SI1509529T1 - Estri na poziciji 20 kamptotecina - Google Patents
Estri na poziciji 20 kamptotecinaInfo
- Publication number
- SI1509529T1 SI1509529T1 SI200331685T SI200331685T SI1509529T1 SI 1509529 T1 SI1509529 T1 SI 1509529T1 SI 200331685 T SI200331685 T SI 200331685T SI 200331685 T SI200331685 T SI 200331685T SI 1509529 T1 SI1509529 T1 SI 1509529T1
- Authority
- SI
- Slovenia
- Prior art keywords
- camptothecins
- esters
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2002RM000306A ITRM20020306A1 (it) | 2002-05-31 | 2002-05-31 | Esteri in posizione 20 di camptotecine. |
PCT/IT2003/000329 WO2003101996A2 (en) | 2002-05-31 | 2003-05-28 | Esters in position 20 of camptothecins |
EP03730481A EP1509529B1 (en) | 2002-05-31 | 2003-05-28 | Esters in position 20 of camptothecins |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1509529T1 true SI1509529T1 (sl) | 2009-12-31 |
Family
ID=11456339
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331685T SI1509529T1 (sl) | 2002-05-31 | 2003-05-28 | Estri na poziciji 20 kamptotecina |
SI200332302T SI2112154T1 (sl) | 2002-05-31 | 2003-05-28 | Estri v poloĹľaju 20 kamptotecinov |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200332302T SI2112154T1 (sl) | 2002-05-31 | 2003-05-28 | Estri v poloĹľaju 20 kamptotecinov |
Country Status (22)
Country | Link |
---|---|
US (2) | US7452900B2 (sl) |
EP (2) | EP2112154B1 (sl) |
JP (1) | JP4593270B2 (sl) |
KR (1) | KR101000963B1 (sl) |
CN (1) | CN100376583C (sl) |
AR (1) | AR040140A1 (sl) |
AT (1) | ATE439362T1 (sl) |
AU (1) | AU2003241161C1 (sl) |
CA (1) | CA2487252C (sl) |
CY (2) | CY1109581T1 (sl) |
DE (1) | DE60328777D1 (sl) |
DK (2) | DK2112154T3 (sl) |
ES (2) | ES2331569T3 (sl) |
HK (1) | HK1079206A1 (sl) |
IT (1) | ITRM20020306A1 (sl) |
MX (1) | MXPA04011681A (sl) |
PE (1) | PE20040533A1 (sl) |
PL (1) | PL374009A1 (sl) |
PT (2) | PT1509529E (sl) |
SI (2) | SI1509529T1 (sl) |
TW (1) | TWI331151B (sl) |
WO (1) | WO2003101996A2 (sl) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2852606A1 (fr) * | 2003-03-18 | 2004-09-24 | Inst Nat Sante Rech Med | Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie |
CA2562904C (en) | 2004-04-27 | 2013-07-02 | Wellstat Biologics Corporation | Cancer treatment using viruses and camptothecins |
ITRM20040242A1 (it) * | 2004-05-13 | 2004-08-13 | Ist Naz Stud Cura Dei Tumori | "7-t-butossiimminometilcamptotecina coniugata in posizione 20 con antagonisti delle integrine. |
JP5190958B2 (ja) | 2005-07-14 | 2013-04-24 | ウェルスタット バイオロジクス コーポレイション | ウイルス、フルオロピリミジンおよびカンプトテシンを使用した癌の処置 |
CN103864811A (zh) * | 2012-12-13 | 2014-06-18 | 天津科技大学 | 一种新颖的10-羟基喜树碱20位衍生物制备方法及其在抗肿瘤药物中的应用 |
WO2014121033A1 (en) * | 2013-02-04 | 2014-08-07 | Fl Therapeutics Llc | Soluble complexes of drug analogs and albumin |
WO2015200837A1 (en) | 2014-06-27 | 2015-12-30 | Fl Therapeutics Llc | Abiraterone derivatives and non-covalent complexes with albumin |
US10201617B2 (en) | 2014-10-24 | 2019-02-12 | Zhuhai Beihai Biotech Co., Ltd. | 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin |
CN108135917B (zh) | 2015-09-25 | 2021-07-09 | Zy医疗 | 基于包含多糖-维生素缀合物的颗粒的药物制剂 |
CN106279286B (zh) * | 2016-08-12 | 2018-11-30 | 华中科技大学 | 一种喜树碱膦酸酯类化合物、其制备方法及应用 |
CN110577551A (zh) * | 2018-06-08 | 2019-12-17 | 遵义医学院 | 喜树碱-甘氨酸-5,6-二溴去甲斑蝥素结合物及其应用 |
US20220242874A1 (en) | 2019-07-11 | 2022-08-04 | Sun Pharma Advanced Research Company Limited | Camptothecin derivatives |
CN116514829A (zh) * | 2020-08-21 | 2023-08-01 | 诺茗(北京)生物医药有限公司 | 一种水溶性抗肿瘤前药及其药物组合物和用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4943579A (en) * | 1987-10-06 | 1990-07-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Water soluble prodrugs of camptothecin |
US5004758A (en) * | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
JP3186166B2 (ja) * | 1992-02-10 | 2001-07-11 | ロンザ リミテッド | サリチロイル−カルニチンおよびその製造方法 |
US5646159A (en) * | 1994-07-20 | 1997-07-08 | Research Triangle Institute | Water-soluble esters of camptothecin compounds |
JP3751025B2 (ja) | 1995-12-15 | 2006-03-01 | ザ デクスター コーポレイション | 研摩性不織繊維ウェブ材料及びその製造方法 |
WO2000006134A2 (en) | 1998-07-30 | 2000-02-10 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of l-carnitine and its alkanoyl derivatives in the preparation of medicaments with anticancer activity |
US6204257B1 (en) | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
DK1044977T3 (da) | 1999-03-09 | 2002-07-08 | Sigma Tau Ind Farmaceuti | Camptothecinderivater med antitumoraktivitet |
DE19916945C1 (de) | 1999-04-15 | 2000-10-05 | Clariant Gmbh | Aromatische Aldehydharze und ihre Verwendung als Emulsionsspalter |
US6228855B1 (en) | 1999-08-03 | 2001-05-08 | The Stehlin Foundation For Cancer Research | Aromatic esters of camptothecins and methods to treat cancers |
US6288072B1 (en) | 1999-12-29 | 2001-09-11 | Monroe E. Wall | Camptothecin β-alanine esters with topoisomerase I inhibition |
US6629995B1 (en) | 2000-03-31 | 2003-10-07 | Super Gen, Inc. | Camptothecin conjugates |
-
2002
- 2002-05-31 IT IT2002RM000306A patent/ITRM20020306A1/it unknown
-
2003
- 2003-05-26 TW TW092114165A patent/TWI331151B/zh not_active IP Right Cessation
- 2003-05-28 EP EP09162737.2A patent/EP2112154B1/en not_active Expired - Lifetime
- 2003-05-28 DK DK09162737.2T patent/DK2112154T3/da active
- 2003-05-28 DE DE60328777T patent/DE60328777D1/de not_active Expired - Lifetime
- 2003-05-28 SI SI200331685T patent/SI1509529T1/sl unknown
- 2003-05-28 AT AT03730481T patent/ATE439362T1/de active
- 2003-05-28 AU AU2003241161A patent/AU2003241161C1/en not_active Ceased
- 2003-05-28 US US10/512,094 patent/US7452900B2/en not_active Expired - Fee Related
- 2003-05-28 MX MXPA04011681A patent/MXPA04011681A/es active IP Right Grant
- 2003-05-28 ES ES03730481T patent/ES2331569T3/es not_active Expired - Lifetime
- 2003-05-28 EP EP03730481A patent/EP1509529B1/en not_active Expired - Lifetime
- 2003-05-28 JP JP2004509687A patent/JP4593270B2/ja not_active Expired - Fee Related
- 2003-05-28 CN CNB038125447A patent/CN100376583C/zh not_active Expired - Fee Related
- 2003-05-28 KR KR1020047016881A patent/KR101000963B1/ko not_active IP Right Cessation
- 2003-05-28 PL PL03374009A patent/PL374009A1/xx unknown
- 2003-05-28 SI SI200332302T patent/SI2112154T1/sl unknown
- 2003-05-28 DK DK03730481T patent/DK1509529T3/da active
- 2003-05-28 PT PT03730481T patent/PT1509529E/pt unknown
- 2003-05-28 ES ES09162737T patent/ES2432379T3/es not_active Expired - Lifetime
- 2003-05-28 CA CA2487252A patent/CA2487252C/en not_active Expired - Fee Related
- 2003-05-28 PT PT91627372T patent/PT2112154E/pt unknown
- 2003-05-28 WO PCT/IT2003/000329 patent/WO2003101996A2/en active Application Filing
- 2003-05-30 PE PE2003000528A patent/PE20040533A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101916A patent/AR040140A1/es not_active Application Discontinuation
-
2005
- 2005-12-12 HK HK05111354A patent/HK1079206A1/xx not_active IP Right Cessation
-
2007
- 2007-04-10 US US11/783,495 patent/US7498340B2/en not_active Expired - Fee Related
-
2009
- 2009-11-04 CY CY20091101143T patent/CY1109581T1/el unknown
-
2013
- 2013-09-24 CY CY20131100832T patent/CY1114692T1/el unknown
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