SI1114033T1 - 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as cetp inhibitors - Google Patents
4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as cetp inhibitorsInfo
- Publication number
- SI1114033T1 SI1114033T1 SI9930672T SI9930672T SI1114033T1 SI 1114033 T1 SI1114033 T1 SI 1114033T1 SI 9930672 T SI9930672 T SI 9930672T SI 9930672 T SI9930672 T SI 9930672T SI 1114033 T1 SI1114033 T1 SI 1114033T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tetrahydroquinolines
- carboxyamino
- methyl
- cetp inhibitors
- cetp
- Prior art date
Links
- LVHVPFOLBJZHDN-UHFFFAOYSA-N (2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)carbamic acid Chemical class C1=CC=C2NC(C)CC(NC(O)=O)C2=C1 LVHVPFOLBJZHDN-UHFFFAOYSA-N 0.000 title 1
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10092998P | 1998-09-17 | 1998-09-17 | |
| EP99940421A EP1114033B1 (en) | 1998-09-17 | 1999-09-10 | 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as cetp inhibitors |
| PCT/IB1999/001529 WO2000017166A1 (en) | 1998-09-17 | 1999-09-10 | 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as cetp inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1114033T1 true SI1114033T1 (en) | 2005-02-28 |
Family
ID=22282259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9930672T SI1114033T1 (en) | 1998-09-17 | 1999-09-10 | 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines as cetp inhibitors |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US6147090A (xx) |
| EP (1) | EP1114033B1 (xx) |
| JP (1) | JP3655193B2 (xx) |
| AR (1) | AR021482A1 (xx) |
| AT (1) | ATE277906T1 (xx) |
| AU (1) | AU5439899A (xx) |
| BR (1) | BR9913842A (xx) |
| CA (1) | CA2344556A1 (xx) |
| CO (1) | CO5150220A1 (xx) |
| DE (1) | DE69920727T2 (xx) |
| DK (1) | DK1114033T3 (xx) |
| DZ (1) | DZ2889A1 (xx) |
| ES (1) | ES2228086T3 (xx) |
| GT (1) | GT199900149A (xx) |
| HN (1) | HN1999000155A (xx) |
| MA (1) | MA26687A1 (xx) |
| MY (1) | MY121838A (xx) |
| PA (1) | PA8481501A1 (xx) |
| PE (1) | PE20001048A1 (xx) |
| PT (1) | PT1114033E (xx) |
| SI (1) | SI1114033T1 (xx) |
| SV (1) | SV1999000149A (xx) |
| TN (1) | TNSN99172A1 (xx) |
| TW (1) | TWI232859B (xx) |
| WO (1) | WO2000017166A1 (xx) |
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| US6147089A (en) * | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| ES2401598T3 (es) * | 2000-04-10 | 2013-04-22 | Teva Pharmaceutical Industries, Ltd. | Composiciones farmacéuticas estables que contienen ácidos 7-sustituido-3,5-dihidroxiheptanoicos o ácidos 7-sustituido-3,5-dihidroxiheptenoicos |
| USRE44578E1 (en) | 2000-04-10 | 2013-11-05 | Teva Pharmaceutical Industries, Ltd. | Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids |
| US7115279B2 (en) | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
| US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
| EP1911462A3 (en) | 2001-01-26 | 2011-11-30 | Schering Corporation | Compositions comprising a sterol absorption inhibitor |
| US20060287254A1 (en) * | 2001-01-26 | 2006-12-21 | Schering Corporation | Use of substituted azetidinone compounds for the treatment of sitosterolemia |
| WO2002078625A2 (en) * | 2001-03-28 | 2002-10-10 | Pharmacia Corporation | Therapeutic combinations for cardiovascular and inflammatory indications |
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- 1999-09-08 PA PA19998481501A patent/PA8481501A1/es unknown
- 1999-09-09 HN HN1999000155A patent/HN1999000155A/es unknown
- 1999-09-10 JP JP2000574076A patent/JP3655193B2/ja not_active Expired - Fee Related
- 1999-09-10 PE PE1999000923A patent/PE20001048A1/es not_active Application Discontinuation
- 1999-09-10 BR BR9913842-5A patent/BR9913842A/pt not_active Application Discontinuation
- 1999-09-10 AU AU54398/99A patent/AU5439899A/en not_active Abandoned
- 1999-09-10 EP EP99940421A patent/EP1114033B1/en not_active Expired - Lifetime
- 1999-09-10 TW TW088115690A patent/TWI232859B/zh not_active IP Right Cessation
- 1999-09-10 SV SV1999000149A patent/SV1999000149A/es not_active Application Discontinuation
- 1999-09-10 GT GT199900149A patent/GT199900149A/es unknown
- 1999-09-10 DE DE69920727T patent/DE69920727T2/de not_active Expired - Fee Related
- 1999-09-10 CO CO99057639A patent/CO5150220A1/es unknown
- 1999-09-10 PT PT99940421T patent/PT1114033E/pt unknown
- 1999-09-10 WO PCT/IB1999/001529 patent/WO2000017166A1/en active IP Right Grant
- 1999-09-10 AT AT99940421T patent/ATE277906T1/de not_active IP Right Cessation
- 1999-09-10 SI SI9930672T patent/SI1114033T1/xx unknown
- 1999-09-10 MY MYPI99003922A patent/MY121838A/en unknown
- 1999-09-10 ES ES99940421T patent/ES2228086T3/es not_active Expired - Lifetime
- 1999-09-10 AR ARP990104556A patent/AR021482A1/es active IP Right Grant
- 1999-09-10 DK DK99940421T patent/DK1114033T3/da active
- 1999-09-10 CA CA002344556A patent/CA2344556A1/en not_active Abandoned
- 1999-09-13 TN TNTNSN99172A patent/TNSN99172A1/fr unknown
- 1999-09-13 MA MA25764A patent/MA26687A1/fr unknown
- 1999-09-17 DZ DZ990189A patent/DZ2889A1/xx active
-
2000
- 2000-09-27 US US09/671,400 patent/US6395751B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2228086T3 (es) | 2005-04-01 |
| JP3655193B2 (ja) | 2005-06-02 |
| AR021482A1 (es) | 2002-07-24 |
| CO5150220A1 (es) | 2002-04-29 |
| DZ2889A1 (fr) | 2003-12-15 |
| TWI232859B (en) | 2005-05-21 |
| PE20001048A1 (es) | 2000-10-17 |
| CA2344556A1 (en) | 2000-03-30 |
| JP2002526477A (ja) | 2002-08-20 |
| EP1114033A1 (en) | 2001-07-11 |
| HN1999000155A (es) | 2000-01-12 |
| TNSN99172A1 (fr) | 2005-11-10 |
| US6395751B1 (en) | 2002-05-28 |
| SV1999000149A (es) | 2000-07-06 |
| DE69920727T2 (de) | 2006-03-09 |
| BR9913842A (pt) | 2001-06-12 |
| PT1114033E (pt) | 2004-12-31 |
| AU5439899A (en) | 2000-04-10 |
| WO2000017166A1 (en) | 2000-03-30 |
| MY121838A (en) | 2006-02-28 |
| PA8481501A1 (es) | 2001-12-14 |
| GT199900149A (es) | 2001-03-03 |
| US6147090A (en) | 2000-11-14 |
| MA26687A1 (fr) | 2004-12-20 |
| DK1114033T3 (da) | 2004-12-20 |
| DE69920727D1 (en) | 2004-11-04 |
| EP1114033B1 (en) | 2004-09-29 |
| ATE277906T1 (de) | 2004-10-15 |
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