SG11202002014PA - Particle sorting in a microfluidic system - Google Patents

Particle sorting in a microfluidic system

Info

Publication number
SG11202002014PA
SG11202002014PA SG11202002014PA SG11202002014PA SG11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA
Authority
SG
Singapore
Prior art keywords
microfluidic system
particle sorting
sorting
particle
microfluidic
Prior art date
Application number
SG11202002014PA
Inventor
Raphael Clément Li-Ming Doineau
Arnaud Reitz
Marcel Reichen
Original Assignee
Hifibio Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hifibio Sas filed Critical Hifibio Sas
Publication of SG11202002014PA publication Critical patent/SG11202002014PA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502776Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30Micromixers
    • B01F33/301Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0636Focussing flows, e.g. to laminate flows
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652Sorting or classification of particles or molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • G01N15/149
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G01N2015/1413Hydrodynamic focussing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G01N2015/1415Control of particle position
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1486Counting the particles
SG11202002014PA 2017-09-19 2018-09-19 Particle sorting in a microfluidic system SG11202002014PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17191962 2017-09-19
PCT/EP2018/075393 WO2019057794A1 (en) 2017-09-19 2018-09-19 Particle sorting in a microfluidic system

Publications (1)

Publication Number Publication Date
SG11202002014PA true SG11202002014PA (en) 2020-04-29

Family

ID=59914402

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002014PA SG11202002014PA (en) 2017-09-19 2018-09-19 Particle sorting in a microfluidic system

Country Status (8)

Country Link
US (1) US11738344B2 (en)
EP (1) EP3684507B1 (en)
JP (1) JP7332586B2 (en)
CN (1) CN111132765B (en)
AU (1) AU2018335223A1 (en)
CA (1) CA3076194A1 (en)
SG (1) SG11202002014PA (en)
WO (1) WO2019057794A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008130977A2 (en) * 2007-04-16 2008-10-30 The General Hospital Corporation D/B/A Massachusetts General Hospital Systems and methods for particle focusing in microchannels
CN111235085A (en) * 2020-01-20 2020-06-05 丁林 Method for separating single cell based on static liquid drop array
CA3172909A1 (en) * 2020-03-18 2021-09-23 Chan Zuckerberg Biohub, Inc. Single-cell combinatorial indexed cytometry sequencing
CN113275047A (en) * 2021-04-30 2021-08-20 北京机械设备研究所 Microfluidic chip and application thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6454945B1 (en) * 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
CA2222126A1 (en) * 1995-06-16 1997-01-03 Fred K. Forster Microfabricated differential extraction device and method
AU2606301A (en) 1999-12-29 2001-07-09 Union Biometrica, Inc. High viscosity sheath reagent for flow cytometry
US20020003001A1 (en) * 2000-05-24 2002-01-10 Weigl Bernhard H. Surface tension valves for microfluidic applications
US7901939B2 (en) * 2002-05-09 2011-03-08 University Of Chicago Method for performing crystallization and reactions in pressure-driven fluid plugs
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
JP4341372B2 (en) * 2003-10-30 2009-10-07 コニカミノルタホールディングス株式会社 Liquid mixing method, mixing apparatus and mixing system
EP1711796A1 (en) * 2004-02-04 2006-10-18 Evotec Technologies GmbH Microfluidic system and associated operational method
JP2005224775A (en) * 2004-02-16 2005-08-25 Fuji Xerox Co Ltd Method and apparatus for treating fine particle
US7442339B2 (en) * 2004-03-31 2008-10-28 Intel Corporation Microfluidic apparatus, Raman spectroscopy systems, and methods for performing molecular reactions
US7315374B2 (en) 2004-06-24 2008-01-01 Intel Corporation Real-time monitoring optically trapped carbon nanotubes
GB2436616A (en) * 2006-03-29 2007-10-03 Inverness Medical Switzerland Assay device and method
WO2008130977A2 (en) * 2007-04-16 2008-10-30 The General Hospital Corporation D/B/A Massachusetts General Hospital Systems and methods for particle focusing in microchannels
JP2009162664A (en) 2008-01-08 2009-07-23 Sony Corp Detection method using channel and detection method for interaction, and detector
US8855103B2 (en) 2008-01-17 2014-10-07 Blackberry Limited Personal network access control system and method
JP2009180684A (en) 2008-01-31 2009-08-13 Canon Inc Method for controlling fluid
EP2349566B1 (en) * 2008-10-03 2016-01-06 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
CN102713640B (en) 2009-06-10 2015-09-16 辛温尼奥生物***公司 Sheath stream apparatus and method
US20120211084A1 (en) 2009-09-02 2012-08-23 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
FR2972117B1 (en) * 2011-03-04 2013-12-20 Centre Nat Rech Scient MICROFLUIDIC SYSTEM FOR CONTROLLING A PROFILE OF CONCENTRATION OF MOLECULES LIKELY TO STIMULATE A TARGET
EP2691676B1 (en) * 2011-03-30 2019-03-27 Bio-Rad Laboratories, Inc. Injection of multiple volumes into or out of droplets
WO2013158737A1 (en) * 2012-04-17 2013-10-24 Regents Of The University Of Minnesota Inlet and outlet geometries for a vertical three-stream microfluidic device
SG2013090790A (en) 2013-12-04 2015-07-30 Clearbridge Mfluidics Pte Ltd A microfluidic device
WO2015088299A1 (en) * 2013-12-09 2015-06-18 Vilnius University Method for production of biopolymer-based droplets and particles in a microfluidic system
CN103667057B (en) * 2013-12-30 2015-10-28 中国科学院苏州纳米技术与纳米仿生研究所 The monitoring method of cell migration biological behaviour after being wound based on the cell of micro-fluidic chip
EP3889325A1 (en) * 2014-06-26 2021-10-06 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
FR3024738B1 (en) * 2014-08-11 2018-06-15 Genes Diffusion DEVICE AND METHOD FOR SELECTING EUKARYOTIC CELLS IN A TRANSPARENCY CHANNEL BY ALTERATION OF EUKARYOTIC CELLS USING ELECTROMAGNETIC RADIATION
CN105688721B (en) * 2016-01-06 2018-01-12 中国计量学院 For generating the micro-fluidic chip of spherical microbubble

Also Published As

Publication number Publication date
US11738344B2 (en) 2023-08-29
CA3076194A1 (en) 2019-03-28
WO2019057794A1 (en) 2019-03-28
JP7332586B2 (en) 2023-08-23
AU2018335223A1 (en) 2020-04-23
JP2020534142A (en) 2020-11-26
EP3684507A1 (en) 2020-07-29
US20200215545A1 (en) 2020-07-09
EP3684507C0 (en) 2023-06-07
CN111132765A (en) 2020-05-08
CN111132765B (en) 2022-05-13
EP3684507B1 (en) 2023-06-07

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