HUP9903978A2 - Proteinek glikozilezését inhibitáló vegyületek alkalmazása II. típusú diabetes kezelésére - Google Patents
Proteinek glikozilezését inhibitáló vegyületek alkalmazása II. típusú diabetes kezeléséreInfo
- Publication number
- HUP9903978A2 HUP9903978A2 HU9903978A HUP9903978A HUP9903978A2 HU P9903978 A2 HUP9903978 A2 HU P9903978A2 HU 9903978 A HU9903978 A HU 9903978A HU P9903978 A HUP9903978 A HU P9903978A HU P9903978 A2 HUP9903978 A2 HU P9903978A2
- Authority
- HU
- Hungary
- Prior art keywords
- type
- diabetes
- treatment
- inhibitors
- protein glycation
- Prior art date
Links
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 3
- 230000036252 glycation Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 229940121672 Glycosylation inhibitor Drugs 0.000 abstract 1
- 206010060378 Hyperinsulinaemia Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 230000003451 hyperinsulinaemic effect Effects 0.000 abstract 1
- 201000008980 hyperinsulinism Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Processing Of Solid Wastes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A találmány II. típűsú diabetes kezelésére és/vagy megelőzéséreszőlgáló eljárásra vőnatkőzik, amelynek sőrán egy embernek vagynemhűmán emlősnek egy prőteinglikőzilezési inhibitőrnak, példáűlaminő-gűanidinnek vagy gyógyászatilag elfőgadható származékánakhatásős, nemtőxikűs, gyógyászatilag elfőgadható mennyiségét adják be.Az egyik előnyös találmány szerinti megőldás II. típűsú diabetesprőfilaktikűs kezelési eljárására, különösen a hyperinsűlinaemiától ahyperglykaemiáig terjedő prőgresszió késleltetésére vagymegakadályőzására vőnatkőzik. ŕ
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9526330.7A GB9526330D0 (en) | 1995-12-22 | 1995-12-22 | Novel method |
GBGB9624914.9A GB9624914D0 (en) | 1996-11-29 | 1996-11-29 | Novel method |
PCT/EP1996/005870 WO1997023203A1 (en) | 1995-12-22 | 1996-12-18 | Aminoguanidine for treating niddm |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP9903978A2 true HUP9903978A2 (hu) | 2000-03-28 |
HUP9903978A3 HUP9903978A3 (en) | 2001-01-29 |
Family
ID=26308373
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9903978A HUP9903978A3 (en) | 1995-12-22 | 1996-12-18 | Use of inhibitors of protein glycation for the treatment of type ii diabetes |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0868176B1 (hu) |
JP (1) | JP2000502667A (hu) |
KR (1) | KR19990076594A (hu) |
CN (1) | CN1209058A (hu) |
AT (1) | ATE369847T1 (hu) |
AU (1) | AU1307697A (hu) |
BR (1) | BR9612250A (hu) |
CA (1) | CA2240492A1 (hu) |
CZ (1) | CZ198798A3 (hu) |
DE (1) | DE69637209T2 (hu) |
ES (1) | ES2292176T3 (hu) |
HU (1) | HUP9903978A3 (hu) |
IL (1) | IL124869A0 (hu) |
MX (1) | MX9805099A (hu) |
NO (1) | NO982853D0 (hu) |
PL (1) | PL327471A1 (hu) |
TR (1) | TR199801120T2 (hu) |
WO (1) | WO1997023203A1 (hu) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITRM20020625A1 (it) * | 2002-12-17 | 2004-06-18 | Sigma Tau Ind Farmaceuti | Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'. |
CN100411615C (zh) * | 2003-12-12 | 2008-08-20 | 上海第二医科大学附属瑞金医院 | 氨基胍对难愈创面的防治作用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4665192A (en) * | 1984-03-19 | 1987-05-12 | The Rockefeller University | 2-(2-furoyl)-4(5)-2(furanyl)-1H-imidazole |
WO1991012799A1 (en) * | 1990-02-28 | 1991-09-05 | The Upjohn Company | Use of 3-guanidinopropionic acid in the treatment and prevention of metabolic disorders |
GB2309900B (en) * | 1994-11-17 | 1998-03-25 | Mcdougall Gregory J | Electric fan heater |
-
1996
- 1996-12-18 KR KR1019980704675A patent/KR19990076594A/ko not_active Application Discontinuation
- 1996-12-18 ES ES96944681T patent/ES2292176T3/es not_active Expired - Lifetime
- 1996-12-18 DE DE69637209T patent/DE69637209T2/de not_active Expired - Fee Related
- 1996-12-18 JP JP09523336A patent/JP2000502667A/ja not_active Ceased
- 1996-12-18 CZ CZ981987A patent/CZ198798A3/cs unknown
- 1996-12-18 EP EP96944681A patent/EP0868176B1/en not_active Expired - Lifetime
- 1996-12-18 HU HU9903978A patent/HUP9903978A3/hu unknown
- 1996-12-18 AT AT96944681T patent/ATE369847T1/de not_active IP Right Cessation
- 1996-12-18 WO PCT/EP1996/005870 patent/WO1997023203A1/en active IP Right Grant
- 1996-12-18 BR BR9612250A patent/BR9612250A/pt not_active Application Discontinuation
- 1996-12-18 PL PL96327471A patent/PL327471A1/xx unknown
- 1996-12-18 CA CA002240492A patent/CA2240492A1/en not_active Abandoned
- 1996-12-18 IL IL12486996A patent/IL124869A0/xx unknown
- 1996-12-18 TR TR1998/01120T patent/TR199801120T2/xx unknown
- 1996-12-18 CN CN96199977A patent/CN1209058A/zh active Pending
- 1996-12-18 AU AU13076/97A patent/AU1307697A/en not_active Abandoned
-
1998
- 1998-06-19 NO NO982853A patent/NO982853D0/no not_active Application Discontinuation
- 1998-06-22 MX MX9805099A patent/MX9805099A/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO1997023203A1 (en) | 1997-07-03 |
EP0868176A1 (en) | 1998-10-07 |
NO982853L (no) | 1998-06-19 |
JP2000502667A (ja) | 2000-03-07 |
TR199801120T2 (xx) | 1998-09-21 |
ES2292176T3 (es) | 2008-03-01 |
HUP9903978A3 (en) | 2001-01-29 |
CN1209058A (zh) | 1999-02-24 |
DE69637209D1 (de) | 2007-09-27 |
CA2240492A1 (en) | 1997-07-03 |
EP0868176B1 (en) | 2007-08-15 |
PL327471A1 (en) | 1998-12-07 |
BR9612250A (pt) | 1999-07-13 |
DE69637209T2 (de) | 2008-05-08 |
NO982853D0 (no) | 1998-06-19 |
AU1307697A (en) | 1997-07-17 |
ATE369847T1 (de) | 2007-09-15 |
MX9805099A (es) | 1998-10-31 |
CZ198798A3 (cs) | 1999-06-16 |
KR19990076594A (ko) | 1999-10-15 |
IL124869A0 (en) | 1999-01-26 |
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