SI1354204T2 - Hcv antigen antitelo kombinacijska analiza - Google Patents

Hcv antigen antitelo kombinacijska analiza

Info

Publication number
SI1354204T2
SI1354204T2 SI200130682T SI200130682T SI1354204T2 SI 1354204 T2 SI1354204 T2 SI 1354204T2 SI 200130682 T SI200130682 T SI 200130682T SI 200130682 T SI200130682 T SI 200130682T SI 1354204 T2 SI1354204 T2 SI 1354204T2
Authority
SI
Slovenia
Prior art keywords
hcv
antigens
antigen
antibody combination
hcv antigen
Prior art date
Application number
SI200130682T
Other languages
English (en)
Other versions
SI1354204T1 (sl
Inventor
David Y Chien
Phillip Arcangel
Laura Tandeske
Carlos George-Nasciemento
Doris Coit
Angelica Medina-Selby
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27395684&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1354204(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Publication of SI1354204T1 publication Critical patent/SI1354204T1/sl
Publication of SI1354204T2 publication Critical patent/SI1354204T2/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SI200130682T 2000-06-15 2001-06-14 Hcv antigen antitelo kombinacijska analiza SI1354204T2 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21208200P 2000-06-15 2000-06-15
US28081101P 2001-04-02 2001-04-02
US28086701P 2001-04-02 2001-04-02
PCT/US2001/019369 WO2001096875A2 (en) 2000-06-15 2001-06-14 Hcv antigen/antibody combination assay
EP01952160A EP1354204B2 (en) 2000-06-15 2001-06-14 Hcv antigen/antibody combination assay

Publications (2)

Publication Number Publication Date
SI1354204T1 SI1354204T1 (sl) 2007-04-30
SI1354204T2 true SI1354204T2 (sl) 2010-09-30

Family

ID=27395684

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130682T SI1354204T2 (sl) 2000-06-15 2001-06-14 Hcv antigen antitelo kombinacijska analiza

Country Status (23)

Country Link
US (5) US6630298B2 (sl)
EP (2) EP1350105B1 (sl)
JP (3) JP4834279B2 (sl)
CN (3) CN100463922C (sl)
AT (2) ATE348337T1 (sl)
AU (2) AU2001272945A1 (sl)
BG (1) BG66205B1 (sl)
BR (2) BRPI0111731C1 (sl)
CA (2) CA2412035C (sl)
CY (2) CY1107537T1 (sl)
CZ (1) CZ304185B6 (sl)
DE (2) DE60129598T2 (sl)
DK (2) DK1354204T4 (sl)
ES (2) ES2288969T3 (sl)
HK (2) HK1061861A1 (sl)
HU (1) HU228873B1 (sl)
MX (2) MXPA02012401A (sl)
NO (1) NO332275B1 (sl)
PL (1) PL213363B1 (sl)
PT (2) PT1354204E (sl)
SI (1) SI1354204T2 (sl)
SK (1) SK287694B6 (sl)
WO (2) WO2001096870A2 (sl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2162557C (en) * 1993-05-12 2004-09-28 Amy J. Weiner Conserved motif of hepatitis c virus e2/ns1 region
ATE348337T1 (de) * 2000-06-15 2007-01-15 Novartis Vaccines & Diagnostic Hcv-antigen/antikörper-kombinations-assay
US7491808B2 (en) * 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
ATE517184T1 (de) 2000-08-17 2011-08-15 Tripep Ab Hcv ns3/4a kodierende nukleinsäure
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
DE10106295C1 (de) * 2001-02-02 2002-08-22 Gaifar German American Inst Fo Protein mit mehreren Antigen-Epitop-Sequenzen, welches immobilisiert ist
AR033448A1 (es) * 2001-03-28 2003-12-17 Ortho Clinical Diagnostics Inc Prueba de combinacion antigeno-anticuerpo para hepatitis c para una deteccion temprana de la infeccion
WO2003002749A2 (en) * 2001-06-26 2003-01-09 Abbott Laboratories Methods for the simultaneous detection of hcv antigens and hcv antibodies
US7101683B2 (en) 2001-06-26 2006-09-05 Abbott Laboratories Methods for the simultaneous detection of HCV antigens and HCV antibodies
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
US7332269B2 (en) * 2001-11-11 2008-02-19 Ortho-Clinical Diagnostics, Inc. HCV core protein sequences
FR2839555B1 (fr) 2002-05-10 2007-07-27 Bio Rad Pasteur Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux
EP1546414B1 (en) * 2002-09-09 2008-10-08 Novartis Vaccines and Diagnostics, Inc. Hcv assay
US20040152070A1 (en) * 2003-02-04 2004-08-05 Shah Dinesh O. Method of detection of HCV antibodies in combination assay or sole antibody assay
JP4668191B2 (ja) 2003-08-20 2011-04-13 アモールフィックス・ライフ・サイエンシィズ・リミテッド タンパク質立体配座を検出するためのエピトープ保護アッセイおよび方法
ATE542140T1 (de) * 2004-08-27 2012-02-15 Novartis Vaccines & Diagnostic Nichtstrukturelle hcv-proteinmutanten und verwendungsmöglichkeiten dafür
CN101287989B (zh) * 2005-02-02 2016-04-13 菲鹏生物股份有限公司 一种丙型肝炎病毒抗体检测试剂盒及其制备方法
ES2514316T3 (es) 2005-11-22 2014-10-28 Novartis Vaccines And Diagnostics, Inc. Partículas similares a virus (VLPs) de Norovirus y Sapovirus
US7887803B2 (en) 2005-12-02 2011-02-15 Amorfix Life Sciences Methods and compositions to treat misfolded-SOD1 mediated diseases
US7794692B2 (en) * 2005-12-02 2010-09-14 Amorfix Life Sciences Ltd. Methods and compositions for detecting amyotrophic lateral sclerosis
EP2502999A3 (en) 2006-03-03 2013-01-23 Amorfix Life Sciences Ltd. Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
CN1908666B (zh) * 2006-08-14 2010-05-12 武汉大学 一种检测乙肝核心抗体的双夹心法酶联免疫诊断试剂盒及应用
EP2185195A2 (en) 2007-08-16 2010-05-19 Tripep Ab Immunogen platform
US20120046188A1 (en) * 2009-03-30 2012-02-23 bioMerieux, SA Solid Support for HCV Detection
US20100297607A1 (en) * 2009-05-20 2010-11-25 Jian Zheng Reagents For HCV Antigen-Antibody Combination Assays
EP2556151A1 (en) 2010-04-07 2013-02-13 Novartis AG Method for generating a parvovirus b19 virus-like particle
BR112012031860A8 (pt) * 2010-06-17 2016-09-13 Koninklijke Philips Nv Método para detecção de um alvo biológico em um ensaio de afinidade, disposição de detecção para um alvo biológico e porção de captura para uso em um método
EP3153578A1 (en) 2010-07-06 2017-04-12 Novartis Ag Norovirus derived immunogenic compositions and methods
WO2012006500A2 (en) * 2010-07-08 2012-01-12 Abbott Laboratories Monoclonal antibodies against hepatitis c virus core protein
US8691950B2 (en) * 2011-01-13 2014-04-08 Orth-Clinical Diagnostics, Inc. Treponema pallidum triplet antigen
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
EP2968526A4 (en) * 2013-03-14 2016-11-09 Abbott Lab ANTIGEN-ANTIBODY COMBINATION ASSAY OF HEPATITIS C VIRUS AND METHODS AND COMPOSITIONS FOR USE THEREWITH
CN105209616A (zh) 2013-03-14 2015-12-30 雅培制药有限公司 用于改进的抗体检测的hcv ns3重组抗原及其突变体
CN113549148A (zh) 2013-03-14 2021-10-26 雅培制药有限公司 Hcv核心脂质结合结构域单克隆抗体
CN103630690B (zh) * 2013-12-17 2014-08-20 朱之炜 丙型肝炎病毒抗原抗体联合检测试剂盒及其检测方法
JP6859314B2 (ja) 2015-03-27 2021-04-14 オーソ−クリニカル・ダイアグノスティックス・インコーポレイテッドＯｒｔｈｏ−Ｃｌｉｎｉｃａｌ Ｄｉａｇｎｏｓｔｉｃｓ， Ｉｎｃ． Ｈｃｖ ｎｓ４ａ／改変されたｎｓ３ポリペプチド及びその使用
WO2016172121A1 (en) * 2015-04-20 2016-10-27 Qoolabs, Inc. Camelid single-domain hcv antibodies and methods of use
EP4209784A1 (en) * 2017-09-27 2023-07-12 Bio-Rad Laboratories, Inc. Digital affinity linkage assay
CN110261616B (zh) * 2019-04-30 2021-07-20 广东菲鹏生物有限公司 一种丙型肝炎病毒检测试剂盒
CN115838420B (zh) * 2022-10-31 2023-05-05 北京科跃中楷生物技术有限公司 一种可溶性hcv重组蛋白的制备方法及其制备的抗体检测试剂

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) * 1987-11-18 2000-02-23 希龙股份有限公司 非ａ和非ｂ肝炎病毒的诊断及疫苗
US5350671A (en) 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
YU48038B (sh) * 1987-11-18 1996-10-18 Chiron Corp. Postupak za dijagnostiku ne-a, ne-v hepatitisa
JP2730153B2 (ja) 1989-03-16 1998-03-25 日本合成ゴム株式会社 熱可塑性樹脂組成物およびその製造方法
KR0185373B1 (ko) 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
AU638719B2 (en) * 1989-05-18 1993-07-08 Novartis Vaccines And Diagnostics, Inc. Nanbv diagnostics: polynucleotides useful for screening for hepatitis c virus
RU2130969C1 (ru) * 1990-04-04 1999-05-27 Чирон Корпорейшн Композиция для диагностики гепатита c человека (варианты), способ и набор для обнаружения антител к вирусу гепатита c человека
US6312889B1 (en) 1990-04-04 2001-11-06 Chiron Corporation Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
PT97247B (pt) * 1991-04-03 1997-10-31 Chiron Corp Processo de preparacao de combinacoes de antigenios do virus da hepapite c (hcv) para uso em imunoensaios para anticorpos anti-hcv
RO117329B1 (ro) 1991-06-24 2002-01-30 Chiron Corp Emeryville Polipeptide care contin o secventa a virusului hepatitei c
UA39944C2 (uk) 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
BR9405334A (pt) * 1993-04-27 1999-05-25 Innogenetics Nv Novas sequências de genótipos de vírus da hepatite c e seu uso como agentes terapêuticos e diagnóstico
US6001604A (en) * 1993-12-29 1999-12-14 Bio-Technology General Corp. Refolding of proinsulins without addition of reducing agents
JP3217600B2 (ja) 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US5843752A (en) 1995-05-12 1998-12-01 Schering Corporation Soluble active hepatitis C virus protease
US5990276A (en) 1996-05-10 1999-11-23 Schering Corporation Synthetic inhibitors of hepatitis C virus NS3 protease
JP3945822B2 (ja) * 1996-05-24 2007-07-18 カイロン コーポレイション 複数エピトープ融合タンパク質
US6514731B1 (en) * 1996-05-24 2003-02-04 Chiron Corporation Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens
EP0870830A3 (en) * 1997-02-10 2004-02-25 Advanced Life Science Institute, Inc. Chimera hepatitis C virus antigen
WO1999015898A1 (en) * 1997-09-22 1999-04-01 Chiron Corporation Method for detecting antibodies in a sample
BR9906660A (pt) * 1998-07-30 2000-08-29 Advanced Life Science Inst Inc Processo para medir vìrus da hepatite c
ATE348337T1 (de) * 2000-06-15 2007-01-15 Novartis Vaccines & Diagnostic Hcv-antigen/antikörper-kombinations-assay

Also Published As

Publication number Publication date
ES2277932T3 (es) 2007-08-01
HK1061861A1 (en) 2004-10-08
EP1350105A2 (en) 2003-10-08
EP1354204A2 (en) 2003-10-22
DK1354204T3 (da) 2007-04-10
PL365599A1 (en) 2005-01-10
WO2001096875A3 (en) 2003-08-28
BRPI0111682B8 (pt) 2021-07-27
ATE348337T1 (de) 2007-01-15
WO2001096870A3 (en) 2003-07-31
EP1354204B1 (en) 2006-12-13
HU228873B1 (hu) 2013-06-28
CN1256591C (zh) 2006-05-17
JP2011125350A (ja) 2011-06-30
DK1354204T4 (da) 2010-06-14
CZ304185B6 (cs) 2013-12-11
JP4834279B2 (ja) 2011-12-14
US20040063092A1 (en) 2004-04-01
US6630298B2 (en) 2003-10-07
NO20025878D0 (no) 2002-12-06
AU2001272945A1 (en) 2001-12-24
CN1660913A (zh) 2005-08-31
ES2288969T3 (es) 2008-02-01
US20020146685A1 (en) 2002-10-10
ES2277932T5 (es) 2010-06-28
US20020192639A1 (en) 2002-12-19
CA2413003A1 (en) 2001-12-20
AU2001272948A1 (en) 2001-12-24
PT1354204E (pt) 2007-03-30
PL213363B1 (pl) 2013-02-28
CZ20024058A3 (cs) 2003-09-17
EP1354204B2 (en) 2010-04-21
WO2001096875A2 (en) 2001-12-20
DK1350105T3 (da) 2007-11-12
JP2004506878A (ja) 2004-03-04
US6797809B2 (en) 2004-09-28
BRPI0111731C1 (pt) 2021-07-27
JP2004510133A (ja) 2004-04-02
DE60125240T2 (de) 2007-07-12
BRPI0111731B8 (pt) 2016-08-23
HUP0500444A3 (en) 2010-03-29
JP4837229B2 (ja) 2011-12-14
CA2413003C (en) 2013-08-13
BRPI0111731B1 (pt) 2016-07-05
CY1107537T1 (el) 2013-03-13
NO20025878L (no) 2003-02-12
DE60129598T2 (de) 2008-04-17
MXPA02012424A (es) 2003-04-25
ATE368221T1 (de) 2007-08-15
HK1079796A1 (en) 2006-04-13
SK17772002A3 (sk) 2003-10-07
CN100463922C (zh) 2009-02-25
DE60125240T3 (de) 2010-10-28
MXPA02012401A (es) 2003-04-25
US7319144B2 (en) 2008-01-15
CA2412035A1 (en) 2001-12-20
CN1489692A (zh) 2004-04-14
DE60125240D1 (de) 2007-01-25
BG107441A (bg) 2004-01-30
BRPI0111682B1 (pt) 2017-09-19
US20040096822A1 (en) 2004-05-20
BG66205B1 (bg) 2012-01-31
CY1106820T1 (el) 2012-05-23
US7241879B2 (en) 2007-07-10
WO2001096875A9 (en) 2002-08-15
US20040265801A1 (en) 2004-12-30
CN1466682A (zh) 2004-01-07
WO2001096870A2 (en) 2001-12-20
SI1354204T1 (sl) 2007-04-30
CN1214244C (zh) 2005-08-10
PT1350105E (pt) 2007-08-13
NO332275B1 (no) 2012-08-13
US6632601B2 (en) 2003-10-14
EP1350105B1 (en) 2007-07-25
BR0111731A (pt) 2004-02-10
HUP0500444A2 (hu) 2005-08-29
CA2412035C (en) 2012-04-10
SK287694B6 (sk) 2011-06-06
DE60129598D1 (de) 2007-09-06
BR0111682A (pt) 2004-01-06

Similar Documents

Publication Publication Date Title
PL365599A1 (en) Hcv antigen/antibody combination assay
UA41266C2 (uk) Комбінація послідовностей епітопів вірусу гепатиту с (hcv), спосіб виявлення антитіл до вірусу гепатиту с (hcv), набір для виконання аналізу при виявленні антитіл до антигену гепатиту с (hcv)
NO20051715L (no) HCV assay
WO2002090961A3 (en) Systems and methods for detection of analytes in biological fluids
US6723502B2 (en) Hepatitis C antigen—antibody combination assay for the early detection of infection
CA2071016A1 (en) Method for detecting bovine diarrhoea virus infection nucleotide sequence encoding a protein induced by this virus infection and recombinant proteins and antigens relating thereto
WO2003012395A3 (en) Early detection of mycobacterial disease using peptides
EP1310796A3 (en) Reagents for the simultaneous detection of HCV core antigens and antibodies
TW200722527A (en) Methods of detecting hepatitis C virus
DE69830174D1 (de) Antikörper und sonstige bindungsmoleküle gegen hepatitis b virusantigene
JP4283527B2 (ja) Ｈｃｖコア・タンパク質配列
CA2380777A1 (en) Hepatitis c viral antigen immunoassay detection systems
EP0985931A3 (en) Recombinant antigen immunoassay for the diagnosis of syphilis
Ireland Development of enzyme-linked immunosorbent assays for antibodies to hepatitis B virus.
AR037215A1 (es) Reactivos para la deteccion simultanea de anticuerpos y antigenos nucleares del hcv