SG149080A1 - Composition comprising a nsaid and paracetamol - Google Patents

Composition comprising a nsaid and paracetamol

Info

Publication number
SG149080A1
SG149080A1 SG200900013-4A SG2009000134A SG149080A1 SG 149080 A1 SG149080 A1 SG 149080A1 SG 2009000134 A SG2009000134 A SG 2009000134A SG 149080 A1 SG149080 A1 SG 149080A1
Authority
SG
Singapore
Prior art keywords
paracetamol
nsaid
composition
forming
melt
Prior art date
Application number
SG200900013-4A
Other languages
English (en)
Inventor
Robert Sherry
Original Assignee
Reckitt Benckiser Healthcare
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt Benckiser Healthcare filed Critical Reckitt Benckiser Healthcare
Publication of SG149080A1 publication Critical patent/SG149080A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/67Phosphorus compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG200900013-4A 2005-09-22 2006-09-07 Composition comprising a nsaid and paracetamol SG149080A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0519350.3A GB0519350D0 (en) 2005-09-22 2005-09-22 Therapeutic agents

Publications (1)

Publication Number Publication Date
SG149080A1 true SG149080A1 (en) 2009-01-29

Family

ID=35335274

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200900013-4A SG149080A1 (en) 2005-09-22 2006-09-07 Composition comprising a nsaid and paracetamol

Country Status (13)

Country Link
US (1) US20090142392A1 (ru)
EP (2) EP1926477B1 (ru)
JP (1) JP2009508916A (ru)
KR (2) KR101434906B1 (ru)
CN (1) CN101267807B (ru)
AU (1) AU2006293798B2 (ru)
CA (1) CA2623281A1 (ru)
GB (1) GB0519350D0 (ru)
PL (2) PL2851068T3 (ru)
RU (1) RU2438656C2 (ru)
SG (1) SG149080A1 (ru)
WO (1) WO2007034135A1 (ru)
ZA (1) ZA200802436B (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080275125A1 (en) 2004-07-07 2008-11-06 Aft Pharmaceuticals Limited Combination Composition
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
KR20100134557A (ko) * 2008-01-11 2010-12-23 씨아이피엘에이 엘티디. 고체 약제학적 투여 제형
JPWO2009128543A1 (ja) * 2008-04-17 2011-08-04 ニプロ株式会社 シリカを含む錠剤の製造方法、錠剤及び錠剤用複合粒子
JP2012505830A (ja) 2008-10-14 2012-03-08 エイエフティ ファーマスーティカルズ リミテッド 医薬品及び医薬品治療
ES2365961B1 (es) * 2010-03-30 2013-01-24 Farmasierra Manufacturing S.L. Formulación farmacéutica a base de ibuprofeno y codeína de estabilidad mejorada.
CN105816434B (zh) * 2016-04-19 2019-09-17 山东新华制药股份有限公司 布洛芬颗粒及其制备方法
WO2019108147A1 (en) 2017-11-29 2019-06-06 İlko İlaç Sanayi̇ Ve Ti̇caret A.Ş. Color stable fixed dose tablet combination of ibuprofen and paracetamol
US20190350883A1 (en) * 2018-05-20 2019-11-21 Luan Chau Pharmaceutical Composition of Acetaminophen/Ibuprofen
US11197830B2 (en) 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
US11779541B2 (en) 2019-03-26 2023-10-10 Johnson & Johnson Consumer Inc. Immediate release dosage form
US11918693B2 (en) * 2019-06-27 2024-03-05 Haleon Us Holdings Llc Ibuprofen and acetaminophen tablet
CN110372713B (zh) * 2019-08-15 2022-05-17 广州市汉普医药有限公司 一种普拉洛芬的精制纯化方法
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271811A (en) * 1988-01-29 1993-12-21 Hoechst Celanese Corporation Process for purifying 2-(4-isobutylphenyl)-propionic acid by vacuum distillation
DE3802619C1 (ru) 1988-01-29 1989-09-07 Hoechst Ag, 6230 Frankfurt, De
DE3833448A1 (de) 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
JP3122748B2 (ja) * 1991-11-29 2001-01-09 ライオン株式会社 イブプロフェン含有解熱鎮痛剤
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
JP3982889B2 (ja) * 1997-11-28 2007-09-26 あすか製薬株式会社 イブプロフェン含有医薬製剤
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
CZ300558B6 (cs) * 1999-12-09 2009-06-17 Reckitt Benckiser Healthcare (Uk) Limited Tabletová kompozice nesteroidního protizánetlivého léciva a zpusob její prípravy
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
PT1804772E (pt) * 2004-08-12 2011-12-02 Reckitt Benckiser Healthcare Grânulos que compreendem um fármaco anti-inflamatório não esteróide e um álcool de açúcar feito por extrusão de fundido
GB0423103D0 (en) * 2004-10-19 2004-11-17 Boots Healthcare Int Ltd Therapeutic agents

Also Published As

Publication number Publication date
EP2851068A3 (en) 2015-05-27
PL1926477T3 (pl) 2017-09-29
ZA200802436B (en) 2009-07-29
GB0519350D0 (en) 2005-11-02
PL2851068T3 (pl) 2020-04-30
KR101434906B1 (ko) 2014-08-27
EP2851068B1 (en) 2019-10-23
EP2851068A2 (en) 2015-03-25
EP1926477A1 (en) 2008-06-04
CN101267807A (zh) 2008-09-17
KR20130141728A (ko) 2013-12-26
AU2006293798A1 (en) 2007-03-29
KR20080047437A (ko) 2008-05-28
RU2438656C2 (ru) 2012-01-10
RU2008115507A (ru) 2009-10-27
WO2007034135A1 (en) 2007-03-29
CA2623281A1 (en) 2007-03-29
EP1926477B1 (en) 2017-04-19
JP2009508916A (ja) 2009-03-05
US20090142392A1 (en) 2009-06-04
AU2006293798B2 (en) 2012-08-16
CN101267807B (zh) 2013-04-10

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