TR199801133T2 - Tip II diyabetin tedavisi veya önlenmesi için nitrik oksit (NO) sentaz inhibitörü - Google Patents
Tip II diyabetin tedavisi veya önlenmesi için nitrik oksit (NO) sentaz inhibitörüInfo
- Publication number
- TR199801133T2 TR199801133T2 TR1998/01133T TR9801133T TR199801133T2 TR 199801133 T2 TR199801133 T2 TR 199801133T2 TR 1998/01133 T TR1998/01133 T TR 1998/01133T TR 9801133 T TR9801133 T TR 9801133T TR 199801133 T2 TR199801133 T2 TR 199801133T2
- Authority
- TR
- Turkey
- Prior art keywords
- diabetes
- type
- treatment
- synthase inhibitor
- prevention
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title 4
- 230000002265 prevention Effects 0.000 title 1
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 1
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 1
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Tip II diyabetini tedavisi ve/veya önleyici tedavisi için, bir insana veya insan disinda bir memeliye, toksik olmayan farmasötik olarak kabul edilebilir, etkili bir miktarda örnegin aminoguanidin gibi bir NO sintaz inhibitörünün veya farmasötik olarak kabul edilebilir bir türevinin verilmesini içeren bir yöntem.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9526331.5A GB9526331D0 (en) | 1995-12-22 | 1995-12-22 | Novel method |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199801133T2 true TR199801133T2 (tr) | 1998-09-21 |
Family
ID=10785930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1998/01133T TR199801133T2 (tr) | 1995-12-22 | 1996-12-18 | Tip II diyabetin tedavisi veya önlenmesi için nitrik oksit (NO) sentaz inhibitörü |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0868175B1 (tr) |
JP (1) | JP2000502668A (tr) |
KR (1) | KR19990076595A (tr) |
CN (1) | CN1209057A (tr) |
AT (1) | ATE232724T1 (tr) |
AU (1) | AU1379497A (tr) |
BR (1) | BR9612245A (tr) |
CA (1) | CA2240396A1 (tr) |
CZ (1) | CZ198698A3 (tr) |
DE (1) | DE69626307T2 (tr) |
ES (1) | ES2193285T3 (tr) |
GB (1) | GB9526331D0 (tr) |
HU (1) | HUP9903979A3 (tr) |
IL (1) | IL124870A0 (tr) |
MX (1) | MX9805098A (tr) |
NO (1) | NO982854L (tr) |
NZ (1) | NZ325307A (tr) |
PL (1) | PL327472A1 (tr) |
TR (1) | TR199801133T2 (tr) |
WO (1) | WO1997023204A1 (tr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999044598A2 (en) * | 1998-03-03 | 1999-09-10 | Board Of Regents, The University Of Texas System | Methods for inhibiting βcell apoptosis |
CN1660428B (zh) * | 2005-01-10 | 2011-09-07 | 王振军 | 一氧化氮合酶(nos)抑制剂用于治疗痔的新用途 |
ES2386831B1 (es) * | 2011-02-04 | 2013-07-08 | Servicio Andaluz De Salud | Uso de inhibidores de la actividad de las NO sintasas (NOS) y sus composiciones, en la elaboración de un medicamento para el tratamiento y la prevención de la prediabetes y la diabetes mellitus tipo 1 (DM1) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE793646T1 (de) * | 1994-11-23 | 1999-12-30 | Upjohn Co | Carboxylierte aminoguanidine zum behandlung von insulin-unabhängigem diabetes mellitus |
-
1995
- 1995-12-22 GB GBGB9526331.5A patent/GB9526331D0/en active Pending
-
1996
- 1996-12-18 BR BR9612245A patent/BR9612245A/pt not_active Application Discontinuation
- 1996-12-18 PL PL96327472A patent/PL327472A1/xx unknown
- 1996-12-18 HU HU9903979A patent/HUP9903979A3/hu unknown
- 1996-12-18 WO PCT/EP1996/005871 patent/WO1997023204A1/en active IP Right Grant
- 1996-12-18 AU AU13794/97A patent/AU1379497A/en not_active Abandoned
- 1996-12-18 KR KR1019980704676A patent/KR19990076595A/ko not_active Application Discontinuation
- 1996-12-18 NZ NZ325307A patent/NZ325307A/en unknown
- 1996-12-18 JP JP9523337A patent/JP2000502668A/ja not_active Ceased
- 1996-12-18 CA CA002240396A patent/CA2240396A1/en not_active Abandoned
- 1996-12-18 TR TR1998/01133T patent/TR199801133T2/tr unknown
- 1996-12-18 CZ CZ981986A patent/CZ198698A3/cs unknown
- 1996-12-18 CN CN96199955A patent/CN1209057A/zh active Pending
- 1996-12-18 ES ES96944077T patent/ES2193285T3/es not_active Expired - Lifetime
- 1996-12-18 DE DE69626307T patent/DE69626307T2/de not_active Expired - Fee Related
- 1996-12-18 IL IL12487096A patent/IL124870A0/xx unknown
- 1996-12-18 EP EP96944077A patent/EP0868175B1/en not_active Expired - Lifetime
- 1996-12-18 AT AT96944077T patent/ATE232724T1/de not_active IP Right Cessation
-
1998
- 1998-06-19 NO NO982854A patent/NO982854L/no not_active Application Discontinuation
- 1998-06-22 MX MX9805098A patent/MX9805098A/es unknown
Also Published As
Publication number | Publication date |
---|---|
HUP9903979A2 (hu) | 2000-03-28 |
EP0868175A1 (en) | 1998-10-07 |
NO982854D0 (no) | 1998-06-19 |
MX9805098A (es) | 1998-10-31 |
NZ325307A (en) | 1999-11-29 |
GB9526331D0 (en) | 1996-02-21 |
JP2000502668A (ja) | 2000-03-07 |
NO982854L (no) | 1998-06-19 |
PL327472A1 (en) | 1998-12-07 |
CZ198698A3 (cs) | 1999-06-16 |
CA2240396A1 (en) | 1997-07-03 |
CN1209057A (zh) | 1999-02-24 |
AU1379497A (en) | 1997-07-17 |
BR9612245A (pt) | 1999-07-13 |
WO1997023204A1 (en) | 1997-07-03 |
EP0868175B1 (en) | 2003-02-19 |
DE69626307D1 (de) | 2003-03-27 |
ATE232724T1 (de) | 2003-03-15 |
KR19990076595A (ko) | 1999-10-15 |
IL124870A0 (en) | 1999-01-26 |
HUP9903979A3 (en) | 2000-05-29 |
DE69626307T2 (de) | 2003-10-16 |
ES2193285T3 (es) | 2003-11-01 |
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