SI0922703T1 - Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds - Google Patents

Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds

Info

Publication number: SI0922703T1
Authority: SI; Slovenia
Prior art keywords: active compounds; substituted heterocyclic; analgesically active; benzocycloalkenes; heterocyclic benzocycloalkenes
Prior art date: 1997-12-13

Application number

SI9830350T

Other languages

English (en)

Slovenian (sl)

Inventor

Oswald Dr. Zimmer

Wolfgang Prof. Dr. Strassburger

Claudia Dr. P�tz

Werner Dr. Englberger

Babette-Yvonne Dr. K�gel

Original Assignee

Gruenenthal Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-13

Filing date

1998-11-23

Publication date

2003-04-30

1998-11-23 Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh

2003-04-30 Publication of SI0922703T1 publication Critical patent/SI0922703T1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/08—Naphthothiopyrans; Hydrogenated naphthothiopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)

SI9830350T 1997-12-13 1998-11-23 Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds SI0922703T1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19755480A DE19755480A1 (de)	1997-12-13	1997-12-13	Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen
EP98122218A EP0922703B1 (fr)	1997-12-13	1998-11-23	Benzocycloalcènes hétérocycliques substitués et leur application comme composés analgésiquement actifs

Publications (1)

Publication Number	Publication Date
SI0922703T1 true SI0922703T1 (en)	2003-04-30

Family

ID=7851818

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9830350T SI0922703T1 (en)	1997-12-13	1998-11-23	Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds

Country Status (29)

Country	Link
US (1)	US6013809A (fr)
EP (1)	EP0922703B1 (fr)
JP (1)	JPH11246547A (fr)
KR (1)	KR19990062982A (fr)
CN (1)	CN100376564C (fr)
AR (1)	AR017800A1 (fr)
AT (1)	ATE229016T1 (fr)
AU (1)	AU747979B2 (fr)
BR (1)	BR9805437A (fr)
CA (1)	CA2256007C (fr)
CO (1)	CO4990950A1 (fr)
CZ (1)	CZ294990B6 (fr)
DE (2)	DE19755480A1 (fr)
DK (1)	DK0922703T3 (fr)
ES (1)	ES2189072T3 (fr)
HK (1)	HK1020944A1 (fr)
HU (1)	HU226014B1 (fr)
IL (1)	IL127518A (fr)
MY (1)	MY133169A (fr)
NO (1)	NO985818L (fr)
NZ (1)	NZ332622A (fr)
PE (1)	PE133499A1 (fr)
PL (1)	PL194934B1 (fr)
PT (1)	PT922703E (fr)
RU (1)	RU2197484C2 (fr)
SI (1)	SI0922703T1 (fr)
SK (1)	SK283366B6 (fr)
UY (1)	UY25296A1 (fr)
ZA (1)	ZA9811346B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6077850A (en) *	1997-04-21	2000-06-20	G.D. Searle & Co.	Substituted benzopyran analogs for the treatment of inflammation
US6221897B1 (en) *	1998-06-10	2001-04-24	Aventis Pharma Deutschland Gmbh	Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19830105C1 (de) *	1998-07-06	2000-02-17	Gruenenthal Gmbh	Acridinderivate
WO2000010965A2 (fr) *	1998-08-20	2000-03-02	Takeda Chemical Industries, Ltd.	Sels d'ammonium quaternaire et leur utilisation
DE10033459A1 (de) *	2000-07-10	2002-01-24	Gruenenthal Gmbh	Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel
US7289083B1 (en) *	2000-11-30	2007-10-30	Palm, Inc.	Multi-sided display for portable computer
CN102076654B (zh) *	2008-04-28	2014-07-23	詹森药业有限公司	苯并环庚烷及苯并噁庚英衍生物
MX354242B (es)	2011-10-28	2018-02-20	Lumena Pharmaceuticals Inc	Nhibidores de la recirculación de ácidos biliares para el tratamiento de enfermedades hepáticas colestásicas pediátricas.
CN104844471B (zh) *	2015-04-21	2017-05-03	苏州远智医药科技有限公司	一种作为dor受体拮抗剂的化合物
CN109896991B (zh) *	2017-12-08	2020-11-20	苏州远智医药科技有限公司	一种δ阿片受体拮抗剂及其用途和药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3444176A (en) *	1967-04-28	1969-05-13	Mcneilab Inc	Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof
US4104280A (en) *	1977-02-04	1978-08-01	Syntex (U.S.A.) Inc.	Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives
JPS61130286A (ja) *	1984-11-28	1986-06-18	Suntory Ltd	２，３−ジヒドロ−１−ベンズオキセピン誘導体
JP3042156B2 (ja) *	1992-02-20	2000-05-15	田辺製薬株式会社	ナフタレン誘導体、その製法及びその合成中間体
ATE161530T1 (de) *	1992-09-04	1998-01-15	Takeda Chemical Industries Ltd	Kondensierte heterozyklische verbindungen, deren herstellung und verwendung

1997
- 1997-12-13 DE DE19755480A patent/DE19755480A1/de not_active Ceased
1998
- 1998-11-03 MY MYPI98004994A patent/MY133169A/en unknown
- 1998-11-03 NZ NZ332622A patent/NZ332622A/xx unknown
- 1998-11-17 PE PE1998001116A patent/PE133499A1/es not_active Application Discontinuation
- 1998-11-23 DE DE59806523T patent/DE59806523D1/de not_active Expired - Fee Related
- 1998-11-23 EP EP98122218A patent/EP0922703B1/fr not_active Expired - Lifetime
- 1998-11-23 ES ES98122218T patent/ES2189072T3/es not_active Expired - Lifetime
- 1998-11-23 SI SI9830350T patent/SI0922703T1/xx unknown
- 1998-11-23 DK DK98122218T patent/DK0922703T3/da active
- 1998-11-23 PT PT98122218T patent/PT922703E/pt unknown
- 1998-11-23 AT AT98122218T patent/ATE229016T1/de not_active IP Right Cessation
- 1998-12-03 AR ARP980106155A patent/AR017800A1/es unknown
- 1998-12-09 BR BR9805437-6A patent/BR9805437A/pt not_active IP Right Cessation
- 1998-12-10 UY UY25296A patent/UY25296A1/es not_active Application Discontinuation
- 1998-12-10 CZ CZ19984076A patent/CZ294990B6/cs not_active IP Right Cessation
- 1998-12-10 ZA ZA9811346A patent/ZA9811346B/xx unknown
- 1998-12-10 SK SK1699-98A patent/SK283366B6/sk not_active IP Right Cessation
- 1998-12-10 CO CO98073439A patent/CO4990950A1/es unknown
- 1998-12-11 AU AU97073/98A patent/AU747979B2/en not_active Ceased
- 1998-12-11 JP JP10353219A patent/JPH11246547A/ja active Pending
- 1998-12-11 CA CA002256007A patent/CA2256007C/fr not_active Expired - Fee Related
- 1998-12-11 NO NO985818A patent/NO985818L/no not_active Application Discontinuation
- 1998-12-11 CN CNB981253180A patent/CN100376564C/zh not_active Expired - Fee Related
- 1998-12-11 PL PL330257A patent/PL194934B1/pl not_active IP Right Cessation
- 1998-12-11 IL IL12751898A patent/IL127518A/xx not_active IP Right Cessation
- 1998-12-11 US US09/208,990 patent/US6013809A/en not_active Expired - Fee Related
- 1998-12-11 KR KR1019980054315A patent/KR19990062982A/ko not_active Application Discontinuation
- 1998-12-11 HU HU9802886A patent/HU226014B1/hu not_active IP Right Cessation
- 1998-12-15 RU RU98122335/04A patent/RU2197484C2/ru not_active IP Right Cessation
1999
- 1999-11-26 HK HK99105471A patent/HK1020944A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2189072T3 (es)	2003-07-01
ZA9811346B (en)	1999-06-14
NO985818D0 (no)	1998-12-11
BR9805437A (pt)	2000-05-02
HK1020944A1 (en)	2000-05-26
CZ294990B6 (cs)	2005-04-13
EP0922703B1 (fr)	2002-12-04
IL127518A (en)	2003-05-29
IL127518A0 (en)	1999-10-28
DE59806523D1 (de)	2003-01-16
JPH11246547A (ja)	1999-09-14
MY133169A (en)	2007-10-31
CZ407698A3 (cs)	1999-06-16
ATE229016T1 (de)	2002-12-15
PL330257A1 (en)	1999-06-21
NZ332622A (en)	2000-03-27
HU9802886D0 (en)	1999-02-01
PT922703E (pt)	2003-04-30
DK0922703T3 (da)	2003-03-17
AR017800A1 (es)	2001-10-24
HUP9802886A2 (hu)	2001-04-28
AU9707398A (en)	1999-07-01
NO985818L (no)	1999-06-14
KR19990062982A (ko)	1999-07-26
EP0922703A1 (fr)	1999-06-16
SK283366B6 (sk)	2003-06-03
PL194934B1 (pl)	2007-07-31
CN1221743A (zh)	1999-07-07
US6013809A (en)	2000-01-11
RU2197484C2 (ru)	2003-01-27
HUP9802886A3 (en)	2001-09-28
DE19755480A1 (de)	1999-06-24
SK169998A3 (en)	1999-07-12
CN100376564C (zh)	2008-03-26
HU226014B1 (en)	2008-02-28
PE133499A1 (es)	2000-02-02
UY25296A1 (es)	2001-05-31
CA2256007A1 (fr)	1999-06-13
AU747979B2 (en)	2002-05-30
CO4990950A1 (es)	2000-12-26
CA2256007C (fr)	2009-04-14

Publication	Publication Date	Title
HU9702034D0 (en)	1998-01-28	Heterocyclic compounds of leukocita-adhesion-inhibitor and vla-4-antagonist activity
ZA989505B (en)	1999-04-20	Substituted isoquinoline-3-carboxamides their preparation and their use as pharmaceuticals
PL340254A1 (en)	2001-01-29	Derivatives of pleuromutillin as antimicrobial agents
HU9503045D0 (en)	1995-12-28	Heterocyclic compounds and their preparation and use
HRP20060251B1 (hr)	2016-08-12	Supstituirani oksazolidinoni i njihova uporaba
IL126095A0 (en)	1999-05-09	Azolobenzazepine derivatives as neurogically active agents
EP0788489A4 (fr)	2000-11-15	Composes heterocycliques et leur utilisation
ZA988469B (en)	1999-03-17	Pyrrolidin-2-one compounds and their use as neuraminidase inhibitors
HU9800555D0 (en)	1998-05-28	Substituted amino-compounds and their use as analgetic agent
HK1053657A1 (en)	2003-10-31	Novel heterocyclic compounds and salts thereof andmedicinal use of the same
GB9702354D0 (en)	1997-03-26	Compounds and their use
ZA952410B (en)	1995-12-01	Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals
IL139795A0 (en)	2002-02-10	Oxadiazoline derivatives and their use as insecticides
HK1020944A1 (en)	2000-05-26	Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds
HUP0001781A3 (en)	2002-02-28	Substituted pyrazolyl-pyrazole derivatives and their use as herbicides
HK1048318B (zh)	2004-12-10	取代的3-苯基-5-烷氧基-1，3，4-噁二唑-2-酮及其作為脂酶抑制劑的用途
GB9724859D0 (en)	1998-01-21	Compounds and their use as antibacterial agents
EP1137412A4 (fr)	2002-04-03	Composes heterocycliques azotes substitues et leur utilisation therapeutique
IL114490A0 (en)	1995-11-27	Heterocyclic compounds their preparation and their use
HUP0003845A3 (en)	2003-05-28	Use of 8a-azalides as antimicrobial agents
GB9824160D0 (en)	1998-12-30	Heterocyclic compounds and their therapeutic use
EP1032559A4 (fr)	2005-05-25	Derives d'amino-alkylphenols et composes associes
HK1048315A1 (zh)	2003-03-28	取代的雜芳基氧基乙酰苯胺類化合物及其作為除草劑的應用
AU2152497A (en)	1997-10-10	Heterocyclic compounds and their preparation and use
HK1044773A1 (zh)	2002-11-01	雜環n-丙酮基苯甲酰胺以及它們作為殺菌劑的使用