SG11202006217YA - Anti-claudin 18.2 antibodies - Google Patents
Anti-claudin 18.2 antibodiesInfo
- Publication number
- SG11202006217YA SG11202006217YA SG11202006217YA SG11202006217YA SG11202006217YA SG 11202006217Y A SG11202006217Y A SG 11202006217YA SG 11202006217Y A SG11202006217Y A SG 11202006217YA SG 11202006217Y A SG11202006217Y A SG 11202006217YA SG 11202006217Y A SG11202006217Y A SG 11202006217YA
- Authority
- SG
- Singapore
- Prior art keywords
- claudin
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862643035P | 2018-03-14 | 2018-03-14 | |
US201962803297P | 2019-02-08 | 2019-02-08 | |
PCT/CN2019/078150 WO2019174617A1 (en) | 2018-03-14 | 2019-03-14 | Anti-claudin 18.2 antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202006217YA true SG11202006217YA (en) | 2020-07-29 |
Family
ID=67908599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202006217YA SG11202006217YA (en) | 2018-03-14 | 2019-03-14 | Anti-claudin 18.2 antibodies |
Country Status (14)
Country | Link |
---|---|
US (1) | US11485782B2 (en) |
EP (1) | EP3765522A4 (en) |
JP (1) | JP2021515583A (en) |
KR (1) | KR20200130831A (en) |
CN (1) | CN112166123B (en) |
AU (1) | AU2019235033A1 (en) |
BR (1) | BR112020014591A2 (en) |
CA (1) | CA3087423A1 (en) |
IL (1) | IL277072A (en) |
MX (1) | MX2020009514A (en) |
RU (1) | RU2020128013A (en) |
SG (1) | SG11202006217YA (en) |
TW (1) | TW202003562A (en) |
WO (1) | WO2019174617A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112166123B (en) | 2018-03-14 | 2022-09-30 | 北京轩义医药科技有限公司 | Anti-claudin 18.2 antibodies |
SG11202108398YA (en) | 2019-02-01 | 2021-08-30 | Novarock Biotherapeutics Ltd | Anti-claudin 18 antibodies and methods of use thereof |
CN112574307B (en) * | 2019-09-29 | 2023-11-28 | 迈威(上海)生物科技股份有限公司 | Anti-human Claudin18.2 antibody and application thereof |
CN112707965A (en) * | 2019-09-30 | 2021-04-27 | 和铂医药(苏州)有限公司 | Antibody targeting CLDN18.2 and preparation method and application thereof |
MX2022005452A (en) | 2019-11-05 | 2022-07-27 | Lanova Medicines Ltd | Antibody-drug conjugates targeting claudin 18.2. |
BR112022012327A2 (en) * | 2019-12-23 | 2022-10-18 | Sotio Biotech A S | ANTIBODIES OR FRAGMENTS THEREOF, NUCLEIC ACID, VECTOR AND HOST CELL |
KR20220119621A (en) * | 2019-12-27 | 2022-08-30 | 난징 레전드 바이오테크 씨오., 엘티디. | CLAUDIN18.2 binding moieties and uses thereof |
CA3167299A1 (en) * | 2020-02-10 | 2021-08-19 | Shanghai Escugen Biotechnology Co., Ltd. | Cldn18.2 antibody and use thereof |
MX2022014332A (en) * | 2020-05-15 | 2022-12-13 | Sichuan Kelun Biotech Biopharmaceutical Co Ltd | Antibody drug conjugate, preparation method therefor and use thereof. |
TWI809426B (en) * | 2020-06-19 | 2023-07-21 | 大陸商信達生物製藥(蘇州)有限公司 | Anti-claudin18.2 antibody and the use thereof |
KR20230024408A (en) * | 2020-07-13 | 2023-02-20 | 상하이 준스 바이오사이언스 컴퍼니 리미티드 | Anti-CLDN-18.2 Antibodies and Uses Thereof |
CN116472350A (en) * | 2020-09-28 | 2023-07-21 | 科望(苏州)生物医药科技有限公司 | Novel anti-CLDN 18 antibodies |
TW202241519A (en) * | 2020-12-23 | 2022-11-01 | 捷克商舒迪安生物技術公司 | Tumor-specific claudin 18.2 antibody-drug conjugates |
WO2022174809A1 (en) * | 2021-02-19 | 2022-08-25 | Suzhou Transcenta Therapeutics Co., Ltd. | Anti-cldn18.2 antibody conjugates |
CN116059391A (en) * | 2021-08-26 | 2023-05-05 | 上海君实生物医药科技股份有限公司 | anti-CLDN-18.2 antibody drug conjugate and use thereof |
WO2023070201A1 (en) * | 2021-10-25 | 2023-05-04 | Fusion Pharmaceuticals Inc. | Claudin 18.2-binding antibodies and fragments thereof |
CN116102649A (en) * | 2021-11-11 | 2023-05-12 | 上海生物制品研究所有限责任公司 | anti-CLDN 18.2 monoclonal antibody and application thereof |
CN117777288A (en) * | 2022-09-29 | 2024-03-29 | 南京博望医药科技有限公司 | Antibodies against claudin 18.2 |
CN116554328B (en) * | 2023-05-11 | 2023-09-29 | 皖南医学院第一附属医院(皖南医学院弋矶山医院) | Single-chain antibody targeting TRBV12, CAR-NK cell and application |
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-
2019
- 2019-03-14 CN CN201980016664.8A patent/CN112166123B/en active Active
- 2019-03-14 EP EP19768583.7A patent/EP3765522A4/en not_active Withdrawn
- 2019-03-14 MX MX2020009514A patent/MX2020009514A/en unknown
- 2019-03-14 AU AU2019235033A patent/AU2019235033A1/en not_active Abandoned
- 2019-03-14 JP JP2020549599A patent/JP2021515583A/en active Pending
- 2019-03-14 SG SG11202006217YA patent/SG11202006217YA/en unknown
- 2019-03-14 CA CA3087423A patent/CA3087423A1/en active Pending
- 2019-03-14 WO PCT/CN2019/078150 patent/WO2019174617A1/en active Application Filing
- 2019-03-14 US US16/980,294 patent/US11485782B2/en active Active
- 2019-03-14 TW TW108108735A patent/TW202003562A/en unknown
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MX2020009514A (en) | 2020-12-07 |
EP3765522A4 (en) | 2022-05-18 |
BR112020014591A2 (en) | 2020-12-01 |
TW202003562A (en) | 2020-01-16 |
RU2020128013A (en) | 2022-04-15 |
EP3765522A1 (en) | 2021-01-20 |
WO2019174617A1 (en) | 2019-09-19 |
CN112166123B (en) | 2022-09-30 |
US20210009686A1 (en) | 2021-01-14 |
KR20200130831A (en) | 2020-11-20 |
US11485782B2 (en) | 2022-11-01 |
CN112166123A (en) | 2021-01-01 |
JP2021515583A (en) | 2021-06-24 |
CA3087423A1 (en) | 2019-09-19 |
IL277072A (en) | 2020-10-29 |
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