SK2142002A3 - Methods and compositions useful for modulation of angiogenesis using protein kinase raf and ras - Google Patents

Methods and compositions useful for modulation of angiogenesis using protein kinase raf and ras Download PDF

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Publication number
SK2142002A3
SK2142002A3 SK214-2002A SK2142002A SK2142002A3 SK 2142002 A3 SK2142002 A3 SK 2142002A3 SK 2142002 A SK2142002 A SK 2142002A SK 2142002 A3 SK2142002 A3 SK 2142002A3
Authority
SK
Slovakia
Prior art keywords
protein
ras
raf
angiogenesis
tissue
Prior art date
Application number
SK214-2002A
Other languages
English (en)
Slovak (sk)
Inventor
John Hood
Brian Eliceiri
David A Cheresh
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of SK2142002A3 publication Critical patent/SK2142002A3/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SK214-2002A 1999-08-13 2000-08-11 Methods and compositions useful for modulation of angiogenesis using protein kinase raf and ras SK2142002A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14892499P 1999-08-13 1999-08-13
US21595100P 2000-07-05 2000-07-05
PCT/US2000/021842 WO2001012210A1 (en) 1999-08-13 2000-08-11 Methods and compositions useful for modulation of angiogenesis using tyrosine kinase raf and ras

Publications (1)

Publication Number Publication Date
SK2142002A3 true SK2142002A3 (en) 2002-07-02

Family

ID=26846311

Family Applications (1)

Application Number Title Priority Date Filing Date
SK214-2002A SK2142002A3 (en) 1999-08-13 2000-08-11 Methods and compositions useful for modulation of angiogenesis using protein kinase raf and ras

Country Status (17)

Country Link
US (1) US20060040853A1 (hu)
EP (1) EP1210099A4 (hu)
JP (1) JP2003507337A (hu)
KR (2) KR100759241B1 (hu)
CN (1) CN1208087C (hu)
AU (1) AU781877B2 (hu)
BR (1) BR0013228A (hu)
CA (1) CA2380966A1 (hu)
CZ (1) CZ2002449A3 (hu)
HK (1) HK1050856A1 (hu)
HU (1) HUP0300923A3 (hu)
MX (1) MXPA02001553A (hu)
NO (1) NO20020718L (hu)
PL (1) PL364928A1 (hu)
RU (1) RU2257911C2 (hu)
SK (1) SK2142002A3 (hu)
WO (1) WO2001012210A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002026246A2 (en) * 2000-09-29 2002-04-04 Gsf-Forschungszentrum Für Umwelt Und Gesundheit, Gmbh Pharmaceutical compositions comprising polynucleotides encoding a raf protein
US8486941B2 (en) * 2007-03-12 2013-07-16 Ym Biosciences Australia Pty Ltd Phenyl amino pyrimidine compounds and uses thereof
CN101970670B (zh) * 2008-01-14 2013-08-21 健泰科生物技术公司 使用egfl8拮抗剂抑制血管发生的方法
EP2329854A3 (de) * 2009-12-04 2014-02-19 Biotronik VI Patent AG Implantatbeschichtung mit Nukleinsäuren
CN102766601B (zh) * 2011-11-17 2015-12-16 中山大学肿瘤防治中心 含有可诱导型癌基因的细胞系及其建立方法、应用
RU2662781C2 (ru) * 2014-06-03 2018-07-30 Эррера Артуро Солис Животные модели ангиогенеза роговицы и эктазированных состояний роговицы, их способы получения и способы применения
RU2728870C2 (ru) * 2017-10-12 2020-07-31 Федеральное государственное бюджетное учреждение "Российский научный центр рентгенорадиологии" Министерства здравоохранения российской федерации (ФГБУ "РНЦРР" Минздрава России) Полипептиды для лечения онкологических заболеваний
EP4135738A2 (en) * 2020-04-15 2023-02-22 Cohbar Inc. Method of treating coronavirus infections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156841A (en) * 1988-08-26 1992-10-20 United States Of America Anti-tumor vaccine
US5618670A (en) 1988-08-26 1997-04-08 The United States Of America As Represented By The Department Of Health & Human Services Detection method for c-raf-1 genes
US5656612A (en) * 1994-05-31 1997-08-12 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of raf gene expression
US5597719A (en) 1994-07-14 1997-01-28 Onyx Pharmaceuticals, Inc. Interaction of RAF-1 and 14-3-3 proteins
US5795910A (en) * 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
WO1998021585A1 (en) * 1996-11-15 1998-05-22 Cornell Research Foundation, Inc. Activated ras interaction assay
US6376471B1 (en) * 1997-10-10 2002-04-23 Johns Hopkins University Gene delivery compositions and methods

Also Published As

Publication number Publication date
KR20020032553A (ko) 2002-05-03
AU781877B2 (en) 2005-06-16
BR0013228A (pt) 2003-06-17
KR100805098B1 (ko) 2008-02-20
CA2380966A1 (en) 2001-02-22
EP1210099A4 (en) 2006-01-18
NO20020718L (no) 2002-04-10
HUP0300923A3 (en) 2005-12-28
CZ2002449A3 (cs) 2002-08-14
JP2003507337A (ja) 2003-02-25
EP1210099A1 (en) 2002-06-05
WO2001012210A1 (en) 2001-02-22
PL364928A1 (en) 2004-12-27
CN1208087C (zh) 2005-06-29
US20060040853A1 (en) 2006-02-23
KR100759241B1 (ko) 2007-09-18
HK1050856A1 (en) 2003-07-11
CN1378457A (zh) 2002-11-06
HUP0300923A2 (hu) 2003-07-28
RU2257911C2 (ru) 2005-08-10
AU6763300A (en) 2001-03-13
KR20070067210A (ko) 2007-06-27
MXPA02001553A (es) 2003-05-23
NO20020718D0 (no) 2002-02-12
WO2001012210A9 (en) 2002-09-12

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