TR200102306T2 - Faktör Xa önleyici olarak heterosiklik türevler. - Google Patents
Faktör Xa önleyici olarak heterosiklik türevler.Info
- Publication number
- TR200102306T2 TR200102306T2 TR2001/02306T TR200102306T TR200102306T2 TR 200102306 T2 TR200102306 T2 TR 200102306T2 TR 2001/02306 T TR2001/02306 T TR 2001/02306T TR 200102306 T TR200102306 T TR 200102306T TR 200102306 T2 TR200102306 T2 TR 200102306T2
- Authority
- TR
- Turkey
- Prior art keywords
- heterocyclic derivatives
- inhibitor
- factor
- thrombotic
- relates
- Prior art date
Links
- 125000000623 heterocyclic group Chemical group 0.000 title abstract 3
- 229940123583 Factor Xa inhibitor Drugs 0.000 title 1
- 230000002429 anti-coagulating effect Effects 0.000 abstract 2
- 230000002785 anti-thrombosis Effects 0.000 abstract 2
- 239000003146 anticoagulant agent Substances 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
Söz konusu bulus formül I'e uygun heterosiklik türevler ya da bunlarin farmasötik olarak kabul edilir tuzlari ile ilgili olup, anti-trombotik ve anti-koagülan hususiyetlere sahip ve insanlarin ve hayvanlarin tedavi edilme yöntemlerinde faydalidir. Bulus ayrica heterosiklik türevleri ihtiva eden farmasötik bilesimlerin hazirlanmasi ve bunlarin anti-trombotik ve anti-koagülan bir etkiye sahip ilaçlarin imalatinda kullanilmasi ile de ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9902989.4A GB9902989D0 (en) | 1999-02-11 | 1999-02-11 | Heterocyclic derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200102306T2 true TR200102306T2 (tr) | 2001-12-21 |
Family
ID=10847476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/02306T TR200102306T2 (tr) | 1999-02-11 | 2000-02-08 | Faktör Xa önleyici olarak heterosiklik türevler. |
Country Status (24)
Country | Link |
---|---|
US (1) | US6723723B1 (tr) |
EP (1) | EP1150974B1 (tr) |
JP (1) | JP2002536443A (tr) |
KR (1) | KR20010102072A (tr) |
AT (1) | ATE223402T1 (tr) |
AU (1) | AU757738B2 (tr) |
BR (1) | BR0008130A (tr) |
CA (1) | CA2362392A1 (tr) |
CZ (1) | CZ20012867A3 (tr) |
DE (1) | DE60000410T2 (tr) |
DK (1) | DK1150974T3 (tr) |
ES (1) | ES2181637T3 (tr) |
GB (1) | GB9902989D0 (tr) |
HU (1) | HUP0105102A3 (tr) |
IL (1) | IL144792A0 (tr) |
NO (1) | NO20013921L (tr) |
NZ (1) | NZ513350A (tr) |
PL (1) | PL349220A1 (tr) |
PT (1) | PT1150974E (tr) |
RU (1) | RU2226193C2 (tr) |
SK (1) | SK11462001A3 (tr) |
TR (1) | TR200102306T2 (tr) |
WO (1) | WO2000047573A1 (tr) |
ZA (1) | ZA200106337B (tr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
TWI290136B (en) | 2000-04-05 | 2007-11-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
WO2003000657A1 (fr) | 2001-06-20 | 2003-01-03 | Daiichi Pharmaceutical Co., Ltd. | Derives de diamine |
JP4744149B2 (ja) | 2002-12-03 | 2011-08-10 | ファーマサイクリックス インコーポレイテッド | 第viia因子阻害剤としての2−(2−ヒドロキシビフェニル−3−イル)−1h−ベンゾイミダゾール−5−カルボキサミジン誘導体 |
WO2006109817A1 (ja) * | 2005-04-06 | 2006-10-19 | Banyu Pharmaceutical Co., Ltd. | 1,4-置換ピペラジン誘導体 |
JP5214096B2 (ja) * | 2005-06-17 | 2013-06-19 | 富士フイルムファインケミカルズ株式会社 | 新規なビピリジン誘導体 |
BR112021026410A2 (pt) | 2019-07-01 | 2022-02-08 | Tonix Pharma Ltd | Anticorpos anti-cd154 e usos dos mesmos |
CN116963750A (zh) | 2021-01-06 | 2023-10-27 | 通尼克斯制药有限公司 | 用经修饰的抗-cd154抗体诱导免疫耐受的方法 |
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US4167567A (en) | 1978-05-05 | 1979-09-11 | The Upjohn Company | Antihypertensive 4-aminoquinolines |
US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
SE8203887D0 (sv) | 1982-06-23 | 1982-06-23 | Kabivitrum Ab | Nya trombininhiberande foreningar |
DE3246932A1 (de) | 1982-12-16 | 1984-06-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte 5h-pyrimido(5,4-b)indole |
FR2557570B1 (fr) | 1984-01-04 | 1986-04-18 | Adir | Nouveaux derives de la quinoleine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
US4840963A (en) | 1984-03-14 | 1989-06-20 | Merck & Co., Inc. | 2-Sulfamoyl-1H-indole derivatives for the treatment of elevated intraocular pressure |
GB8601160D0 (en) | 1986-01-17 | 1986-02-19 | Fujisawa Pharmaceutical Co | Heterocyclic compounds |
GB8603120D0 (en) | 1986-02-07 | 1986-03-12 | Pfizer Ltd | Anti-dysrhythmia agents |
GB8609630D0 (en) | 1986-04-19 | 1986-05-21 | Pfizer Ltd | Anti-arrhythmia agents |
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DE3905364A1 (de) | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
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UA56197C2 (uk) * | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
WO1998035956A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
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GB9715894D0 (en) * | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic derivatives |
GB9715892D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
GB9809349D0 (en) | 1998-05-02 | 1998-07-01 | Zeneca Ltd | Heterocyclic derivatives |
KR20010043246A (ko) | 1998-05-02 | 2001-05-25 | 다비드 에 질레스 | Xa 인자를 억제시키는 헤테로시클릭 유도체 |
-
1999
- 1999-02-11 GB GBGB9902989.4A patent/GB9902989D0/en not_active Ceased
-
2000
- 2000-02-08 ES ES00902725T patent/ES2181637T3/es not_active Expired - Lifetime
- 2000-02-08 AU AU24470/00A patent/AU757738B2/en not_active Ceased
- 2000-02-08 EP EP00902725A patent/EP1150974B1/en not_active Expired - Lifetime
- 2000-02-08 PT PT00902725T patent/PT1150974E/pt unknown
- 2000-02-08 BR BR0008130-2A patent/BR0008130A/pt not_active IP Right Cessation
- 2000-02-08 TR TR2001/02306T patent/TR200102306T2/tr unknown
- 2000-02-08 NZ NZ513350A patent/NZ513350A/xx unknown
- 2000-02-08 RU RU2001124855/04A patent/RU2226193C2/ru not_active IP Right Cessation
- 2000-02-08 DE DE60000410T patent/DE60000410T2/de not_active Expired - Lifetime
- 2000-02-08 PL PL00349220A patent/PL349220A1/xx not_active Application Discontinuation
- 2000-02-08 HU HU0105102A patent/HUP0105102A3/hu unknown
- 2000-02-08 DK DK00902725T patent/DK1150974T3/da active
- 2000-02-08 US US09/913,071 patent/US6723723B1/en not_active Expired - Fee Related
- 2000-02-08 SK SK1146-2001A patent/SK11462001A3/sk unknown
- 2000-02-08 KR KR1020017010184A patent/KR20010102072A/ko not_active Application Discontinuation
- 2000-02-08 WO PCT/GB2000/000354 patent/WO2000047573A1/en not_active Application Discontinuation
- 2000-02-08 IL IL14479200A patent/IL144792A0/xx unknown
- 2000-02-08 JP JP2000598493A patent/JP2002536443A/ja active Pending
- 2000-02-08 CZ CZ20012867A patent/CZ20012867A3/cs unknown
- 2000-02-08 CA CA002362392A patent/CA2362392A1/en not_active Abandoned
- 2000-02-08 AT AT00902725T patent/ATE223402T1/de active
-
2001
- 2001-08-01 ZA ZA200106337A patent/ZA200106337B/en unknown
- 2001-08-10 NO NO20013921A patent/NO20013921L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1150974B1 (en) | 2002-09-04 |
US6723723B1 (en) | 2004-04-20 |
ATE223402T1 (de) | 2002-09-15 |
JP2002536443A (ja) | 2002-10-29 |
DE60000410D1 (de) | 2002-10-10 |
CZ20012867A3 (cs) | 2001-10-17 |
CA2362392A1 (en) | 2000-08-17 |
AU757738B2 (en) | 2003-03-06 |
PL349220A1 (en) | 2002-07-01 |
AU2447000A (en) | 2000-08-29 |
NZ513350A (en) | 2003-01-31 |
GB9902989D0 (en) | 1999-03-31 |
PT1150974E (pt) | 2003-01-31 |
BR0008130A (pt) | 2002-02-05 |
HUP0105102A2 (hu) | 2002-05-29 |
DE60000410T2 (de) | 2003-06-05 |
NO20013921L (no) | 2001-10-10 |
KR20010102072A (ko) | 2001-11-15 |
HUP0105102A3 (en) | 2003-01-28 |
IL144792A0 (en) | 2002-06-30 |
NO20013921D0 (no) | 2001-08-10 |
SK11462001A3 (sk) | 2001-12-03 |
DK1150974T3 (da) | 2002-12-02 |
RU2226193C2 (ru) | 2004-03-27 |
WO2000047573A1 (en) | 2000-08-17 |
EP1150974A1 (en) | 2001-11-07 |
ZA200106337B (en) | 2002-11-01 |
ES2181637T3 (es) | 2003-03-01 |
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