TN2009000371A1 - Composition pharmaceutique - Google Patents
Composition pharmaceutiqueInfo
- Publication number
- TN2009000371A1 TN2009000371A1 TNP2009000371A TN2009000371A TN2009000371A1 TN 2009000371 A1 TN2009000371 A1 TN 2009000371A1 TN P2009000371 A TNP2009000371 A TN P2009000371A TN 2009000371 A TN2009000371 A TN 2009000371A TN 2009000371 A1 TN2009000371 A1 TN 2009000371A1
- Authority
- TN
- Tunisia
- Prior art keywords
- pharmaceutical composition
- sorbitol
- tablet
- angiotensin
- surface area
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 2
- 239000000600 sorbitol Substances 0.000 abstract 2
- RMMXLENWKUUMAY-UHFFFAOYSA-N telmisartan Chemical compound CCCC1=NC2=C(C)C=C(C=3N(C4=CC=CC=C4N=3)C)C=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C(O)=O RMMXLENWKUUMAY-UHFFFAOYSA-N 0.000 abstract 2
- 239000005537 C09CA07 - Telmisartan Substances 0.000 abstract 1
- 239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 1
- 229940126317 angiotensin II receptor antagonist Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960005187 telmisartan Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
la présente invention concerne un comprimé ou une couche de comprimé pharmaceutique comprenant l'antagoniste du récepteur de l'angiotensine I I telmisartan sous forme amorphe, un agent basique et du sorbitol caractérisé en ce que le sorbitol présente une surface spécifique située entre 0,75 m2/g et 3,5 m2/g.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07104157A EP1970053A1 (fr) | 2007-03-14 | 2007-03-14 | Composition pharmaceutique |
PCT/EP2008/053009 WO2008110599A1 (fr) | 2007-03-14 | 2008-03-13 | Composition pharmaceutique |
Publications (1)
Publication Number | Publication Date |
---|---|
TN2009000371A1 true TN2009000371A1 (fr) | 2010-12-31 |
Family
ID=38179677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TNP2009000371A TN2009000371A1 (fr) | 2007-03-14 | 2009-09-11 | Composition pharmaceutique |
Country Status (36)
Country | Link |
---|---|
US (1) | US20100143465A1 (fr) |
EP (2) | EP1970053A1 (fr) |
JP (1) | JP5742045B2 (fr) |
KR (1) | KR101503674B1 (fr) |
CN (1) | CN101641084B (fr) |
AR (1) | AR065726A1 (fr) |
AT (1) | ATE493119T1 (fr) |
AU (1) | AU2008225754B2 (fr) |
BR (1) | BRPI0808797A2 (fr) |
CA (1) | CA2680608C (fr) |
CL (1) | CL2008000733A1 (fr) |
CO (1) | CO6220927A2 (fr) |
CY (1) | CY1111350T1 (fr) |
DE (1) | DE602008004217D1 (fr) |
DK (1) | DK2120884T3 (fr) |
EA (1) | EA018574B1 (fr) |
EC (1) | ECSP099629A (fr) |
ES (1) | ES2358770T3 (fr) |
HK (1) | HK1140692A1 (fr) |
HR (1) | HRP20110012T1 (fr) |
IL (1) | IL200125A (fr) |
MA (1) | MA31251B1 (fr) |
MX (1) | MX2009009201A (fr) |
MY (1) | MY145089A (fr) |
NZ (1) | NZ580185A (fr) |
PE (1) | PE20090165A1 (fr) |
PL (1) | PL2120884T3 (fr) |
PT (1) | PT2120884E (fr) |
RS (1) | RS51584B (fr) |
SI (1) | SI2120884T1 (fr) |
TN (1) | TN2009000371A1 (fr) |
TW (1) | TWI406678B (fr) |
UA (1) | UA96982C2 (fr) |
UY (1) | UY30961A1 (fr) |
WO (1) | WO2008110599A1 (fr) |
ZA (1) | ZA200905224B (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1908469A1 (fr) | 2006-10-06 | 2008-04-09 | Boehringer Ingelheim Vetmedica Gmbh | Antagonistes du récepteur de l'angiotensine II pour traiter des désordres sistémiques des chats |
US20100247649A1 (en) * | 2007-10-30 | 2010-09-30 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide |
WO2009135646A2 (fr) | 2008-05-05 | 2009-11-12 | Farmaprojects, Sa | Compositions pharmaceutiques stables et procédés de préparation desdites compositions adaptés à l’échelle industrielle |
CZ2008469A3 (cs) * | 2008-07-31 | 2009-10-29 | Zentiva, A. S. | Telmisartan tablety |
GB0822171D0 (en) * | 2008-12-04 | 2009-01-14 | Arrow Int Ltd | Temisartan formulations |
EP2432452B1 (fr) | 2009-05-20 | 2016-07-27 | Boehringer Ingelheim Vetmedica GmbH | Une solution pharmaceutique à boire contenant telmisartan |
MX2014011167A (es) * | 2012-03-19 | 2014-11-14 | Althera Life Sciencies Llc | Formulacion de tableta oral solida de rosuvastatina de liberacion inmediata y metformina de liberacion prolongada. |
JP6344678B2 (ja) * | 2013-09-27 | 2018-06-20 | キョーリンリメディオ株式会社 | テルミサルタン含有製剤及びその製造方法 |
WO2015119289A1 (fr) * | 2014-02-10 | 2015-08-13 | 富士フイルム株式会社 | Comprimé orodispersible |
BE1021954B1 (nl) * | 2014-06-05 | 2016-01-28 | Syral Belgium Nv | Samenstelling van sorbitol met lage friabiliteit |
FR3023128B1 (fr) | 2014-07-01 | 2017-11-10 | Roquette Freres | Nouvelle composition edulcorante |
JP5871294B1 (ja) * | 2015-02-27 | 2016-03-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 即時放出経口錠剤 |
KR20170001921A (ko) | 2015-06-26 | 2017-01-05 | 대원제약주식회사 | 안정성이 개선된 텔미사르탄을 함유하는 약제학적 조성물 및 이의 제조방법 |
CN106420739A (zh) * | 2016-10-31 | 2017-02-22 | 扬子江药业集团四川海蓉药业有限公司 | 一种替米沙坦氨氯地平双层片及其制备方法 |
CN106800537B (zh) | 2017-01-18 | 2019-02-01 | 广东隆赋药业股份有限公司 | 丁苯酞-替米沙坦杂合物及其制备方法和用途 |
CN109316451B (zh) * | 2017-07-31 | 2022-07-01 | 武汉朗来科技发展有限公司 | 治疗高血压和相关疾病的口服固体制剂 |
JP2021522299A (ja) | 2018-05-02 | 2021-08-30 | フェリング・ベー・フェー | 改良製剤 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3245170A1 (de) * | 1982-12-07 | 1984-06-07 | Merck Patent Gmbh, 6100 Darmstadt | Verbesserter sorbit, verfahren zur herstellung und verwendung |
AU1042199A (en) * | 1998-11-06 | 2000-05-29 | Boehringer Ingelheim International Gmbh | Antihypertensive medicaments containing lacidipine and telmisartan |
FR2787110B1 (fr) * | 1998-12-11 | 2001-02-16 | Roquette Freres | Sorbitol pulverulent et son procede de preparation |
RS52012B (en) * | 2002-01-16 | 2012-04-30 | Boehringer Ingelheim Pharma Gmbh&Co.Kg. | TWO-TABLET PHARMACEUTICAL TABLE CONTAINING TELMISARTAN AND DIURETIC AND ITS PREPARATION |
DE10244681A1 (de) * | 2002-09-24 | 2004-04-08 | Boehringer Ingelheim International Gmbh | Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung |
DE102004008804A1 (de) * | 2004-02-20 | 2005-09-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mehrschichttablette |
US20060078615A1 (en) * | 2004-10-12 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Bilayer tablet of telmisartan and simvastatin |
MX366895B (es) * | 2004-11-05 | 2019-07-30 | Boehringer Ingelheim Int Gmbh Star | Comprimido bicapa que comprende telmisartán y amlodipina. |
KR20070097511A (ko) * | 2004-12-17 | 2007-10-04 | 베링거 인겔하임 인터내셔날 게엠베하 | 텔미사르탄 및 하이드로클로로티아지드를 포함하는 배합치료 |
US20060159747A1 (en) * | 2004-12-17 | 2006-07-20 | Boehringer Ingelheim International Gmbh | Telmisartan and hydrochlorothiazide combination therapy |
-
2007
- 2007-03-14 EP EP07104157A patent/EP1970053A1/fr not_active Ceased
-
2008
- 2008-03-12 PE PE2008000465A patent/PE20090165A1/es not_active Application Discontinuation
- 2008-03-12 CL CL200800733A patent/CL2008000733A1/es unknown
- 2008-03-13 RS RS20110032A patent/RS51584B/en unknown
- 2008-03-13 PL PL08717753T patent/PL2120884T3/pl unknown
- 2008-03-13 ES ES08717753T patent/ES2358770T3/es active Active
- 2008-03-13 DE DE602008004217T patent/DE602008004217D1/de active Active
- 2008-03-13 EP EP08717753A patent/EP2120884B1/fr not_active Revoked
- 2008-03-13 WO PCT/EP2008/053009 patent/WO2008110599A1/fr active Application Filing
- 2008-03-13 UA UAA200910184A patent/UA96982C2/ru unknown
- 2008-03-13 DK DK08717753.1T patent/DK2120884T3/da active
- 2008-03-13 UY UY30961A patent/UY30961A1/es not_active Application Discontinuation
- 2008-03-13 SI SI200830179T patent/SI2120884T1/sl unknown
- 2008-03-13 CN CN2008800075975A patent/CN101641084B/zh active Active
- 2008-03-13 JP JP2009553147A patent/JP5742045B2/ja active Active
- 2008-03-13 TW TW097108903A patent/TWI406678B/zh not_active IP Right Cessation
- 2008-03-13 CA CA2680608A patent/CA2680608C/fr not_active Expired - Fee Related
- 2008-03-13 KR KR1020097021453A patent/KR101503674B1/ko active IP Right Review Request
- 2008-03-13 AU AU2008225754A patent/AU2008225754B2/en active Active
- 2008-03-13 MX MX2009009201A patent/MX2009009201A/es active IP Right Grant
- 2008-03-13 PT PT08717753T patent/PT2120884E/pt unknown
- 2008-03-13 NZ NZ580185A patent/NZ580185A/en unknown
- 2008-03-13 EA EA200901169A patent/EA018574B1/ru not_active IP Right Cessation
- 2008-03-13 MY MYPI20093767A patent/MY145089A/en unknown
- 2008-03-13 AT AT08717753T patent/ATE493119T1/de active
- 2008-03-13 AR ARP080101038A patent/AR065726A1/es active Pending
- 2008-03-13 US US12/530,489 patent/US20100143465A1/en not_active Abandoned
- 2008-03-13 BR BRPI0808797-0A patent/BRPI0808797A2/pt not_active Application Discontinuation
-
2009
- 2009-07-27 ZA ZA200905224A patent/ZA200905224B/xx unknown
- 2009-07-28 IL IL200125A patent/IL200125A/en active IP Right Grant
- 2009-09-09 CO CO09096619A patent/CO6220927A2/es not_active Application Discontinuation
- 2009-09-11 TN TNP2009000371A patent/TN2009000371A1/fr unknown
- 2009-09-11 MA MA32218A patent/MA31251B1/fr unknown
- 2009-09-11 EC EC2009009629A patent/ECSP099629A/es unknown
-
2010
- 2010-07-28 HK HK10107229.6A patent/HK1140692A1/xx not_active IP Right Cessation
-
2011
- 2011-01-10 HR HR20110012T patent/HRP20110012T1/hr unknown
- 2011-03-22 CY CY20111100312T patent/CY1111350T1/el unknown
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