SI2691083T1 - Farmacevtski sestavek sitagliptina - Google Patents

Farmacevtski sestavek sitagliptina

Info

Publication number
SI2691083T1
SI2691083T1 SI201231106T SI201231106T SI2691083T1 SI 2691083 T1 SI2691083 T1 SI 2691083T1 SI 201231106 T SI201231106 T SI 201231106T SI 201231106 T SI201231106 T SI 201231106T SI 2691083 T1 SI2691083 T1 SI 2691083T1
Authority
SI
Slovenia
Prior art keywords
sitagliptin
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
SI201231106T
Other languages
English (en)
Inventor
Maja Preskar
Vesna Kroselj
Sabina Trost
Lucija Hvalec
Alen Kljajic
Polona Bukovec
Original Assignee
Krka, D.D., Novo Mesto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka, D.D., Novo Mesto filed Critical Krka, D.D., Novo Mesto
Publication of SI2691083T1 publication Critical patent/SI2691083T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201231106T 2011-03-29 2012-03-29 Farmacevtski sestavek sitagliptina SI2691083T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201100115 2011-03-29
PCT/EP2012/055736 WO2012131005A1 (en) 2011-03-29 2012-03-29 Pharmaceutical composition of sitagliptin
EP12711399.1A EP2691083B1 (en) 2011-03-29 2012-03-29 Pharmaceutical composition of sitagliptin

Publications (1)

Publication Number Publication Date
SI2691083T1 true SI2691083T1 (sl) 2017-12-29

Family

ID=45922684

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231106T SI2691083T1 (sl) 2011-03-29 2012-03-29 Farmacevtski sestavek sitagliptina

Country Status (4)

Country Link
EP (1) EP2691083B1 (sl)
EA (1) EA029539B8 (sl)
SI (1) SI2691083T1 (sl)
WO (1) WO2012131005A1 (sl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140350023A1 (en) * 2011-12-08 2014-11-27 Ranbaxy Laboratories Limited Amorphous form of sitagliptin salts
IN2014MU00212A (sl) * 2014-01-21 2015-08-28 Cadila Healthcare Ltd
WO2015114152A1 (en) * 2014-02-03 2015-08-06 Galenicum Health S.L. Stable pharmaceutical compositions containing sitagliptin in the form of immediate release tablets
IN2014MU00651A (sl) 2014-02-25 2015-10-23 Cadila Healthcare Ltd
CN108144065B (zh) * 2016-12-06 2023-05-16 江苏恒瑞医药股份有限公司 一种dpp-4抑制剂的药物组合物
MX2016016260A (es) 2016-12-08 2018-06-07 Alparis Sa De Cv Nuevas formas solidas de sitagliptina.
CA3081358A1 (en) * 2017-11-10 2019-05-16 Dispersol Technologies, Llc Improved drug formulations
WO2021076066A1 (en) 2019-10-14 2021-04-22 Santa Farma İlaç Sanayi̇ A.Ş. Oral formulations comprising sitagliptin hci monohydrate with improved pharmaceutical characteristics
EP3811930A1 (en) * 2019-10-24 2021-04-28 Authenda Pharmaceuticals AG Oral gliptin compositions and method for preparation thereof
GR1010089B (el) 2020-09-15 2021-09-27 Φαρματεν Α.Β.Ε.Ε. Στερεη φαρμακοτεχνικη μορφη περιεχουσα σιταγλιπτινη και μεθοδος παρασκευης αυτης
CN116459227A (zh) * 2023-05-11 2023-07-21 宙晟智维生命科学(上海)有限公司 一种西格列汀片及其制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74912C2 (en) 2001-07-06 2006-02-15 Merck & Co Inc Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes
JO2625B1 (en) 2003-06-24 2011-11-01 ميرك شارب اند دوم كوربوريشن Phosphoric acid salts of dipeptidyl betidase inhibitor 4
EP1662876A4 (en) 2003-09-02 2009-01-14 Merck & Co Inc NOVEL CRYSTALLINE FORMS OF A PHOSPHORIC ACID SALT OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR
WO2005030127A2 (en) 2003-09-23 2005-04-07 Merck & Co., Inc. Novel crystalline form of a phosphoric acid salt of a dipeptidyl peptidase-iv inhibitor
WO2005072530A1 (en) 2004-01-16 2005-08-11 Merck & Co., Inc. Novel crystalline salts of a dipeptidyl peptidase-iv inhibitor
WO2006033848A1 (en) 2004-09-15 2006-03-30 Merck & Co., Inc. Amorphous form of a phosphoric acid salt of a dipeptidyl peptidase-iv inhibitor
WO2007035198A2 (en) 2005-07-25 2007-03-29 Merck & Co., Inc. Dodecylsulfate salt of a dipeptidyl peptidase-iv inhibitor
KR20070111099A (ko) 2006-05-16 2007-11-21 영진약품공업주식회사 시타글립틴 염산염의 신규 결정형, 이의 제조 방법과 이를포함하는 약학적 조성물
ATE446946T1 (de) * 2006-06-27 2009-11-15 Sandoz Ag Neues verfahren zur salzherstellung
US20080064701A1 (en) * 2007-04-24 2008-03-13 Ramesh Sesha Anti-diabetic combinations
US20070172525A1 (en) * 2007-03-15 2007-07-26 Ramesh Sesha Anti-diabetic combinations
WO2009084024A2 (en) 2007-11-02 2009-07-09 Glenmark Generics Limited A process for the preparation of r-sit agliptin and its pharmaceutically acceptable salts thereof
US20090221595A1 (en) 2007-11-26 2009-09-03 Nurit Perlman Crystalline form of sitagliptin
EP2679590A1 (en) 2007-12-20 2014-01-01 Dr. Reddy's Laboratories Ltd. Processes for the Preparation of Sitagliptin and Pharmaceutically acceptable Salts thereof
AU2009220444A1 (en) * 2008-03-04 2009-09-11 Merck Sharp & Dohme Corp. Pharmaceutical compositions of a combination of metformin and a dipeptidyl peptidase-IV inhibitor
TW201000485A (en) 2008-03-25 2010-01-01 Teva Pharma Crystalline forms of sitagliptin phosphate
US20090247532A1 (en) 2008-03-28 2009-10-01 Mae De Ltd. Crystalline polymorph of sitagliptin phosphate and its preparation
EP2650297A1 (en) 2008-07-03 2013-10-16 Ratiopharm GmbH Crystalline salts of sitagliptin
US20100069637A1 (en) 2008-07-29 2010-03-18 Medichem S.A. CRYSTALLINE SALT FORMS OF A 5,6,7,8-TETRAHYDRO-1,2,4-TRIAZOLO[4,3-a]PYRAZINE DERIVATIVE
US8476437B2 (en) 2008-08-27 2013-07-02 Cadila Healthcare Limited Process for preparation of (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro [1,2,4]-triazolo[4,3-a]pyrazin-7(8H)-yl]-l-(2,4,5-trifluorophenyl)butan-2-amine and new impurities in preparation thereof
EP2218721A1 (en) 2009-02-11 2010-08-18 LEK Pharmaceuticals d.d. Novel salts of sitagliptin
US8329696B2 (en) * 2009-03-30 2012-12-11 Teva Pharmaceuticals Industries Ltd. Solid state forms of sitagliptin salts
WO2010122578A2 (en) 2009-04-20 2010-10-28 Msn Laboratories Limited Process for the preparation of sitagliptin and its intermediates
WO2010131035A1 (en) 2009-05-11 2010-11-18 Generics [Uk] Limited Novel crystalline polymorph of sitagliptin dihydrogen phosphate
CN102933576A (zh) * 2010-04-08 2013-02-13 百时美施贵宝公司 作为gpr119调节剂的嘧啶基哌啶基氧基吡啶酮类似物
KR20130137624A (ko) * 2010-09-03 2013-12-17 브리스톨-마이어스 스큅 컴퍼니 수용성 항산화제를 사용한 약물 제제
WO2012076973A2 (en) * 2010-12-09 2012-06-14 Aurobindo Pharma Limited Novel salts of dipeptidyl peptidase iv inhibitor

Also Published As

Publication number Publication date
EA029539B8 (ru) 2018-06-29
EA029539B1 (ru) 2018-04-30
WO2012131005A1 (en) 2012-10-04
EA201391371A1 (ru) 2014-02-28
EP2691083A1 (en) 2014-02-05
EP2691083B1 (en) 2017-08-02

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