. la 及 9 芬普寧(fenpropatMn) 10. la 及 10 氰戊菊酯(fenvalerate) 11. Ia 及 11 護賽寧(flucythrinate) 12. Ia 及 12 λ-赛洛寧(lambda-cyhalothrin) 13. Ia 及 13 百滅寧(permethrin) 14. Ia 及 14 套福化利(taufluvalinate) 15. Ia 及 15 泰滅寧(tralomethrin) 16. la 及 16 (zeta-賽滅寧)(zeta-cypermethrin) -15- 200814927 17. Ia 及 17 賽扶寧(cy fluthrin) 18. la 及 18 畢芬寧(bifenthrin) 19. la 及 19 環普寧(cycloprothrin) 20. Ia 及 20 伊伏碎連特(eflusilanate) 21. Ia 及 21 福芬普(fiibfenprox) 22. la 及 22 除蟲菊精(pyrethrin) 23. Ia 及 23 列滅寧(resmethrin) 24. Ia 及 24 七氟菊醋(tefluthrin) 此外，被列於表2中之組合物也是根據本發明之較佳 的具體實施例。 5 表2The mixture comprises the compound pyrethroids of formula (I) 1. Ia and 1 arrinathrin 2. la and 2 α-cypermethrin 3. Ia and 3 β-saiconin ( Betacyfluthrin) 4. Ia and 4 gamma-cyhalothrin 5· Ia and 5 cypermetMn 6. la and 6 deltamethrin 7. la and 7 esfenvalerate 8. Ia and 8 etfinenprox 9. la and 9 fenpropatMn 10. la and 10 fenvalerate 11. Ia and 11 flucythrinate 12. Ia and 12 λ - lambda-cyhalothrin 13. Ia and 13 permethrin 14. Ia and 14 sets of taufluvalinate 15. Ia and 15 tralmethrin 16. la and 16 (zeta -赛杀宁)(zeta-cypermethrin) -15- 200814927 17. Ia and 17 cy fluthrin 18. la and 18 bifenthrin 19. la and 19 cycloprothrin 20. Ia and 20 Eflusilanate 21. Ia and 21 fiiffenprox 22. la and 22 pyrethrin 23. Ia and 23 resmethrin 24. Ia and 24 tefluthrin In addition, the compositions listed in Table 2 are also preferred embodiments in accordance with the present invention. 5 Table 2

混合物包含 式（I)的化合物 擬除蟲菊酯類 1. lb 及 1 阿納寧（acdnathrin) 2. lb 及 2 α-賽滅寧（alpha-cypermethrin) 3. lb 及 3 β-賽扶寧（betacyfluthrin) 4. lb 及 4 γ-賽洛寧（gamma-cyhalothrin) 5. lb 及 5 賽滅寧（cypermethrin) 6· lb 及 6 第滅寧(deltamethrin) 7. lb 及 7 益化利（esfenvalerate) 8· lb 及 8 依芬寧（ethofenprox) 9' lb 及 9 芬普寧（fenpropathrin) -16- 200814927 10. Ib 及 1 〇 氰戊菊酯（fenvalerate) 11. lb 及 11 護賽寧（flucythrinate) 12. Ib 及 12 lambda-賽洛寧 (lambda-cyhalothrin) 13. Ib 及 13 百滅寧（permethrin) 14. Ib 及 14 套福化利（taufluvalinate) 15. Ib 及 15 泰滅寧(tralomethrin) 16. Ib 及 16 (zeta-賽滅寧） (zeta-cypermethriii) 17. Ib 及 17 賽扶寧（cyfluthrin) 18. Ib 及 18 畢芬寧（bifenthrin) 19. Ib 及 19 環普寧（cycloprothrin) 20. Ib 及 20伊伏石夕連特（eflusilanate) 21. Ib 及 21 福芬普（fubfenprox) 22. Ib 及 22 除蟲菊精(pyrethrin) 23. Ib 及 23 列滅寧(resmethrin) 24. Ib 及 24 七氟菊酯（tefluthrin) 此協乘性效果特別是在根據本發明的活性化合物組 合物中之活性化合物以某種重量比例存在下明顯存在，然 而，在活性化合物組合物中之活性化合物間之重量比例可 5 在相對地廣範圍内變化，通常，根據本發明包含式(I)的活 性化合物及1至24類的擬除蟲菊酯類之組合物的較佳的 及特別佳的混合比例為： -17- 200814927 較佳的混合比例： 125:1至1:125 特別佳的混合比例· 25:1至1:25 此混合比例係以重量比例為依據，此重量比例可理解 的係指式⑴的活性化合物：擬除蟲菊酯類。 5 本發明的活性化合物組合物，在組合下，植物對其有 很好的耐受性且其毒性有利於溫血的動物，且能讓環境忍 受得很好，而適於用供保護植物及植物器官、供增進收穫 | 量、用於改進收穫物之品質以及用於供控制有害生物，特 別是與農業、園藝、動物飼養、林業、花園及休閒設施、 10 儲存的產物及材料之保護、以及衛生領域中相關的昆蟲、 瞒類、蠕蟲、線蟲及軟體動物等，它們宜被應用作為一種 植物保護劑，它們有活性用於對抗正常的敏感性及有抗性 的物種，以及對抗其全部的或個別的發育階段，上述的有 害生物包括： 15 蝨目（Anoplura，Phthiraptera)生物，例如，羽蝨屬 鲁 （Damalinia spp·)，t 鉍M(Haematopinus spp.)，長韻蝨屬 ，虱蝨屬（Pediculus π/?·)，毛蝨屬The mixture comprises the compound pyrethroids of formula (I) 1. lb and 1 acdnathrin 2. lb and 2 α-cypermethrin 3. lb and 3 β-赛保宁 ( Betacyfluthrin) 4. lb and 4 gamma-cyhalothrin 5. lb and 5 cypermethrin 6· lb and 6 deltamethrin 7. lb and 7 esfenvalerate 8· lb and 8 etfinenprox 9' lb and 9 fenpropathrin -16- 200814927 10. Ib and 1 fenvalerate 11. lb and 11 flucythrinate 12 Ib and 12 lambda-cyhalothrin 13. Ib and 13 permethrin 14. Ib and 14 sets of taufluvalinate 15. Ib and 15 tralmethrin 16. Ib and 16 (zeta-cypermethiniii) 17. Ib and 17 cyfluthrin 18. Ib and 18 bifenthrin 19. Ib and 19 cycloprothrin 20. Ib and 20 Eflusilanate 21. Ib and 21 fubfenprox 22. Ib and 22 de-worming Pyrethrin 23. Ib and 23 resmethrin 24. Ib and 24 tefluthrin This synergistic effect is especially in the active compound composition according to the invention. The weight ratio is apparent in the presence of a weight ratio, however, the weight ratio between the active compounds in the active compound composition can vary within a relatively wide range. Generally, the active compounds of formula (I) and from 1 to 24 are included according to the invention. A preferred and particularly preferred mixing ratio of the pyrethroid-like composition is: -17- 200814927 Preferred mixing ratio: 125:1 to 1:125 Particularly good mixing ratio 25:1 to 1:25 This mixing ratio is based on the weight ratio, and the weight ratio is understood to mean the active compound of the formula (1): pyrethroids. 5 The active compound composition of the present invention, in combination, is well tolerated by plants and its toxicity is beneficial to warm-blooded animals, and can endure the environment well, and is suitable for protecting plants and Plant organs, for enhanced harvesting | quantity, for improving the quality of harvested materials and for controlling pests, especially with agriculture, horticulture, animal husbandry, forestry, gardens and leisure facilities, 10 storage of products and materials, And related insects, mites, worms, nematodes and mollusks in the health field, they should be used as a plant protection agent, they are active against normal sensitive and resistant species, and against them. For all or individual developmental stages, the above-mentioned pests include: 15 Anoplura (Phthiraptera) organisms, for example, Damalinia spp., t 铋M (Haematopinus spp.), Rhododendron spp. Genus (Pediculus π/?·), Ranunculus

(Trichodectes spp.) Q 蛛形綱（Arachnida)生物，例如，粗腳粉瞒 20 Wn?)，桔瘤節蜱 s/ze/i/ofn·)，刺皮趨蜗屬 印;?·），dcw/ws spp·，花蜱屬（Amblyomma 5即.），隱缘蜱屬 (Argas spp，牛缉屦（Boophilus 叹ρ·)，短鬚瞒屬 (Brevipalpus spp.)，售辖荖蛾（Bryobia praetiosa)，癢編屬 ，雞皮刺蜗(Derw㈣)，虫知蛛 -18- 200814927 5(Trichodectes spp.) Q Arachnida organisms, for example, 20 n 粗 ) , , 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 桔 ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Dcw/ws spp·, Amaranthus (Amblyomma 5), Argas spp, Boophilus (Spirit ρ·), Brevipalpus spp., Selling moth (Bryobia) Praetiosa), itch-like genus, chicken skin thorn (Derw (four)), worm-like spider -18- 200814927 5

10 1510 15

20 蜗屬（Eutetranychus spp·)，療蟎(Eriophyes spp.)，為害构 把的藤瞒（Eriophyes spp·)，Hemitarsonemus spp·，水蜱屬 (//ya/omwa π;?·)，硬蜱屬（Τχοί/α s/?;?·)，黑寡婦球腹蛛 [Latrodectus mactans)，$χΛ知KMetatetranychus spp·)，案 織（Oligonychus spp.)，洗緣缉屬（Ornithodoros spp·)， 蛛(Panonychus spp·)，結錄滿（Phyllocoptruta oleivora)，茶 黃蝶（Polyphagotarsonemus latus)，秦缉凰（Psoroptes spp·)，k 江 M 斗碑屬（Rhipicephalus spp·)，根織 (Rhizoglyphus spp·)，齋絲餍（Sarcoptes spp·)，歌子（Scorpio maurus)，Stenotarsonemus spp·，氣絡屬{Tarsonemus spp.)， $cl 葉編屬（Tetranychus spp·)，Vasates lycopersici。 雙殼綱（Bivalva)生物，例如， 唇足亞綱（Chilopoda)生物，例如，娱讼屬 spp·、，油敗M (Scutigera spp·、。 鞘翅目（Coleoptera)生物，例如，菜豆象 o&eciMS)，長金龜(yUoreiws 叹/7·)，揚樹 螢葉曱（dge/fl如cfl ，金針蟲叩曱（dgrbies s/τρ·)，馬龄 集聽金氣(Amphimallon solstitialis)，像倶藕蠢（Anobium punctatum)，I 天年（Anoplophora πρ·)，棉鈴象曱 (Anthonomus spp·)，皮蠢屬（Anthrenus spp.)，Μ 聽金象子 (Apogonia spp.)，隱食 f 饜（Atomaria spp.)，票、良蠢雁 {Attagenus spp)，l l {Bruchidius obtectus)，l I 爆 [Bruchus spp·)，1 氧 t{Ceuthorhyhchus spp·、，Cleonus -19- 200814927 mendicus，Conoderus spp·，H 鼻氣{Cosmopolites spp·、， ^%H{Cryptorhynchus lapathi)，l 蠢亀{Dermestes spp·、、 玉米根葉 Ψ (Diabrotica spp·)，豆瓢螽屬（Epiiachna spp·)， 5 瓢^XEpilachna spp·、，Faustinus cubae，裸或[Gibbium psylloides)，Heteronychus arator，Hylamorpha elegans， 北美家天牛〇Κ>/οίΓΜ；7α ，苜蓿葉象曱 postica)，咖 _ 果小蠹sp/7·)，靖槽 (Lachnostrna consanguinea)，科羅拉多金 H 義(Leptinotarsa ίο decemlineata)，檢木篆气{Lissorhoptrus oryzophilus)，l奏 蟲〇Lz·胤s spp·)，褐粉蠹屬（Lyctus spp·)，油菜花露尾曱 (Meligethes aeneus)，大栗無苒金氣（Melolontha melolontha)，天年{Migdolus spp)，欠年{Monochamus spp〇 5 ® S ^^(Naupactus xanthographus) 9 ψ (Niptus 15 hololeucus)，厍龟金氧{Oryctes rhinoceros)，锻各箱 • (Oryzaephilus surinamensis)，黑葡萄耳喙象(Otiorrhynchus ，小青花金龜（Cbcyceiow/a Jwewwi/a)，辣根猿葉蟲 (Phaedon cochleariae)，金 l + (Phyllophaga spp·、，H 豕金 龜子，小象曱（Pre/w⑽πρ·)，油菜 20 轰跳甲（Psylliodes chrysocephala)，珠1ψ 屬（Ptinus spp·)，20 Eutetranychus spp., Eriophyes spp., Eriophyes spp., Hemitarsonemus spp., genus (//ya/omwa π;?·), hard 蜱Genus (Τχοί/α s/?;?·), black widow, latrodectus mactans, $KMetatetranychus spp., Oligonychus spp., Ornithodoros spp., spider (Panonychus spp·), Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes spp·, Rhipicephalus spp., Rhizoglyphus spp· , Sarcoptes spp., Scorpio maurus, Stenotarsonemus spp., Tarsonemus spp., $cl Tetranychus spp., Vasates lycopersici. A bivalve (Bivalva) organism, for example, a Chilopoda creature, for example, a genus Spp·, a fisherman M (Scutigera spp., a Coleoptera creature, for example, a bean bean o& eciMS), long golden tortoise (yUoreiws sigh /7·), eucalyptus sylvestris (dge/fl such as cfl, golden worm (dgrbies s/τρ·), horse age collection (Amphimallon solstitialis), like 倶Anobium punctatum, Anoplophora πρ·, Anthonomus spp., Anthrenus spp., Apogonia spp., Atomaria spp .), ticket, good idiot {Attagenus spp), ll {Bruchidius obtectus), l I blast [Bruchus spp.), 1 oxygen t{Ceuthorhyhchus spp·,, Cleonus -19- 200814927 mendicus, Conoderus spp·, H nose {Cosmopolites spp·,, ^%H{Cryptorhynchus lapathi), l 亀 亀 {Dermestes spp·, DDiabrotica spp·, Epiiachna spp·, 5 scoop ^XEpilachna spp· , Faustinus cubae, naked or [Gibbium psylloides), Heteronychus arator, Hylamorpha e Legans, North American yak 〇Κ / / 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg leg {Lissorhoptrus oryzophilus), Lz·胤s spp·), Lyctus spp., Meligethes aeneus, Melolontha melolontha, {Migdolus spp), year of the year {Monochamus spp〇5 ® S ^^(Naupactus xanthographus) 9 ψ (Niptus 15 hololeucus), 厍 金 {Oryctes rhinoceros), forged boxes • (Oryzaephilus surinamensis), black grapes Otiorrhynchus, Cbcyceiow/a Jwewwi/a, Phaedon cochleariae, Phylchoga spp., H 豕 龟, 小 (Pre/w(10)πρ·) , Psylliodes chrysocephala, Ptinus spp.

Rhizobius ventralis，家魏蠢{Rhizopertha dominica)，象奏 KSitophilus spp·)，米 l 气（Sphenophorus spp·、，Sternechus spp·，Symphyletes spp·，亲输姦XTenebrio molitor)，後敎基 (Tribolium spp·)，微反蠢慝（Trogoderma spp·)，象1f (Tychius -20- 200814927 spp·)，脊氮天牛屬（Xyhtrechus spp·)，模距步 ψ (Zabrus SPP·、。 彈尾目（Collembola)生物，例如，跳蟲（〇.他而 armatus) ° 5 革翅目（DermaPt⑽)生物，例如，歐洲球蠼 auricularia) 〇 倍足綱目（Diplopoda)生物，例如，具斑馬陸(施 _ guttulatus) ° 雙翅目（Diptera)生物，例如，伊蚊屬以叹户），按 10 蚊屬（Anopheles spp·)，贺特毛玟(Bibio hortulanus)，紅頭 麗蠅（Cfl/ZbAora ，地中海果實蠅（Cer^m·沿 cflpfiflia)，大頭金蠅屬（C7i〇^om>^叹户·），螺旋蠅 (Cochliomyia spp.) ’ 嗜人瘤繩姐（Cor 办/οΜα anthropophaga)，瘅蚊餍（Culex spp.)，疽绳屬（Cuterebra 15 spp.) >油撖欖實蠅（/)此奶〇/⑽e)，膚蠅 • Aown/i/s) ’ 果繩577/7.)，厠繩（Fimw/α 印/?·)，胃 绳屬印；7.)，種繩屬*?/?;?·)，潛繩屬 (Hyppobosca spp·)，皮绳饜（Hypoderma spp·)，潛織屬 (Liriomyza spp.)，綠绳(Lucilia spp·)，家蝶屬（Musca spp·)， 20 Nezara spp·，鼻繩屬57?;?·)，瑞典麥桿繩（C^c/«e//a /h7) ’甜菜潛葉花繩Aj；c^cj；izmz·)，春麥(種麥)蠅 屬{Phorbia spp.)，I鐵凰{Stomoxys spp.)，年故凰{Tabanus spp)，Tannia spp·，歡满九故(Tipula paludosa)，污鐵凰 [Wohlfahrtia spp.)。 -21 - 200814927 腹足綱（Gastropoda)生物，例如，亞利安屬⑽ 叹/?·)，扁峰(万spp·)，水泡螺(方spp·)，蛄 输(Derocenxs spp·)，土媧屬（Ga/心 spp·)，椎實螺(Aymnfleiz spp·)，釘螺（C)«come/(3nfa spp·)，spp·) 〇 5 蠕蟲類（Helminths)生物，例如，十二指腸鉤蟲 {Ancylostoma duodenale)，錫蘭釣蟲 cey/izw/cwm)，巴西鉤蟲（jc少/oWowfl braziliensis)，鉤蟲屬 鲁 （Ancylostoma spp·)，細義（Ascaris lubricoides)，象義屬 *?/?;?·)，馬來絲蟲（Brwg/a mfl/吵/)，迪默利絲蟲 10 (Brugia timorf)，Bunostomum spp·，象^XChabertia spp·、， 支睪屬（Clonorchis spp·)，革換毛樣象義餍（Cooperia 印户·），槍狀肝吸蟲屬（Z)/crc?C(9e//wm吵ρ·)，絲狀肺蟲 (Dictyocaulus filaria)，％ 鑫sXDiphyllobothrium latum)，龍 秦良蟲(Dracunculus medinensis)，絛轰{Echinococcus 15 granulosus)，多烏性包蟲XEchinococcus multilocularis)，境 , 義（JEnterobius vermicularis)，Faciola spp·，扭1 轉義屬 πρ·)，盲腸蟲（Zie/erflKs π;?·)，短小包膜絛 美（Hymenolepis nana)，Hyostrongulus spp·，羅 Μ 叙絲、备 (16^1^0)，十二指腸内的線蟲屬（^所扣〇(^>似^/?；7.)，腸結 20 節象&餍（Oesophagostomum spp.) ’ 泰國肝吸蟲 (Opisthorchis spp·)，綠尾絡、蟲XOnchocerca volvulus)，牛屬 綠、氣M (Ostertagia spp)，生殖器吸备(Paragonimus spp), Schistosomen spp，Strongyloides fuellebomi，糞 4、桿、線盘 [Strongyloides stercoralis)，Stronyloides spp.，無夠條美 -22- 200814927 5Rhizobius ventralis, family Rhizopertha dominica, KSitophilus spp·), Sphenophorus spp·, Sternechus spp·, Symphyletes spp·, XTenebrio molitor, Tribolium spp· , Trogoderma spp., like 1f (Tychius -20- 200814927 spp·), Xyhtrechus spp., Modulus step (Zabrus SPP·, Collembola) For example, hoppers (〇. he and armatus) ° 5 genus (DermaPt (10)) organisms, for example, the European 蠼auricularia) D 〇 纲 ( (Diplopoda) organisms, for example, with zebra land (Shi gu guttulatus) ° double Diptera (for example, Aedes sinensis), by 10 Anopheles spp., Bibio hortulanus, Red-headed flies (Cfl/ZbAora, Mediterranean fruit fly (Cer^) m. along cflpfiflia), genus Gypsophila (C7i〇^om>^ sir), Spiral Flies (Cochliomyia spp.) 'Corporate Tumor Sister (Cor Office / οΜα anthropophaga), 瘅 瘅 (Culex spp. ), genus (Cuterebra 15 spp.) > /) This milk thistle / (10) e), skin fly • Aown / i / s) 'fruit rope 577 / 7.., toilet rope (Fimw / α printed /? ·), stomach rope is printed; 7.), the rope属 *?/?;?·), genus Hyppobosca spp., Hypoderma spp., Liriomyza spp., Lucilia spp., Musca Spp·), 20 Nezara spp·, Nasal genus 57?;?·), Swedish straw rope (C^c/«e//a/h7) 'Beet leafy flower rope Aj; c^cj; izmz· ), spring wheat (Phomabia spp.), I Trangoxys spp., Tabanus spp, Tannia spp, Tipula paludosa, Wohlfahrtia Spp.). -21 - 200814927 Gastropoda creatures, for example, Aryan (10) sigh /?·), flat peak (10,000 spp·), blister snail (square spp), ero (Derocenxs spp·), bandit Genus (Ga/heart spp·), snail (Aymnfleiz spp.), snail (C) «come/(3nfa spp.), spp·) 〇5 Helminths, for example, duodenal hookworm {Ancylostoma Duodenale), Ceylon worm (cey/izw/cwm), Brazilian hookworm (jc less/oWowfl braziliensis), hookworm (Ancylostoma spp.), fine sense (Ascaris lubricoides), elephant genus *?/?;? ), Malay Filaria (Brwg/a mfl/noisy), Brugia timorf, Bunostomum spp·, ^XChabertia spp·, Clonorchis spp·, leather-replacement Elephant 餍 (Cooperia), Gun genus (Z)/crc?C (9e//wm ρ·), filamentous worm (Dictyocaulus filaria),% Xin sXDiphyllobothrium latum), Long Qin Dracunculus medinensis, Echinococcus 15 granulosus, XEchinococcus multilocularis, JEnterobius vermicularis, Faciola spp·, Twist 1 transfer is πρ·), crypt (Zie/erflKs π;?·), short capsule (Hymenolepis nana), Hyostrongulus spp·, Luo Μ 丝, 备(16^1^0), duodenum Nematode within the genus (^>like ^/?;7.), 20 knots & (Oesophagostomum spp.) 'Opisthorchis spp.', green tail, XOnchocerca volvulus), Ostertagia spp, Paragonimus spp, Schistosomen spp, Strongyloides fuellebomi, Dung 4, rod, thread (Strongyloides stercoralis), Stronyloides spp., not enough beauty -22- 200814927 5

10 1510 15

20 (Taenia saginata)，有钩絛螽（Taenia soHum)，緒旋毛螽 (Trichinella spiralis)，旋毛备[Trichinella nativa)，旋毛氣 (Trichinella britovi)，旋毛蟲^Trichinella nelsoni)，旋毛氣 {Trichinella pseudopsiralis) ， Trichostrongulus spp.， Trichuris trichuria，班氏轉、氣(Wuchereria bancrofti)。 也有可能用於控制原生動物類，例如，球蟲(Eimeria)。 異翅目（Heteroptera)生物，例如，菜瓜蟲（乂⑽似 tristis)，Antestiopsis spp·，長涛（Blissus spp·)，i 锋 (Calocoris spp.)，梅噶锋（Campylomma livida)，Cavelerius spp.，臭美(Cimex spp·)，H 毛董育锋(Creontiades dilutus)， 胡椒緣蝽 吵《ws piperis) ， Dichelops furcatus ，20 (Taenia saginata), Taenia soHum, Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis , Trichostrongulus spp., Trichuris trichuria, Wuchereria bancrofti. It is also possible to control protozoa, for example, Eimeria. Heteroptera organisms, for example, Phytophthora (乂(10) like tristis), Antestiopsis spp·, Blissus spp., Calocoris spp., Campylomma livida, Cavelierus spp. , Cimex spp·, H Mao Dongfeng (Creontiades dilutus), pepper 蝽 《 "ws piperis", Dichelops furcatus,

Diconocoris 厶ewe#/，棉紅蝽spp·、、褐蝽 (Euschistus spp·)，竭 M 锋屬（Eurygaster spp·)，Heliopeltis spp·，Horcias nobilellus，峰象疼{Leptocorisa spp.)，葉足 緣锋(Leptoglossus phyllopus)，故萆芎涛屬（Lygus spp.)， 嚴黑長蝽(从(3(：^9/?以以(：仰加似），盲蝽科(^/^>/(^狀），稻綠蝽 (Nezara spp·)，稻雇涛(Oebalus spp·)，Pentomidae，甜菜 擬網蝽(朽^^(2^^(3办(3/(3)，紋埯(尸/以0^/(9厂似*5/7；7.)，棉偽斑 腿盲蝽 〇P如//ws ser/aiws)，persea，錐鼻蟲 (Rhodnius spp)，3 可場育{Sahlbergella singularis、，稻黑、 锋（Scotinophora spp)，網锋（Stephanitis nashf)，Tibraca spp·，吸:L·後锋慝（Triatoma spp·) 同翅目（Homoptera)生物，例如，綠羽蟲屬 (Acyrthosipon spp·)，Aeneolamia spp.，Agonoscena spp·， -23- 200814927 粉益，蔬粉蟲«治），綿 ^{Aleurothrixus spp.) 9 Amrasca spp. > Anuraphis cardui ^ 紅圓虫介〇4⑽577/7·)，梨瘤財(々?/z⑽ow/gmapzW)，蘋果 场（Aphis spp·)，Arboridia apicalis，Aspidiella spp·，儀价 5 (Aspidiotus spp·)，Atanus spp·，馬龄薯長镶场（Aulacorthum solani) ^ ^ ^ (Bemisia spp.) > ^ A ^ (Brachycaudus /ze//c/z^)^z·/)，微管虫牙sp;?·)，菜[吹粉]財 p iBrevicoryne ，小稻褐飛蟲（CW/z’gypowiz marginata)，夜缉（Carneocephala fulgida)，致綿场 ίο (CeraMvizcwwfl /a?n’gem)，珠蟬科(Cercopidae)，龜蝶虫介屬 {Ceroplastes spp.)，萆莓毛管財（Chaetosiphon /rflgfle/i>//z·)，嚴黃雪盾蝓fega/ewsb)，葉蟬 (Chlorita onukii)，胡桃黑、斑场（Chromaphis juglandicola)， 茶褐圓蛉（CTzrysom/^a^s/icMS)，葉蟬w〜7(2)， 15 Coccomytilus halli，Coccus spp·，龜獾額财（Cryptomyzus • ribis、，Dalbulus spp.，^ ^ (Dialeurodes spp·、，木兹 (Diaphorina spp.)，白吩（Diaspis spp·)，縛吩（Drosicha s;?;?·)，圓尾虫牙CDysap/n’s ，粉虫介（D^Asmz.caccws ， 微葉蟬叹/?.)，蘋果(綿）虫牙叹/?·)，斑葉 20 蟬[Erythroneura spp.)，葉缚（Euscelis bilobatus)，板吩 (Geococcws cojffeae) ’ 琉璃葉蟬(//oma/oi/isca coagw/aia) ’ 桃大尾财(办《/〇；?仏隱s arw/zi/z·«以），綿纷(/cerjfl ，葉蟬 (Idiocerus spp.) ，Idioscopus spp.，反觀级{Laodelphax striatellus) y (Lecanium spp.)，爆汾（Lepidosaphes -24- 200814927Diconocoris 厶ewe#/, cotton red 蝽spp·,, brown eucalyptus (Euschistus spp.), genus Eurygaster spp., Heliopeltis spp·, Horcias nobilellus, peak pain {Leptocorisa spp.), leaf foot Leptolossus phyllopus, Lygus spp., sturdy black scorpion (from (3 (:^9/? to (: 仰加), 蝽) (^/^>/ (^ shape), Nezara spp., Oebalus spp., Pentomidae, beet 拟 network (朽^^(2^^(3 (3/(3), 埯( Corpse / with 0 ^ / (9 factory like * 5 / 7; 7.), cotton pseudo-spotted legs blind 蝽〇 P such as / / ws ser / aiws), persea, cone worm (Rhodnius spp), 3 can be bred {Sahlbergella singularis, Scotinophora spp, Stephanitis nashf, Tibraca spp·, Suction: Triatoma spp. Homoptera, for example, green feather Genus (Acyrthosipon spp.), Aeneolamia spp., Agonoscena spp·, -23- 200814927 powdery, vegetable mealworm «treatment", cotton ^{Aleurothrixus spp.) 9 Amrasca spp. > Anuraphis cardui ^ 4(10)577/7·), pear tumor wealth (々?/z(10)ow/gmapzW), Fruit field (Aphis spp.), Arboridia apicalis, Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacorthum solani ^ ^ ^ (Bemisia spp.) > ^ A ^ (Brachycaudus /ze//c/z^)^z·/), microtubular worm sp;?·), vegetable [blowing powder] p iBrevicoryne, small rice brown fly (CW/z'gypowiz marginata), Carneocephala fulgida, to CumMvizcwwfl /a?n'gem, Cercopidae, Ceroplastes spp., Chaetosiphon /rflgfle/i> //z·), Yan Huang Xuedun fega/ewsb), Chlorita onukii, Walnut black, Chromaphis juglandicola, Tea brown 蛉 (CTzrysom/^a^s/icMS), 叶蝉w~ 7(2), 15 Coccomytilus halli, Coccus spp·, Cryptomyzus • ribis, Dalbulus spp., ^ ^ (Dialeurodes spp., Diaphorina spp., Diaspis spp.) , Drosicha s;?;?,), CDysap/n's, powderworm (D^Asmz.caccws, micro-leaf sigh/?.), apple (mian) insect sigh/?·), spot Leaf 20 蝉[Er Ythroneura spp.), Eucelelis bilobatus, Geococcws cojffeae ' 琉 蝉 蝉 (//oma/oi/isca coagw/aia) '桃大尾财(办《/〇;?仏隐 s arw /zi/z·«以), ( cerjfl , Idiocerus spp., Idioscopus spp., inverse level {Laodelphax striatellus) y (Lecanium spp.), blast (Lepidosaphes -24- 200814927

10 1510 15

20 明!?.），芥菜脂虫牙，麥長管虫牙 spp·)，Mahanarva fimbriolata，高聲黎碼{Melanaphis sacchari)，Metcalfiella spp·，I 薇各场{Metopolophium dirhodum)，黑、緣平楚斑辑（Monellia costcdis)，Monelliopsis pecafnj，瘤額財屬（Myzws印/?·)，萵苣財（論⑽《ον/α ，黑尾葉蟬s/?;?.)，稻褐飛兹 {Nilaparvata lugens) 5 Oncometopia spp.，激喻（Orthezia ，揚梅粉蟲（ParMemzWa myrfci/e)，木蟲 (Parair/ozfl s/?/?.)，星盾虫介（Par/izior/a π;?·)，癭綿虫牙 (PempAfgMs 叹/?·) ’ 菲島玉米躐蟬(Peregn’WMs mafi/zj)，粉紛 (Phenacoccus spp.) 5 Phloeomyzus passerinii ^ 虫牙 (Phorodon humuli)，根瘤场（Phylloxera spp.)，拷長盾喻 (Pinnaspis aspidistrae)，粉吩(Planococcus spp.)，梨形原 綿价(Protopulvinaria pyriformis)，桑介殼蟲 {Pseudaulacaspis pentagona)，驗喻（Pseudococcus spp.、， t备（Psylla spp·)，Pteromalus spp·，觀致（Pyrilla spp.)， Wi *(Quadraspidiotus spp.)，Quesada gigas，Rastrococcus spp·，粟緣管场（Rhopalosiphum spp.)”?k 復黑反喻(Saissetia spp.) ， Scaphoides titanus ，麥二岔虫牙(Schizaphis ，西印度細圓盾虫介（iSe/ewflwzWws ariz.cw/aiws)，稻 兹 OSogflia 叹/?·)，白背飛蟲 /wrcz/era)，飛蟲 (Sogatodes spp.) 5 ^ ^{Stictocephala festina) 5 Tenalaphara ，美核桃黑虫牙（77«0Ciz///*s ，沫蟬 spp·)，二岔虫牙（Tbxoj^era *?/?;?·)，溫室粉蟲 -25- 200814927 (Trialeurodes vaporariorum)，豕级（Trioza spp.)，，}、葉缉 spp·)，盾输叹;?.），葡萄根瘤虫牙（巧仏似 vitifolii) ° 520 明!?.), mustard, worm, worm, spp·), Mahanarva fimbriolata, Melanaphis sacchari, Metcalfiella spp·, I (Metopolophium dirhodum), black, marginal spot Monellia costcdis, Monelliopsis pecafnj, genus (Myzws printed /?), lettuce money (on (10) "ον/α, black-tailed 蝉s/?;?.), rice brown feizi {Nilaparvata lugens 5 Oncometopia spp., Metaphor (Orthezia, ParMemzWa myrfci/e, Woodworm (Parair/ozfl s/?/?.), Star Shield (Par/izior/a π;?· ), 瘿 虫 ( (PempAfgMs sigh /?·) 'Peregn'WMs mafi/zj, Phenacoccus spp. 5 Phloeomyzus passerinii ^ Phorodon humuli, Phylloxera spp. ), Pinnaspis aspidistrae, Planococcus spp., Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcus spp., Psylla spp. ), Pteromalus spp., Pyrilla spp., Wi * (Quadraspidiotus spp.), Quesada gigas , Rastrococcus spp., Rhopalosiphum spp.?k, Saissetia spp., Scaphoides titanus, Schimaphis, West Indian sylvestris (iSe/ewflwzWws ariz. Cw/aiws), Inaz OSogflia sigh /?·), Whitebacked worm/wrcz/era), Flying worm (Sogatodes spp.) 5 ^ ^{Stictocephala festina) 5 Tenalaphara, American walnut black fangs (77«0Ciz/ //*s, 蝉 spp·), 岔 岔 ( (Tbxoj^era *?/?;?·), greenhouse mealworm-25- 200814927 (Trialeurodes vaporariorum), 豕 grade (Trioza spp.),,},叶缉spp·), shield sighs;?.), grape root nodule teeth (smart like vitifoli) ° 5

10 1510 15

20 膜翅目（Hymenoptera)生物，例如，鑛角葉蜂屬（Ζ)ζ·;?η·⑽ SPP.)，實葉蜂屬（Hopiocampa spp·)，壤屬（Lasius spp·)，癒 ♦ (Monomorium pharaonis)，大胡蜂屬（Vespa spp·) 〇 等足目（Isopoda)生物，例如，氣婦 vw/gare)，球鼠婦（6>«仏cms 似6//奶），黑潮蟲 scaber) 〇 等翅目（Isoptera)生物，例如，網白蟻類烈 spp.) ^ 白蟻（Odontotermes *?/?/?·) 〇 鱗翅目（Lepidoptera)生物，例如，白毛蟲(Jcrom’cM ma/or)，電紋夜蛾(dei/z.fl /ewcowe/iZ5)，夜蛾印/?·)， 棉葉波紋夜蛾argi//aeea)，大豆夜蛾 5即·），甘藍夜蛾，棉葉穿孔潛蛾 (Bucculatrix thurberiella)，松 K獲（Bupalus piniarius)，德 葉蛾(Cacoeck ，捲葉蛾(G3/7Wiz reifcw/β/ΐβ)，顏果 蠢味ICarpocapsa pomonella)，Cheimatobia brumata，檢螺 ((7/»7(>印/7.)，雲杉捲葉蛾（(^0厂加6^仙广(2/^/而/67^«(3)，葡萄 果蠹蛾（C7j^fl ，縱捲葉蛾屬（C/iflpAiz/ocemy 57?;?·)，棉斑實蛾（五π/似 insulana)，微镇（Ephestia ，棕尾毒蛾(五w/?n9ciz\s ，切根蟲 5^/7.)，褐葉蛾屬（Fe/如 s/7；?·)，大堪模（Giz//enh mellonella) ’ Helicoverpa spp.，梅资备屬（Heliothis spp·、， -26- 200814927 褐戴夜蛾（Hofmannophila pseudospretella)，德葉蛾 (Homona magnanima) ， Hyponomeuta padella ，夜蛾 (Laphygma spp·)，細蛾XLithocolletis blancardella)，綠朱氣 織(Lithophane antennata)，Loxagrotis albicosta ,舞[秦]織 5 *?/?/?·)，天幕毛蟲(Ma/izcosoma «ewsirz’fl)，甘藍 夜蛾(MameWriz ，稻毛腔夜蛾(Moezi ，20 Hymenoptera organisms, for example, Eucalyptus (Ζ) ζ·;?η·(10) SPP.), Hopiocampa spp., Lasius spp·, ♦ (Monomorium pharaonis), Vespa spp. Isopoda creature, for example, vw/gare, ball rat (6>«仏cms like 6//milk), black worm Scaber) Isoptera, for example, the termite genus spp.) ^ Termite (Odontotermes *?/?/?·) Lepidoptera, for example, white caterpillar (Jcrom'cM ma/ Or), Electric Moth (dei/z.fl /ewcowe/iZ5), Night Moth Print /?·), Cotton Leaf Spodoptera argi//aeea), Soybean Spodoptera 5 (), Cabbageworm, Cotton leaf perforated moth (Bucculatrix thurberiella), Bulkus piniarius, Caoeck, G3/7Wiz reifcw/β/ΐβ, Icarocapsa pomonella, Cheimatobia brumata, snail (7/»7(>印/7.), spruce leaf moth ((^0 plant plus 6^xianguang (2/^/ and /67^«(3), grape fruit moth (C7j^fl, Liriodendron (C/iflpAiz/ocemy 57?;?·), cotton spotted moth Five π/like insulana), micro town (Ephestia, brown tail moth (five w/?n9ciz\s, cut rootworm 5^/7.), brown leaf moth (Fe/such as s/7;?·), Giz//enh mellonella ' Helicoverpa spp., Heliothis spp·, -26- 200814927, Hofmannophila pseudospretella, Homona magnanima, Hyponomeuta padella, night Moth (Laphygma spp.), XLithocolletis blancardella), Lithhophane antennata, Loxagrotis albicosta, dance [Qin] weaving 5 *?/?/?·), Canopy caterpillar (Ma/izcosoma «ewsirz'fl ), Cabbageworm (MameWriz, M. meridae)

Mythimna separata，夜蛾（Oria spp·)，稻負泥 A(Oulema _ or少zee)，松夜蛾 CPfl/io/zi /Zammefl)，（棉）紅模玲蟲 {Pectinophora gossypiella)，桔細潛蛾（尸/^//oc«以沿 10 citrelld)，菜粉蝶屬 spp·、，小菜蛾 〇P/wie//a xylostella)，夜蛾(Prodenia spp·)，絲義(Pseudaletia spp·)， 大豆夜蛾 /此/wde似），野模（jPjKrizwWfl nubilalis)，[點备）夜織（Spodoptera spp)，Thermesia gemmatalis，網衣蛾（Tinea pellionella)，袋农蛾（Tineola 15 bisselliella)，穩葉蛾(Tortrix viridana)，夜蛾(Trichoplusia _ 響·）。 直翅目（Orthoptera)生物，例如，家蛾、蟀 dome妨’cms)，東方蜚蠊（Β/βίίβ oWe«ia//s)，德國小蠊 (5/αίίβ//α germawica)，螻蛄（G^y//(9i(3/pa 印/?·)，馬得拉蜚蠊 20 (Leucophaea maderae)，飛虫皇spp.)，蚱猛 (Melanoplus spp.)，美洲大蠕：(Periplaneta Americana)，荒 地虫乍猛OSc/n•对ocercfl gregar/a) 〇 蚤目（微翅目）（Siphonaptera)生物，例如，禽蚤屬 (Ceratophyllus spp·、，東方 tKXenopsylla cheopis)。 -27- 200814927 結閥綱目（Symphyla)生物，例如，庭園么蚰 {Scutigerella immaculata) 〇 總翅目（Thysanoptera)生物，例如，稻薊馬（如/⑹ biformis)，Enneothrips flavens，t 蓿箾馬（Frankliniella 5 例?·），薊馬（Heliothrips 577;?·)，溫室條薊馬扣 femoralis) ·’ Kakothrips spp· ’ 氣镇]錢馬 ^Rhipiphorothrips cruentatus)，胬馬{ScirtothHps spp.)，觀馬(jaeni〇thrips 售 cardamoni)，蘇馬{Thrips spp·、Ό 缨尾目（Thysanura)生物，例如，西洋衣魚 10 saccharina) 0 植物寄生性線轰類包括，例如，粒線蟲屬 MP.) ’ 葉芽線蟲屬（Aphelenchoides 叹/?·)， spp·，私材象鑫XBursaphelenchus spp·)，i 象蟲XDUylenchus dipsaci) ’ 衰金象备慝{Globodera spp)，Heliocotylenchus 15 spp· ’ tL t 象各（Heterodera spp.)，势氣氣{JLongidorus p s/?;?·)，根瘤線蟲屬57?;?·)，根腐線蟲屬 {Pratylenchus spp·)，摄穴氣氣〔Radopholus similes)，螺、旋 線義屬（Rotylenchus spp·)，殘根線美屬（Trichodorus spp·)， 後化據&(Tylenchorhynchus spp·)，款形象蟲XTylenchulus 20 叹Ρ·)，柑插線蟲;（办/e/ic/zw/⑽，劍線蟲屬 {Xiphinema spp.) 0 適當的，根據本發明的活性北合物組合物在某些濃度 或施用率下，也可作為殺草劑、安全劑、生長調節劑或用 於改善植物性質的藥劑、或作為殺微生物劑{例如作為殺 200814927 真菌劑、抗徽劑、殺菌劑、殺病毒劑[包括作為對抗類病 毒(viroid)劑]、或作為對抗ML〇(類-黴漿菌的微生物）及 RLO(類-立克次氏體之微生物）劑}被使用，·適當的，它們 也了作為中間物或如驅物’被應用供合成其他的活性化合 物。 根據本發明，可用於處理全株的植物及植物部位，可 理解的，所稱之植物係指全部的植物與植物族群，例如， 想要的與不想要的野生植物或作物植物（包括天然出現的 作，植物）；作物植物為可被禮植、得自藉由傳統的育種 及最適化方法或藉由生物科技的與基因工程法，或併用這 些方法取彳于者，包括轉殖基因的植物與包括可受植物育 者的權盈保護的與不被保護的植物品種；植物部分可了解 的係指植物在地表上的與在地下部分的全部植物與哭 官，例如，幼芽，葉，花與根，可提及的實例為葉子 15 20 葉、莖桿、樹桿、花、果實體、果子，種子，根，球莖與 匍匐莖；植物的部分也包括被收穫的材料及生長中部 繁殖用材料，例如，種苗、球莖、匍匐莖、插枝及種及 根據本發明以活性化合物組合物處理植物與植物邱 分，係以傳統的方式直接地處理植物本身或作用其 u 環境、生活空間或儲存處，例如藉由浸潰、喷灑、二羞 霧化、撒佈、塗上、注射，以及，對u "、、政 可％I殖材料，特別3 種子，尚可藉由施用一或多層塗覆物之方式處理。引疋 根據本發明的活性化合物組合物_ =於 種子，在此，根據本發日職認為係較麵或制佳的= -29- 200814927 5Mythimna separata, Oria spp., Oulema _ or less zee, CPfl/io/zi/Zammefl, (Pectinophora gossypiella), orange fine Moth (corpse /^//oc« along 10 citrelld), Cabbage spp., Plutella xylostella P/wie//a xylostella), Prodenia spp., Pseudaletia spp. Soybean larvae / this / wde like), wild model (jPjKrizwWfl nubilalis), [point preparation] night weaving (Spodoptera spp), Thermesia gemmatalis, nettle moth (Tinea pellionella), baggy moth (Tineola 15 bisselliella), steady leaf Moth (Tortrix viridana), Noctuidae (Trichoplusia _ ring). Orthoptera organisms, for example, house moths, 蟀dome ' 'cms), oriental 蜚蠊 (Β/βίίβ oWe«ia//s), German cockroaches (5/αίίβ//α germawica), 蝼蛄 ( G^y//(9i(3/pa India/?·), Leucophaea maderae, Flying Emperor spp.), Melanoplus spp., American creep: (Periplaneta Americana ), the wasteland worms OSc/n• ocercfl gregar/a) The genus (Siphonaptera) organisms, for example, the genus Ceratophyllus spp., Oriental tKXenopsylla cheopis. -27- 200814927 Symphya organism, for example, Scutigerella immaculata, Thysanoptera, for example, rice locust (such as /(6) biformis), Enneothrips flavens, t 蓿箾马Frankliniella 5 cases?·), Hummer (Heliothrips 577;?·), Greenhouse horses buckle femoralis) ·' Kakothrips spp· '气镇】钱马^Rhipiphorothrips cruentatus), Hummer {ScirtothHps spp.), Guan Ma (jaeni〇thrips sold cardamoni), Suma {Thrips spp·, Th 缨 ura (Thysanura) organism, for example, 10 saccharina) 0 Plant parasitic line bombs include, for example, the genus Trichomonas MP.) ' Leaf buds Nematodes (Aphelenchoides sigh/?·), spp·, sinensis XBosaphelenchus spp·), i worm XDUylenchus dipsaci) 'Globodera spp', Heliocotylenchus 15 spp· 'tL t each (Heterodera spp. ), qi qi {JLongidorus ps/?;?·), Rhizoctonia genus 57?;?), root rot nematode {Pratylenchus spp.), snail gas (Radopholus similes), snail, snail (Rotylenchus spp·), Root line (Trichodorus spp.), post-chemical according to & (Tylenchorhynchus spp.), the image of the insect XTylenchulus 20 sigh ·), citrus elegans; (do / e / ic / zw / (10), the sword genus { Xiphinema spp.) 0 suitably, the active bead composition according to the invention may also act as a herbicide, safener, growth regulator or agent for improving the properties of plants, or at certain concentrations or application rates, or As a microbicide {for example, as a fungal agent, an anti-infective agent, a bactericide, a viricide [including as a viroid agent], or as an anti-ML 〇 (mycoplasma-like microorganism) and RLO (Microorganisms of the genus rickettsia) are used, and, where appropriate, they are also used as intermediates or as a precursor to be used for the synthesis of other active compounds. According to the present invention, it can be used to treat plants and plant parts of a whole plant. It is understood that the term "plant" refers to all plants and plant groups, for example, desired and unwanted wild plants or crop plants (including natural occurrences). Crops, plants, plants that can be bred, from traditional breeding and optimization methods, or through biotechnology and genetic engineering, or combined with these methods, including transgenic genes Plants and unprotected plant species including those that are subject to the rights of planters; plant parts are understood to refer to plants on the surface and all plants in the underground part with crying officials, for example, young shoots, leaves , flowers and roots, examples which may be mentioned are leaves 15 20 leaves, stems, tree stems, flowers, fruit bodies, fruits, seeds, roots, bulbs and stolons; parts of plants also include harvested materials and growth in the middle The treatment of plants and plant parts with active compounds according to the invention, for example, seedlings, bulbs, stolons, cuttings and seeds, is treated directly in a conventional manner The plant itself acts on its u environment, living space or storage, for example by dipping, spraying, dizzying, spreading, spreading, injecting, and, for u ", 政可% Special 3 seeds can still be treated by applying one or more layers of coating.活性 活性 活性 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋 疋

10 1510 15

20 =物，係較佳者’於是，由有害生物造叙作物植物之 才貝告，可旎儘早出現於種子儲存期間及種子被引入土疒 中、及植物萌發後之極短時間内即受到攻擊，此期間= 地為關鍵點，係由於生長中的植物的根及幼苗特^地敏 感，且甚至是微量的傷害即會導致整株植物之死亡，藉由 使用適當的組成物以保護種子及萌發中的植物因此^ 地令人感到興趣。 、 藉由處理植物的種子以防治有害生物之方法已被知 道好長-段時間且為不斷的被改進之目標，然而，種子的 處理常遭遇到-連串無法被令人滿意地解決的問題，於 是，有必要發展供保護種子及萌發中的植物之方法，使得 不需在播種後或植物萌發後立即再施用作物保護劑，此外 也有必要最適化所應用的活性化合物的量，以提供對種子 及萌芽中的植物之最適當的保護，免於受到有害生物之攻 擊，但又不會讓所用的活性化合物傷害到植物本身；特別 的，供處理種子的方法也應將轉殖基因植物的内部的殺昆 蛛的性質列入考慮，使種子與萌芽中植物可以使用最低量 的作物保護劑以達到最適當的保護作用。 因此，本發明也相關於，特別是一種保護種子及萌發 中的植物以對抗有害生物的攻擊之方法，係包含以根據本 發明的活性化合物組合物處理種子；根據本發明用於保護 種子及萌發中的植物以對抗有害生物的攻擊之方法包括 一種方法，其中種子係同時經一種式Z的活性化合物及一 種1至24類的擬除蟲菊酯類處理過；本發明也包含一種 -30- 200814927 10 15 20 方法’其巾_子係在得的相U式I的活性化 合物及-種1 i 24類的擬除絲g旨類處理；本發明 於以根據本發明的活性化合物組合物用於處理種子以便 保護種子及由其萌發的植物對抗有害生物之魏；再者， 本發明關独根據本發明的活性化合物組合物處理過以 便受到保護免於有害生物人叙種子；本發明也關於同時 ^ ♦種式（1)的活性化合物及—種1至24類的擬除轰菊醋 類處理的種子；本發明也關於在不同時間點下以—種 ^活f化合物及—種1 i 24類的擬除蟲菊賴處理的種 不同時間點下以—種式⑴的活性化合物及一種1至 層4勺人一、物可存在於種子的不同層次上，在此， 化合物及可選擇地分開地存在於中間 於一插絲2 # 至24類的擬除蟲菊醋類；本發明也關 2續的擬除蟲'H—，1)的活性化合物以及—種1至 —層❹財覆物的組分方式，或作為另 本發明的優點夕 A t 特別的全身性所 為’根據本發明的化合物組合物之 保護種子本身生貝，係指以這些組成物處理種子，不僅能 生物之攻擊，γ也使得萌芽後的植物得到保護，免於有害 短時間A χ此種方式，可省去在作物播種時以及之後 1内U即進行的處理。 77 一優點為 性，根據本發明的、、^於個別的活性化合物之㈣蟲的活 居性化合物組合物之協乘地增加的殺昆 -31 - 200814927 520 = object, better - 'Therefore, the pests of the crops are planted by the pests, which can occur as early as possible during seed storage and when the seeds are introduced into the soil and the plants are germinated in a very short time. Attack, during this period = the ground is the key point, because the roots and seedlings of the growing plants are sensitive, and even a small amount of damage will lead to the death of the whole plant, by using appropriate composition to protect the seeds. And the plants in the germination are therefore of great interest. The method of treating plant seeds to control pests has been known for a long period of time and is a continuous improvement target. However, the treatment of seeds often encounters a series of problems that cannot be satisfactorily solved. Therefore, it is necessary to develop a method for protecting the seed and the germinated plant, so that it is not necessary to apply the crop protection agent immediately after sowing or after the germination of the plant, and it is also necessary to optimize the amount of the active compound applied to provide a The most appropriate protection of the seed and the plant in the bud, from the attack of the pest, but does not let the active compound used harm the plant itself; in particular, the method for treating the seed should also be transferred to the plant The nature of the internal killing spider is taken into consideration so that the seed and the germinated plant can use the minimum amount of crop protection agent to achieve the most appropriate protection. Accordingly, the invention is also related, in particular, to a method of protecting a seed and a germinated plant against attack by a pest, comprising treating the seed with the active compound composition according to the invention; for protecting the seed and germination according to the invention The method of attacking a pest against a plant comprises a method wherein the seed is simultaneously treated with an active compound of formula Z and a pyrethroid of from 1 to 24; the invention also comprises a -30- 200814927 10 15 20 The method 'there is a treatment of the active compound of the formula I and the fibril g of the type 1 i 24; the invention is used for the active compound composition according to the invention The seed is treated to protect the seed and the plant germinated therefrom against the pest; furthermore, the invention is treated according to the active compound composition of the invention so as to be protected from pests; the invention also relates to Simultaneously, the active compound of the formula (1) and the seed of the 1 to 24 class of pyrethroid treated seeds; the present invention also relates to at different time points The active compound of the formula (1) and the compound of the formula (1) and a kind of 1 to 4 scoop of human beings may exist in different seeds at different time points in the treatment of the compound and the species i i 24 . In this context, the compound and optionally the pyrethroid vinegar are present in the middle of a plug 2 # to 24; the invention is also a continuation of the pseudo-insect 'H-, 1) The active compound and the component form of the 1st to the layer of the invention, or as a further advantage of the present invention, the special systemicity of the compound composition according to the present invention, the seed itself is a raw shell, These compositions treat the seeds not only for biological attack, but also for the germinated plants to be protected from harmful short-time A. This way, the treatment that is carried out at the time of crop planting and after 1 crop can be omitted. 77. An advantage of the synergistic increase in the synergistic composition of the active compound composition of the individual active compound according to the present invention - 31 - 200814927 5

10 15 20 蟲之活性，遠超過被預期的兩個別地被施用的活性化合物 之活性和，此外，相較於個別的活性化合物之殺直菌的、、舌 ，，根據本發明的活性化合物組合物之協乘地增加的殺真 菌之活性’也遠超過被軸的兩個別地被顧的活性化人 物之活性和’使其有可能最適化所應用的活性化合物二 同樣的，要被視為優點者係根據本發明的活性化合物 組合物也可被應毅’軸是轉殖基因_子，由此ς子 長出之植物能表現-種蛋白質直接對抗有害生物，藉由 據本發明的活性化合物組合減理這類種子，可藉由 如’僅僅是所表現的殺昆蟲的蛋白f，使有害生物得到防 治，且額外地受到根據本發明的活性化合物組合物之保 以對抗傷害。 ' 根據本發明的活性化合物組合物適於供保護被應用 在農業、溫室、林業或園藝中之任何所述的植物品種_ ^特別是使用在下述植物的種子：玉米，花生，油菜， 二至I粟，大豆，棉花，甜菜（例如糖甜菜及飼料甜菜）， 稻米，高梁及小米，小麥、大麥、燕麥，黑麥，向曰赛， 终草，馬龄薯或蔬菜(例如蕃名、白菜），根據本發明的活 ，化合物組合物同樣也適用於供處理果樹及如上述的蔬 菜之種子’特別重要的是使用在處理玉米、大豆、棉花、 小麥、及油菜或蕓薹的種子。 如上面已提到的，以根據本發明的活性化合物組合物 處理轉殖基因_子方面也特別的重要，f慣上，受處理 -32- 200814927 的植物種子之型式包含至少一種能控制，特別是具有殺蟲 的性質之多肽的表現之異源的基因，本文中，在轉殖基因 的種子内之異源的基因可能衍化自微生物，例如，桿菌 (如"似）、根瘤菌（及他—·圆）、假單胞菌CPsewi/om⑽似）、 5 沙雷氏菌、木黴菌（7WcA〇i/er_)、棒狀桿菌 (C/aWZmcier)、囊狀體内生菌根菌（G/omt«)或膠狀青黴菌 本發明因此特別適於供處理已包含至少一 瞻種來自桿菌屬之異源的基因，且此基因產物顯現有活性對 抗歐洲玉米螟及/或玉米切根蟲之轉殖基因的種子，特別 10 佳地，此異源的基因係來自蘇利桿菌 thuringiensis) ° 本發明的内文中，根據本發明的活性化合物組合物係 單獨的或在適當的配製劑内被施加至種子上，較佳地，種 子係在足以避免在處理期間受到傷害的穩定狀態下被處 15 理；通常，種子可在介於收穫與播種間的任一時間點下被 p 處理，種子通常使用已分離自植物並已除去穗軸、殼、莖 桿、外套（英）、鬚毛或果肉者。 當處理種子時，通常要極為小心地，將施用至種子上 的根據本發明的活性化合物組合物的量及/或另外選用的 20 添加物的量列入考慮’使得植物的萌發不會受到不利的影 響，或導致植物的傷害，特別要牢記在心的是，施用在某 種施用率下可造成植物毒性的活性化合物下。 此活性化合物組合.物可被轉變成習用的配製劑，例 如，溶液、乳液、可濕性粉末、水-及油-基的懸浮液、粉 -.33- 200814927 劑、塵劑、糊劑、可溶性粉末、可溶性粒劑、用於撒播之 粒劑、懸浮-乳液濃縮物、浸潤了活性化合物之天然材料、 浸潤了活性化合物之合成材料、肥料、以及包覆於聚合性 材料内之微膠囊被使用。 這些配製物係以已知的方式產生，例如，將活性化人 物與展延劑混合，展延劑係指液體溶劑類及/或固體截ς 類，選擇地使轉面活性伽，即，乳化細及= 劑類及/或泡沫形成劑；配製劑可在適當的工廠内制：: 是在使用前或使用時配製。 衣爾或 適於作為辅助劑使用者為適於加入至組成物 或其衍生的配製物(例如’喷難、種子敷料）巾柄及/ ::別是科技的性質及/或特別的生物性質，典：的 辅助劑為：展延劑、溶劑類及載劑類。 、田的 15 、適當的展延料，例如’水，極性及非贿 的液ϋ類’例如’芳族及非·芳族的烴類(例如，歸炉*予 $苯烷基萘類’氯苯類)’醇類及多醇 Π 其可經取代，化及/級化），麵（例如，丙酮的每’ 20 =(包括脂肪及油質)及(聚)醚類’無取代的及經::)， 痛’醯胺類，内醯胺類（例如，Ν-燒基料酉同類^代的 酉旨類，石風類及亞石風類(例如，二甲亞石風）。 叫及内 〜如果使用的展延劑為水，也有可能使用’例如 =劑作為辅助溶劑類，主要地，適當的 有機 族類’例如，二甲苯、甲苯或炫基萘類；氯化;;芳 乳化的脂職_，例如，氯苯類、氯乙烯類或二氯2及 -34- 200814927 脂肪族烴類，例如環P岭々 ^ 衣己烷或石蠟類，例如，石油分劃物. 類.11=1%心 例如，丁醇或甘醇及其醚類與酉旨 頰，sig類，例如，丙顯J， 、呢 己’，強極性>谷劑類’例如二甲亞砜；以及水。 適當的固體载劑類為： 例如，銨鹽類與研磨 點土、^ H過的然:礦物類，例如，高嶺土、 站土 ，月石、白堊土、；P；盆 _ ^ + v ^ 央、吴國活性白土、蒙脫土或矽 10 15 20 石夕，，4卜4 Τ’田1 口成礦物類’例如’高度分散的二氧化 例如平㈣酸鹽類；適於製備顆粒體之固態載劑為， ^如’礙碎並分劃過的天然岩石，例如，方解石、大理石、 f石、海泡石及白雲石’及無機與有機碎料之合成的顆 粒’及有機材料的顆粒，例如，、紙、鋸屑、椰子殼、玉米 穗軸與料莖；適當的乳化劑及/或輯形成㈣：例如， 非離子及陰離子乳化_，例如，聚氧⑽脂肪酸醋類， 聚^乙烯脂肪族醇_ ’例如，烧基芳絲甘醇醚類、烧 基％酸鹽類、烷基硫酸鹽類、芳基磺酸鹽類以及蛋白質水 解產物；適當的分散劑為非離子及/或離子物質，例如， 下類之醇·Ρ〇Ε-及/或_ΡΟΡ,類，酸及/或p〇p_p〇E酯類， 烧基芳基及/或POP-POE醚類，脂肪及/或！>0?_1>0£加合 物，POE-及/或POP-多羥基衍生物，p〇E_及/或pop·山梨 醇酐或-糖加合物，烷基或芳基硫酸酯類，烷基_或芳基磺 酸酯類以及烷基或芳基之磷酸鹽類或相關之PO-醚加合 物，此外，適當的寡-或聚合物，例如，那些衍生自乙烯 性單體者，來自丙烯酸者，來自EO及/或PO本身或併用， -35. 200814927 例如，(聚）醇類或（聚） 酸衍生物、無修飾的及έ 也有可能使用木質素及其磺 肪族的磺酸類及其鱼审:修飾的纖維素、芳族的及/或脂 枯著劑類’例如、，羧=合物。 膠態之天然的及合成的^甲基纖維素與呈粉狀、粒狀或乳 烯醇及聚乙稀醋_旨，2物類’例如’***膠、聚乙 氧 與卵雜，以及合成㈣㈣’例如’腦_ 也有可能用及著曰質類’均可使用於調配物中 化鐵，二氧化鈦及普魯么例如，無機色素類，例如 10 15 20 素染料類，偶氮類染料;^M以及有機染料類，例如，茜 士八加L牌 4及至屬駄花青染料，以及微量營養 成分，例如，鐵、錳、硼 m 銅、鈷、鉬及鋅等的鹽類。 "此、、加物為香水、礦物或植物油，選擇地經 修飾的油類、錢及營養素（包括微量營養素），例如，鐵、 錳、硼、銅、鈷、鉬及鋅等的鹽類。 用於改#*化學的及/或物理安定性之安定劑類，例如’ 低溫妓_、_咖、抗氧化物類、絲妓劑類或 其他的試劑，也可存在於調配劑中。 調配劑中通常包含介於〇〇1與98%重量計的活性化 合物，宜為介於0.5與90%間者。 根據本發明的活性化合物組合物可使用其市售玎得 的配製劑型式，或從此調配劑調配成使用型式使用，或與 其他的活性化合物類(例如’殺昆蟲劑，引誘劑，***劑， 殺菌劑，殺瞒劑，殺線蟲劑，殺真菌劑，生長調節物質或 殺草劑)作成混合物被使用；殺昆蟲劑類包括，例如，尤 -36、 200814927 其是：磷酸酯類，胺基曱酸酯類，羧酸酯類，氣化的烴類， 苯基脲類，微生物產生之製劑類，等等° 也可以是與其他已知的活性化合物（例如，殺草劑）， 或與肥料及生長調節劑作成混合物使用。 當作為殺昆蟲劑使用時，根據本發明的活性化合物組 合物也可使用其市售可得的配製劑型式，或從此調配劑調 配成使用型式使用，或與協乘劑成混合物使用，協乘劑係The activity of 10 15 20 insects far exceeds the activity of the two active compounds which are expected to be applied and, in addition, the active compounds according to the invention, compared to the individual active compounds of the fungi, the tongue The synergistically increased fungicidal activity of the composition is also much greater than the activity of the two activated individuals of the axis and the active compound II that makes it possible to optimize the application. It is considered that the active compound composition according to the present invention can also be converted into a gene by the Yingyi 'axis, whereby the plant grown by the scorpion can express the protein directly against the pest, by the present invention The combination of active compounds reduces such seeds, and the pest can be prevented by, for example, 'only the insecticidal protein f being expressed, and additionally protected against damage by the active compound composition according to the invention. The active compound composition according to the invention is suitable for the protection of any of the plant varieties described in agriculture, greenhouse, forestry or horticulture - in particular for the use of seeds of the following plants: corn, peanuts, canola, two to I millet, soybean, cotton, sugar beet (such as sugar beet and fodder beet), rice, sorghum and millet, wheat, barley, oats, rye, sorghum, terminal grass, horse-aged potato or vegetable (eg, name, cabbage) According to the present invention, the composition of the compound is also suitable for the treatment of fruit trees and seeds of vegetables as described above. It is particularly important to use seeds for the treatment of corn, soybean, cotton, wheat, and canola or alfalfa. As already mentioned above, it is also of particular importance to treat the transgenic gene with the active compound composition according to the invention, which is conventionally employed, the type of plant seed treated by -32-200814927 comprises at least one which can be controlled, in particular Is a heterologous gene of the performance of a polypeptide having insecticidal properties. In this context, a heterologous gene in the seed of a transgenic gene may be derived from a microorganism, such as a bacillus (eg, "like), rhizobium (and He--circle, Pseudomonas CPsewi/om (10), 5 Serratia, Trichoderma (7WcA〇i/er_), Corynebacterium (C/aWZmcier), cystic in vivo mycorrhizal fungi ( G/omt«) or Penicillium cloacae The present invention is therefore particularly suitable for the treatment of genes comprising at least one heterologous source from the genus Bacillus, and the gene product exhibits activity against European corn borer and/or corn cutting roots. Seeds of the transgenic gene of the worm, particularly preferably, the heterologous gene line is derived from the genus Suricus thuringiensis) ° In the context of the present invention, the active compound composition according to the invention is used alone or in a suitable formulation Applied to the seed, Preferably, the seed is in a stable state sufficient to avoid damage during processing; typically, the seed can be treated by p at any point between harvesting and sowing, and the seed is usually isolated from the plant. The cob, shell, stem, coat (English), hair or flesh have been removed. When treating seeds, it is usually very important to take into account the amount of the active compound composition according to the invention applied to the seed and/or the amount of the additionally selected 20 additives, so that the germination of the plant is not adversely affected. The effect, or damage to the plant, is to be kept in mind, under application of the active compound which causes phytotoxicity at a certain application rate. The active compound combination can be converted into a conventional formulation, for example, a solution, an emulsion, a wettable powder, a water- and oil-based suspension, a powder-.33-200814927, a dust, a paste, Soluble powders, soluble granules, granules for spreading, suspension-emulsion concentrates, natural materials infiltrated with active compounds, synthetic materials infiltrated with active compounds, fertilizers, and microcapsules coated in polymeric materials are use. These formulations are produced in a known manner, for example, by mixing an active person with a stretching agent, which refers to a liquid solvent and/or a solid paraplegic type, optionally devolatilizing, ie, emulsifying Fine and = agent and / or foam forming agent; the formulation can be made in a suitable factory:: is prepared before use or at the time of use. Zeer or a user suitable as an adjuvant is suitable for addition to a composition or a formulation derived therefrom (eg, 'spray, seed dressing) towel handle and/or other technical properties and/or special biological properties , Code: The adjuvants are: extenders, solvents and carriers. 15 , appropriate extension materials, such as 'water, polar and non-bribery liquids' such as 'aromatic and non-aromatic hydrocarbons (for example, to the furnace * to the phenylalkyl naphthalenes) Chlorobenzenes) 'Alcohols and polyols Π which can be substituted, graded and/or graded), noodles (for example, every '20 of acetone (including fats and oils) and (poly)ethers are unsubstituted And::), pain 'melamines, indoleamines (for example, Ν-burning base 酉 酉 ^ 酉 , , , , , , , , , , , , , , , , , , , , , , , 石 石 石 石 石 石 ( ( (叫和内~ If the propellant used is water, it is also possible to use 'for example, an agent as an auxiliary solvent, mainly a suitable organic group' such as xylene, toluene or cyanophthalene; chlorination; Aromatic emulsified fat _, for example, chlorobenzenes, vinyl chlorides or dichloro 2 and -34- 200814927 aliphatic hydrocarbons, such as cyclopentene oxime or paraffin, for example, petroleum partitions .11=1% heart, for example, butanol or glycol and its ethers and sputum cheeks, sig, for example, C, J, 、, 'strong polarity> granules such as dimethyl Sulfone; and water Suitable solid carriers are: for example, ammonium salts and grinding point soils, and salts: minerals, for example, kaolin, standing soil, moonstone, chalk, P; pot _ ^ + v ^ , Wu Guo active clay, montmorillonite or 矽10 15 20 Shi Xi,, 4 Bu 4 Τ '田1 口 into minerals' such as 'highly dispersed dioxide such as flat (tetra) acid salts; suitable for the preparation of granules Solid carrier is, for example, 'natural rock that is broken and divided, for example, calcite, marble, f stone, sepiolite and dolomite' and synthetic particles of inorganic and organic scraps' and particles of organic materials , for example, paper, sawdust, coconut shell, corn cobs and stems; suitable emulsifiers and/or formations (iv): for example, nonionic and anionic emulsifiers, for example, polyoxygen (10) fatty acid vinegars, polyethylene Aliphatic alcohols - 'for example, alkyl aryl alcohol glycol ethers, alkyl ester salts, alkyl sulfates, aryl sulfonates and protein hydrolysates; suitable dispersants are nonionic and / or Ionic materials, for example, the following alcohols, strontium-and/or ΡΟΡ, classes, acids and/or p〇p_p〇E esters, alkyl aryl and/or POP-POE ethers, fats and/or !>0?_1> 0 £ adducts, POE- and/or POP-polyhydroxy derivatives, P〇E_ and / or pop sorbitol or - sugar adducts, alkyl or aryl sulfates, alkyl or aryl sulfonates and alkyl or aryl phosphates or related PO-ether adducts, in addition, suitable oligo- or polymers, for example those derived from vinyl monomers, from acrylics, from EO and/or PO itself or in combination, -35. 200814927 For example, ( Poly)Alcohols or (poly)acid derivatives, unmodified and oxime It is also possible to use lignin and its sulfonated sulfonic acids and their fish: modified cellulose, aromatic and/or fat-drying agents Class ', for example, carboxy = compound. Colloidal natural and synthetic methylcellulose with powdered, granulated or lactenol and polyethylene vinegar, 2 species such as 'arabin gum, polyethoxylate and egg, and synthetic (4) (4) 'For example, 'brain _ may also be used with enamel class' can be used in the formulation of iron, titanium dioxide and prolu, for example, inorganic pigments, such as 10 15 20 dyes, azo dyes; M and organic dyes, for example, Gentleman's Eight Plus L brand 4 and to phthalocyanine dyes, and trace nutrients, for example, salts of iron, manganese, boron m copper, cobalt, molybdenum and zinc. "This, add-on for perfumes, minerals or vegetable oils, selectively modified oils, money and nutrients (including micronutrients), for example, salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc . Stabilizers used to modify #* chemical and/or physical stability, such as 'low temperature 妓, _ coffee, antioxidants, silk mites or other agents, may also be present in the formulation. The formulation typically comprises between 〇〇1 and 98% by weight of the active compound, preferably between 0.5 and 90%. The active compound compositions according to the invention may be formulated in the form of their commercially available formulations, or formulated from the formulation into a use form, or with other active compounds (eg 'insecticides, attractants, infertile agents' , fungicides, acaricides, nematicides, fungicides, growth regulators or herbicides) are used as a mixture; insecticides include, for example, especially -36, 200814927 which are: phosphates, amines Ruthenium esters, carboxylates, gasified hydrocarbons, phenylureas, microbial-producing preparations, etc. ° may also be combined with other known active compounds (eg, herbicides), or Used in combination with fertilizers and growth regulators. When used as an insecticide, the active compound composition according to the invention may also be used in the form of a commercially available formulation, or may be formulated from the formulation into a use form, or may be used in admixture with a synergist, Agent system

10 1510 15

20 一種可增進活性化合物的作用，但本身不一定有活性之物 質。 由市售可得的製劑調配得的使用型式中的活性化合 物含量可在很大範圍間變化，使用型式中的活性化合物濃 度可為介於0·00000001至95%重量計的活性化合物，宜 為介於0.00001與1%重量計間。 施用的方式以適用於使用型式的方式。 如月〕面已提過的，根據本發明可處理 立 較:的具體實施例中，用伽 或那些藉由傳統生物育種方法取 例如那些絲⑽物' 另-較佳的具體實施例中 因：：：’在 適當的併用傳財法 其^由基H法’且 種(基因改造的有機俨 土因植物與植物栽培品 植物的部位，’或，，植物 ，苴人位，所明的部位，，、” 特別適宜地，义，、3義如前面的解釋。 得或被使用中之植2柄明用於處理之植物為那Α可購 植物栽培絲，植㈣培品财理解= -37- 200814927 才曰藉由傳統月種U由突變或藉由重組丽A技術而取得 具有新穎性質（”特色”)之植物，這些可以是栽培品種 (CUl—S)、同型小種(bi吻Pes)或基因型種(g_types)。 >魏物的品種缝物栽培品種，其分佈與生長條件(土 5 壤，乳候，生長期間，營養狀態），根據本發明的處理也 可導致超加成的（“協乘的”)效果，料，例如，減少的施 用率及/或增廣的活性譜及/或增加可根據本發明被使用的 • ⑯質及組成物的活性，㈣的植物生長，更耐高溫或耐低 /皿’更耐乾干或耐水或耐土壤鹽分含量，增加的開花期， 1〇 更容易的，加速的成熟，更高的收穫量，更佳的品質 及具較尚的營養價值之收穫物，收穫產品的更佳的儲 存安疋性及/或加工性，均可能超出實際被預期的效果。 、根據本發明被處理之較佳的轉殖基因的植物或植物 栽培品種（即那些藉由基因工程的方法取得者）包括所有那 15 些，=基因改造，獲得有利的有用的特色之基因材料之植 鲁 物這通知'色的貫例為·較佳的植物生長、更耐高溫或耐 低/JEL，更耐乾干或水或土壤中鹽含量、增加的開花期、更 容易的收割、加速的成熟、更高收量、收穫品之較佳品質 及/或較高的營養價值、收穫品之較佳的儲存安定性及/或 2〇 加工性，值得特別被強調之這類特色的實例為，植物對抗 動物及微生物等有害生物（例如，昆蟲，蟎類，植物致病 性真菌、細菌及/或病毒類）之具更佳的防禦性，也增加植 物對某些具除草活性化合物之耐性，可提及的轉殖基因的 植物為重要的作物植物，例如穀物（小麥、稻米），玉米， -38- 200814927 大豆，馬鈴I，吨，蕃％、豆子及其他蔬菜品種、棉花， 煙草、油菜以及果樹(蘋果樹，梨樹，柑橘樹與葡萄藤）， 且特別要強调的為玉米，大豆，馬鈴薯，棉花與油菜，尤 其被強调的特色為藉由形成於植物中的毒素使增加植物 5 抵抗力以對抗昆蟲、蟎類、線蟲及媧牛及蛞蝓之能力，特 別是那些藉由來自於蘇力菌桿菌（及^如沿)的 基因材料者（例如，藉由基因CryIA⑻，CryIA(b)， _ CryIA(c)，CryllA，CrylllA，CryIIIB2，Cry9c，Cry2Ab，20 A substance which enhances the action of an active compound but which is not necessarily active per se. The active compound content in the use form formulated from commercially available formulations may vary widely, and the active compound concentration in the use form may range from 0,000,000 to 95% by weight of active compound, preferably Between 0.00001 and 1% by weight. The manner of application is in a manner suitable for the type of use. As has been mentioned in the drawings, in accordance with the present invention, in the specific embodiment, the gamma or those obtained by conventional biological breeding methods such as those of the wire (10) are also preferred. :: 'In the appropriate combination of the use of wealth and its ^ by the base H method' and species (genetically modified organic bauxite plant and plant cultivation plant parts, 'or, plants, 苴 people, the known parts ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 37- 200814927 A plant with novel properties ("features") obtained by mutation or by recombination of Li A technology, which can be cultivar (CUl-S), homotype (bi kiss) Pes) or genotype (g_types). > Weed cultivar cultivar, its distribution and growth conditions (soil, soil, milk, growth period, nutritional status), the treatment according to the invention can also lead to super Addition ("co-multiply") effect, material, for example, reduced Rate and / or augmented activity spectrum and / or increase the activity of the 16 quality and composition that can be used according to the invention, (4) plant growth, more high temperature resistance or low / dish 'more resistant to dry or water resistant or resistant Soil salinity, increased flowering, 1〇 easier, accelerated maturity, higher yield, better quality and higher nutritional value, better storage stability of harvested products And/or processability, which may exceed the actual expected effect. Plants or plant cultivars (ie those obtained by genetic engineering methods) that are better treated according to the invention include all 15 Some, = genetically modified, to obtain beneficial and useful features of the plant material of the plant, this notification 'color of the case for better plant growth, more high temperature or low / JEL, more resistant to dry or water or soil Medium salt content, increased flowering period, easier harvesting, accelerated ripening, higher yield, better quality of the harvest and/or higher nutritional value, better storage stability of the harvest and/or 2〇Processability, value An example of such a feature that is particularly emphasized is that plants are more resistant to pests such as animals and microorganisms (eg, insects, mites, phytopathogenic fungi, bacteria and/or viruses) and also increase Plants for certain herbicide-tolerant compounds, plants that can be mentioned as transgenic genes are important crop plants, such as grain (wheat, rice), corn, -38- 200814927 soybean, horse bell I, tons, fan% , beans and other vegetable varieties, cotton, tobacco, canola and fruit trees (apple, pear, citrus and vine), with particular emphasis on corn, soybeans, potatoes, cotton and canola, especially emphasized It is characterized by the ability to increase plant 5 resistance by toxins formed in plants to combat insects, mites, nematodes and yak and ticks, especially those derived from S. faecalis (and Gene material (for example, by gene CryIA (8), CryIA (b), _ CryIA (c), CryllA, CrylllA, CryIIIB2, Cry9c, Cry2Ab,

Cry3Bb及（^1?以及也包括其組合物）(後面歸之為”所植 10 物”）；其他也特別要強調的特色為，藉由全身性取得抗性 (SAR)、systemin、植物抗毒素（卩]^〇&16\丨118)、誘發劑 (elicitor)及抗性基因及相關的表現的蛋白質及毒素而使植 物對抗真菌、細菌及病毒得到增加的防禦力；也特別要被 強调的特色為’植物對某些具除草地活性化合物（例如， I5 咪唑啉酮類，磺醯基脲類，嘉磷塞(glyphosate)或膦基三辛 I (phosphinotricin)(例如”PAT”基因))之增加的耐性；參與至 所要的特色的基因毫無疑問的也可與他種基因成混合型 式出現於轉殖基因的植物中，可被提及的”Bt植物”之實例 為以下述的貿易名稱(trade name)被販售之玉米品種、棉花 20 品種、大豆品種及馬鈴薯品種：YIELD GARD® (例如玉 米，棉花，大豆），KnockOut® (例如玉米），StarLink® (例 如玉米），Bollgard® (棉花），Nucotn® (棉花）與 NewLeaf® (馬铃署）；可提及的耐-殺早劑的植物類為玉米品種、棉化 品種及大豆品種，其以下列貿易名稱被販售：Roundup -39- 200814927Cry3Bb and (^1? and also its composition) (later referred to as "planted"); other features that are particularly emphasized are: systemic resistance (SAR), systemin, phytoalexin (卩]^〇&16\丨118), elicitor and resistance genes and related proteins and toxins to increase the defense of plants against fungi, bacteria and viruses; The characteristics of the tune are 'plants for certain herbicidal compounds (eg, I5 imidazolinones, sulfonyl ureas, glyphosate or phosphinotricin (eg "PAT") genes. )) increased tolerance; genes involved in the desired characteristics are undoubtedly also present in a mixed form with other genes in plants of the transgenic genes. Examples of "Bt plants" that may be mentioned are as follows Trade name sold by corn variety, cotton 20 variety, soybean variety and potato variety: YIELD GARD® (eg corn, cotton, soybean), KnockOut® (eg corn), StarLink® (eg corn), Bollgard® (cotton ), Nucotn® (cotton) and NewLeaf® (Masing); the plant-to-killer agents that can be mentioned are corn, cotton and soybean varieties, which are sold under the following trade names: Roundup - 39- 200814927

Rea，®㈤嘉磷塞’例如玉米，棉花，大豆），⑽吻[尬⑩ 基—辛’例如油菜)，IMI⑧(耐咪唑啉酮)及聊⑧(耐 石黃酿^ ’例如玉米）；可提及的耐-除草劑之植物（以傳統 f式育成的耐除草劑之植物）包括以Clearfielf®之名稱販 5 貝者(例如玉米），當然，這些聲明也適用於具這些基因特 色或其在將來會被發展及/或販售而具有將被發展的基因 特色之植物栽培品種。 , 所列舉之植物可根據本發明，以特別有利的方式，使 用根據本發_活性化合物組合物予以處理 ，上述就活性 10 化合物組合物之較佳範圍，也適於應用於處理這些植物， 特別強調的係以明確地在本内文内提及的活性化合物組 合處理植物。 根據本發明的活性化合物組合，不僅具活性對抗植 物、衛生與儲存的產品中之有害生物，也能對抗獸醫學領 15 域之動物寄生蟲類（外-寄生物與内-寄生物），例如硬壁 • 風，軟壁風、被齋癖、葉蜗’蒼繩(整繩與紙繩），寄生繩 幼蟲，蝨子，頭蝨，羽蝨以及跳蚤，這些寄生物（蟲）包括： 兹目(Anophirida)生物，例如，盲蟲屬（Haematopinus spp·)，長顎蟲屬（Linognathus spp·)，體兹屬（Pediculus 20 spp·)，雞體羽蝨屬（Phtirus spp·)，水牛盲蝨屬（Solenopotes spp〇 ° 食毛目（Mallophagida)以及 Amblycerina 與 Ischnocerina 亞目生物，令如，Trimenopon spp·，雞羽蟲 屬（Menopon spp.)，Trinoton spp.，牛羽益屬（Bovicola -40- 200814927 spp·)，Werneckiella spp.，Lepikentron spp·，Damalina spp.， 羽兹屬（Trichodectes spp.)，貓羽兹屬（Felicola spp·)。 雙翅目（Diptera)以及長角亞目（Nematocerina)與短角 亞目（Brachycerina)生物，例如，伊蚊屬（Aedes spp·)，按蚊 5 屬（Anopheles spp·)，庫蚊屬（Culex spp·)，蚋繩（Simulium SPP.)，真蚋屬（Eusimulium spp·)，白蛉(Phlebotomus spp·)， •羅蛉屬（Lutzomyia spp.)，擬蚊蠓屬（Culicoides spp.)，斑it ，屬（Chrysops spp·)，瘤 it 屬（Hybomitra spp·)，黃 it 屬 (Atylotusspp.)，牛 it 屬（Tabanusspp·)，麻 it(Haematopota 10 spp·)，Philipomyia spp·，蜂繩(Braula spp·)，家繩屬（Musca spp·)，齒股繩(Hydrotaea spp·)，刺繩屬（Stomoxys spp)，血 繩(Haematobia spp·)，莫繩屬（Morellia spp·)，廁绳屬（Fannia spp.)，螫繩屬（Glossina spp·)，麗繩屬（Calliphora spp·)，綠 繩（Lucilia spp.)，大頭金蠅屬（Chrysomyia spp·)， is Wohifahrtia spp·，肉绳屬（Sarcophaga spp·)，鼻蠅屬（Oestrus • spp·)，皮蠅屬（Hypoderma spp·)，胃繩屬（Gasterophilus spp·)，蟲繩屬（Hippobosca spp·)，Lipoptena spp.，兹繩屬 (Melophagus spp·) o 蚤目（Siphonapterida)生物，例如，人蚤屬（Pulex spp·)， 20 櫛頭蚤屬（Ctenocephalides spp·)，鼠蚤(Xenopsylla spp·)， 葉蚤屬（Ceratophyllus spp.)。 異翅目（Heteropterida)生物，例如，臭蟲(Cimex spp·)， 吸血獵蝽屬（Triatomaspp·)，錐鼻蟲(Rhodniusspp·)，大錐 蝽（Panstrongylus spp·) 〇 -41 - 200814927 蜚蠊目（Blattarida)生物，例如，東方蜚蠊（5/加加 on·⑼如/仏），美洲大蠊⑽，德國小蠊 germimfcfl)，蜚蠊屬（Supella spp·)。 蜱蟎亞綱[Acari (Acarina)]與後-胸氣門及中-胸氣門目 5 (Meta- and Mesostigmata)生物，例如，隱緣蜱屬（Argas spp·)，純緣蜱屬（Ornithodoros spp.)，耳殘緣蜱屬（Otobius spp.)，硬蜱屬（Ixodes spp·)，花蜱屬（Amblyomma spp·)，牛 _ 蜱屬（Boophilus spp·)，矩頭蜱屬（Dermacentor spp·)，食血 蜱屬（Haemophysalisspp·)，水蜱屬（Hyalommaspp·)，Jk紅 i〇 扇頭蜱（Rhipicephalus spp·)，刺皮蜗屬（Dermanyssus spp·)，Raillietia spp·，肺刺蟎屬（Pneumonyssus spp.)，氣 囊瞒屬（Sternostoma spp·)，蜂蟹瞒(Varroa spp·)。 輻亞目[Actinedida，又稱為前氣門亞目（Prostigmata)] 與粉蜗亞目[Acaridida，又稱無氣門亞目（Astigmata)]生 15 物，例如，蜂盾蜗(Acarapis spp.)，皮毛挤蟲(Cheyletiella • spp.)，Ornithocheyletia spp·，恙蟲(Myobia spp.)，癢蜗屬 (Psorergates spp·)，螺形瞒屬（Demodex spp·)，恙蜗屬 (Trombicula spp·)，Listrophorus spp·，粗腳粉瞒（Acams spp·)，酿蜗屬（Tyrophagus spp·)，Caloglyphus spp·， 20 Hypodectes spp·，Pterolichus spp.，癢蜱屬（Psoroptes spp·)，皮癢蜗屬（Chorioptes spp.)，耳癢蜗（Otodectes spp·)，療蜗屬（Sarcoptes spp·)，頭療蜗屬（Notoedres spp·)， 膝济瞒屬（Knemidocoptes spp·)，氣囊瞒屬（Cytodites spp.)，禽皮下囊瞒屬（Laminosioptes spp·)。 -42- 200814927 根據本發明的活性化合物組合物也適用於供控制節 肢動物類以避免其騷擾農業的生產性牲畜，例如牛、綿 羊、山羊、馬、豬、驢子、路騎、水牛、兔子、雞、火雞、 鴨子、鵝及蜜蜂，其他寵物類，例如，狗、I苗、籠鳥及觀 5 賞魚，以及所謂的實驗動物，例如，倉鼠、天竺鼠、大老 鼠與小老鼠；藉由控制這些節肢動物類，可減少飼養的動 物之死亡率與減產（肉、奶、羊毛、毛皮、蛋、蜂蜜等等）， _ 藉由使用根據本發明的活性化合物組合可達更大的羥_ 效益與更容易的動物飼養。 10 根據本發明的化合物被使用於獸醫學領域及動物_ 養上，係以已知方式經由内服方式投與，使用，例如，鍵 劑，膠囊劑，飲品，飲劑，粒劑，糊劑，食團，經飼料及 栓劑；藉由非經消化道的投藥方式，例如，注射（肌肉内 的、皮下的、靜脈内的、腹膜内的，等等），經由植入、 I5 經鼻道施用，經皮膚施用，例如，浸洗或泡浴、喷灑、倒 • 入及點上、淋洗、灑粉、以及藉助於含有活性化合物之模 塑的物件，例如項圈，耳記，尾環’肢、繃帶，鞋繩，標識 裝置，等等。 當用於牛群、家禽、寵物，等等時，活性化合物組合 20 可呈調配劑（例如粉劑、乳劑、可流動的組成物）被使用， 其中包含活性化合物的量為自1至重里計’直接地或 經稀釋100至10000倍後使用，或做為化學藥浴使用。 此外，更發現，根據本發明之活性化合物組合具有強 力的殺昆蟲的作用，用於對抗會摧毁工業材料之昆蟲。 • 43- 200814927 5Rea,® (five) Jia Phossein 'such as corn, cotton, soybeans), (10) kiss [尬10 ki-xin [such as rapeseed], IMI8 (imidazole-resistant ketone) and Talk 8 (resistant to yellow wine ^ 'for example corn); The herbicide-tolerant plants (herbicide-tolerant plants bred in the traditional f formula) which may be mentioned include those which are sold under the name Clearfielf® (for example, corn). Of course, these statements also apply to the characteristics of these genes or It will be developed and/or sold in the future with plant cultivars that will be developed with genetic characteristics. The plants listed can be treated according to the invention in a particularly advantageous manner using the compositions according to the invention, which are suitable for the treatment of these plants, in particular for the preferred range of active compound compositions. It is emphasized that the plants are treated in combination with the active compounds specifically mentioned in the present text. The active compound combination according to the invention is not only active against pests in plants, sanitary and stored products, but also against animal parasites (external-parasites and endo-parasites) of the veterinary school, for example Hard wall • Wind, soft wall wind, being fasted, leaf worm 'claw rope (whole rope and paper rope), parasitic rope larvae, scorpions, head lice, feathers and fleas, these parasites (worms) include: (Anophirida) organisms, for example, Haematopinus spp., Linognathus spp., Pediculus 20 spp., Phtirus spp., buffalo blind Genus (Solenopotes spp〇° Mallophagida and Amblycerina and Ischnocerina suborder organisms, such as, Trimenopon spp., Menopon spp., Trinoton spp., Buffalo-B- 200814927 spp·), Werneckiella spp., Lepikentron spp·, Damalina spp., Trichodectes spp., Felicola spp. Diptera and Nematocerina With short horns (Brac Hycerina) organisms, for example, Aedes spp., Anopheles spp., Culex spp., Simulium SPP., Eusimulium spp. ,Pelebotomus spp., Lutzomyia spp., Culicoides spp., Chrysops spp., Hybomitra spp., yellow it Genus (Atylotusspp.), Taenusspp., Haematopota 10 spp., Philipomyia spp, Braula spp., Musca spp., Hydrotaea spp ·), Stomoxys spp, Haematobia spp., Morellia spp., Fannia spp., Glossina spp., Lily ( Calliphora spp·), Lucilia spp., Chrysomyia spp., Wohifahrtia spp·, Sarcophaga spp., Oestrus • spp·, Drosophila (Hypoderma spp.), Gasterophilus spp., Hippotosca spp., Lipoptena spp., Melophagus spp. o 蚤(Siphonapterida) organisms, for example, is a human flea (Pulex spp ·), 20 flea genus (Ctenocephalides spp ·), the rat flea (Xenopsylla spp ·), is a leaf flea (Ceratophyllus spp.). Heteropterida organisms, for example, Cimex spp., Triatomaspp., Rhodnisspp, Panstrongylus spp. 〇-41 - 200814927 (Blattarida) organisms, for example, Oriental cockroach (5/Gaga on (9) such as / 仏), American cockroach (10), German cockroach germimfcfl), genus Supella spp. [Acari (Acarina)] and the posterior-thoracic valve and the meta-and Mesostigmata organism, for example, Argas spp., Ornithodoros spp. ), Otobius spp., Ixodes spp., Amblyomma spp., Boophilus spp., Dermacentor spp. , Haemophysalisspp·, Hyalommaspp·, Rhipicephalus spp., Dermanyssus spp., Raillietia spp., P. Pneumonyssus spp.), Sternostoma spp., Varroa spp. The genus Actinedida (also known as Prostigmata) and the genus Acaridida (also known as Astigmata), for example, Acarapis spp. Cheyletiella • spp., Ornithocheyletia spp., Myobia spp., Psorergates spp., Demodex spp., Trombula spp. Listrophorus spp·, Acams spp., Tyrophagus spp., Caloglyphus spp., 20 Hypodectes spp., Pterolichus spp., Psoroptes spp., genus Chorioptes spp.), Otodectes spp., Sarcoptes spp., Notoedres spp., Knemidocoptes spp., Cytodites spp. ), Laminosioptes spp. -42- 200814927 The active compound composition according to the invention is also suitable for productive livestock for controlling arthropods to avoid harassment of agriculture, such as cattle, sheep, goats, horses, pigs, scorpions, road rides, buffalo, rabbits, Chickens, turkeys, ducks, geese and bees, other pets, such as dogs, I seedlings, cage birds and 5 fish, and so-called experimental animals, such as hamsters, guinea pigs, big mice and small mice; Controlling these arthropods can reduce the mortality and production of the reared animals (meat, milk, wool, fur, eggs, honey, etc.), _ by using the active compound combination according to the invention to achieve greater hydroxylity Benefits and easier animal feeding. 10 The compounds according to the invention are used in the field of veterinary medicine and in animal feeding, by means of internal administration in a known manner, using, for example, a key, a capsule, a drink, a drink, a granule, a paste, Feeding group, feed and suppository; by non-digestive administration, for example, injection (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), via implantation, I5 nasal administration , applied by the skin, for example, dipping or bathing, spraying, pouring and spotting, rinsing, powdering, and by means of molded articles containing active compounds, such as collars, ear notes, tail rings' Limbs, bandages, shoe cords, identification devices, and more. When used in cattle, poultry, pets, and the like, the active compound combination 20 can be used as a formulating agent (e.g., a powder, an emulsion, a flowable composition), wherein the amount of the active compound is from 1 to liters. Use directly or diluted 100 to 10,000 times, or as a chemical bath. Furthermore, it has been found that the active compound combination according to the invention has a strong insecticidal action against insects which destroy industrial materials. • 43- 200814927 5

10 1510 15

20 下面的昆蟲類為可作為被舉例且為較佳的實例，但不 僅限於此： 甲蟲類，例如，家天牛办办w/ws)，pilosis 天牛，具斑竊蠹punctatum)，紅毛竊蠹(Xestobium rufovillosum) y Ptilinus peeticornis ^ Dendrobium pertinex j 氣蠢（Ernobius mollis)，Priobium carpini，褐粉蠢(Lyctus ，非洲粉蠹(々Fciws β/WcawMS)，平頭粉橐（办以似 planicollis)，Lyctus linearis，Lyctus pubescens，Trogoxylon aequale，Minthes rugicollis，蠢屬（Xyleborus spec.)， Tryptodendron spec·咖口非黑長橐monachus)， Bostrychus capucins，Heterobostrychus brunneus，1 蠢取 (Sinoxylon spec.)，竹 1 蠢魇（Dinoderus minuteus);膜翅類(Hymenopterans)生物，例如，鋼青小樹蜂，樅大樹蜂（C/rocerws gz’goy)、t/rocerMS gigfls taignus , Urocerus augur; 白議類，例如，歐洲木白蟻(尺^/〇化广《2以/7心/(：〇//仏）， 澳洲白蟻kev/s)，沙漠白蟻 indicola) ^ 黃胸散白壤（Reticulitermes flavipes)， Reticulitermes santonensis，Reticulitermes lucifugus，：展满 台織 QMastotermes darwiniensis、，古白鐵(Zootermopsis nevadensis)，台灣家白壤(Coptotermes formosanus)·，西洋衣魚類，例如，西洋衣魚以cc/mrzVm) 〇在此所謂的工業材料，可理解的是指無生命之材料， 例如，較佳地係指塑料類、粘著劑類、漿糊類、紙類與卡 -44- 200814927 紙、皮^木料與加卫的木製品及塗裝組成物。 二：組成物’適當的，可再包含另外的殺昆 及’適料，另外之—❹種殺真8劑類。 520 The following insects are exemplified and preferred examples, but are not limited to this: beetles, for example, housewife dow w/ws), pilosis beetle, punctatum, red hair Xestobium rufovillosum y Ptilinus peeticornis ^ Dendrobium pertinex j Ernobius mollis, Priobium carpini, brown stupid (Lyctus, African Frucs β/WcawMS), flat-headed whitefly (like planicollis), Lyctus linearis, Lyctus pubescens, Trogoxylon aequale, Minthes rugicollis, Xyleborus spec., Tryptodendron spec, non-black scorpion monachus, Bostrychus capucins, Heterobostrychus brunneus, 1 Sinoxylon spec., bamboo 1 stupid Dinoderus minuteus; Hymenopterans, for example, A. sylvestris, C/rocerws gz'goy, t/rocerMS gigfls taignus, Urocerus augur; White, for example, European wood Termites (feet^/〇化广"2 to /7 hearts/(:〇//仏), Australian termites kev/s), desert termites indicola) ^Reticulitermes flavipes, Reticuliter Mes santonensis, Reticulitermes lucifugus, full of woven QMastotermes darwiniensis, Zotermopsis nevadensis, Taiwanese white soil (Coptotermes formosanus), western squid, for example, western squid cc/mrzVm) Industrial materials, understood to mean inanimate materials, for example, preferably plastics, adhesives, pastes, papers and cards -44-200814927 paper, leather, wood and reinforced Wood products and coating compositions. Second: the composition 'appropriate, can be further included in the other killing and 'suitable materials, in addition, ❹ 杀 杀 kill 8 doses. 5

10 15 20 油ίϋ可ϊ之額外添加物而言，可參考上述提及的殺蟲 劑類及殺真菌劑類。 根據本發明的活性化合物組合同樣的可被應用於供 ί護與海水或㈣味的水接觸之物體，特別是船身，圍 屏’網子’建築物’繫船用具及信號系統，用於對抗附著 物之 滿。 此外，根據本發明的活性化合物組合，單獨或併用其 他的活，化合物下，可被用於作為抗生物附著劑。 在豕戶内的、衛生的及儲存的_產物的保護方面，此活 性化合物組合物也適於供防治動物有害生物，特別是常出 =封閉空間内(例如，住處、卫場大廳、辦公室、車庫 等等地方）之昆蟲、蜘蛛及蟎類，為控制這些有害動物， 它們可被單獨地使用或併用其他的活性化合物及辅助劑 於供豕庭居所使用之殺昆蟲的產品内，它們具有活性對抗 敏感性的及具抗性的品種以及其所有的發育階段，這些有 害生物包括： 蝎類（Scorpionidea)生物，例如，仇仏⑽此也⑽似。 蜱蟎目（Acarina)生物，例如，波斯隱喙蜱 persicus)，Argas reWexus，苢蓿苔螨(BryoMa ssp )，雞灰 刺蟎（Derm⑽;ga/.fle)，家嗜甜蟎（G/yc/p/mgt^ ，鈍緣瞒（(9/τπ·从οί/οη/Α爪⑽^如），企紅扇頭蜱 -45- 200814927 (Rhipicephalus sanguineus) ， 恙、虫茜 (Trombicula alfreddugesi) ， Neutrombicula autumnalis ， Dermatophagoides pteronissimus ， Dermatophagoides forinae ° 5For the additional additives of 10 15 20 oil, refer to the above-mentioned insecticides and fungicides. The active compound combinations according to the invention can likewise be applied to objects which are in contact with sea water or (four) flavors of water, in particular the hull, the screen 'nets' buildings, the ship's tools and signalling systems, for combating The attachment is full. Furthermore, the active compound combinations according to the invention, either alone or in combination with other living compounds, can be used as anti-bioadhesive agents. The active compound composition is also suitable for the control of animal pests in the protection of the household, sanitary and stored products, in particular in the enclosed space (eg, residence, guard hall, office, In the garage, etc., insects, spiders and mites, in order to control these harmful animals, they can be used alone or in combination with other active compounds and adjuvants in the insecticidal products used in the residences of the courts, they are active Against the sensitive and resistant varieties and all their developmental stages, these pests include: Scorpionidea organisms, for example, hate (10) This is also (10). Acarina creatures, for example, Persian conceicus, Argas reWexus, BryoMa ssp, chicken gray hedgehog (Derm(10); ga/.fle), home sweet potato (G/yc) /p/mgt^ , blunt edge 瞒 ((9/τπ·from οί/οη/Α爪(10)^如), 赤红头头蜱-45- 200814927 (Rhipicephalus sanguineus), 恙 恙, 茜 (Trombicula alfreddugesi), Neutrombicula autumnalis , Dermatophagoides pteronissimus , Dermatophagoides forinae ° 5

10 1510 15

20 虫知蛛類（Araneae)生物，例如，Aviculariidae，檢蛛 (Araneidae); 盲蛛目（Opiliones)生物，例如，擬缴(尸此wdoscorpzowe·? chelifer) ， Pseudoscorpiones cheiridium ， ^ ^ {Opiliones phalangium) ° 等足目（Isopoda)生物，例如，球鼠婦（潮蟲 asellus)，黑、觀蟲XJPorcellio scaber) 〇 倍足綱（Diplopoda)生物，例如，具斑馬陸（万/aWw/ws guttulatus) ^ Polydesmus spp.; 唇足綱（Chilopoda)生物，例如，食果地娱讼 響·）。 總尾綱目（Zygentoma)，例如，蠹蟲 spp.)，西洋农 0、(Lepisma saccharina) ，Lepismodes inquilinus ° 蜚蠊目（Blattaria)生物，例如，東方蜚蠊（及/αίία oWenia/fes)、德國小蠊germaw/ciz)，阿昔耐蜚蠊 (Blattella asahinai)，馬得权豐蟣：(Leucophaea maderae)， Panchlora spp·，木蠊屬（Parcoblatta spp·)，澳洲大蠊 (Periplaneta australasiae)，美洲大赚（Periplaneta dmerfc⑽a)，褐色大蠊CPeWp/imeM ，烟色大蠊 -46- 200814927 (Periplanetafuliginosa)，^M^^(Supellalongipalpa)。 跳躍目（Saltatoria)生物，例如，家蟋蟀 domesticus) 〇 革翅目（Dermaptera)生物，例如，歐洲球螋 auricularia) ° 等翅目（Isoptera)生物，例如，普通幹木白蟻類 (Kalotermes spp·)，網白蟻類（Reticulitermes spp·)。20 Araneae organisms, for example, Aviculariidae, Araneidae; Opiliones, for example, to be paid (the body of this wdoscorpzowe·? chelifer), Pseudoscorpiones cheiridium, ^ ^ {Opiliones phalangium) ° Isopoda creatures, for example, the squirrel (the worm), black, larvae XJPorcellio scaber), the genus Diplopoda, for example, with zebra land (wan/aWw/ws guttulatus) ^ Polydesmus spp.; Chilopoda creatures, for example, eating fruit and entertainment. Zygentoma, for example, aphid spp.), Lepisma saccharina, Lepismodes inquilinus ° Blattaria, for example, Oriental cockroach (and /αίία oWenia/fes), German small蠊germaw/ciz), Blattella asahinai, (Leucophaea maderae), Panchlora spp., Parcoblatta spp., Periplaneta australasiae, Americas Earn (Periplaneta dmerfc (10)a), brown cockroach CPeWp/imeM, smoky cockroach -46- 200814927 (Periplanetafuliginosa), ^M^^ (Supellalongipalpa). Saltatoria organisms, for example, domesticus, Dermaptera organisms, for example, European auricularia ° Isoptera organisms, for example, common dry wood termites (Kalotermes spp.) , Reticulitermes spp.

10 1510 15

20 嗔蟲目（Psocoptera)生物，例如，書蝨屬（Lepinatus spp·)，書歲(Liposcelis spp·)。 鞘翅目（Coleoptera)生物，例如，皮蠹屬（Anthremis spp.) ^ (Attagenus spp.) M (Dermestes spp〇 ^ 長頭谷盜（Latheticus oryzae)，郭公蟲屬（Necrobia spp·)， 珠曱屬（Ptinus spp.)，家竊蠹i/omzWed)，谷象 (Sitophilus granaries)，糸 I {Sitophilus oryzae)，玉糸 I (Sitophilus zeamais)，藥材谷盜(jSYegO厶o 雙翅目（Diptera)生物，例如，埃及伊蚊 ciegypti) ^ 白紋伊蚊albopictus) ’ Aedes ，按蚊屬（Anopheles spp.)，紅頭麗繩 (Calliphora erythrocephala)，Chrysozona pluvialis，瓦帶淡 色庫妓（Cw/ex quinquefasciatus)，炎音尊蚊（Culex ，Cw/ex ，果蠅屬spp.)，厠繩 {Fannia canicularis)，家現{Musca domestica)，Phlebotomus spp. J ^ ^ ^(Sarcophaga carnaria) j Simulium spp. » (Stomoxys calcitrans)，歡洲大故(Tipula paludosa); «47- 200814927 鱗翅目（Lepidoptera)生物，例如，小堪模（Jc/zrc^fl grisella)，大後螺（Galleria mellonella)，印良谷堪(Plodia ，穀蛾（Γζ·?2ββ c/(9ace//a)，網衣蛾（77wea pellionella)，袋衣味(Tineola bisselliella) 〇 5 蚤目（Siphonaptera)生物，例如，狗櫛頭蚤 (Ctenocephalides canis)，$法櫛頭蚤（Cienocephalides /e/z\s)，人蚤，穿皮潛蚤（Tunga;?e«ein2/^)， 鲁 I 方 H(Xenopsylla cheopis) 〇 膜翅目（Hymenoptera)生物，例如，大黑蟻 10 herculeanus)，禀、萆場XLasius fuligirtosus)，警通黑、織(Lasius niger) ^ Lasius umbratus ^ 廚織(Monomorium pharaonis)， Paravespula spp·，鉞道壤(Tetramorium caespitum) 〇 兹目（Anoplura)生物，例如，頭兹CPei/z’ew/⑽ capitis)，後叙[Pediculus humanus corporis)，天疮屬 15 (Pemphigus spp)，Phylloera vastatrix，德裂（Phthirus • pubis)。 異翅亞目（Heteroptera)生物，例如，臭蟲（C7mex hemipterus)，臭 HGimex lectularius) ’ Rhodimis prolixus， 吸血獵培（TWaMmiz 。 2〇 在家用的殺蟲劑領域中，它們被單獨使用或併用其他 適當的活性化合物，例如，併用磷酸酯類、胺基甲酸酯類、 擬除蟲菊酯類、新尼古丁類、生長調節劑或其他類已知的 殺昆轰劑。 它們被調配成下列型式使用：氣霧劑，非加壓的喷霧 •48- 200814927 劑，例如泵送的喷灑劑及霧化喷灑劑，自動20 Psocoptera organisms, for example, Lepinatus spp., Liposcelis spp. Coleoptera, for example, Anthremis spp. ^ (Attagenus spp.) M (Dermestes spp〇^ Latheticus oryzae, Necrobia spp., genus (Ptinus spp.), housewife 蠹i/omzWed), Sitophilus granaries, 糸I {Sitophilus oryzae), itI (Sitophilus zeamais), 药谷谷盗 (jSYegO厶o Diptera, For example, Aedes aegypti ciegypti) Aedes albopictus 'Aedes, Anopheles spp., Calliphora erythrocephala, Chrysozona pluvialis, Cw/ex quinquefasciatus, inflammation Acoustic mosquito (Culex, Cw/ex, Drosophila spp.), toilet rope {Fannia canicularis), home now {Musca domestica), Phlebotomus spp. J ^ ^ ^(Sarcophaga carnaria) j Simulium spp. » (Stomoxys calcitrans ), Tipula paludosa; «47- 200814927 Lepidoptera, for example, Jc/zrc^fl grisella, Galleria mellonella, Pludia , moth (Γζ·?2ββ c/(9ace//a), Netweed moth (77wea pellionella), Tineola bisselliella 〇5 Siphonaptera creature, for example, Ctenocephalides canis, Cienocephalides /e/z\s People, wearing a leather snorkel (Tunga;?e«ein2/^), Lueno H (Henosylla cheopis) Hymenoptera, for example, the big black ant 10 herculeanus), 禀, 萆 XL XL XL XL XL XL XL XL ), police, Lasius niger ^ Lasius umbratus ^ Monomorium pharaonis, Paravespula spp·, Tetramorium caespitum, Anoplura creatures, for example, heads CPei/z'ew /(10) capitis), later (Pediculus humanus corporis), Pemphigus spp, Phylloera vastatrix, Phthirus • pubis. Heteroptera, for example, C7mex hemipterus, HGimex lectularius) Rhodimis prolixus, TWaMmiz. 2 In the field of pesticides for household use, they are used alone or in combination with other appropriate Active compounds, for example, in combination with phosphates, urethanes, pyrethroids, neonicotins, growth regulators or other known killing agents. They are formulated into the following forms: Aerosol, non-pressurized spray • 48- 200814927 agents, such as pumped sprays and atomized sprays, automatic

，，泡沫劑，凝膠，帶有由纖維素或聚合物作匕:、統J 器薄片的蒸化器產物，液體蒸化物，凝膠 :的療發 维子耐& ^ W寻粗翁化物， 5 [式_的蒸化物’不耗能的，或被動式蒸發系統，枯蛾 、、、氏’捕峨袋及捕蛾凝膠，做成顆粒或粉塵物，置於供散佈 的誘餌中或置於誘餌裝備站内使用。 _ 【實施方式】 1〇 根據本發明的活性化合物組合物之良好的殺昆轰的 及殺蟎的活性，由隨後的實例予以說明，其中個別的活性 化合物顧現弱的作用，組合物所呈現的作用遠超過其個別 作用之總和。 當活性化合物組合物在殺昆蟲的及殺蟎的作用上總 疋呈現超過其個別的活性化合物的作用之總和時，為具有 15 協乘效果。 ^ _ 對於所給含兩種活性化合物的組合物之被預期的活 性，可根據 S.R· Colby 的算式(Weeds 以（1967)，2〇_22)， 被計算如下： 如果, foaming agent, gel, with a vaporizer product made of cellulose or polymer as a 匕:, a J slice, liquid steamed, gel: the treatment of vascular resistance & ^ W seeking rough Compound, 5 [form of steamed product of the formula] is not energy-consuming, or a passive evaporation system, a moth, a 'strap' bag, and a moth-killing gel, made into granules or dust, placed in a bait for distribution. Or use it in a bait equipment station. _ [Embodiment] 1 The good killing and killing activity of the active compound composition according to the present invention is illustrated by the following examples, in which individual active compounds take into account the weak effect, the composition is presented Its role far exceeds the sum of its individual effects. When the active compound composition exhibits more than the sum of the effects of its individual active compounds in insecticidal and acaricidal action, it has a 15 synergistic effect. ^ _ The expected activity for a given composition containing two active compounds can be calculated as follows according to the formula of S.R. Colby (Weeds (1967), 2〇_22):

2Q X 代表當以组克/公頃的施用率或以nippm的濃度下施 用活性化合物A時，未處理的對照組之殺死率百分比 (%)， Y 代表當以辽克/公頃的施用率或以n ppm的濃度下施 用活性化合物B時，未處理的對照組之殺死率百分比 -49, 200814927 (%)， E 代表當以m及il克/公頃的施用率或以m及n ppm的 濃度下施用活性化合物A與B時，未處理的對照組之 殺死率百分比，2Q X represents the percentage (%) of the kill rate of the untreated control group when the active compound A is applied at a rate of application of g/ha or at a concentration of nippm, and Y represents the application rate at the gram/ha or Percent kill rate of untreated control group at -5, 200814927 (%), E represents the application rate at m and il g/ha or at m and n ppm when active compound B is applied at a concentration of n ppm Percentage of kill rate in untreated control groups when active compounds A and B were administered at concentrations,

X.Y 貝E 二 X + Y ———一 100X.Y 贝 E II X + Y ———一 100

I 10 如果真正的殺昆蟲或殺蟎之殺死率超過計算得的數 值時，則組合物的作用係超加成的，即，出現一種協乘效 果，此情況中，真正被觀察到的殺死率需超過使用上述公 式計算得之被預期的殺死率（E)。I 10 If the true killing rate of insecticides or killings exceeds the calculated value, then the effect of the composition is superadditive, ie, a synergistic effect occurs, in which case the truly observed killing occurs. The death rate needs to exceed the expected kill rate (E) calculated using the above formula.

15 實例A 桃財試驗 _ 溶劑：7份重的二甲基甲醯胺 乳化劑：2份重的烧基芳基聚甘醇醚 為產生適當的活性化合物之配製劑，將1份重的活性 20 化合物與所述量的溶劑及乳化劑混合，再以含乳化劑的水 將此濃縮物稀釋至所要的濃度。 將已嚴重感染了綠桃財(Mjzws 的捲心菜葉 子(万raw/cfl oleracea)浸入所要濃度之活性化合物之配製 劑溶液内加以處理。 25 經過一段想要的時間後，測定殺死的百分比，100% -50- 200814927 代表全部的蚜蟲已被殺死；〇%代表沒有蚜蟲被殺死，將測 定的殺死率代入Colby公式（見表單1)。 此試驗中，例如，根據所述施用率之下述的活性化合 物混合物，相比較於個別地施用活性化合物，顯現協乘地 5 增加活性。 表A，第1頁 傷害植物之昆蟲 $ji^(Myzus persicae)^^k 活性化合物 濃度(ppm) 第1天後之殺死率ί%) 化合物(la) 0.8 55 化合物(lb) 4 40 赛滅寧(cypermethrin) 0.032 10 λ-赛洛寧 (lambda-cyhalothrin) 0.16 0 根據本發明的: (la) + 赛滅寧（25:1) 0·8 + 0.032 實測得值*計算得值** 85 59.5 根據本發明的： (lb) + λ-賽洛寧 (25 : 1) 4 + 0.16 實測得值*計算得值** 85 40 10 *實测得值=實際測得的活性 **計算得值=使用Colby的公式計算得之活性15 Example A Peach Test _ Solvent: 7 parts by weight of dimethylformamide emulsifier: 2 parts by weight of aryl aryl polyglycol ether to give a suitable active compound formulation, 1 part by weight of activity 20 The compound is mixed with the amount of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing an emulsifier. The green peach (Mjzws's cabbage leaf (wanraw/cfl oleracea) is immersed in a formulation solution of the active compound at the desired concentration. 25 After a desired period of time, the percentage of kill is determined, 100 % -50- 200814927 means that all the mites have been killed; 〇% means that no mites have been killed, and the determined kill rate is substituted into the Colby formula (see Form 1). In this test, for example, according to the application rate The active compound mixture described below exhibits a synergistic increase in activity compared to the individual application of the active compound. Table A, page 1 Insecticide insects $ji^(Myzus persicae)^^k Active compound concentration (ppm) Kill rate after day 1 %) Compound (la) 0.8 55 Compound (lb) 4 40 cypermethrin 0.032 10 λ-cylonine (lambda-cyhalothrin) 0.16 0 According to the invention: (la + 赛灭宁(25:1) 0·8 + 0.032 measured value * calculated value ** 85 59.5 According to the invention: (lb) + λ-cylonin (25: 1) 4 + 0.16 Value * Calculated value ** 85 40 10 * Measured value = Actual measured activity ** Calculation = Value calculated using Colby's formula of the active

實例B 辣裉氣葉赢(Phaedon cochleariae)幼義議1驗 -51 - 200814927 溶劑：7份重的二曱基曱醯胺 乳化劑：2份重的烧基芳基聚甘醇醚 為產生適當的活性化合物之配製劑，將1份重的活性 化合物與所述量的溶劑及乳化劑混合，再以含乳化劑之水 將此濃縮物稀釋至所要的濃度。 將捲心菜葉子(价o/eracea)浸入所要濃度之、、舌 性化合物之配製劑溶液後，在葉子還潤濕的時候，放置上 芬菜甲蟲(尸的幼蟲。 10 15Example B Phaedon cochleariae (1) -51 - 200814927 Solvent: 7 parts by weight of dimethyl decylamine emulsifier: 2 parts by weight of aryl aryl polyglycol ether For the formulation of the active compound, 1 part by weight of the active compound is mixed with the amount of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier. After immersing the cabbage leaves (price o/eracea) in the formulation solution of the desired concentration of the tongue compound, place the fennel beetle (the larva of the corpse when the leaves are still moisturized. 10 15

經過一段想要的時間後，測定殺死的百分比，1 〇〇% 代表全部的甲蟲幼蟲均已被殺死；0%代表沒有甲蟲幼蟲 被殺死，將測定的殺死率代入Colby公式（見表單丨）。 此試驗中，根據所述施用率之下述的活性化合物混合 物，相比較於個別地施用活性化合物，顯現協乘地增加活 性0 表B，第1頁 傷害植物之昆蟲· 辣根猿葉A(Phaedon cochleariae)幼蟲試驗 活性化合物 濃度(ppm) 篦：？夭後之殺死率(％) 化合物(la) 100 35 20 0 化合物(lb) 20 11 赛滅寧(cypermettirin) 4 35 第滅寧(deltamethrin) 0.8 44 β-赛扶寧(cyfluthrin) 4 80 -52- 200814927 根據本發明的： 實測得值* 計算得值** (la) + 赛滅寧（25:1) 100 + 4 90 57.75 根據本發明的： 實測得值* 計算得值** (la) + 第滅寧（25: 1) 20 + 0.8 94 44 根據本發明的： 實測得值* 計算得值** (Ib)+ 第滅寧（25: 1) 20 + 0.8 78 50.16 根據本發明的： 實测得值* 計算得值μ (Ia)+P-赛扶寧（5··1) 20 + 4 95 80 *實測得值=實際測得的活性 **計算得值==使用Colby的公式計算得之活性 表B，第2頁 5 傷害植物之昆蟲 _ ^{Phaedon cochleariae)^j 活性化合物 濃度(ppm) 第3天後之殺死率(％) 化合物(la) 100 25 化合物(lb) 20 10 γ-赛洛寧 4 45 (gamma-cyhalothrin) 0.8 30 λ_赛洛寧 4 65 (lambda-cyhalothrin) 0.8 10 根據本發明的： 實測得值* 計算得值μ (la)+ γ-赛洛寧（25: 1) 100 + 4 100 58.75 根據本發明的： 實測得值4 計算得值μ (11>) + γ-賽洛寧（25: 1) 20 + 0.8 50 37 200814927 根據本發明的： 實測得值* 計算得值** (la) + λ-赛洛寧（25: 1) 100 + 4 100 73.75 根據本發明的： 實測得值* 計算得值** (Ι1)) + λ-赛洛寧（25: 1) 20 + 0.8 55 19 *實測得值=實際測得的活性 **計算得值==使用Colby的公式計算得之活性After a desired period of time, the percentage of kills is determined, 1 〇〇% means that all beetle larvae have been killed; 0% means no beetle larvae are killed, and the determined kill rate is substituted into the Colby formula (see Form 丨). In this test, the following active compound mixture according to the application rate shows a synergistic increase in activity compared to the individual application of the active compound. Table B, page 1 Insect plant insects • Horseradish leaf A ( Phaedon cochleariae) Larval test active compound concentration (ppm) 篦:? Killing rate after sputum (%) Compound (la) 100 35 20 0 Compound (lb) 20 11 cypermettirin 4 35 deltamethrin 0.8 44 β-cyfluthrin 4 80 - 52- 200814927 According to the invention: measured value * calculated value ** (la) + 赛宁宁 (25:1) 100 + 4 90 57.75 According to the invention: measured value * calculated value ** (la + 灭灭宁(25: 1) 20 + 0.8 94 44 According to the invention: measured value * calculated value ** (Ib) + dinning (25: 1) 20 + 0.8 78 50.16 according to the invention : Measured value * Calculated value μ (Ia) + P- Sai Fanning (5··1) 20 + 4 95 80 * Measured value = Actual measured activity ** Calculated value == Using Colby Activity calculated by the formula Table B, page 2 5 Insects that damage plants _ ^{Phaedon cochleariae)^j Active compound concentration (ppm) Kill rate after day 3 (%) Compound (la) 100 25 Compound (lb 20 10 γ-赛洛宁 4 45 (gamma-cyhalothrin) 0.8 30 λ_赛洛宁 4 65 (lambda-cyhalothrin) 0.8 10 According to the invention: measured value * calculated value μ (la) + γ- Xeron (25: 1) 100 + 4 100 58.75 according to the invention: measured value 4 calculated value μ (11 >) + γ-cylonine (25: 1) 20 + 0.8 50 37 200814927 According to the invention: measured value * calculated Value ** (la) + λ-cylonin (25: 1) 100 + 4 100 73.75 According to the invention: measured value * calculated value ** (Ι1)) + λ-cylonin (25: 1 ) 20 + 0.8 55 19 * Measured value = actual measured activity ** calculated value = = activity calculated using Colby's formula

-54--54-

Claims (1)

200814927 十、申請專利範圍： 1. 一種活性化合物組合物，包含至少一種的式(I)之化合物200814927 X. Patent Application Range: 1. An active compound composition comprising at least one compound of formula (I) N——RN——R (D 其中 ίο R 代表甲基或環丙基， 以及至少一種的挑選自包括下述之化合物： 1.阿納寧（acrinathrin)(D where ίο R represents methyl or cyclopropyl, and at least one selected from the group consisting of: 1. arrinathrin 2. α·賽滅寧（alpha-cypermethrin)2. alpha-cypermethin 3. β-赛扶寧（betacyfluthrin) -55- 2008149273. β-赛康宁 (betacyfluthrin) -55- 200814927 4· γ-賽洛寧（gamma-cyhalothrin)4· γ-cylonin (gamma-cyhalothrin) 10 5 ·賽滅寧(cypermethrin) 〇 CN10 5 ·赛杀宁(cypermethrin) 〇 CN 1515 6.第滅寧(deltamethrin)6. Dimensions (deltamethrin) 20 7.益化利（esfenvalerate)20 7. Yissenvale (esfenvalerate) H3C 八 ch3 -56- σ°Ό 〇/^CN 200814927 8.依芬寧（ethofenprox)H3C 八 ch3 -56- σ°Ό 〇/^CN 200814927 8. Efenine (ethofenprox) 5 9.芬普寧（fenpropathrin)5 9. Fenpanning (fenpropathrin) 10 1〇·氰戊菊醋（fenvalerate)10 1〇· fenvalerate (fenvalerate) 1515 11 ·護賽寧（flucythrinate)11 · 赛赛宁(flucythrinate) 20 12. λ-賽洛寧（lambda_cyhalothrin) -57- 20081492720 12. λ-赛洛宁 (lambda_cyhalothrin) -57- 200814927 13.百滅寧（permethrin)13.百因宁(permethrin) 10 14.套福化利（taufluvalinate) 1510 14. Set of taufluvalinate 15 Ό 15 ·泰滅寧(tralomethrin) Br,CΌ 15 · tralomethrin Br, C 20 16. zeta-賽滅寧（zeta-cypermethrin) -58- 200814927 Cl X20 16. zeta-zepering (zeta-cypermethrin) -58- 200814927 Cl X 17 ·賽扶寧(cyfluthrin) w n17 ·cyfluthrin w n 18.畢芬寧(bifenthrin) w n18. bifenthrin w n 15 19·環普寧（cycloprothrin) Cl15 19·cycloprothrin Cl 20 och2ch320 och2ch3 -59- 200814927 20.伊伏砍連特（eflusilanate)-59- 200814927 20. Evlusilanate 21 ·福务普（fubfenprox)21 · Fu Fu (fubfenprox) 22 ·除蟲菊精(pyrethrin)22 · Pyrethrin (pyrethrin) 15 20 Ri = -CH=CH2 或-CH3 或-CH2CH3 23.列滅寧(resmethrin)15 20 Ri = -CH=CH2 or -CH3 or -CH2CH3 23. Resmethrin -60- 200814927 以及 24·七氟菊酯（tefluthrin)-60- 200814927 and 24·tetrafluthrin (tefluthrin) ίο 15 20 2. 一種根據申請專利範圍第1項中所定義的活性化合 合物用於防治動物有害生物之用途。 ϋ ! 4· 一種用於防治動物有害生物之方法’特徵為，使用 申請專利範圍第1項中定義之活性化合物組合物作^於 動物有害生物及/或彼等的居住環境及/或種子上。 、 根據申請專利範圍第3項的方法，特徵為，使用一種式 I的活性化合物以及一種1至24類的擬除蟲菊酯類 (pyrethroids)同時地作用於種子上。 、 5·根據申請專利範圍第3項的方法，特徵為，使用一種式 I的活性化合物以及一種丨至24類的擬除蟲菊酯類 (pyrethroids)在不同的時間點下作用於種子上。 6， 一種製備殺蟲的及殺蟎的組合物之方法，特點為，將根 據申請專利範圍第1項中定義之活性化合物組合物與展 延劑及/或界面活性劑混合。 7· 一種根據申請專利範圍第1項的活性化合物組合物的用 途，係用於供處理種子。 8· 一種根據申請專利範圍第1項的活性化合物組合物的用 -61 - 200814927 途，係用於供處理轉殖基因植物。 9· 一種根據申請專利範圍第1項的活性化合物組合物的用 返，係用於供處理轉殖基因植物之種子。 5Ίο 15 20 2. A use of an active compound as defined in claim 1 of the patent application for controlling animal pests. ϋ ! 4 A method for controlling animal pests is characterized by using the active compound composition as defined in claim 1 for use in animal pests and/or their living environment and/or seeds. . According to the method of claim 3, it is characterized in that an active compound of the formula I and a pyrethroid of from 1 to 24 are simultaneously applied to the seed. 5. The method according to item 3 of the patent application, characterized in that an active compound of the formula I and a pyrethroids of from 24 to 24 are applied to the seed at different time points. A method for preparing an insecticidal and acaricidal composition, characterized in that an active compound composition as defined in claim 1 of the patent application is mixed with a stretching agent and/or a surfactant. 7. Use of an active compound composition according to claim 1 of the patent application for the treatment of seeds. 8. A method for the treatment of a transgenic plant according to the method of claim 1, wherein the active compound composition is used in the treatment of the transgenic plant. 9. A use of an active compound composition according to claim 1 of the scope of the patent application for the treatment of seeds of a transgenic plant. 5 10 10· —種以根據申請專利範圍第1項的活性化合物組合物處 理過的種子。 η·根據申請專利範圍第10項的種子，其係已同時地以一種 式I的活性化合物及〗至24中一種擬除蟲菊酯類 (pyrethroids)處理過。 、 已在不同的時間 中一種擬除蟲菊 12.根據申請專利範圍第1〇項的種子，其係 點下經一種式I的活性化合物及1至24 酯類(pyrethroids)處理過。10 10 - A seed treated with the active compound composition according to claim 1 of the patent application. η. According to the seed of claim 10, the seed has been treated with an active compound of the formula I and a pyrethroids of 24 to 24 simultaneously. A pyrethrum that has been treated at different times. 12. The seed according to the first aspect of the patent application is treated with an active compound of the formula I and 1 to 24 esters (pyrethroids). -62- 200814927 七、指定代表圖： .(一）本案指定代表圖為：第（無）圖。 (二）本代表圖之元件符號簡單說明： 益 〇、Λ 八、本案若有化學式時，請揭示最能顯示發明特徵的化學式： 無-62- 200814927 VII. Designation of Representative Representatives: (1) The representative representative of the case is: (No). (2) A brief description of the symbol of the representative figure: Yi 〇, Λ VIII. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention: