SG178927A1 - Systems and methods for producing hyperpolarized materials and mixtures thereof - Google Patents

Systems and methods for producing hyperpolarized materials and mixtures thereof

Info

Publication number
SG178927A1
SG178927A1 SG2012014379A SG2012014379A SG178927A1 SG 178927 A1 SG178927 A1 SG 178927A1 SG 2012014379 A SG2012014379 A SG 2012014379A SG 2012014379 A SG2012014379 A SG 2012014379A SG 178927 A1 SG178927 A1 SG 178927A1
Authority
SG
Singapore
Prior art keywords
systems
mixtures
methods
producing hyperpolarized
hyperpolarized materials
Prior art date
Application number
SG2012014379A
Inventor
Neal Kalechofsky
Avrum Belzer
Original Assignee
Millikelvin Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millikelvin Technologies Llc filed Critical Millikelvin Technologies Llc
Publication of SG178927A1 publication Critical patent/SG178927A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent

Abstract

The present disclosure provides various methods and systems for manufacture, transport and delivery of material including highly polarized nuclei that is in a hyperpolarized state.
SG2012014379A 2009-08-31 2010-08-31 Systems and methods for producing hyperpolarized materials and mixtures thereof SG178927A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23864709P 2009-08-31 2009-08-31
PCT/US2010/047310 WO2011026103A2 (en) 2009-08-31 2010-08-31 Systems and methods for producing hyperpolarized materials and mixtures thereof

Publications (1)

Publication Number Publication Date
SG178927A1 true SG178927A1 (en) 2012-04-27

Family

ID=43628703

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012014379A SG178927A1 (en) 2009-08-31 2010-08-31 Systems and methods for producing hyperpolarized materials and mixtures thereof

Country Status (9)

Country Link
EP (1) EP2473198A4 (en)
JP (1) JP5792726B2 (en)
KR (1) KR20120101339A (en)
CN (1) CN102753201A (en)
AU (1) AU2010286413B2 (en)
CA (1) CA2772190A1 (en)
IN (1) IN2012DN02418A (en)
SG (1) SG178927A1 (en)
WO (1) WO2011026103A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8703102B2 (en) 2008-04-04 2014-04-22 Millikelvin Technologies Llc Systems and methods for producing hyperpolarized materials and mixtures thereof
KR101095943B1 (en) 2006-02-21 2011-12-19 밀리켈빈 테크놀로지스 엘엘씨 Hyperpolarization methods, systems and compositions
GB2498181A (en) * 2011-12-29 2013-07-10 Bruker Biospin Gmbh Device and method for rapid dynamic nuclear polarisation
US9329246B2 (en) 2012-10-03 2016-05-03 Bruker Biospin Ag Method for hyperpolarization transfer in the liquid state
US9404984B2 (en) 2012-11-06 2016-08-02 Bruker Uk Limited Method of hyperpolarization applying brute force using particulate acceleration agents

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545396A (en) * 1994-04-08 1996-08-13 The Research Foundation Of State University Of New York Magnetic resonance imaging using hyperpolarized noble gases
US5617859A (en) 1995-10-02 1997-04-08 General Electric Company Apparatus and methods for magnetic resonance (MR) imaging of cavities using fluids polarized at low temperatures
RU2186405C2 (en) 1996-03-29 2002-07-27 Лоренс Беркли Нэшнл Лэборэтори Amplification of nuclear magnetic resonance and magnetic resonance visualization in presence of hyperpolarized noble gases
CN1224502A (en) * 1996-03-29 1999-07-28 劳伦斯·伯克利国家实验室 Enhancement of NMR and MRI in presence of hyperpolarized noble gases
US5809801A (en) * 1996-03-29 1998-09-22 The Trustees Of Princeton University Cryogenic accumulator for spin-polarized xenon-129
GB9614139D0 (en) 1996-07-05 1996-09-04 Nycomed Imaging As Method
ATE256293T1 (en) * 1997-01-08 2003-12-15 Amersham Health As METHOD FOR GENERATING IMAGE WITH MAGNETIC RESONANCE
CA2290808A1 (en) * 1997-06-19 1998-12-23 Jan Henrik Ardenkjaer-Larsen Overhauser magnetic resonance imaging (ormi) method comprising ex vivo polarization of a magnetic resonance (mr) imaging agent
ATE405297T1 (en) 1997-11-12 2008-09-15 Ge Healthcare As PARA-HYDROGEN LABELED AGENTS AND THEIR USE FOR IMAGING THROUGH NON-PROTON MAGNETIC RESONANCE
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
GB0001727D0 (en) 2000-01-25 2000-03-15 Oxford Instr Uk Ltd Hyperpolarization of a noble gas
DK1330659T3 (en) * 2000-11-03 2006-12-18 Amersham Health As Method and Device for Resolving Hyperpolarized Solid Material for NMR Assays
WO2002036005A1 (en) 2000-11-03 2002-05-10 Amersham Health As Methods and devices for polarised nmr samples
NO20025738D0 (en) * 2002-11-29 2002-11-29 Amersham Health As Method
DE102004002639A1 (en) * 2004-01-19 2005-09-15 Forschungszentrum Jülich GmbH Process for the enrichment of hyperpolarized atomic nuclei and apparatus for carrying out the process
GB0501346D0 (en) * 2005-01-21 2005-03-02 Oxford Instr Molecular Biotool Method of carrying out dynamic nuclear polarization
FR2881226B1 (en) * 2005-01-27 2007-04-27 Commissariat Energie Atomique INCREASING THE POLARIZATION OF NUCLEAR SPINS OF A MOLECULE VIA HARTMANN-HAHN-TYPE POLARIZATION TRANSFER USING THE SOURCE-CREATED MEDIUM DIPOLAR FIELD
GB0514303D0 (en) * 2005-07-12 2005-08-17 Oxford Instr Molecular Biotool Magnet assembly
KR101095943B1 (en) * 2006-02-21 2011-12-19 밀리켈빈 테크놀로지스 엘엘씨 Hyperpolarization methods, systems and compositions
NL2000122C2 (en) * 2006-07-03 2008-01-07 Vialle Alternative Fuel System Buffer holder.
US7631507B2 (en) * 2006-11-02 2009-12-15 General Electric Company Methods and devices for polarized samples for use in MRI
US20080242974A1 (en) * 2007-04-02 2008-10-02 Urbahn John A Method and apparatus to hyperpolarize materials for enhanced mr techniques
US7519492B2 (en) * 2007-05-02 2009-04-14 General Electric Company Apparatus and method for fully automated closed system quality control of a substance

Also Published As

Publication number Publication date
EP2473198A2 (en) 2012-07-11
KR20120101339A (en) 2012-09-13
JP2013503021A (en) 2013-01-31
CN102753201A (en) 2012-10-24
CA2772190A1 (en) 2011-03-03
IN2012DN02418A (en) 2015-08-21
EP2473198A4 (en) 2015-06-24
WO2011026103A2 (en) 2011-03-03
AU2010286413B2 (en) 2014-11-20
WO2011026103A3 (en) 2011-07-21
JP5792726B2 (en) 2015-10-14
AU2010286413A1 (en) 2012-04-05

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