TW200738734A - Benzoate salt of 4-(5-methyl-oxazolo[4,5-b]pyridin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane - Google Patents

Benzoate salt of 4-(5-methyl-oxazolo[4,5-b]pyridin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane

Info

Publication number
TW200738734A
TW200738734A TW095128888A TW95128888A TW200738734A TW 200738734 A TW200738734 A TW 200738734A TW 095128888 A TW095128888 A TW 095128888A TW 95128888 A TW95128888 A TW 95128888A TW 200738734 A TW200738734 A TW 200738734A
Authority
TW
Taiwan
Prior art keywords
nonane
benzoate salt
oxazolo
diaza
bicyclo
Prior art date
Application number
TW095128888A
Other languages
Chinese (zh)
Inventor
Allen Jacob Duplantier
Kenneth George Kraus
Bruce Nelsen Rogers
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of TW200738734A publication Critical patent/TW200738734A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The present invention provides a benzoate salt of Formula I: Formula I is also known as 4-(5-methyloxazolo[4,5-b]pyridine-2-yl)-1,4-diazabicyclo[3.2.2]nonane. The benzoate salt of the invention is useful in the treatment of schizophrenia and Alzheimer's Disease. It is particularly of use in the treatment of cognitive deficits associated with schizophrenia, cognitive and attention deficit symptoms of Alzheimer's Disease, and neurodegeneration associated with Alzheimer's Disease.
TW095128888A 2005-08-08 2006-08-07 Benzoate salt of 4-(5-methyl-oxazolo[4,5-b]pyridin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane TW200738734A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70660105P 2005-08-08 2005-08-08

Publications (1)

Publication Number Publication Date
TW200738734A true TW200738734A (en) 2007-10-16

Family

ID=37398316

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095128888A TW200738734A (en) 2005-08-08 2006-08-07 Benzoate salt of 4-(5-methyl-oxazolo[4,5-b]pyridin-2-yl)-1,4-diaza-bicyclo[3.2.2]nonane

Country Status (6)

Country Link
AR (1) AR055111A1 (en)
DO (1) DOP2006000185A (en)
NL (1) NL1032286C2 (en)
TW (1) TW200738734A (en)
UY (1) UY29731A1 (en)
WO (1) WO2007017750A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009113950A1 (en) * 2008-03-10 2009-09-17 Astrazeneca Ab Therapeutic combinations of (a) an antipsychotic and (b) an alpha-4/beta-2 (a4b2)-neuronal nicotinic receptor agonist
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN115813887A (en) 2016-12-20 2023-03-21 罗曼治疗***股份公司 Transdermal therapeutic system comprising asenapine
US11337932B2 (en) 2016-12-20 2022-05-24 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
CN107188900B (en) * 2017-05-27 2019-09-06 北京师范大学 The ligand compound of alpha 7 nicotinic acetylcholine receptors and its application
CA3067938A1 (en) 2017-06-26 2019-01-03 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
KR20210022656A (en) 2018-06-20 2021-03-03 에르테에스 로만 테라피-시스테메 아게 Transdermal treatment system containing acenapine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020086871A1 (en) * 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders
JP2007516275A (en) * 2003-12-23 2007-06-21 ファイザー・プロダクツ・インク Therapeutic combinations for cognitive enhancement and psychotic disorders

Also Published As

Publication number Publication date
NL1032286A1 (en) 2007-02-09
WO2007017750A1 (en) 2007-02-15
UY29731A1 (en) 2007-03-30
DOP2006000185A (en) 2007-03-31
NL1032286C2 (en) 2007-08-07
AR055111A1 (en) 2007-08-08

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