SV1999000149A - 1,2,3,4 - tetrahidroquinolinas - 2 - metil - 4 - carboxiamino ref. pc10024/82736/bb - Google Patents
1,2,3,4 - tetrahidroquinolinas - 2 - metil - 4 - carboxiamino ref. pc10024/82736/bbInfo
- Publication number
- SV1999000149A SV1999000149A SV1999000149A SV1999000149A SV1999000149A SV 1999000149 A SV1999000149 A SV 1999000149A SV 1999000149 A SV1999000149 A SV 1999000149A SV 1999000149 A SV1999000149 A SV 1999000149A SV 1999000149 A SV1999000149 A SV 1999000149A
- Authority
- SV
- El Salvador
- Prior art keywords
- aluters
- inhibitors
- tetrahidroquinolinas
- carboxiamino
- ref
- Prior art date
Links
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 1
- 238000008214 LDL Cholesterol Methods 0.000 abstract 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003626 triacylglycerols Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
INHIBIDORES DE LA PROTEINA DE TRANSFERENCIA DEL ESTER COLESTERILICO , COMPOSICIONES FARMACEUTICAS QUE CONTIENEN DICHOS INHIBIDORES Y EL USO DE DICHOS INHIBIDORES PARA ELEVAR CIERTOS NIVELES DE LIPIDOS EN PLASMA, INCLUYENDO LIPOPROTEINAS DE ALTA DENSIDAD DE COLESTEROL Y PARA DISMINUIR CIERTOS OTROS NIVELES DE LIPIDOS EN PLASMA, TALES COMO LDL -COLESTEROL Y TRIGLICERIDOS, Y POR CONSIGUIENTE PARA TRATAR ENFERMEDADES QUE SON EXACERBADAS POR BAJOS NIVELES DE HDL-COLESTEROL Y/O ALTOS NIVELES DE LDL COLESTEROL Y TRIGLICERIDOS, TALES COMO ATEROSCLEROSIS Y ENFERMEDADES CARDIOVASCULARES EN ALGUNOS MAMIFEROS INCLUYENDO SERES HUMANOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10092998P | 1998-09-17 | 1998-09-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV1999000149A true SV1999000149A (es) | 2000-07-06 |
Family
ID=22282259
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV1999000149A SV1999000149A (es) | 1998-09-17 | 1999-09-10 | 1,2,3,4 - tetrahidroquinolinas - 2 - metil - 4 - carboxiamino ref. pc10024/82736/bb |
Country Status (25)
Country | Link |
---|---|
US (2) | US6147090A (es) |
EP (1) | EP1114033B1 (es) |
JP (1) | JP3655193B2 (es) |
AR (1) | AR021482A1 (es) |
AT (1) | ATE277906T1 (es) |
AU (1) | AU5439899A (es) |
BR (1) | BR9913842A (es) |
CA (1) | CA2344556A1 (es) |
CO (1) | CO5150220A1 (es) |
DE (1) | DE69920727T2 (es) |
DK (1) | DK1114033T3 (es) |
DZ (1) | DZ2889A1 (es) |
ES (1) | ES2228086T3 (es) |
GT (1) | GT199900149A (es) |
HN (1) | HN1999000155A (es) |
MA (1) | MA26687A1 (es) |
MY (1) | MY121838A (es) |
PA (1) | PA8481501A1 (es) |
PE (1) | PE20001048A1 (es) |
PT (1) | PT1114033E (es) |
SI (1) | SI1114033T1 (es) |
SV (1) | SV1999000149A (es) |
TN (1) | TNSN99172A1 (es) |
TW (1) | TWI232859B (es) |
WO (1) | WO2000017166A1 (es) |
Families Citing this family (87)
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DE19627431A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
US6197786B1 (en) * | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
US6462091B1 (en) | 1998-12-23 | 2002-10-08 | G.D. Searle & Co. | Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications |
-
1999
- 1999-09-07 US US09/391,273 patent/US6147090A/en not_active Expired - Fee Related
- 1999-09-08 PA PA19998481501A patent/PA8481501A1/es unknown
- 1999-09-09 HN HN1999000155A patent/HN1999000155A/es unknown
- 1999-09-10 TW TW088115690A patent/TWI232859B/zh not_active IP Right Cessation
- 1999-09-10 AR ARP990104556A patent/AR021482A1/es active IP Right Grant
- 1999-09-10 DK DK99940421T patent/DK1114033T3/da active
- 1999-09-10 EP EP99940421A patent/EP1114033B1/en not_active Expired - Lifetime
- 1999-09-10 CO CO99057639A patent/CO5150220A1/es unknown
- 1999-09-10 SI SI9930672T patent/SI1114033T1/xx unknown
- 1999-09-10 MY MYPI99003922A patent/MY121838A/en unknown
- 1999-09-10 PE PE1999000923A patent/PE20001048A1/es not_active Application Discontinuation
- 1999-09-10 DE DE69920727T patent/DE69920727T2/de not_active Expired - Fee Related
- 1999-09-10 JP JP2000574076A patent/JP3655193B2/ja not_active Expired - Fee Related
- 1999-09-10 AT AT99940421T patent/ATE277906T1/de not_active IP Right Cessation
- 1999-09-10 SV SV1999000149A patent/SV1999000149A/es not_active Application Discontinuation
- 1999-09-10 AU AU54398/99A patent/AU5439899A/en not_active Abandoned
- 1999-09-10 WO PCT/IB1999/001529 patent/WO2000017166A1/en active IP Right Grant
- 1999-09-10 PT PT99940421T patent/PT1114033E/pt unknown
- 1999-09-10 CA CA002344556A patent/CA2344556A1/en not_active Abandoned
- 1999-09-10 BR BR9913842-5A patent/BR9913842A/pt not_active Application Discontinuation
- 1999-09-10 GT GT199900149A patent/GT199900149A/es unknown
- 1999-09-10 ES ES99940421T patent/ES2228086T3/es not_active Expired - Lifetime
- 1999-09-13 TN TNTNSN99172A patent/TNSN99172A1/fr unknown
- 1999-09-13 MA MA25764A patent/MA26687A1/fr unknown
- 1999-09-17 DZ DZ990189A patent/DZ2889A1/xx active
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2000
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Also Published As
Publication number | Publication date |
---|---|
AU5439899A (en) | 2000-04-10 |
DZ2889A1 (fr) | 2003-12-15 |
TNSN99172A1 (fr) | 2005-11-10 |
AR021482A1 (es) | 2002-07-24 |
CO5150220A1 (es) | 2002-04-29 |
US6147090A (en) | 2000-11-14 |
DE69920727D1 (en) | 2004-11-04 |
BR9913842A (pt) | 2001-06-12 |
HN1999000155A (es) | 2000-01-12 |
DK1114033T3 (da) | 2004-12-20 |
ES2228086T3 (es) | 2005-04-01 |
DE69920727T2 (de) | 2006-03-09 |
MY121838A (en) | 2006-02-28 |
ATE277906T1 (de) | 2004-10-15 |
EP1114033A1 (en) | 2001-07-11 |
JP2002526477A (ja) | 2002-08-20 |
JP3655193B2 (ja) | 2005-06-02 |
PE20001048A1 (es) | 2000-10-17 |
PA8481501A1 (es) | 2001-12-14 |
TWI232859B (en) | 2005-05-21 |
CA2344556A1 (en) | 2000-03-30 |
US6395751B1 (en) | 2002-05-28 |
WO2000017166A1 (en) | 2000-03-30 |
EP1114033B1 (en) | 2004-09-29 |
PT1114033E (pt) | 2004-12-31 |
SI1114033T1 (en) | 2005-02-28 |
MA26687A1 (fr) | 2004-12-20 |
GT199900149A (es) | 2001-03-03 |
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