SG11202011094PA - Method for preparing oligonucleic acid compound - Google Patents

Method for preparing oligonucleic acid compound

Info

Publication number
SG11202011094PA
SG11202011094PA SG11202011094PA SG11202011094PA SG11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA SG 11202011094P A SG11202011094P A SG 11202011094PA
Authority
SG
Singapore
Prior art keywords
preparing
acid compound
oligonucleic acid
oligonucleic
compound
Prior art date
Application number
SG11202011094PA
Inventor
Yutaro Kotobuki
Fumiya URABE
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of SG11202011094PA publication Critical patent/SG11202011094PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
SG11202011094PA 2018-05-10 2019-05-10 Method for preparing oligonucleic acid compound SG11202011094PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018091231 2018-05-10
PCT/JP2019/018828 WO2019216433A1 (en) 2018-05-10 2019-05-10 Method for producing oligonucleic acid compound

Publications (1)

Publication Number Publication Date
SG11202011094PA true SG11202011094PA (en) 2020-12-30

Family

ID=68468137

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202011094PA SG11202011094PA (en) 2018-05-10 2019-05-10 Method for preparing oligonucleic acid compound

Country Status (9)

Country Link
US (1) US11560401B2 (en)
EP (1) EP3792269A4 (en)
JP (1) JP7394749B2 (en)
KR (1) KR20210008055A (en)
CN (1) CN112384520A (en)
AU (1) AU2019266768B2 (en)
CA (1) CA3099778A1 (en)
SG (1) SG11202011094PA (en)
WO (1) WO2019216433A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109851593B (en) * 2019-02-01 2021-04-16 沈阳药科大学 Triglyceride prodrug based on lymph-mediated transport and preparation method thereof
CA3161586A1 (en) * 2019-11-13 2021-05-20 Nippon Shinyaku Co., Ltd. Method for producing oligonucleic acid compound
CN117279926A (en) * 2021-04-28 2023-12-22 日本新药株式会社 Method for producing oligonucleotide compound
WO2023127918A1 (en) * 2021-12-27 2023-07-06 日本新薬株式会社 Method for producing oligonucleic acid compound

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2130844A5 (en) 1971-03-23 1972-11-10 Commissariat Energie Atomique
JPS5668388A (en) 1979-11-10 1981-06-09 Norin Suisansyo Shokuhin Sogo Kenkyusho Production of cell body of spirulina algae
JP3398378B2 (en) 1989-12-20 2003-04-21 アンチビラルス・インコーポレイテツド Uncharged morpholino-based polymers with phosphorus-containing chiral intersubunit linkages
US7034177B2 (en) 2002-06-13 2006-04-25 Rhodia Inc Process of making phosphordiamidite compounds
US8067571B2 (en) * 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
DK2024499T3 (en) * 2006-05-10 2018-01-29 Sarepta Therapeutics Inc Oligonucleotide Analogs with Cationic Intersubunit Couplings
KR100886139B1 (en) 2007-11-13 2009-02-27 주식회사 삼천리제약 Method for preparing oligonucleotide
CA2884340C (en) 2007-11-15 2017-07-25 Sarepta Therapeutics, Inc. Method of synthesis of morpholino oligomers
JP5548852B2 (en) 2009-05-29 2014-07-16 国立大学法人東京農工大学 Hydrophobic group-bonded nucleoside, hydrophobic group-bonded nucleoside solution, and hydrophobic group-bonded oligonucleotide synthesis method
RS55610B1 (en) * 2010-09-30 2017-06-30 Nippon Shinyaku Co Ltd Morpholino nucleic acid derivative
JP5979139B2 (en) 2011-05-17 2016-08-24 味の素株式会社 Method for producing oligonucleotide
EA035030B1 (en) * 2011-11-18 2020-04-20 Сарепта Терапьютикс, Инк. Modified morpholino oligonucleotide analogues
ES2832531T3 (en) 2011-11-30 2021-06-10 Sarepta Therapeutics Inc Oligonucleotides for the treatment of repeat expansion diseases
WO2013122236A1 (en) 2012-02-17 2013-08-22 味の素株式会社 Base-protected oligonucleotide
US10377789B2 (en) * 2012-09-21 2019-08-13 Osaka University Oligonucleotide and artificial nucleoside having guanidine bridge
EP2921499B1 (en) 2012-11-14 2020-01-22 Takeda Pharmaceutical Company Limited Method for liquid-phase synthesis of nucleic acids
CN105228999B (en) * 2013-05-24 2021-03-02 味之素株式会社 Process for preparing morpholino oligonucleotides
WO2016060135A1 (en) 2014-10-14 2016-04-21 味の素株式会社 Morpholino oligonucleotide manufacturing method
DK3266792T3 (en) 2015-03-04 2021-02-01 Jitsubo Co Ltd Method for peptide synthesis

Also Published As

Publication number Publication date
EP3792269A4 (en) 2022-06-22
JPWO2019216433A1 (en) 2021-05-27
CA3099778A1 (en) 2019-11-14
US20210261596A1 (en) 2021-08-26
KR20210008055A (en) 2021-01-20
US11560401B2 (en) 2023-01-24
WO2019216433A1 (en) 2019-11-14
CN112384520A (en) 2021-02-19
EP3792269A1 (en) 2021-03-17
AU2019266768A1 (en) 2020-12-17
JP7394749B2 (en) 2023-12-08
AU2019266768B2 (en) 2024-02-29

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