SI2412828T1 - Mutacije k-ras in b-raf ter terapija s protitelesom anti-egfr - Google Patents

Mutacije k-ras in b-raf ter terapija s protitelesom anti-egfr

Info

Publication number
SI2412828T1
SI2412828T1 SI200831031T SI200831031T SI2412828T1 SI 2412828 T1 SI2412828 T1 SI 2412828T1 SI 200831031 T SI200831031 T SI 200831031T SI 200831031 T SI200831031 T SI 200831031T SI 2412828 T1 SI2412828 T1 SI 2412828T1
Authority
SI
Slovenia
Prior art keywords
ras
egfr antibody
antibody therapy
raf mutations
raf
Prior art date
Application number
SI200831031T
Other languages
English (en)
Inventor
Salvatore Siena
Alberto Bardelli
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39666021&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2412828(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of SI2412828T1 publication Critical patent/SI2412828T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200831031T 2007-03-13 2008-03-11 Mutacije k-ras in b-raf ter terapija s protitelesom anti-egfr SI2412828T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90697607P 2007-03-13 2007-03-13
EP11184356.1A EP2412828B1 (en) 2007-03-13 2008-03-11 K-ras and B-raf mutations and anti-EGFr antibody therapy

Publications (1)

Publication Number Publication Date
SI2412828T1 true SI2412828T1 (sl) 2013-10-30

Family

ID=39666021

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831031T SI2412828T1 (sl) 2007-03-13 2008-03-11 Mutacije k-ras in b-raf ter terapija s protitelesom anti-egfr

Country Status (20)

Country Link
US (2) US20090075267A1 (sl)
EP (2) EP2118322A2 (sl)
JP (3) JP2010521154A (sl)
AR (1) AR065686A1 (sl)
AU (1) AU2008226808B2 (sl)
CA (1) CA2680330A1 (sl)
CL (1) CL2008000716A1 (sl)
CY (1) CY1114159T1 (sl)
DK (1) DK2412828T3 (sl)
ES (1) ES2426814T3 (sl)
HK (1) HK1167005A1 (sl)
HR (1) HRP20130764T1 (sl)
MX (1) MX2009009779A (sl)
PE (1) PE20090690A1 (sl)
PL (1) PL2412828T3 (sl)
PT (1) PT2412828E (sl)
RS (1) RS52932B (sl)
SI (1) SI2412828T1 (sl)
TW (1) TW200904828A (sl)
WO (1) WO2008112274A2 (sl)

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CA2680326A1 (en) * 2007-03-13 2008-09-18 Amgen Inc. K-ras mutations and anti-egfr antibody therapy
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EP3216874A1 (en) 2008-09-05 2017-09-13 TOMA Biosciences, Inc. Methods for stratifying and annotating cancer drug treatment options
IT1391619B1 (it) 2008-11-04 2012-01-11 Silicon Biosystems Spa Metodo per l'individuazione, selezione e analisi di cellule tumorali
US10895575B2 (en) 2008-11-04 2021-01-19 Menarini Silicon Biosystems S.P.A. Method for identification, selection and analysis of tumour cells
EP3181705A1 (en) 2008-11-12 2017-06-21 Caris Life Sciences Switzerland Holdings GmbH Methods and systems of using exosomes for determining phenotypes
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
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WO2011109584A2 (en) * 2010-03-03 2011-09-09 OSI Pharmaceuticals, LLC Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
JP2013523178A (ja) * 2010-04-12 2013-06-17 レスポンス ジェネティクス，インコーポレイティド Ｋｒａｓプライマーおよびプローブ
EP2582837A1 (en) 2010-06-15 2013-04-24 Alberto Bardelli Mlk4 gene, a new diagnostic and prognostic marker in cancers
KR20130113447A (ko) 2010-09-24 2013-10-15 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 고정된 프라이머들을 이용하여 표적 dna의 직접적인 캡쳐, 증폭 및 서열화
WO2012049279A1 (en) 2010-10-14 2012-04-19 Universitaet Des Saarlandes MEANS AND METHODS APPLYING SINGLE NUCLEOTIDE PRIMER EXTENSION WITH ION PAIR-, REVERSED-PHASE HPLC (SIRPH) FOR THE DIAGNOSIS OF SNPs
US8628773B2 (en) 2011-04-07 2014-01-14 Amgen Inc. Antigen binding proteins
ITTO20110990A1 (it) 2011-10-28 2013-04-29 Silicon Biosystems Spa Metodo ed apparato per l'analisi ottica di particelle a basse temperature
US9023640B2 (en) * 2011-12-13 2015-05-05 Fundamental Solutions Corporation Device for rapid detection of infectious agents
KR20220165811A (ko) 2012-08-17 2022-12-15 에프. 호프만-라 로슈 아게 코비메티닙 및 베무라피닙을 투여함을 포함하는 흑색종의 조합 치료법
CA2886397A1 (en) * 2012-09-26 2014-04-03 Insight Genetics, Inc. Methods and compositions relating to next generation sequencing for genetic testing in alk related cancers
EP2977464A4 (en) * 2013-03-19 2016-10-19 Toppan Printing Co Ltd PROCEDURE FOR PREDICTING SENSITIVITY TO EGFR HEMMER
JP6512828B2 (ja) 2014-01-07 2019-05-15 三星電子株式会社Ｓａｍｓｕｎｇ Ｅｌｅｃｔｒｏｎｉｃｓ Ｃｏ．，Ｌｔｄ． ｃ−Ｍｅｔ阻害剤の効能予測または効能検証のためのバイオマーカー
EP3805404A1 (en) * 2014-05-13 2021-04-14 Board of Regents, The University of Texas System Gene mutations and copy number alterations of egfr, kras and met
KR20160037666A (ko) 2014-09-29 2016-04-06 삼성전자주식회사 KRAS 또는 BRAF의 변이를 이용한 c-Met 저해제의 효능 예측
US10471183B2 (en) 2015-12-22 2019-11-12 Access Vascular, Inc. High strength biomedical materials
EP3641842A4 (en) 2017-06-21 2021-03-17 Access Vascular, Inc. HIGH STRENGTH POROUS MATERIALS WITH WATER-SOLUBLE POLYMERS
CN107918013A (zh) * 2017-09-25 2018-04-17 浙江天科高新技术发展有限公司 化学发光酶免测定循环肿瘤细胞中K‑Ras蛋白的方法及试剂盒
CN108085390A (zh) * 2017-12-29 2018-05-29 上海桐树生物科技有限公司 肿瘤驱动基因变异的检测剂、检测试剂盒及其应用
JP2023533506A (ja) 2020-06-30 2023-08-03 アクセス・バスキュラー・インコーポレイテッド マーキングを含む物品および関連する方法

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Also Published As

Publication number Publication date
WO2008112274A3 (en) 2008-12-18
JP2010521154A (ja) 2010-06-24
US20090075267A1 (en) 2009-03-19
CL2008000716A1 (es) 2008-09-22
CA2680330A1 (en) 2008-09-18
HK1167005A1 (en) 2012-11-16
PE20090690A1 (es) 2009-06-22
AU2008226808A1 (en) 2008-09-18
HRP20130764T1 (hr) 2013-10-25
PL2412828T3 (pl) 2013-11-29
WO2008112274A2 (en) 2008-09-18
RS52932B (en) 2014-02-28
TW200904828A (en) 2009-02-01
MX2009009779A (es) 2009-09-23
PT2412828E (pt) 2013-08-02
EP2412828A1 (en) 2012-02-01
EP2118322A2 (en) 2009-11-18
US20110212456A1 (en) 2011-09-01
JP5905422B2 (ja) 2016-04-20
ES2426814T3 (es) 2013-10-25
EP2412828B1 (en) 2013-06-05
CY1114159T1 (el) 2016-08-31
JP2013253105A (ja) 2013-12-19
AU2008226808B2 (en) 2013-04-18
JP2015119726A (ja) 2015-07-02
DK2412828T3 (da) 2013-09-02
AR065686A1 (es) 2009-06-24

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