SI1603598T1 - Radiooznačeni konjugati na osnovi substance P innjihove uporabe - Google Patents

Radiooznačeni konjugati na osnovi substance P innjihove uporabe

Info

Publication number
SI1603598T1
SI1603598T1 SI200430981T SI200430981T SI1603598T1 SI 1603598 T1 SI1603598 T1 SI 1603598T1 SI 200430981 T SI200430981 T SI 200430981T SI 200430981 T SI200430981 T SI 200430981T SI 1603598 T1 SI1603598 T1 SI 1603598T1
Authority
SI
Slovenia
Prior art keywords
substance
dodecane
conjugates based
tetraazacyclo
chelator
Prior art date
Application number
SI200430981T
Other languages
English (en)
Inventor
Adrian Merlo
Helmut Macke
Jean-Claude Reubi
Stephan Good
Original Assignee
Universitaetsspital Basel
Univ Bern
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaetsspital Basel, Univ Bern filed Critical Universitaetsspital Basel
Publication of SI1603598T1 publication Critical patent/SI1603598T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SI200430981T 2003-03-19 2004-03-18 Radiooznačeni konjugati na osnovi substance P innjihove uporabe SI1603598T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03006061 2003-03-19
PCT/EP2004/050329 WO2004082722A2 (en) 2003-03-19 2004-03-18 Radiolabeled conjugates based on substance p and the uses thereof
EP04721547A EP1603598B1 (en) 2003-03-19 2004-03-18 Radiolabeled conjugates based on substance p and the uses thereof

Publications (1)

Publication Number Publication Date
SI1603598T1 true SI1603598T1 (sl) 2009-02-28

Family

ID=33016829

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200430981T SI1603598T1 (sl) 2003-03-19 2004-03-18 Radiooznačeni konjugati na osnovi substance P innjihove uporabe

Country Status (13)

Country Link
US (1) US20070053837A1 (sl)
EP (1) EP1603598B1 (sl)
JP (1) JP2007527366A (sl)
AT (1) ATE410191T1 (sl)
AU (1) AU2004222531A1 (sl)
CA (1) CA2519315A1 (sl)
DE (1) DE602004016968D1 (sl)
DK (1) DK1603598T3 (sl)
ES (1) ES2312983T3 (sl)
HK (1) HK1081884A1 (sl)
NZ (1) NZ542371A (sl)
SI (1) SI1603598T1 (sl)
WO (1) WO2004082722A2 (sl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0717135B8 (pt) 2006-10-16 2021-05-25 Salk Inst Biological Studies antagonista peptídico cíclico de somastotatina e composição farmacêutica
US8691761B2 (en) 2006-10-16 2014-04-08 Jean E. F. Rivier Somatostatin receptor 2 antagonists
GB0624587D0 (en) * 2006-12-08 2007-01-17 Univ Muenchen Tech Chelating agent
JP2012522057A (ja) * 2009-03-30 2012-09-20 ジヨンソン・アンド・ジヨンソン・コンシユーマー・カンパニーズ・インコーポレーテツド 化粧用剤の送達のためのペプチドに基づく系
WO2016025322A1 (en) * 2014-08-09 2016-02-18 Purdue Research Foundation Design and development of neurokinin-1 receptor-binding agent delivery conjugates
JP6989529B2 (ja) 2016-02-09 2022-01-05 シーディーアールディー ベンチャーズ インコーポレイテッド ソマトスタチン受容体アンタゴニスト化合物及びその使用方法
MX2019007615A (es) * 2016-12-23 2019-11-05 Univ Johns Hopkins Imagenología de celulas tumorales e inmunitarias basadas en expresion de pd-l1.
GB201705258D0 (en) * 2017-03-31 2017-05-17 South African Nuclear Energy Corp Ltd Imaging agent
CN117603148A (zh) 2017-05-05 2024-02-27 探针技术开发及商业化中心 双官能螯合物的药代动力学增强及其用途
RU2019139434A (ru) 2017-05-05 2021-06-07 Сентр фор Проуб Девелопмент энд Коммерсиализэйшн Моноклональные антитела против igf-1r и их применение
US10093741B1 (en) 2017-05-05 2018-10-09 Fusion Pharmaceuticals Inc. IGF-1R monoclonal antibodies and uses thereof
CN113853220A (zh) * 2019-03-11 2021-12-28 生物相容英国有限公司 用于中枢神经***肿瘤治疗的放射性微球

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750646A (en) * 1987-09-24 1998-05-12 The Administrators Of The Tulane Educational Fund Bradykinin analogs with non-peptide bond
WO2001002021A2 (en) * 1999-07-05 2001-01-11 Pedro Ortiz Armua A radiolabeled mammalian tachykinin peptide analogue
DE60104421T2 (de) * 2000-05-12 2005-09-22 University Hospital Prochelators von radiometall markierten molekülen
EP1283216A1 (en) * 2001-08-10 2003-02-12 Mallinckrodt Inc. Somatostatin analogues binding to all somatostatin receptor subtypes and their use
CA2500295A1 (en) * 2002-10-02 2004-04-29 Zealand Pharma A/S Stabilized exendin-4 compounds

Also Published As

Publication number Publication date
ES2312983T3 (es) 2009-03-01
US20070053837A1 (en) 2007-03-08
ATE410191T1 (de) 2008-10-15
AU2004222531A1 (en) 2004-09-30
NZ542371A (en) 2008-10-31
WO2004082722A3 (en) 2005-01-06
DK1603598T3 (da) 2009-01-26
EP1603598B1 (en) 2008-10-08
CA2519315A1 (en) 2004-09-30
HK1081884A1 (en) 2006-05-26
DE602004016968D1 (de) 2008-11-20
JP2007527366A (ja) 2007-09-27
EP1603598A2 (en) 2005-12-14
WO2004082722A2 (en) 2004-09-30

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