EA029539B8 - Фармацевтическая композиция ситаглиптина - Google Patents

Фармацевтическая композиция ситаглиптина

Info

Publication number
EA029539B8
EA029539B8 EA201391371A EA201391371A EA029539B8 EA 029539 B8 EA029539 B8 EA 029539B8 EA 201391371 A EA201391371 A EA 201391371A EA 201391371 A EA201391371 A EA 201391371A EA 029539 B8 EA029539 B8 EA 029539B8
Authority
EA
Eurasian Patent Office
Prior art keywords
sitagliptin
pharmaceutical composition
pharmaceutical compositions
compositions
processes
Prior art date
Application number
EA201391371A
Other languages
English (en)
Other versions
EA029539B1 (ru
EA201391371A1 (ru
Inventor
Мая Прескар
Весна Крошель
Сабина Трошт
Луция Хвалец
Ален Кляйиц
Полона Буковец
Original Assignee
Крка, Товарна Здравил, Д.Д., Ново Место
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Крка, Товарна Здравил, Д.Д., Ново Место filed Critical Крка, Товарна Здравил, Д.Д., Ново Место
Publication of EA201391371A1 publication Critical patent/EA201391371A1/ru
Publication of EA029539B1 publication Critical patent/EA029539B1/ru
Publication of EA029539B8 publication Critical patent/EA029539B8/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Abstract

Изобретение относится к стабильным фармацевтическим композициям, содержащим аморфный ситаглиптин, а также к способам получения этих композиций. Фармацевтические композиции получают из раствора, содержащего ситаглиптин и ингибитор кристаллизации.
EA201391371A 2011-03-29 2012-03-29 Фармацевтическая композиция ситаглиптина EA029539B8 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI201100115 2011-03-29
PCT/EP2012/055736 WO2012131005A1 (en) 2011-03-29 2012-03-29 Pharmaceutical composition of sitagliptin

Publications (3)

Publication Number Publication Date
EA201391371A1 EA201391371A1 (ru) 2014-02-28
EA029539B1 EA029539B1 (ru) 2018-04-30
EA029539B8 true EA029539B8 (ru) 2018-06-29

Family

ID=45922684

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391371A EA029539B8 (ru) 2011-03-29 2012-03-29 Фармацевтическая композиция ситаглиптина

Country Status (4)

Country Link
EP (1) EP2691083B1 (ru)
EA (1) EA029539B8 (ru)
SI (1) SI2691083T1 (ru)
WO (1) WO2012131005A1 (ru)

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US20140350023A1 (en) * 2011-12-08 2014-11-27 Ranbaxy Laboratories Limited Amorphous form of sitagliptin salts
WO2015114657A2 (en) * 2014-01-21 2015-08-06 Cadila Healthcare Limited Amorphous form of sitagliptin free base
PL3102187T3 (pl) * 2014-02-03 2020-10-19 Galenicum Health S.L. Stabilne kompozycje farmaceutyczne zawierające sitagliptynę w postaci tabletek o natychmiastowym uwalnianiu
IN2014MU00651A (ru) * 2014-02-25 2015-10-23 Cadila Healthcare Ltd
CN108144065B (zh) * 2016-12-06 2023-05-16 江苏恒瑞医药股份有限公司 一种dpp-4抑制剂的药物组合物
MX2016016260A (es) 2016-12-08 2018-06-07 Alparis Sa De Cv Nuevas formas solidas de sitagliptina.
CN111511365A (zh) * 2017-11-10 2020-08-07 分散技术有限责任公司 改进的药物制剂
WO2021076066A1 (en) 2019-10-14 2021-04-22 Santa Farma İlaç Sanayi̇ A.Ş. Oral formulations comprising sitagliptin hci monohydrate with improved pharmaceutical characteristics
EP3811930A1 (en) * 2019-10-24 2021-04-28 Authenda Pharmaceuticals AG Oral gliptin compositions and method for preparation thereof
GR1010089B (el) 2020-09-15 2021-09-27 Φαρματεν Α.Β.Ε.Ε. Στερεη φαρμακοτεχνικη μορφη περιεχουσα σιταγλιπτινη και μεθοδος παρασκευης αυτης
CN116459227A (zh) * 2023-05-11 2023-07-21 宙晟智维生命科学(上海)有限公司 一种西格列汀片及其制备方法

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US20070172525A1 (en) * 2007-03-15 2007-07-26 Ramesh Sesha Anti-diabetic combinations
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US20080064701A1 (en) * 2007-04-24 2008-03-13 Ramesh Sesha Anti-diabetic combinations
WO2009111200A1 (en) * 2008-03-04 2009-09-11 Merck & Co., Inc. Pharmaceutical compositions of a combination of metformin and a dipeptidyl peptidase-iv inhibitor
US20100249140A1 (en) * 2009-03-30 2010-09-30 Teva Pharmaceutical Industries Ltd. Solid state forms of sitagliptin salts
WO2011127106A1 (en) * 2010-04-08 2011-10-13 Bristol-Myers Squibb Company Pyrimidinylpiperidinyloxypyridinone analogues as gpr119 modulators
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JO2625B1 (en) 2003-06-24 2011-11-01 ميرك شارب اند دوم كوربوريشن Phosphoric acid salts of dipeptidyl betidase inhibitor 4
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WO2005072530A1 (en) 2004-01-16 2005-08-11 Merck & Co., Inc. Novel crystalline salts of a dipeptidyl peptidase-iv inhibitor
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WO2006033848A1 (en) * 2004-09-15 2006-03-30 Merck & Co., Inc. Amorphous form of a phosphoric acid salt of a dipeptidyl peptidase-iv inhibitor
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US20080064701A1 (en) * 2007-04-24 2008-03-13 Ramesh Sesha Anti-diabetic combinations
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US20100249140A1 (en) * 2009-03-30 2010-09-30 Teva Pharmaceutical Industries Ltd. Solid state forms of sitagliptin salts
WO2011127106A1 (en) * 2010-04-08 2011-10-13 Bristol-Myers Squibb Company Pyrimidinylpiperidinyloxypyridinone analogues as gpr119 modulators
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Also Published As

Publication number Publication date
EP2691083A1 (en) 2014-02-05
WO2012131005A1 (en) 2012-10-04
SI2691083T1 (sl) 2017-12-29
EA029539B1 (ru) 2018-04-30
EA201391371A1 (ru) 2014-02-28
EP2691083B1 (en) 2017-08-02

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Designated state(s): AM AZ BY KZ KG MD TJ TM