TW200704778A - Screening using polarization anisotropy in fret emissions - Google Patents
Screening using polarization anisotropy in fret emissionsInfo
- Publication number
- TW200704778A TW200704778A TW095111992A TW95111992A TW200704778A TW 200704778 A TW200704778 A TW 200704778A TW 095111992 A TW095111992 A TW 095111992A TW 95111992 A TW95111992 A TW 95111992A TW 200704778 A TW200704778 A TW 200704778A
- Authority
- TW
- Taiwan
- Prior art keywords
- fluorophore
- chemical entity
- chemical
- fret
- entities
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66842805P | 2005-04-04 | 2005-04-04 | |
US67884205P | 2005-05-06 | 2005-05-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200704778A true TW200704778A (en) | 2007-02-01 |
Family
ID=37073796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095111992A TW200704778A (en) | 2005-04-04 | 2006-04-04 | Screening using polarization anisotropy in fret emissions |
Country Status (5)
Country | Link |
---|---|
US (2) | US20060234279A1 (zh) |
EP (1) | EP1866443A4 (zh) |
JP (1) | JP4921458B2 (zh) |
TW (1) | TW200704778A (zh) |
WO (1) | WO2006107864A1 (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102548466A (zh) * | 2009-07-28 | 2012-07-04 | 霍夫曼-拉罗奇有限公司 | 非侵入性体内光学成像方法 |
TWI808554B (zh) * | 2020-12-04 | 2023-07-11 | 亞光股份有限公司 | 使用陰極發光測量判別半導體材料中的位錯類型和密度的裝置與方法 |
US11782001B2 (en) | 2020-12-04 | 2023-10-10 | Attolight AG | Dislocation type and density discrimination in semiconductor materials using cathodoluminescence measurements |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4921458B2 (ja) * | 2005-04-04 | 2012-04-25 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | Fret発光における偏光異方性を使用したスクリーニングの方法 |
JP5189301B2 (ja) * | 2007-03-12 | 2013-04-24 | オリンパス株式会社 | レーザー走査型顕微鏡 |
RU2513155C2 (ru) | 2008-10-01 | 2014-04-20 | Шервин ХУА | Система и способ стабилизации позвонков при помощи проволочно проводимого транспедикулярного винта |
WO2011123580A1 (en) | 2010-03-30 | 2011-10-06 | Sherwin Hua | Systems and methods for pedicle screw stabilization of spinal vertebrae |
EP2510882B1 (en) | 2009-04-03 | 2017-02-01 | Mitchell A. Hardenbrook | Surgical retractor system |
MX2012011091A (es) | 2010-03-26 | 2013-03-07 | Echostar Technologies Llc | Receptor de television de entrada multiple. |
US8569254B2 (en) | 2010-12-10 | 2013-10-29 | National Yang Ming University | Methods for modulating the expression and aggregation of CAG-expanded gene product in cells and methods for identifying agents useful for doing the same |
EP2683413A1 (en) | 2011-03-07 | 2014-01-15 | F.Hoffmann-La Roche Ag | In vivo selection of therapeutically active antibodies |
WO2012119999A1 (en) | 2011-03-07 | 2012-09-13 | F. Hoffmann-La Roche Ag | Means and methods for in vivo testing of therapeutic antibodies |
KR101158362B1 (ko) * | 2011-04-20 | 2012-06-22 | 한국과학기술원 | 세포 환경 내에서의 단일 분자 수준의 단백질-단백질 상호작용 분석 방법 |
US9746470B2 (en) * | 2011-05-09 | 2017-08-29 | Whitehead Institute For Biomedical Research | Chaperone interaction assays and uses thereof |
JP5877741B2 (ja) * | 2012-03-16 | 2016-03-08 | 株式会社日立製作所 | 細胞数モニタリング方法 |
WO2014059281A1 (en) * | 2012-10-11 | 2014-04-17 | The Regents Of The University Of Michigan | Fluorescence polarization assay for detecting high molecular weight molecules in biological fluids |
CN102967554B (zh) * | 2012-10-29 | 2016-12-21 | 广东工业大学 | 一种双通道、单光路结构的荧光各向异性显微成像装置及方法 |
BR112017015691B1 (pt) * | 2015-01-23 | 2021-06-08 | Bayer Aktiengesellschaft | dispositivo e método para determinar os efeitos dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos |
CN109509509B (zh) * | 2018-09-29 | 2020-12-22 | 江西理工大学 | 基于动态加权蛋白质相互作用网络的蛋白质复合物挖掘方法 |
US11160580B2 (en) | 2019-04-24 | 2021-11-02 | Spine23 Inc. | Systems and methods for pedicle screw stabilization of spinal vertebrae |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5524405A (en) | 1994-02-28 | 1996-06-11 | Byrd; Randall | Wall structure |
US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
US5597696A (en) * | 1994-07-18 | 1997-01-28 | Becton Dickinson And Company | Covalent cyanine dye oligonucleotide conjugates |
US6573045B1 (en) * | 1998-06-05 | 2003-06-03 | Ribotargets, Ltd. | Methods and kits for discovery of RNA-binding compounds |
AU775800B2 (en) * | 1999-06-24 | 2004-08-19 | Christopher V. W. Hogue | Incorporation and applications of biomolecular interactions within a carrier |
US6509161B1 (en) * | 2000-02-29 | 2003-01-21 | Gentronix Limited | Green fluorescent protein |
US6777184B2 (en) * | 2000-05-12 | 2004-08-17 | Caliper Life Sciences, Inc. | Detection of nucleic acid hybridization by fluorescence polarization |
EP1409982A4 (en) * | 2001-06-14 | 2006-05-24 | Anadys Pharmaceuticals Inc | PROCESS FOR SCREENING ON LIGANDS OF TARGET MOLECULES |
US20030228703A1 (en) * | 2002-04-05 | 2003-12-11 | The Regents Of The University Of Michigan | Fluorescence resonance energy transfer quantitation and stoichiometry in living cells |
US20030228603A1 (en) * | 2002-04-05 | 2003-12-11 | Cload Sharon T. | Compositions selective for caffeine or aspartame and methods of using same |
US6713262B2 (en) * | 2002-06-25 | 2004-03-30 | Agilent Technologies, Inc. | Methods and compositions for high throughput identification of protein/nucleic acid binding pairs |
JP2004093527A (ja) * | 2002-09-04 | 2004-03-25 | Center For Advanced Science & Technology Incubation Ltd | 蛍光共鳴エネルギー転移を用いた蛋白質の分析方法 |
JP4214206B2 (ja) * | 2002-12-10 | 2009-01-28 | 独立行政法人理化学研究所 | Fretを利用した蛍光指示薬 |
EP2259050A3 (en) | 2003-08-26 | 2010-12-22 | Blueshift Biotechnologies, Inc. | Time dependent fluorescence measurements |
WO2005081801A2 (en) | 2004-02-09 | 2005-09-09 | Blueshift Biotechnologies, Inc. | Methods and apparatus for scanning small sample volumes |
FR2872287B1 (fr) * | 2004-06-28 | 2007-03-16 | Cis Bio Internat Sa | Procede d'amelioration de la detection des signaux de fluorescence lors d'un transfert d'energie non radiatif |
JP2008505321A (ja) * | 2004-07-02 | 2008-02-21 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | 蛍光体微小環境の探索 |
US8031338B2 (en) * | 2004-12-02 | 2011-10-04 | Vanderbilt University | Measuring Forster resonance energy transfer with polarized and depolarized light |
JP4921458B2 (ja) * | 2005-04-04 | 2012-04-25 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | Fret発光における偏光異方性を使用したスクリーニングの方法 |
JP5189301B2 (ja) * | 2007-03-12 | 2013-04-24 | オリンパス株式会社 | レーザー走査型顕微鏡 |
-
2006
- 2006-04-03 JP JP2008505419A patent/JP4921458B2/ja not_active Expired - Fee Related
- 2006-04-03 WO PCT/US2006/012292 patent/WO2006107864A1/en active Application Filing
- 2006-04-03 EP EP06758259A patent/EP1866443A4/en not_active Withdrawn
- 2006-04-04 US US11/398,496 patent/US20060234279A1/en not_active Abandoned
- 2006-04-04 TW TW095111992A patent/TW200704778A/zh unknown
-
2008
- 2008-02-11 US US12/069,724 patent/US7674588B2/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102548466A (zh) * | 2009-07-28 | 2012-07-04 | 霍夫曼-拉罗奇有限公司 | 非侵入性体内光学成像方法 |
TWI808554B (zh) * | 2020-12-04 | 2023-07-11 | 亞光股份有限公司 | 使用陰極發光測量判別半導體材料中的位錯類型和密度的裝置與方法 |
US11782001B2 (en) | 2020-12-04 | 2023-10-10 | Attolight AG | Dislocation type and density discrimination in semiconductor materials using cathodoluminescence measurements |
Also Published As
Publication number | Publication date |
---|---|
JP4921458B2 (ja) | 2012-04-25 |
US20060234279A1 (en) | 2006-10-19 |
JP2008538004A (ja) | 2008-10-02 |
US7674588B2 (en) | 2010-03-09 |
WO2006107864A1 (en) | 2006-10-12 |
US20080206888A1 (en) | 2008-08-28 |
EP1866443A4 (en) | 2009-04-08 |
EP1866443A1 (en) | 2007-12-19 |
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