SI1495330T1 - Postopki identificiranja spojin, ki medsebojno vplivajo na transmembranske proteine - Google Patents
Postopki identificiranja spojin, ki medsebojno vplivajo na transmembranske proteineInfo
- Publication number
- SI1495330T1 SI1495330T1 SI200331562T SI200331562T SI1495330T1 SI 1495330 T1 SI1495330 T1 SI 1495330T1 SI 200331562 T SI200331562 T SI 200331562T SI 200331562 T SI200331562 T SI 200331562T SI 1495330 T1 SI1495330 T1 SI 1495330T1
- Authority
- SI
- Slovenia
- Prior art keywords
- cell
- transmembrane protein
- protein
- distribution
- detectable moiety
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5035—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on sub-cellular localization
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5058—Neurological cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37170402P | 2002-04-12 | 2002-04-12 | |
US37941902P | 2002-05-13 | 2002-05-13 | |
US38757002P | 2002-06-12 | 2002-06-12 | |
US42289102P | 2002-11-01 | 2002-11-01 | |
US44255603P | 2003-01-27 | 2003-01-27 | |
PCT/CA2003/000542 WO2003087836A1 (en) | 2002-04-12 | 2003-04-11 | Method of identifying transmembrane protein-interacting compounds |
EP03711772A EP1495330B1 (en) | 2002-04-12 | 2003-04-11 | Method of identifying transmembrane protein-interacting compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1495330T1 true SI1495330T1 (sl) | 2009-06-30 |
Family
ID=29255685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331562T SI1495330T1 (sl) | 2002-04-12 | 2003-04-11 | Postopki identificiranja spojin, ki medsebojno vplivajo na transmembranske proteine |
Country Status (17)
Country | Link |
---|---|
US (8) | US7309576B2 (sl) |
EP (3) | EP2339347A1 (sl) |
JP (4) | JP4542342B2 (sl) |
CN (1) | CN100399028C (sl) |
AT (1) | ATE421697T1 (sl) |
AU (2) | AU2003218586B2 (sl) |
CA (1) | CA2521946C (sl) |
CY (1) | CY1108997T1 (sl) |
DE (1) | DE60325953D1 (sl) |
DK (1) | DK1495330T3 (sl) |
ES (2) | ES2566487T3 (sl) |
HK (2) | HK1128957A1 (sl) |
MX (1) | MXPA04011134A (sl) |
NZ (2) | NZ536063A (sl) |
PT (1) | PT1495330E (sl) |
SI (1) | SI1495330T1 (sl) |
WO (1) | WO2003087836A1 (sl) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1495330T1 (sl) * | 2002-04-12 | 2009-06-30 | Dowd Brian F O | Postopki identificiranja spojin, ki medsebojno vplivajo na transmembranske proteine |
EP2255832A3 (en) * | 2004-06-16 | 2011-02-09 | Affinergy, Inc. | IFBM's to promote attachment of target analytes |
CN1944647B (zh) * | 2006-08-23 | 2010-05-12 | 华东师范大学 | 多巴胺受体新亚型d5b基因及编码的蛋白与应用 |
JP4929462B2 (ja) | 2007-01-29 | 2012-05-09 | 国立大学法人高知大学 | 細胞膜上分子と相互作用する化合物の検出方法 |
US20090117034A1 (en) | 2007-06-15 | 2009-05-07 | Nanhai Chen | Microorganisms for imaging and/or treatment of tumors |
JP5230397B2 (ja) * | 2008-12-18 | 2013-07-10 | 独立行政法人科学技術振興機構 | 抗膜貫通型タンパク質抗体の抗原結合部位を決定する方法 |
CN102580091B (zh) * | 2011-01-12 | 2014-12-10 | 中国科学院上海生命科学研究院 | 增强阿片镇痛剂的镇痛作用的方法及试剂 |
US8643360B1 (en) * | 2012-09-02 | 2014-02-04 | George S. Cargill, III | In-water voltage gradient detector |
TWI472617B (zh) * | 2012-09-17 | 2015-02-11 | Nat Univ Chung Hsing | 調控大分子進入細胞內之蛋白質及其調控大分子進入細胞內之方法 |
US10513711B2 (en) | 2014-08-13 | 2019-12-24 | Dupont Us Holding, Llc | Genetic targeting in non-conventional yeast using an RNA-guided endonuclease |
CN107406838A (zh) | 2014-11-06 | 2017-11-28 | 纳幕尔杜邦公司 | Rna引导的内切核酸酶向细胞中的肽介导的递送 |
WO2016186946A1 (en) | 2015-05-15 | 2016-11-24 | Pioneer Hi-Bred International, Inc. | Rapid characterization of cas endonuclease systems, pam sequences and guide rna elements |
KR102628801B1 (ko) | 2015-10-12 | 2024-01-25 | 이아이디피, 인크. | 세포내 유전자 변형 및 증가된 상동 재조합을 위한 보호 dna 주형 및 이용 방법 |
MX2018004808A (es) | 2015-10-20 | 2018-08-01 | Pioneer Hi Bred Int | Funcion restauradora para un producto genico no funcional mediante sistemas cas guiados y metodos de uso. |
BR112018007796A2 (pt) | 2015-11-06 | 2018-10-30 | Du Pont | plantas de soja, partes de plantas de soja ou sementes de soja, método para selecionar uma célula de soja, métodos de seleção de uma célula de soja e de produção de um locus e molécula de ácido nucleico |
EP3387134B1 (en) | 2015-12-11 | 2020-10-14 | Danisco US Inc. | Methods and compositions for enhanced nuclease-mediated genome modification and reduced off-target site effects |
DK3390631T3 (da) | 2015-12-18 | 2020-07-13 | Danisco Us Inc | Fremgangsmåder og sammensætninger til t-rna-baseret guide-rna-ekspression |
BR112018015348A2 (pt) | 2016-01-26 | 2018-12-18 | Pioneer Hi Bred Int | método para obter uma planta de milho ceroso, planta, semente, polinucleotídeo-guia e método para produzir uma planta híbrida de milho ceroso |
WO2017155714A1 (en) | 2016-03-11 | 2017-09-14 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
WO2017155715A1 (en) | 2016-03-11 | 2017-09-14 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
WO2017155717A1 (en) | 2016-03-11 | 2017-09-14 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
EP3469077A1 (en) | 2016-06-14 | 2019-04-17 | Pioneer Hi-Bred International, Inc. | Use of cpf1 endonuclease for plant genome modifications |
WO2017222773A1 (en) | 2016-06-20 | 2017-12-28 | Pioneer Hi-Bred International, Inc. | Novel cas systems and methods of use |
EP3525578A1 (en) | 2016-10-13 | 2019-08-21 | Pioneer Hi-Bred International, Inc. | Generating northern leaf blight resistant maize |
JP7356351B2 (ja) * | 2016-12-12 | 2023-10-04 | エクセラ・バイオサイエンシーズ・インコーポレイテッド | マイクロキャピラリーアレイを使用したスクリーニングのための方法およびシステム |
WO2018129440A1 (en) | 2017-01-09 | 2018-07-12 | University Of Massachusetts | Complexes for gene deletion and editing |
JP7384801B2 (ja) | 2017-12-15 | 2023-11-21 | ダニスコ・ユーエス・インク | Cas9変異体及び使用方法 |
CN108178790B (zh) * | 2018-01-18 | 2021-09-07 | 上海药明康德新药开发有限公司 | 一种将细胞膜分离以便对跨膜蛋白进行dna编码化合物库筛选的方法 |
CA3109984A1 (en) | 2018-10-16 | 2020-04-23 | Pioneer Hi-Bred International, Inc. | Genome edited fine mapping and causal gene identification |
US20200345725A1 (en) | 2019-01-11 | 2020-11-05 | Omeros Corporation | Methods and Compositions for Treating Cancer |
JP2022526982A (ja) | 2019-04-05 | 2022-05-27 | ダニスコ・ユーエス・インク | 線状組換えDNAコンストラクトを使用してバチルス(Bacillus)のゲノムにドナーDNA配列を組み込むための方法及びその組成物 |
WO2020206197A1 (en) | 2019-04-05 | 2020-10-08 | Danisco Us Inc | Methods for polynucleotide integration into the genome of bacillus using dual circular recombinant dna constructs and compositions thereof |
KR102329302B1 (ko) * | 2019-09-30 | 2021-11-22 | 한국과학기술연구원 | 도파민 d1형 수용체의 활성 측정용 적색 형광 단백질 기반 바이오센서 |
WO2023105244A1 (en) | 2021-12-10 | 2023-06-15 | Pig Improvement Company Uk Limited | Editing tmprss2/4 for disease resistance in livestock |
WO2024013514A2 (en) | 2022-07-15 | 2024-01-18 | Pig Improvement Company Uk Limited | Gene edited livestock animals having coronavirus resistance |
WO2024118882A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative multiplex genome engineering in microbial cells using a selection marker swapping system |
WO2024118881A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative muliplex genome engineering in microbial cells using a bidirectional selection marker system |
WO2024118876A1 (en) | 2022-12-01 | 2024-06-06 | Genencor International Bv | Iterative multiplex genome engineering in microbial cells using a recombinant self-excisable selection marker system |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030022277A1 (en) * | 1995-05-05 | 2003-01-30 | Daniel R. Soppet | Human neuropeptide receptor |
US6004808A (en) * | 1996-06-21 | 1999-12-21 | Aurora Biosciences Corporation | Promiscuous G-protein compositions and their use |
US5891646A (en) | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
US6383761B2 (en) * | 1997-07-28 | 2002-05-07 | The Regents Of The University Of California | Methods and compositions for identifying modulators of G-protein-coupled receptors |
CN1227265C (zh) * | 2000-02-09 | 2005-11-16 | 人类基因组科学公司 | 抗ccr5的抗体 |
AU2001284974A1 (en) | 2000-08-16 | 2002-02-25 | The Trustees Of Columbia University In The City Of New York | Quantitative assessment of erbb/her receptors in biological fluids |
SI1495330T1 (sl) * | 2002-04-12 | 2009-06-30 | Dowd Brian F O | Postopki identificiranja spojin, ki medsebojno vplivajo na transmembranske proteine |
-
2003
- 2003-04-11 SI SI200331562T patent/SI1495330T1/sl unknown
- 2003-04-11 AT AT03711772T patent/ATE421697T1/de active
- 2003-04-11 EP EP10181657A patent/EP2339347A1/en not_active Withdrawn
- 2003-04-11 MX MXPA04011134A patent/MXPA04011134A/es active IP Right Grant
- 2003-04-11 EP EP03711772A patent/EP1495330B1/en not_active Expired - Lifetime
- 2003-04-11 WO PCT/CA2003/000542 patent/WO2003087836A1/en active Application Filing
- 2003-04-11 US US10/509,787 patent/US7309576B2/en not_active Expired - Lifetime
- 2003-04-11 PT PT03711772T patent/PT1495330E/pt unknown
- 2003-04-11 DK DK03711772T patent/DK1495330T3/da active
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2005
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2007
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2009
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2010
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2012
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2015
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2017
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2018
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