TR2023006177A2 - ORAL CARE SOLUTION - Google Patents
ORAL CARE SOLUTIONInfo
- Publication number
- TR2023006177A2 TR2023006177A2 TR2023/006177 TR2023006177A2 TR 2023006177 A2 TR2023006177 A2 TR 2023006177A2 TR 2023/006177 TR2023/006177 TR 2023/006177 TR 2023006177 A2 TR2023006177 A2 TR 2023006177A2
- Authority
- TR
- Turkey
- Prior art keywords
- water
- mouth
- plants
- solution
- drying
- Prior art date
Links
- 239000004615 ingredient Substances 0.000 claims abstract description 8
- 206010052428 Wound Diseases 0.000 claims abstract description 6
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 6
- 206010018276 Gingival bleeding Diseases 0.000 claims abstract description 4
- 208000011759 gum bleeding Diseases 0.000 claims abstract description 4
- 208000004371 toothache Diseases 0.000 claims abstract description 4
- 206010018286 Gingival pain Diseases 0.000 claims abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
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- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 description 26
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 19
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- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 10
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- INVGWHRKADIJHF-UHFFFAOYSA-N Sanguinarin Chemical compound C1=C2OCOC2=CC2=C3[N+](C)=CC4=C(OCO5)C5=CC=C4C3=CC=C21 INVGWHRKADIJHF-UHFFFAOYSA-N 0.000 description 6
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 6
- 206010006326 Breath odour Diseases 0.000 description 5
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- CNBGNNVCVSKAQZ-UHFFFAOYSA-N benzidamine Natural products C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 CNBGNNVCVSKAQZ-UHFFFAOYSA-N 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
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- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 5
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- 208000002399 aphthous stomatitis Diseases 0.000 description 4
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- DTOUUUZOYKYHEP-UHFFFAOYSA-N 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine Chemical compound CCCCC(CC)CN1CN(CC(CC)CCCC)CC(C)(N)C1 DTOUUUZOYKYHEP-UHFFFAOYSA-N 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 3
- FCEXWTOTHXCQCQ-UHFFFAOYSA-N Ethoxydihydrosanguinarine Natural products C12=CC=C3OCOC3=C2C(OCC)N(C)C(C2=C3)=C1C=CC2=CC1=C3OCO1 FCEXWTOTHXCQCQ-UHFFFAOYSA-N 0.000 description 3
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- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 description 3
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- 229940084560 sanguinarine Drugs 0.000 description 3
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- HNNIWKQLJSNAEQ-UHFFFAOYSA-N Benzydamine hydrochloride Chemical compound Cl.C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 HNNIWKQLJSNAEQ-UHFFFAOYSA-N 0.000 description 2
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- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- WEEGYLXZBRQIMU-UHFFFAOYSA-N 1,8-cineole Natural products C1CC2CCC1(C)OC2(C)C WEEGYLXZBRQIMU-UHFFFAOYSA-N 0.000 description 1
- RZYFFJFJWQJRKW-UHFFFAOYSA-L 1-hexadecylpyridin-1-ium;dichloride Chemical compound [Cl-].[Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 RZYFFJFJWQJRKW-UHFFFAOYSA-L 0.000 description 1
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- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
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- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 208000002064 Dental Plaque Diseases 0.000 description 1
- WEEGYLXZBRQIMU-WAAGHKOSSA-N Eucalyptol Chemical compound C1C[C@H]2CC[C@]1(C)OC2(C)C WEEGYLXZBRQIMU-WAAGHKOSSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical group OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 1
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- 244000001385 Sanguinaria canadensis Species 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 102000048514 Stomatin Human genes 0.000 description 1
- 108700037714 Stomatin Proteins 0.000 description 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 description 1
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- 230000001567 anti-fibrinolytic effect Effects 0.000 description 1
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- 230000002882 anti-plaque Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
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- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
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- 230000036765 blood level Effects 0.000 description 1
- 229960001927 cetylpyridinium chloride Drugs 0.000 description 1
- YMKDRGPMQRFJGP-UHFFFAOYSA-M cetylpyridinium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1 YMKDRGPMQRFJGP-UHFFFAOYSA-M 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 description 1
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- FXPVUWKFNGVHIZ-UHFFFAOYSA-L disodium;dodecyl sulfate Chemical compound [Na+].[Na+].CCCCCCCCCCCCOS([O-])(=O)=O.CCCCCCCCCCCCOS([O-])(=O)=O FXPVUWKFNGVHIZ-UHFFFAOYSA-L 0.000 description 1
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- 150000003522 tetracyclines Chemical class 0.000 description 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 description 1
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- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 description 1
- 229960000401 tranexamic acid Drugs 0.000 description 1
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- WGIWBXUNRXCYRA-UHFFFAOYSA-H trizinc;2-hydroxypropane-1,2,3-tricarboxylate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O WGIWBXUNRXCYRA-UHFFFAOYSA-H 0.000 description 1
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Abstract
Buluş kimyasal içermeyen doğal bileşenlerden meydana gelen içeriği ile ağız içinin ferahlığını, dişlerin dayanıklı olmasını sağlayan diş eti kanamalarını durdurucu, diş eti ve diş ağrılarının azaltılmasına yardımcı ve ağız yaralarının iyileşmesini sağlayan diş ve ağız sağlığını koruyucu doğal bir ağız bakım solüsyonudur.The invention is a natural oral care solution that protects dental and oral health, with its content consisting of chemical-free natural ingredients, which ensures the freshness of the mouth, the durability of the teeth, stops gum bleeding, helps reduce gum and tooth pain, and heals mouth wounds.
Description
TARIFNAME AGIZ BAKIMI SOLÜSYONU TEKNIK ALAN Bulus kimyasal içermeyen dogal bilesenlerden meydana gelen içerigi ile agiz içinin ferahligini, dislerin dayanikli olmasini saglayan dis eti kanamalarini durdurucu, dis eti ve dis agrilarinin azaltilmasina yardimci ve agiz yaralarinin iyilesmesini saglayan dis ve agiz sagligini koruyucu dogal bir agiz bakim solüsyonu olup saglik alani ile ilgidir. ÖNCEKI TEKNIK Agiz bakim suyu, (agiz durulama, agiz yakalayicisi, agizdan çalkalama) agizda tutulan veya agiz çevresi ile yikanarak, perioral kaslarin azaltilmasi veya basin hareket ettirilmesiyle olusan sivi bir maddedir. Genellikle agiz gargaralari, agiz boslugundaki mikrobiyal yükü azaltmaya yönelik antiseptik çözeltilerdir, ancak bazi agiz gargaralari, agri kesici, antienflamatuvar veya antifungaller etki gibi baska nedenlerle kullanilmaktadir. Ek olarak, bazi durulamalar, asidi nötralize etmek ve xerostomide (agiz kurulugu) agzi nemli tutmak için kullanilmaktadir. Kozmetik agizliklar, agiz kokusunu geçici olarak kontrol eder ve agizda hos bir tat birakir. DESCRIPTION ORAL CARE SOLUTION TECHNICAL FIELD The invention is effective for the inside of the mouth with its content consisting of natural ingredients that do not contain chemicals. It prevents gum bleeding and provides freshness and durability to the teeth. Helps reduce toothaches and toothaches and improves the healing of mouth wounds. It is a natural oral care solution that protects dental and oral health and provides health It is related to the field. BACKGROUND ART Oral care water, (mouth rinse, mouth catcher, mouth rinse) in the mouth by holding or washing around the mouth, reducing the perioral muscles or pressure It is a liquid substance formed by movement. Usually mouthwashes, mouthwashes They are antiseptic solutions aimed at reducing the microbial load in the cavity, but some Other treatments such as mouthwashes, painkillers, anti-inflammatory or antifungal effects It is used for reasons. Additionally, some rinses help neutralize the acid and It is used to keep the mouth moist in xerostomia (dry mouth). Cosmetic Mouthpieces temporarily control bad breath and leave a pleasant taste in the mouth.
Bir florürlü dis macunu ile firçalandiktan sonra su veya gargara ile durulama, tükürük florid varligini azaltabilir. Bu, anti-kavite yeniden mineralizasyonunu ve florürün antibakteriyel etkilerini azaltabilir. Florürlenmis gargara bu etkiyi hafifletebilir veya yüksek konsantrasyonlarda mevcut florürü artirabilir. Rinsing with water or mouthwash after brushing with a fluoride toothpaste, It may reduce the presence of fluoride in saliva. This promotes anti-cavity remineralization and It may reduce the antibacterial effects of fluoride. Fluoridated mouthwash has this effect. may alleviate or, at high concentrations, increase the amount of fluoride present.
Gargaralarin en yaygin kullanimi evde oral hijyen kurallarinin bir parçasi olarak kullanilan ticari antiseptiklerdir. Ticari gargara firmalarinin örnekleri arasinda Cêpacol, Colgate, Synthol, Corsodyl, Dentyl pH, Listerine, Odol, Oral-B, Sarakan, Scope, Tantum verde, ve Biotene yer almaktadir. The most common use of mouthwashes is as part of oral hygiene at home. commercial antiseptics used. Examples of commercial mouthwash companies include: Cêpacol, Colgate, Synthol, Corsodyl, Dentyl pH, Listerine, Odol, Oral-B, Sarakan, Scope, Tantum verde, and Biotene.
Agiz bakim sularinda yer alan malzemeler Listerine Alkol, bakterileri yok etmek için agiz gargarasina eklenir, ancak plakayi delmeye yardimci olan mentol, okaliptol ve timol gibi temel aktif maddeler için birtasiyici ajan olarak hareket eder. Bazen lezzet verici için tasiyici olarak önemli miktarda alkol (% 27'ye varan vol) eklenir. Alkol içeriginden ötürü, durulamadan sonra, nefes alkol seviyelerinin 10 dakika sonra normale dönmesine ragmen, bir alkol testinin basarisiz olmasi mümkündür. Ek olarak, alkol agizda bakteriyel aktiviteyi tesvik eden, daha kötü kokulu uçucu sülfür bilesikleri birakan bir kurutma ajanidir. Ingredients in mouth care waters listerine Alcohol is added to mouthwash to destroy bacteria, but does not cause plaque buildup. A carrier agent for key active ingredients such as menthol, eucalyptol and thymol, which help acts as. Sometimes a significant amount of alcohol (%) is used as a carrier for the flavoring. Up to 27 vols) are added. Due to its alcohol content, after rinsing, breath alcohol Although blood levels return to normal after 10 minutes, an alcohol test It is possible that it will fail. Additionally, alcohol promotes bacterial activity in the mouth. It is a drying agent that leaves more foul-smelling volatile sulfur compounds.
Heksetidin (Stomatin) Heksetidin (Stomatidin) genis bir antibakteriyel ve antifungal etkiye sahiptir. 100 mg/ml'lik bir konsantrasyonda ilaç çogu bakteriyi baskilamaktadir. Ilacin antimikrobiyal etkisi, bakteriyel metabolizmanin (tiyamin antagonisti) oksidatif reaksiyonlarinin bastirilmasi ile iliskilidir. Mukoza zarinda anestezik etkisi vardir. Hexetidine (Stomatin) Hexetidine (Stomatidine) has a broad antibacterial and antifungal effect. one hundred At a concentration of mg/ml the drug suppresses most bacteria. your medicine antimicrobial effect, oxidative effect of bacterial metabolism (thiamine antagonist) It is associated with the suppression of reactions. It has an anesthetic effect on the mucous membrane.
Heksetidin, mukoza zarina çok iyi yapisir ve pratik olarak emilmez. Aktif maddenin tek bir uygulamasindan sonra, izleri 65 saat boyunca gingival mukoza üzerinde bulunur. Dislerdeki plaklarda aktif konsantrasyonlar, uygulamadan 10 ila 14 saat sonra devam eder. Hexetidine adheres very well to the mucous membrane and is practically not absorbed. active ingredient After a single application, scars remain on the gingival mucosa for 65 hours. is available. Active concentrations in dental plaque persist 10 to 14 hours after application. then continues.
Benzidamin (Difflam) Agiz boslugundaki agri için, örnegin, aftöz stomatitis ile bilesimdeki analjeziklerle çalkalama maddeleri (örnegin, benzidamin veya "Diflam"), genellikle yemeklerden önce yemek sirasinda rahatsizligi hafifletmek için agriyi hafifletmeye yardimci olur. Benzydamine (Difflam) For pain in the oral cavity, for example, with aphthous stomatitis, with analgesics in the composition rinses (e.g. benzydamine or "Diflam"), usually after meals It helps relieve pain before eating to relieve discomfort during meals.
Betametazon Betametazon bazen kortikosteroid ilaçlar içerigi olan bir anti-inflamatuar ilaç olarak kullanilir. Agiz mukozasinin, örnegin aftöz stomatitin ciddi inflamasyonu için endikedir. Betamethasone Betamethasone is sometimes used as an anti-inflammatory drug containing corticosteroid drugs. is used. For severe inflammation of the oral mucosa, e.g. aphthous stomatitis is indicated.
Setilpiridinyum klorür Agiz çalkalamalarinda setilpiridinyum klorür (ör. % 0.05) agiz kokusu (agizdan kötü nefes) tedavisi için özel durulamalarda kullanilir. Setilpiridinyum klorürlü agiz gargarasi kloheksidin'den daha az etkiye sahiptir ve dislerin mine, bazen de yanma hissi veya ülser görünümünde lekelere neden olabilir. Cetylpyridinium chloride Cetylpyridinium chloride (e.g. 0.05%) in mouth rinses for bad breath (bad breath) It is used in special rinses for the treatment of breathing. Mouth with cetylpyridinium chloride gargle is less effective than chlohexidine and can cause damage to the enamel of the teeth, sometimes causing burning. It may cause spots that feel or look like ulcers.
Uçucu Yaglar Uçucu yaglar bitki materyallerinden izole edilmis yaglardir. Uçucu yaglara dayanan çalkalayicilar plak elimine edilmesinde ve dis eti iltihabinin önlenmesinde geleneksel çalkalayicilardan daha etkili olabilirler. Çürük gelisme riski olan kisiler için floridli agiz gargaralari önerilir. Florür dis minesini güçlendirir ve dis çürügünü önler. Dis macunlarinda etkili florür konsantrasyonu % 0.10'dan (1000 ppm) az degildir. Bu seviyenin altinda, dis macunlarinin çürüge karsi mücadelede etkinligi kanitlanmamistir. Essential Oils Essential oils are oils isolated from plant materials. Based on essential oils shakers help eliminate plaque and prevent gingivitis They may be more effective than traditional shakers. Fluoride mouthwashes are recommended for people at risk of developing cavities. fluoride dis It strengthens enamel and prevents tooth decay. Effective fluoride in toothpastes Its concentration is not less than 0.10% (1000 ppm). Below this level, external The effectiveness of their pastes in the fight against caries has not been proven.
Ingiliz Dis hekimligi Birligi, florifiye dis macunlariyla dis firçalamaya ek olarak florifiye durulama maddelerinin kullanilmasini önermektedir. Popüler çalkalama maddelerinde sodyum florür konsantrasyonu 100 ppm ila 225 ppm arasinda degismektedir. Ingiliz dis hekimlerinin gözlemlerine göre, çogu insan dislerini firça ve dis macunu ile firçaladiktan sonra agizlarini suyla durulamaktadir. Bu, dislerin emayesindeki florür konsantrasyonunu azaltmaktadir. 100 ppm'lik bir florür içerigine sahip çalkalayicilarin kullanilmasi, su ile durulamadan önce flor konsantrasyonunu geri kazandirir. 225 ppm'lik bir florür içerigine sahip çalkalayicilarin kullanimi, tek basina dis macununa kiyasla daha yüksek bir koruma seviyesi saglar. Arastirmaya dayanarak, Ingiliz dis hekimleri dis minesinin dekalsifikasyonunu önlemek için florür içeren bir durulama yardimi ile günde iki kez agiz yikamasini tavsiye etmektedir. The British Dental Association recommends that in addition to brushing with fluoridated toothpaste recommends the use of fluoridated rinse agents. Popular shaking Sodium fluoride concentration in substances between 100 ppm and 225 ppm It is changing. According to the observations of British dentists, most people brush their teeth. and rinse their mouths with water after brushing with toothpaste. This is your teeth It reduces the fluoride concentration in the enamel. Using shakers with a fluoride content of 100 ppm, water Restores fluoride concentration before rinsing. a fluoride of 225 ppm The use of shakers containing ingredients is more effective than toothpaste alone. Provides a high level of protection. Based on research, British dentists with the aid of a rinse containing fluoride to prevent decalcification of the enamel. He recommends washing his mouth twice a day.
Hidrojen Peroksit Agiz çalkalamadaki hidrojen peroksit bir oksitleyici olarak kullanilabilir (örnegin Peroksil, % 1.5). Anaerobik bakterileri öldürür ve köpürmeye basladiginda mekanik bir temizleme etkisine sahiptir, çünkü agizda yabanci cisimlerle temas eder. Uzun süreli kullanimda, dilin papillalarinin hipertrofisi gibi yan etkiler olusabilir. Hydrogen peroxide Hydrogen peroxide in mouthwash can be used as an oxidizer (e.g. peroxyl, 1.5%). It kills anaerobic bacteria and when it starts to foam, mechanical It has a cleaning effect because it comes into contact with foreign objects in the mouth. LONG With prolonged use, side effects such as hypertrophy of the papillae of the tongue may occur.
Fenoller Fenoller ile agiz için çalkalayicilar (örnegin, Listerin) karsi-aktif bir etkiye sahiptir, ancak klorheksidin'den daha az etkilidir. Fenoller dis minesini leke etmez. phenols Oral rinses with phenols (for example, Listerine) have a counteractive effect, however, it is less effective than chlorhexidine. Phenols do not stain tooth enamel.
Sanguinarin Sanguinarin içeren agiz gargaralari, plak ve kötü nefesi ortadan kaldiran preparatlar olarak pazarlanmaktadir. Bu, alkaloidlerin çikarilmasinin sonucu olan zehirli bir bitkisel özdür. Sanguinaria Canadensis, Argemone Mexicana (argonum Meksika) ve digerleri gibi bitkilerden elde edilir. Bununla birlikte, kullanimi genellikle yanaklarin mukoz membraninda lökoplaki (agizda beyaz bir nokta) gelismesi ile iliskilidir. Bu tür bir lökoplaki, "sanguinarine ile iliskili keratoz" olarak adlandirilir. sanguinarine Mouthwashes containing sanguinarine eliminate plaque and bad breath They are marketed as preparations. This is the result of the removal of alkaloids. It is a poisonous herbal extract. Sanguinaria Canadensis, Argemone Mexicana (argonum It is obtained from plants such as Mexico) and others. However, its use is generally with the development of leukoplakia (a white spot in the mouth) on the mucous membrane of the cheeks It is related. This type of leukoplakia is called "sanguinarine-associated keratosis."
Bukkal kavitede lökoplaki olanlarin % 80'den fazlasi bu maddeyi kullanmaktadir. Bu maddeyi kullanmayi biraktiktan sonra bile, lezyon kisiyi birkaç yil daha rahatsiz Sodyum bikarbonat (kabartma tozu) Bazen sodyum bikarbonat, çesitli semptomlari ortadan kaldirmak için bir ev agzi ile durulama solüsyonu elde etmek üzere tuz ile karistirilir. Eczacilar, eger gerekliyse, temel katki maddelerinden kolayca hazirlanabilirlerse de, % 1 sodyum bikarbonat ve % 1.5 sodyum klorürün hazir sulu çözeltilerini de satmaktadir. Bazen sodyum bikarbonat bazli agiz gargarasi, viskoz tükürügü uzaklastirmak ve agiz boslugunun dokularini daha iyi görsellestirmek için kullanilir. More than 80% of those with leukoplakia in the buccal cavity use this substance. This Even after stopping using the substance, the lesion may continue to bother the person for several years. Sodium bicarbonate (baking soda) Sometimes sodium bicarbonate is used as a home remedy to eliminate various symptoms. It is mixed with salt to obtain a rinsing solution. Pharmacists, if necessary Although they can be easily prepared from basic ingredients, 1% sodium bicarbonate and ready-made aqueous solutions of 1.5% sodium chloride. sometimes sodium bicarbonate-based mouthwash to remove viscous saliva and cleanse the oral cavity It is used to better visualize textures.
Sodyum klorür Agiz boslugu için sicak tuz banyolari (durulama) genellikle dental cerrahi girisimlerden sonra kullanilir, böylece yiyecegin geri kalani yaralarin iyilesmesine engel olmaz ve enfeksiyonlarin gelismesini önler. Bazi cerrahlar hala ameliyattan sonra yaralari temizlemenin ana yolu olarak tuzlu su ile durulamayi düsünmektedir. Sodium chloride Warm salt baths (rinses) for the oral cavity are often used in dental surgery It is used after interventions so that the rest of the food helps the wounds heal. It does not interfere and prevents the development of infections. Some surgeons still avoid surgery He then considers rinsing with salt water the main way to clean the wounds.
Dis çikarirken, sicak tuzlu su ile durulama, çikarildiktan 24 saat sonra baslatilmalidir. When teething, rinse with warm salt water, 24 hours after teething should be started.
Sodyum lauril sülfat Sodyum lauryl sülfatin (LSM) rekürren aftöz stomatit hastaligina yatkin kisilerde aftöz stomatitin gelismesine neden oldugu bilinmektedir. Madde, durulama dahil olmak üzere agiz hijyeni için birçok ürünün bilesiminde bulunur. Bununla birlikte, birçok popüler ürünler ayrica sodyum lauril sülfat (örn. Listerin) içerir. sodium lauryl sulfate Sodium lauryl sulfate (LSM) in people prone to recurrent aphthous stomatitis It is known to cause the development of aphthous stomatitis. substance, rinse included It is found in many products for oral hygiene, including: With this, Many popular products also contain sodium lauryl sulfate (e.g. Listerine).
Tetrasiklin Tetrasiklin, bazen bir agzi yetiskinlerle yikamak için kullanilabilen bir antibiyotiktir (çocuklarda mine renginin kirmizi olmasina neden olur). Bazen tetrasiklin herpetiformis ülserler kullanilir, ancak uzun süreli kullanimi bakterilerin gerekli sayida yoklugunda agiz boslugu içinde mantar olacak asiri büyümeye açabilir. tetracycline Tetracycline is an antibiotic that can sometimes be used to rinse a mouth with adults (causes red enamel color in children). Sometimes tetracycline herpetiformis ulcers, but long-term use is necessary for bacteria Their absence may lead to excessive growth of fungi within the oral cavity.
Traneksamik asit inceltme) antikoagülan alinmasi sirasinda veya koagülopati olan kisilerde dis operasyonlarindan sonra kanamanin önlenmesi için bir anti-fibrinolitik durulama olarak kullanilir. Tranexamic acid thinning) while taking anticoagulants or in people with coagulopathy an anti-fibrinolytic rinse to prevent bleeding after surgery It is used as.
Triklosan Triklosan, bisfenol ve noniyonik yüzey aktif maddelerden olusan bir antiseptiktir. triclosan It is an antiseptic consisting of triclosan, bisphenol and nonionic surfactants.
Orta derecede sabitlik, genis bir antibakteriyel etkiye sahiptir ve özellikle kopolimerleri veya çinko sitrat ile birlikte, önemli bir antimikrobiyal ve plak önleyici bir etki saglamaktadir. Triklosan mine boyamasina neden olmaz. Ancak triklosanin güvenligi söz konusudur. 2010'dan beri, gida ile dogrudan temas halinde olan gida ve antiseptik kullanimi tüm Avrupa'da yasaklanmistir. It has moderate stability, a broad antibacterial effect and is particularly together with its copolymers or zinc citrate, is an important antimicrobial and antiplaque agent. provides an effect. Triclosan does not cause enamel staining. But triclosanin security is in question. Since 2010, food in direct contact with food and the use of antiseptics is banned throughout Europe.
Florür zararlari konusunda uzmanlarin oldukça fazla tespiti bulunmaktadir. Her ne kadar dogal bir bilesen olsa da bu maddeye fazla maruz kalmak bir dizi saglik sorununu beraberinde getirir. Belli bir miktar üzerindeki florür kullanimi özellikle çocuklar için tavsiye edilmemektedir. Çocukluk döneminde, disler gelisirken yüksek konsantrasyonlarda florür maruziyeti, dis florozuna neden olur. Bununla beraber dis minesinde küçük beyaz çizgiler veya lekeler olusur. Bu yüzden 6 yasindan küçük çocuklarin florür içeren bir gargara kullanmasi tavsiye edilmez. Yetiskinler kadar çocuklarin da dogal agiz bakim solüsyonu kullanmalari oldukça önemlidir. Nörolojik ve tiroid problemlerine de sebep oldugu ifade edilen florür; akne ve diger cilt sorunlarini da beraberinde getirebilmektedir. Önceki teknikte yer alan agiz bakim solüsyonlarinin zararlari sunlardir: - Kimyasal içerikli olup, agizda acimtirak bir tat birakmalari, Dislerin parlakligini alarak dislerin mine tabakasinin asinmasina neden olmalari, - Dislerde sararmalar ve çürümelere sebep olmalari, - Yutma durumlarinda mide bulantilari, mide rahatsizliklarina sebep olmalari, - Rahatsiz edici bir sekilde agiz ve dil çevresini yakan kimyasal bilesenler içermeleri, - Çocuklarin kullanimina uygun olmamalari, - Agizda olusan aflarin giderimine katki sunmamasi, - Florür kaynakli ve diger kimyasallarin agiz bakimi esnasinda yutulmasi vücutta birikme ile zeka geriligi, Alzheimer riski barindirmasi, - Çocuklar, yaslilar, engelli bireylerin kullanimina hitap etmemesi, - Dis eti hassasiyeti olan ve dislerinde çekilmeleri olan kisileri rahatsiz etmeleri ve kimyasallarin tahris etmesi gibi bir çok zararlari bulunmaktadir. There are many findings by experts regarding the harmful effects of fluoride. Whatever Although it is such a natural ingredient, excessive exposure to this substance can cause a number of health problems. brings with it the problem. Fluoride use above a certain amount is especially It is not recommended for children. During childhood, when teeth are developing, high Exposure to high concentrations of fluoride causes dental fluorosis. However, dis Small white lines or spots appear on the enamel. That's why he's under 6 years old It is not recommended for children to use a mouthwash containing fluoride. up to adults It is very important for children to use natural oral care solutions. Neurological and fluoride, which is said to cause thyroid problems; acne and other skin It may also cause problems. The harms of the oral care solutions used in the previous technique are as follows: - They contain chemicals and leave a bitter taste in the mouth, It causes wear of the enamel layer of the teeth by removing the shine of the teeth. to be, - Causes yellowing and decay in teeth, - They cause nausea and stomach discomfort when swallowing, - Chemical compounds that cause discomfort around the mouth and tongue they contain, - They are not suitable for use by children, - It does not contribute to the removal of mouth sores, - Ingestion of fluoride-based and other chemicals during oral care Accumulation in the body causes mental retardation, Alzheimer's risk, - It is not suitable for use by children, elderly people and disabled individuals, - They do not disturb people with gum sensitivity and receding teeth. It has many harmful effects such as irritation and chemical irritation.
BULUSUN AÇIKLAMASI Bulus konusu agiz bakim solüsyonu dogal içerikli olup; - Dis eti kanama durdurucu - Florür içermemesi sayesinde dis çatlaklarinin olusumunu engellemesi, - Dogal içerige sahip olmasi, - Agiz yaralarina iyilestirmesi, - Bagisiklik sistemini kuvvetlendirmesi, - Dis eti hassasiyeti olanlarin kullanima uygun olmasi, - Çocuklardan, yaslilara, engelliler içinde uygun bir formülasyon olmasi, - Maliyetinin düsük olmasi, - Dislere beyazlik saglamasi, - Ferah bir agiz bakimi saglamasi, - Agiz bakimina uygun olmasi, - Kimyasal içermemesi sebebiyle dis ömrünün uzatilmasi, - Agizda istenmeyen tat birakmamasi, - Yutma sebebi ile vücutta birikmeme ve idrarla kolaylikla atilmasi, - Zeka geriligi ve Alzheimer riski barindirmamasi, - Agiz ve bogaz agrilarina iyi gelmesi böylelikle soguk alginliginda da fayda saglayabilmesi, - Agiz boslugundaki mikrobiyal yükü azaltmaya yönelik antiseptik çözeltilere sahip olmasi, - Agri kesici, antienflamatuvar veya antifungaller etkileri bulunmasi, - Asidi nötralize etme ve xerostomide (agiz kurulugu) agzi nemli tutmak için tükürük olarak hareket etmeyi saglayan dogal bir bilesenden meydana gelmesi gibi avantajlara sahiptir. DESCRIPTION OF THE INVENTION The oral care solution of the invention contains natural ingredients; - Gum bleeding stopper - It prevents the formation of tooth cracks because it does not contain fluoride, - It has natural content, - Heals mouth wounds, - Strengthens the immune system, - Suitable for use by those with gum sensitivity, - It is a suitable formulation for children, elderly and disabled people, - Low cost, - Provides whiteness to teeth, - Provides a refreshing oral care, - It is suitable for oral care, - Extending the life of the tooth because it does not contain chemicals, - Does not leave an unpleasant taste in the mouth, - It does not accumulate in the body due to swallowing and is easily excreted with urine, - No risk of mental retardation and Alzheimer's, - It is good for mouth and throat pains, thus it is also beneficial for colds. can provide, - Antiseptic solutions to reduce the microbial load in the oral cavity to have, - Having pain relieving, anti-inflammatory or antifungal effects, - To neutralize acid and keep the mouth moist in xerostomia (dry mouth) As it consists of a natural component that allows it to act as saliva It has advantages.
Sekillerin Açiklamasi Sekil 1. Agiz bakimi solüsyonu üretim adimlari sematik görünümü Referans Listesi Yikama Temizleme Kurutma 40 Ögütme/toz haline getirme 50 Karistirma 60 Çözeltiye ekleme 70 Liyofilizasyon ve toz haline getirme 80 Nanopartikül üretimi 90 Karisimin saglanmasi BU LUSUN DETAYLI AÇIKLAMASI Menengiç, karadut ve turnefor dagdagani otunun saf suda yikanip durulanmasi, Menengiç, karadut ve turnefor dagdagani otunun Sodyum hidroksit (NaOH) da bir gece bekletilerek yaglarinin ve kirliliklerin giderimi, Menengiç, karadut ve turnefor dagdagani otunun dondurulduktan sonra Kurutulan otlarin seramik havan ve akabinde mikserde 15 dakika ögütülerek toz haline getirilmesi, miligram turnefor dagdagani otu tozunun 1-1.5 saat kadar 2.55-7.75 ml ozonlanmis suya yedirilmesi, Olusan karisima 15-55 ml Yalanci brom suyu ilave edilmesi, Bitkilerin toplanip ve yikanmasi, Sodyum hidroksit (NaOH) da bir gece bekletilerek yaglarinin ve kirliliklerin giderimi, Vakum etüvünde bir gece kurutulduktan sonra ayri ayri beherlere alinan tüm bitkilerin buzdolabinda 2 gün dondurulmasi, Dondurulan numunelerin Iiyofilizatör (dondurarak kurutma) cihazinda 4 gün kurutulmasi, Kurutulan bitkilerin seramik havanda toz haline getirilmesi, Tablo 1 de yer alan oranlarda tozlar elektrohidrodinamik atomizasyon teknigi ile %7 kitosan (KTS) biyopolimer-% çapraz baglayici içeren sistemde kapsüllenerek çekirdek kabuk etkilesimine sahip nanopartiküller haline getirilmesi, Elde edilen nanopartiküller 175 mg-250 mg oraninda yalanci brom suyu- menengiç, karadut ve turnefor dagdagani-ozonlanmis su karisimina takviye edilerek bir gün karistirilmasi, o Karisimin bir kaba konulmasi islem adimlarini içermektedir. Explanation of Figures Figure 1. Schematic view of oral care solution production steps Referance list Washing Cleaning Drying 40 Grinding/pulverizing 50 Mixing 60 Adding to the solution 70 Lyophilization and trituration 80 Nanoparticle production 90 Ensuring mixing DETAILED EXPLANATION OF THIS ISSUE Wash terebinth, black mulberry and tournephor dagdagani herb in pure water and rinsing, Sodium hydroxide (NaOH) of terebinth, black mulberry and tournephor dagdagani herb It is kept overnight to remove oils and impurities, Terebinth, black mulberry and turnefor dagdagani herb after freezing The dried herbs were ground in a ceramic mortar and then in a mixer for 15 minutes. pulverization, 2.55-7.75 ml of milligram turnefor dagdagani herb powder for 1-1.5 hours Feeding it into ozonated water, Adding 15-55 ml of False bromine water to the resulting mixture, Collecting and washing plants, By keeping it in sodium hydroxide (NaOH) overnight, the oils and impurities are removed. removal, After drying in a vacuum oven overnight, all the samples were taken into separate beakers. freezing the plants in the refrigerator for 2 days, The frozen samples were kept in the lyophilizer (freeze drying) device for 4 days. drying, Grinding the dried plants into powder in a ceramic mortar, Powders in the proportions in Table 1 were prepared by electrohydrodynamic atomization technique. with 7% chitosan (KTS) biopolymer-% crosslinker It has a core-shell interaction by being encapsulated in a system containing turning into nanoparticles, The resulting nanoparticles contain 175 mg-250 mg of pseudo-bromine water. terebinth, black mulberry and turnefor dagdagani-supplement the ozonated water mixture and mixing for a day, o It includes the process steps of placing the mixture into a container.
Tablo 1. Nanopartikül üretiminde kullanilan malzemeler ve turnefor dagdagani- ozonlanmis su -35 mI yalanci brom suyu Table 1. Materials used in nanoparticle production and turnefor dagdagani- ozonated water -35 ml pseudo bromine water
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