SI2999701T1 - 2-fenilimidazo(1,2-a)pirimidini kot sredstva za slikanje - Google Patents
2-fenilimidazo(1,2-a)pirimidini kot sredstva za slikanjeInfo
- Publication number
- SI2999701T1 SI2999701T1 SI201430251T SI201430251T SI2999701T1 SI 2999701 T1 SI2999701 T1 SI 2999701T1 SI 201430251 T SI201430251 T SI 201430251T SI 201430251 T SI201430251 T SI 201430251T SI 2999701 T1 SI2999701 T1 SI 2999701T1
- Authority
- SI
- Slovenia
- Prior art keywords
- phenylimidazo
- pyrimidines
- imaging agents
- imaging
- agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13168830 | 2013-05-23 | ||
| PCT/EP2014/060203 WO2014187762A1 (en) | 2013-05-23 | 2014-05-19 | 2-phenylimidazo[1,2-a]pyrimidines as imaging agents |
| EP14724757.1A EP2999701B1 (en) | 2013-05-23 | 2014-05-19 | 2-phenylimidazo[1,2-a]pyrimidines as imaging agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2999701T1 true SI2999701T1 (sl) | 2017-08-31 |
Family
ID=48446195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201430251T SI2999701T1 (sl) | 2013-05-23 | 2014-05-19 | 2-fenilimidazo(1,2-a)pirimidini kot sredstva za slikanje |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9801961B2 (sl) |
| EP (1) | EP2999701B1 (sl) |
| JP (1) | JP6130055B2 (sl) |
| KR (1) | KR101770494B1 (sl) |
| CN (1) | CN105229009B (sl) |
| AR (1) | AR096371A1 (sl) |
| AU (1) | AU2014270524B2 (sl) |
| BR (1) | BR112015025140A2 (sl) |
| CA (1) | CA2907605A1 (sl) |
| DK (1) | DK2999701T3 (sl) |
| ES (1) | ES2629389T3 (sl) |
| HK (1) | HK1213558A1 (sl) |
| HU (1) | HUE033612T2 (sl) |
| MX (1) | MX2015015893A (sl) |
| PL (1) | PL2999701T3 (sl) |
| RU (1) | RU2665580C2 (sl) |
| SG (1) | SG11201509503QA (sl) |
| SI (1) | SI2999701T1 (sl) |
| TW (1) | TW201500360A (sl) |
| WO (1) | WO2014187762A1 (sl) |
| ZA (1) | ZA201506570B (sl) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2779532T3 (es) | 2015-04-08 | 2020-08-18 | Bayer Cropscience Ag | Derivados de imidazo[1,2a]piridin-2-ilo como pesticidas y sus productos intermedios |
| ES2882667T3 (es) | 2015-08-07 | 2021-12-02 | Bayer Cropscience Ag | Derivados heterocíclicos condensados sustituidos por 2-(het)arilo como pesticidas |
| RU2729187C1 (ru) * | 2015-09-29 | 2020-08-05 | Онкотерапи Сайенс, Инк. | Бициклическое соединение и его применение для ингибирования suv39h2 |
| ES2894301T3 (es) | 2015-10-26 | 2022-02-14 | Bayer Cropscience Ag | Derivados de heterociclos bicíclicos condensados como pesticidas |
| WO2017093180A1 (de) | 2015-12-01 | 2017-06-08 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CN105582168A (zh) * | 2016-01-08 | 2016-05-18 | 王明强 | 一种治疗体弱多病、元气不足、免疫力低下的中药药剂 |
| WO2017144341A1 (de) | 2016-02-23 | 2017-08-31 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2017174414A1 (de) | 2016-04-05 | 2017-10-12 | Bayer Cropscience Aktiengesellschaft | Naphthalin-derivate als schädlingsbekämpfungsmittel |
| EP3241830A1 (de) | 2016-05-04 | 2017-11-08 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3487860B1 (de) | 2016-07-19 | 2021-04-14 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2018015546A1 (en) | 2016-07-22 | 2018-01-25 | Ac Immune S.A. | Compounds for imaging tau protein aggregates |
| SG11201811311VA (en) | 2016-07-22 | 2019-01-30 | Ac Immune Sa | Compounds for imaging tau protein aggregates |
| WO2018033455A1 (de) | 2016-08-15 | 2018-02-22 | Bayer Cropscience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| MX2019003136A (es) | 2016-09-19 | 2019-07-18 | Bayer Cropscience Ag | Derivados de pirazolo [1,5-a]piridina y su uso como pesticidas. |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
| AU2018208422B2 (en) | 2017-01-10 | 2021-11-11 | Bayer Aktiengesellschaft | Heterocyclene derivatives as pest control agents |
| ES2867600T3 (es) | 2017-01-10 | 2021-10-20 | Bayer Ag | Derivados de imidazol como pesticidas |
| WO2018138050A1 (de) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2018197257A1 (de) | 2017-04-24 | 2018-11-01 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| JP6831802B2 (ja) * | 2018-01-12 | 2021-02-17 | 上海富吉医療器械有限公司Ｓｈａｎｇｈａｉ Ｃｈａｒｔｗｅｌｌ Ｍｅｄｉｃａｌ Ｉｎｓｔｒｕｍｅｎｔ Ｃｏ．， Ｌｔｄ． | 放射性核種標識化合物及びこれを含有するイメージング剤 |
| EP3305786A3 (de) | 2018-01-22 | 2018-07-25 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| US20210041447A1 (en) | 2018-01-24 | 2021-02-11 | Ac Immune Sa | Azacarboline compounds for the detection of tau aggregates |
| EP3743423A1 (en) | 2018-01-24 | 2020-12-02 | AC Immune SA | Gamma-carboline compounds for the detection of tau aggregates |
| EP3755700B1 (de) | 2018-02-21 | 2021-11-24 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CA3102038A1 (en) * | 2018-06-08 | 2019-12-12 | Ac Immune Sa | Novel compounds for diagnosis |
| EP3931192B1 (de) | 2019-02-26 | 2024-03-20 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CN113710669A (zh) | 2019-02-26 | 2021-11-26 | 拜耳公司 | 作为农药的稠合双环杂环衍生物 |
| CN114890955A (zh) * | 2022-06-23 | 2022-08-12 | 江西瑞威尔生物科技有限公司 | 一种n取代吗啉类有机化合物的制备工艺 |
| US20240101563A1 (en) * | 2022-07-28 | 2024-03-28 | Ac Immune Sa | Novel compounds |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1255406C (zh) * | 1999-11-10 | 2006-05-10 | 奥索-麦克尼尔药品公司 | 取代的2－芳基－3－(杂芳基)－咪唑并[1，2－a]嘧啶类化合物以及相关的药物组合物和方法 |
| US6642229B2 (en) * | 2000-05-24 | 2003-11-04 | Merck Sharp & Dohme Ltd. | 3-Phenyl-imidazo-pyrimidine derivatives as ligands for GABA receptors |
| AU2006261917A1 (en) | 2005-06-24 | 2007-01-04 | The Trustees Of The University Of Pennsylvania | Radiolabeled-pegylation of ligands for use as imaging agents |
| US20080219922A1 (en) | 2005-09-12 | 2008-09-11 | Goodman Mark M | Alzheimer's Disease Imaging Agents |
| WO2007034282A2 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists |
| JP4738419B2 (ja) * | 2005-11-30 | 2011-08-03 | 富士フイルムＲｉファーマ株式会社 | アミロイドの凝集及び／又は沈着に起因する疾患の診断薬及び治療薬 |
| US7700616B2 (en) * | 2006-05-08 | 2010-04-20 | Molecular Neuroimaging, Llc. | Compounds and amyloid probes thereof for therapeutic and imaging uses |
| KR20090010987A (ko) | 2006-05-19 | 2009-01-30 | 니혼 메디피직스 가부시키가이샤 | 신규 아밀로이드 친화성 화합물 |
| US8691187B2 (en) * | 2009-03-23 | 2014-04-08 | Eli Lilly And Company | Imaging agents for detecting neurological disorders |
| US8410117B2 (en) * | 2010-03-26 | 2013-04-02 | Hoffmann-La Roche Inc. | Imidazopyrimidine derivatives |
| BR112015027015A2 (pt) * | 2013-04-29 | 2017-07-25 | Hoffmann La Roche | derivados de 2-fenil ou 2-hetaril imidazol[1,2-a]piridina |
-
2014
- 2014-05-19 JP JP2016514351A patent/JP6130055B2/ja active Active
- 2014-05-19 BR BR112015025140A patent/BR112015025140A2/pt not_active Application Discontinuation
- 2014-05-19 SG SG11201509503QA patent/SG11201509503QA/en unknown
- 2014-05-19 DK DK14724757.1T patent/DK2999701T3/en active
- 2014-05-19 CN CN201480029084.XA patent/CN105229009B/zh active Active
- 2014-05-19 CA CA2907605A patent/CA2907605A1/en not_active Abandoned
- 2014-05-19 MX MX2015015893A patent/MX2015015893A/es unknown
- 2014-05-19 WO PCT/EP2014/060203 patent/WO2014187762A1/en active Application Filing
- 2014-05-19 SI SI201430251T patent/SI2999701T1/sl unknown
- 2014-05-19 RU RU2015149528A patent/RU2665580C2/ru not_active IP Right Cessation
- 2014-05-19 PL PL14724757T patent/PL2999701T3/pl unknown
- 2014-05-19 ES ES14724757.1T patent/ES2629389T3/es active Active
- 2014-05-19 AU AU2014270524A patent/AU2014270524B2/en not_active Ceased
- 2014-05-19 EP EP14724757.1A patent/EP2999701B1/en active Active
- 2014-05-19 KR KR1020157033039A patent/KR101770494B1/ko active IP Right Grant
- 2014-05-19 HU HUE14724757A patent/HUE033612T2/en unknown
- 2014-05-20 TW TW103117655A patent/TW201500360A/zh unknown
- 2014-05-21 AR ARP140102015A patent/AR096371A1/es unknown
-
2015
- 2015-09-07 ZA ZA2015/06570A patent/ZA201506570B/en unknown
- 2015-11-19 US US14/945,969 patent/US9801961B2/en active Active
-
2016
- 2016-02-11 HK HK16101490.5A patent/HK1213558A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2999701B1 (en) | 2017-04-12 |
| RU2015149528A (ru) | 2017-06-28 |
| AU2014270524A8 (en) | 2015-09-24 |
| JP2016520091A (ja) | 2016-07-11 |
| CA2907605A1 (en) | 2014-11-27 |
| ES2629389T3 (es) | 2017-08-09 |
| DK2999701T3 (en) | 2017-07-10 |
| US9801961B2 (en) | 2017-10-31 |
| AU2014270524B2 (en) | 2018-01-04 |
| TW201500360A (zh) | 2015-01-01 |
| PL2999701T3 (pl) | 2017-09-29 |
| WO2014187762A1 (en) | 2014-11-27 |
| BR112015025140A2 (pt) | 2017-07-18 |
| JP6130055B2 (ja) | 2017-05-17 |
| HK1213558A1 (zh) | 2016-07-08 |
| AR096371A1 (es) | 2015-12-23 |
| AU2014270524A1 (en) | 2015-09-17 |
| SG11201509503QA (en) | 2015-12-30 |
| RU2015149528A3 (sl) | 2018-03-22 |
| KR101770494B1 (ko) | 2017-08-22 |
| HUE033612T2 (en) | 2017-12-28 |
| CN105229009A (zh) | 2016-01-06 |
| RU2665580C2 (ru) | 2018-08-31 |
| MX2015015893A (es) | 2016-03-04 |
| EP2999701A1 (en) | 2016-03-30 |
| ZA201506570B (en) | 2017-02-22 |
| US20170128598A1 (en) | 2017-05-11 |
| KR20150144796A (ko) | 2015-12-28 |
| CN105229009B (zh) | 2017-09-29 |
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