SG44630A1 - Preparation of substituted guanidines - Google Patents
Preparation of substituted guanidinesInfo
- Publication number
- SG44630A1 SG44630A1 SG1996004538A SG1996004538A SG44630A1 SG 44630 A1 SG44630 A1 SG 44630A1 SG 1996004538 A SG1996004538 A SG 1996004538A SG 1996004538 A SG1996004538 A SG 1996004538A SG 44630 A1 SG44630 A1 SG 44630A1
- Authority
- SG
- Singapore
- Prior art keywords
- preparation
- substituted guanidines
- guanidines
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/02—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/854,496 US5298657A (en) | 1992-03-20 | 1992-03-20 | Preparation of substituted guanidines |
Publications (1)
Publication Number | Publication Date |
---|---|
SG44630A1 true SG44630A1 (en) | 1997-12-19 |
Family
ID=25318840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG1996004538A SG44630A1 (en) | 1992-03-20 | 1993-03-17 | Preparation of substituted guanidines |
Country Status (10)
Country | Link |
---|---|
US (2) | US5298657A (fr) |
EP (1) | EP0634997A4 (fr) |
JP (1) | JPH07505159A (fr) |
KR (1) | KR950700875A (fr) |
AU (2) | AU681576B2 (fr) |
CA (1) | CA2130924A1 (fr) |
PH (1) | PH31008A (fr) |
SG (1) | SG44630A1 (fr) |
WO (1) | WO1993019042A1 (fr) |
ZA (1) | ZA931935B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991012797A1 (fr) | 1990-03-02 | 1991-09-05 | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALF SCIENCES UNIVERSITY | Guanidines tri et tetra substitues et leur utilisation en tant qu'antagonistes d'aminoacides excitateurs |
US5262568A (en) * | 1990-03-02 | 1993-11-16 | State Of Oregon | Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists |
US5847006A (en) * | 1991-02-08 | 1998-12-08 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
DE69230220T2 (de) * | 1991-02-08 | 2000-06-21 | Cambridge Neuroscience Res | Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung |
US5741661A (en) * | 1991-02-08 | 1998-04-21 | Cambridge Neuroscience, Inc. | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers |
KR20030097618A (ko) * | 1993-05-27 | 2003-12-31 | 캠브리지 뉴로사이언스, 인코포레이티드 | 치료용 치환 구아니딘류 |
JPH09505591A (ja) * | 1993-11-23 | 1997-06-03 | ケンブリッジ・ニューロサイエンス・インコーポレーテッド | 治療用置換グアニジン類 |
KR100423272B1 (ko) | 1994-02-03 | 2004-09-01 | 캠브리지 뉴로사이언스, 인코포레이티드 | 신경전달물질의방출을조절하는화합물,이의약학적으로허용가능한염및이를포함하는약학조성물 |
US7351743B1 (en) | 1994-02-03 | 2008-04-01 | Wyeth | Therapeutic guanidines |
US6787569B1 (en) | 1994-02-03 | 2004-09-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
US6143791A (en) * | 1994-02-03 | 2000-11-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
US20040258742A1 (en) * | 2003-04-11 | 2004-12-23 | Van Osdol William Woodson | Transdermal administration of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methyl guanidines |
JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス,インコーポレイティド | Pde阻害による神経新生の調節 |
CA2625210A1 (fr) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Modulation de la neurogenese dont la mediation est assuree par recepteur gaba |
US20070244143A1 (en) * | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
JP2009536667A (ja) * | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | 5ht受容体介在性の神経新生 |
AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
KR20090064418A (ko) | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
WO2008036678A2 (fr) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Modulation induite par ppar de la neurogenèse |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2010099217A1 (fr) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine |
CN105175286B (zh) * | 2015-08-17 | 2017-07-28 | 湖南海利化工股份有限公司 | 一种盐酸烷基胍盐的制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1756315A (en) * | 1927-11-28 | 1930-04-29 | Rubber Service Lab Co | Rubber vulcanization process |
US2258321A (en) * | 1939-08-12 | 1941-10-07 | American Cyanamid Co | Condensation products of amines and monoalkylol cyanamides |
US2289541A (en) * | 1941-01-18 | 1942-07-14 | American Cyanamid Co | Insecticide |
US2350453A (en) * | 1942-03-04 | 1944-06-06 | American Cyanamid Co | Method of producing substituted guanidine and biguanide salts |
US3804891A (en) * | 1968-06-17 | 1974-04-16 | American Cyanamid Co | Bis-(phthalic acid)-oxalic acid anhydrides and related compounds |
US3914306A (en) * | 1972-09-22 | 1975-10-21 | Rorer Inc William H | Guanidines |
US4007181A (en) * | 1974-02-11 | 1977-02-08 | The Upjohn Company | Adamantyl containing guanidines |
US4051256A (en) * | 1976-09-19 | 1977-09-27 | Imperial Chemical Industries Limited | Guanidine derivatives |
JPS6221556A (ja) * | 1985-07-22 | 1987-01-29 | Ricoh Co Ltd | イオン流静電記録式の記録装置 |
JPS62215556A (ja) * | 1986-03-17 | 1987-09-22 | Sanwa Chem:Kk | ビグアニド誘導体の製法 |
US4709094A (en) * | 1986-07-10 | 1987-11-24 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Sigma brain receptor ligands and their use |
JP2840278B2 (ja) * | 1989-02-17 | 1998-12-24 | キヤノン株式会社 | 画像処理装置 |
WO1991012797A1 (fr) * | 1990-03-02 | 1991-09-05 | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALF SCIENCES UNIVERSITY | Guanidines tri et tetra substitues et leur utilisation en tant qu'antagonistes d'aminoacides excitateurs |
IN172842B (fr) * | 1990-05-17 | 1993-12-11 | Boots Pharmaceuticals Limited |
-
1992
- 1992-03-20 US US07/854,496 patent/US5298657A/en not_active Expired - Lifetime
-
1993
- 1993-03-17 JP JP5516694A patent/JPH07505159A/ja active Pending
- 1993-03-17 WO PCT/US1993/002424 patent/WO1993019042A1/fr not_active Application Discontinuation
- 1993-03-17 AU AU38115/93A patent/AU681576B2/en not_active Ceased
- 1993-03-17 SG SG1996004538A patent/SG44630A1/en unknown
- 1993-03-17 EP EP93907550A patent/EP0634997A4/fr not_active Ceased
- 1993-03-17 CA CA002130924A patent/CA2130924A1/fr not_active Abandoned
- 1993-03-18 ZA ZA931935A patent/ZA931935B/xx unknown
- 1993-12-08 PH PH47399A patent/PH31008A/en unknown
-
1994
- 1994-02-08 US US08/192,990 patent/US5489709A/en not_active Expired - Lifetime
- 1994-09-16 KR KR1019940703237A patent/KR950700875A/ko not_active Application Discontinuation
-
1997
- 1997-12-02 AU AU46807/97A patent/AU4680797A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU3811593A (en) | 1993-10-21 |
AU4680797A (en) | 1998-03-12 |
EP0634997A1 (fr) | 1995-01-25 |
EP0634997A4 (fr) | 1995-04-26 |
KR950700875A (ko) | 1995-02-20 |
WO1993019042A1 (fr) | 1993-09-30 |
AU681576B2 (en) | 1997-09-04 |
US5489709A (en) | 1996-02-06 |
JPH07505159A (ja) | 1995-06-08 |
ZA931935B (en) | 1993-12-30 |
US5298657A (en) | 1994-03-29 |
CA2130924A1 (fr) | 1993-09-30 |
PH31008A (en) | 1997-12-23 |
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