TR200101750T2 - KQT1 kanalı inhibitörlerinin bir ilacın üretiminde kullanımı. - Google Patents

KQT1 kanalı inhibitörlerinin bir ilacın üretiminde kullanımı.

Info

Publication number
TR200101750T2
TR200101750T2 TR2001/01750T TR200101750T TR200101750T2 TR 200101750 T2 TR200101750 T2 TR 200101750T2 TR 2001/01750 T TR2001/01750 T TR 2001/01750T TR 200101750 T TR200101750 T TR 200101750T TR 200101750 T2 TR200101750 T2 TR 200101750T2
Authority
TR
Turkey
Prior art keywords
kqt1
drug
production
helminths
ectoparasites
Prior art date
Application number
TR2001/01750T
Other languages
English (en)
Inventor
Gerlach Uwe
Hofmann Joachim
Jochen Lang Hans
Wei Aguan
Original Assignee
Aventis Pharma Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh
Publication of TR200101750T2 publication Critical patent/TR200101750T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

KQT1-kanalinin inhibitörleri helmintler ve ektoparazitler için yeni ölümcül bir neden olusturmaktadir. Bu itibarla helmintler ve ektoparazitlerde ortaya çikan selüler KQT1 kanalinin bloke edicileri, helmintler ya da ektoparazitlerin istilasina ugramis olan omurgali hayvanlarin ve insanlarin tedavisi için bir ilacin üretiminde kullanilmaktadir. Sözü edilen KQT1 bloke ediciler tek basina ya da baska ilaç maddeleri ile kombinasyon halinde ve terapötik uygulamalar içinde kullanilmaktadir. KQT1 kanalinin inhibitörleri ayni sekilde hasereler, örümcekgiller, yumusakçalar ve nematodlar gibi bitkilere zarar veren hayvanlar için yeni bir etki mekanizmasi olusturmakta ve bunun sonucunda bir bitki koruma maddesinin üretimi için kullanilmaktadir.
TR2001/01750T 1998-12-17 1999-12-07 KQT1 kanalı inhibitörlerinin bir ilacın üretiminde kullanımı. TR200101750T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19858253A DE19858253A1 (de) 1998-12-17 1998-12-17 Verwendung von Inhibitoren des KQt1-Kanals zur Herstellung eines Medikaments zur Behandlung von Krankheiten, die durch Helminthen und Ektoparasiten hervorgerufen werden

Publications (1)

Publication Number Publication Date
TR200101750T2 true TR200101750T2 (tr) 2002-01-21

Family

ID=7891421

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01750T TR200101750T2 (tr) 1998-12-17 1999-12-07 KQT1 kanalı inhibitörlerinin bir ilacın üretiminde kullanımı.

Country Status (24)

Country Link
US (2) US6335363B1 (tr)
EP (1) EP1140042B1 (tr)
JP (1) JP2002532412A (tr)
KR (1) KR20010089574A (tr)
CN (1) CN1170528C (tr)
AR (1) AR021690A1 (tr)
AT (1) ATE390130T1 (tr)
AU (1) AU1559500A (tr)
BR (1) BR9916190A (tr)
CA (1) CA2355300A1 (tr)
CZ (1) CZ20012125A3 (tr)
DE (2) DE19858253A1 (tr)
HK (1) HK1041647B (tr)
HR (1) HRPK20010442B1 (tr)
HU (1) HUP0200152A3 (tr)
IL (1) IL143717A0 (tr)
NO (1) NO20012976L (tr)
NZ (1) NZ512408A (tr)
PL (1) PL349511A1 (tr)
RU (1) RU2238090C2 (tr)
SK (1) SK8562001A3 (tr)
TR (1) TR200101750T2 (tr)
WO (1) WO2000035429A1 (tr)
ZA (1) ZA200103620B (tr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1718677E (pt) * 2003-12-19 2012-07-18 Genentech Inc Fragmentos de anticorpo monovalentes úteis como agentes terapêuticos
MX2007001470A (es) * 2004-08-05 2007-03-26 Genentech Inc Antagonistas anti-cmet humanizados.
SG185966A1 (en) 2007-06-07 2012-12-28 Divergence Inc Control of ectoparasites
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
MX2013014687A (es) 2011-06-30 2014-02-17 Genentech Inc Formulaciones de anticuerpo anti-c-met.
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
EP3122900A1 (en) 2014-03-24 2017-02-01 F. Hoffmann-La Roche AG Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
EP2957557A1 (en) * 2014-06-17 2015-12-23 Novartis Tiergesundheit AG New compounds
WO2017136727A2 (en) 2016-02-05 2017-08-10 Denali Therapeutics Inc. Compounds, compositions and methods
ES2912295T3 (es) 2016-12-09 2022-05-25 Denali Therapeutics Inc Compuestos útiles como inhibidores de RIPK1
PE20200608A1 (es) * 2017-06-30 2020-03-10 Bayer Animal Health Gmbh Nuevos derivados de azaquinolina
TW202334164A (zh) 2022-01-12 2023-09-01 美商戴納立製藥公司 （Ｓ）－５－苄基－Ｎ－（５－甲基－４－側氧基－２，３，４，５－四氫吡啶並［３，２－ｂ］［１，４］氧氮呯－３－基）－４Ｈ－１，２，４－***－３－甲醯胺的晶型

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1044116C (zh) * 1993-11-29 1999-07-14 默里尔药物公司 用作il－1作用抑制剂的苯磺酰亚胺衍生物及其用途
US5559026A (en) * 1994-10-31 1996-09-24 American Cyanamid Company Genes encoding a novel family of potassium channels
DE19504379A1 (de) * 1995-02-10 1996-08-14 Hoechst Ag Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate
SK283837B6 (sk) 1996-05-15 2004-03-02 Hoechst Aktiengesellschaft Chrómany, spôsob ich prípravy, liečivá, ktoré ich obsahujú, a ich použitie
DE19706675A1 (de) 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19707656A1 (de) 1997-02-26 1998-08-27 Hoechst Ag Sulfonamid-substituierte anellierte 7-Ring-Verbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742508A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19742509A1 (de) 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DE19748469A1 (de) * 1997-11-03 1999-05-06 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Benzopyranderivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
KR20010089574A (ko) 2001-10-06
HK1041647A1 (en) 2002-07-19
CA2355300A1 (en) 2000-06-22
IL143717A0 (en) 2002-04-21
WO2000035429A1 (de) 2000-06-22
HUP0200152A3 (en) 2003-01-28
SK8562001A3 (en) 2001-12-03
EP1140042B1 (de) 2008-03-26
EP1140042A1 (de) 2001-10-10
JP2002532412A (ja) 2002-10-02
HRP20010442A2 (en) 2002-06-30
NO20012976D0 (no) 2001-06-15
CN1330540A (zh) 2002-01-09
NZ512408A (en) 2003-10-31
NO20012976L (no) 2001-08-06
ZA200103620B (en) 2002-06-04
HUP0200152A2 (hu) 2002-05-29
US6335363B1 (en) 2002-01-01
DE19858253A1 (de) 2000-06-21
AR021690A1 (es) 2002-07-31
HRPK20010442B1 (en) 2003-10-31
BR9916190A (pt) 2001-09-11
CZ20012125A3 (cs) 2001-09-12
RU2238090C2 (ru) 2004-10-20
DE59914712D1 (de) 2008-05-08
HK1041647B (zh) 2005-04-01
AU1559500A (en) 2000-07-03
PL349511A1 (en) 2002-07-29
CN1170528C (zh) 2004-10-13
US20020055537A1 (en) 2002-05-09
ATE390130T1 (de) 2008-04-15

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