SG148840A1 - Indole derivatives useful for the treatment of cns disorders - Google Patents

Indole derivatives useful for the treatment of cns disorders

Info

Publication number
SG148840A1
SG148840A1 SG200501564-9A SG2005015649A SG148840A1 SG 148840 A1 SG148840 A1 SG 148840A1 SG 2005015649 A SG2005015649 A SG 2005015649A SG 148840 A1 SG148840 A1 SG 148840A1
Authority
SG
Singapore
Prior art keywords
treatment
cns disorders
indole derivatives
derivatives useful
useful
Prior art date
Application number
SG200501564-9A
Other languages
English (en)
Inventor
Benny Bang-Andersen
Jakob Felding
Jan Kehler
Kim Andersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of SG148840A1 publication Critical patent/SG148840A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG200501564-9A 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders SG148840A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000919 2000-06-14
US21244500P 2000-06-16 2000-06-16

Publications (1)

Publication Number Publication Date
SG148840A1 true SG148840A1 (en) 2009-01-29

Family

ID=26068835

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200501564-9A SG148840A1 (en) 2000-06-14 2001-06-13 Indole derivatives useful for the treatment of cns disorders

Country Status (20)

Country Link
US (2) US6890916B2 (pt)
EP (1) EP1294710B1 (pt)
JP (1) JP2004503550A (pt)
KR (1) KR20030007967A (pt)
AR (1) AR028685A1 (pt)
AT (2) ATE374197T1 (pt)
AU (2) AU7388101A (pt)
BG (1) BG107449A (pt)
CA (1) CA2411412C (pt)
CZ (1) CZ200335A3 (pt)
DE (2) DE60130691T2 (pt)
DK (1) DK1468996T3 (pt)
ES (2) ES2290587T3 (pt)
HR (1) HRP20021008A2 (pt)
HU (1) HUP0301735A2 (pt)
NO (1) NO323236B1 (pt)
NZ (1) NZ523076A (pt)
PT (2) PT1468996E (pt)
SG (1) SG148840A1 (pt)
WO (1) WO2001096328A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
EP1468996B1 (en) * 2000-06-14 2007-09-26 H. Lundbeck A/S Indole derivatives for the treatment of CNS disorders
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
WO2003102097A1 (en) * 2002-05-31 2003-12-11 H. Lundbeck A/S The hydrochloride of (s)-(+)-3-[1-[2-(1-acetyl-2,3-dihydro-1h-indol-3-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl]-6-chloro-1h-indole
WO2004020437A1 (en) * 2002-08-29 2004-03-11 H. Lundbeck A/S S-(+)-3-{1-[2-(2,3-dihydro-1h-indol-3-yl)ethyl]-3,6-dihydro-2h-pyridin-4-yl}-6-chloro-1h-indole and acid addition salts thereof
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
WO2004108671A1 (en) * 2003-06-06 2004-12-16 Suven Life Sciences Limited Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them
GB0708186D0 (en) * 2007-04-27 2007-06-06 Merck Sharp & Dohme Therapeutic compounds
SE531698C2 (sv) 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028293A1 (en) * 1996-12-20 1998-07-02 H.Lundbeck A/S Indane or dihydroindole derivatives
WO1999011619A1 (en) * 1997-09-04 1999-03-11 Merck Sharp & Dohme Limited Phenylindole derivatives as 5-ht2a receptor ligands
WO1999058525A1 (en) * 1998-05-13 1999-11-18 Eli Lilly And Company Limited Indole derivatives as 5-ht2a ligands and as serotonine reuptake inhibitors
WO2000031074A2 (en) * 1998-11-19 2000-06-02 Eli Lilly And Company Limited Indole derivatives and their use as serotonin receptor ligands

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
EP0897921A1 (en) * 1997-08-22 1999-02-24 Eli Lilly And Company Limited Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands
WO2000040581A1 (en) * 1999-01-07 2000-07-13 American Home Products Corporation 3,4-dihydro-2h-benzo[1,4]oxazine derivatives
EP1200072A2 (en) * 1999-05-12 2002-05-02 Solvay Pharmaceuticals B.V. Method of treating psychotic disorders
US6642228B1 (en) * 1999-06-24 2003-11-04 Toray Industries, Inc. α1b-adrenergic receptor antagonists
GB2362381A (en) * 2000-05-18 2001-11-21 Lilly Co Eli Pharmaceutically active indolyl-piperidines

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998028293A1 (en) * 1996-12-20 1998-07-02 H.Lundbeck A/S Indane or dihydroindole derivatives
WO1999011619A1 (en) * 1997-09-04 1999-03-11 Merck Sharp & Dohme Limited Phenylindole derivatives as 5-ht2a receptor ligands
WO1999058525A1 (en) * 1998-05-13 1999-11-18 Eli Lilly And Company Limited Indole derivatives as 5-ht2a ligands and as serotonine reuptake inhibitors
WO2000031074A2 (en) * 1998-11-19 2000-06-02 Eli Lilly And Company Limited Indole derivatives and their use as serotonin receptor ligands

Also Published As

Publication number Publication date
DE60111379D1 (de) 2005-07-14
NO323236B1 (no) 2007-02-05
DE60130691T2 (de) 2008-07-17
DE60130691D1 (de) 2007-11-08
AU7388101A (en) 2001-12-24
US20050176729A1 (en) 2005-08-11
US7276508B2 (en) 2007-10-02
US20030191133A1 (en) 2003-10-09
ATE374197T1 (de) 2007-10-15
NZ523076A (en) 2004-09-24
WO2001096328A1 (en) 2001-12-20
PT1294710E (pt) 2005-10-31
ES2290587T3 (es) 2008-02-16
DK1468996T3 (da) 2008-01-07
JP2004503550A (ja) 2004-02-05
CA2411412C (en) 2008-09-02
AU2001273881B2 (en) 2005-12-22
HUP0301735A2 (hu) 2003-08-28
HRP20021008A2 (en) 2005-02-28
EP1294710A1 (en) 2003-03-26
CZ200335A3 (cs) 2003-04-16
ATE297391T1 (de) 2005-06-15
NO20026005L (no) 2002-12-13
DE60111379T2 (de) 2006-03-16
BG107449A (bg) 2003-09-30
AU2001273881B8 (en) 2006-02-09
KR20030007967A (ko) 2003-01-23
NO20026005D0 (no) 2002-12-13
EP1294710B1 (en) 2005-06-08
ES2243508T3 (es) 2005-12-01
PT1468996E (pt) 2007-11-28
US6890916B2 (en) 2005-05-10
AR028685A1 (es) 2003-05-21
CA2411412A1 (en) 2001-12-20

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