SG11202002014PA - Particle sorting in a microfluidic system - Google Patents
Particle sorting in a microfluidic systemInfo
- Publication number
- SG11202002014PA SG11202002014PA SG11202002014PA SG11202002014PA SG11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA SG 11202002014P A SG11202002014P A SG 11202002014PA
- Authority
- SG
- Singapore
- Prior art keywords
- microfluidic system
- particle sorting
- sorting
- particle
- microfluidic
- Prior art date
Links
- 239000002245 particle Substances 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502776—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for focusing or laminating flows
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
- B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0636—Focussing flows, e.g. to laminate flows
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
- B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
-
- G01N15/149—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
- G01N2015/1413—Hydrodynamic focussing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
- G01N2015/1415—Control of particle position
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Electro-optical investigation, e.g. flow cytometers
- G01N2015/1486—Counting the particles
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17191962 | 2017-09-19 | ||
PCT/EP2018/075393 WO2019057794A1 (en) | 2017-09-19 | 2018-09-19 | Particle sorting in a microfluidic system |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202002014PA true SG11202002014PA (en) | 2020-04-29 |
Family
ID=59914402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202002014PA SG11202002014PA (en) | 2017-09-19 | 2018-09-19 | Particle sorting in a microfluidic system |
Country Status (8)
Country | Link |
---|---|
US (1) | US11738344B2 (en) |
EP (1) | EP3684507B1 (en) |
JP (1) | JP7332586B2 (en) |
CN (1) | CN111132765B (en) |
AU (1) | AU2018335223A1 (en) |
CA (1) | CA3076194A1 (en) |
SG (1) | SG11202002014PA (en) |
WO (1) | WO2019057794A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008130977A2 (en) * | 2007-04-16 | 2008-10-30 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
CN111235085A (en) * | 2020-01-20 | 2020-06-05 | 丁林 | Method for separating single cell based on static liquid drop array |
CA3172909A1 (en) * | 2020-03-18 | 2021-09-23 | Chan Zuckerberg Biohub, Inc. | Single-cell combinatorial indexed cytometry sequencing |
CN113275047A (en) * | 2021-04-30 | 2021-08-20 | 北京机械设备研究所 | Microfluidic chip and application thereof |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6454945B1 (en) * | 1995-06-16 | 2002-09-24 | University Of Washington | Microfabricated devices and methods |
CA2222126A1 (en) * | 1995-06-16 | 1997-01-03 | Fred K. Forster | Microfabricated differential extraction device and method |
AU2606301A (en) | 1999-12-29 | 2001-07-09 | Union Biometrica, Inc. | High viscosity sheath reagent for flow cytometry |
US20020003001A1 (en) * | 2000-05-24 | 2002-01-10 | Weigl Bernhard H. | Surface tension valves for microfluidic applications |
US7901939B2 (en) * | 2002-05-09 | 2011-03-08 | University Of Chicago | Method for performing crystallization and reactions in pressure-driven fluid plugs |
US7347617B2 (en) * | 2003-08-19 | 2008-03-25 | Siemens Healthcare Diagnostics Inc. | Mixing in microfluidic devices |
JP4341372B2 (en) * | 2003-10-30 | 2009-10-07 | コニカミノルタホールディングス株式会社 | Liquid mixing method, mixing apparatus and mixing system |
EP1711796A1 (en) * | 2004-02-04 | 2006-10-18 | Evotec Technologies GmbH | Microfluidic system and associated operational method |
JP2005224775A (en) * | 2004-02-16 | 2005-08-25 | Fuji Xerox Co Ltd | Method and apparatus for treating fine particle |
US7442339B2 (en) * | 2004-03-31 | 2008-10-28 | Intel Corporation | Microfluidic apparatus, Raman spectroscopy systems, and methods for performing molecular reactions |
US7315374B2 (en) | 2004-06-24 | 2008-01-01 | Intel Corporation | Real-time monitoring optically trapped carbon nanotubes |
GB2436616A (en) * | 2006-03-29 | 2007-10-03 | Inverness Medical Switzerland | Assay device and method |
WO2008130977A2 (en) * | 2007-04-16 | 2008-10-30 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Systems and methods for particle focusing in microchannels |
JP2009162664A (en) | 2008-01-08 | 2009-07-23 | Sony Corp | Detection method using channel and detection method for interaction, and detector |
US8855103B2 (en) | 2008-01-17 | 2014-10-07 | Blackberry Limited | Personal network access control system and method |
JP2009180684A (en) | 2008-01-31 | 2009-08-13 | Canon Inc | Method for controlling fluid |
EP2349566B1 (en) * | 2008-10-03 | 2016-01-06 | Micronics, Inc. | Microfluidic apparatus and methods for performing blood typing and crossmatching |
CN102713640B (en) | 2009-06-10 | 2015-09-16 | 辛温尼奥生物***公司 | Sheath stream apparatus and method |
US20120211084A1 (en) | 2009-09-02 | 2012-08-23 | President And Fellows Of Harvard College | Multiple emulsions created using jetting and other techniques |
FR2972117B1 (en) * | 2011-03-04 | 2013-12-20 | Centre Nat Rech Scient | MICROFLUIDIC SYSTEM FOR CONTROLLING A PROFILE OF CONCENTRATION OF MOLECULES LIKELY TO STIMULATE A TARGET |
EP2691676B1 (en) * | 2011-03-30 | 2019-03-27 | Bio-Rad Laboratories, Inc. | Injection of multiple volumes into or out of droplets |
WO2013158737A1 (en) * | 2012-04-17 | 2013-10-24 | Regents Of The University Of Minnesota | Inlet and outlet geometries for a vertical three-stream microfluidic device |
SG2013090790A (en) | 2013-12-04 | 2015-07-30 | Clearbridge Mfluidics Pte Ltd | A microfluidic device |
WO2015088299A1 (en) * | 2013-12-09 | 2015-06-18 | Vilnius University | Method for production of biopolymer-based droplets and particles in a microfluidic system |
CN103667057B (en) * | 2013-12-30 | 2015-10-28 | 中国科学院苏州纳米技术与纳米仿生研究所 | The monitoring method of cell migration biological behaviour after being wound based on the cell of micro-fluidic chip |
EP3889325A1 (en) * | 2014-06-26 | 2021-10-06 | 10X Genomics, Inc. | Methods of analyzing nucleic acids from individual cells or cell populations |
FR3024738B1 (en) * | 2014-08-11 | 2018-06-15 | Genes Diffusion | DEVICE AND METHOD FOR SELECTING EUKARYOTIC CELLS IN A TRANSPARENCY CHANNEL BY ALTERATION OF EUKARYOTIC CELLS USING ELECTROMAGNETIC RADIATION |
CN105688721B (en) * | 2016-01-06 | 2018-01-12 | 中国计量学院 | For generating the micro-fluidic chip of spherical microbubble |
-
2018
- 2018-09-19 JP JP2020514716A patent/JP7332586B2/en active Active
- 2018-09-19 CA CA3076194A patent/CA3076194A1/en active Pending
- 2018-09-19 AU AU2018335223A patent/AU2018335223A1/en not_active Abandoned
- 2018-09-19 SG SG11202002014PA patent/SG11202002014PA/en unknown
- 2018-09-19 CN CN201880060671.3A patent/CN111132765B/en active Active
- 2018-09-19 US US16/648,538 patent/US11738344B2/en active Active
- 2018-09-19 WO PCT/EP2018/075393 patent/WO2019057794A1/en unknown
- 2018-09-19 EP EP18783369.4A patent/EP3684507B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
US11738344B2 (en) | 2023-08-29 |
CA3076194A1 (en) | 2019-03-28 |
WO2019057794A1 (en) | 2019-03-28 |
JP7332586B2 (en) | 2023-08-23 |
AU2018335223A1 (en) | 2020-04-23 |
JP2020534142A (en) | 2020-11-26 |
EP3684507A1 (en) | 2020-07-29 |
US20200215545A1 (en) | 2020-07-09 |
EP3684507C0 (en) | 2023-06-07 |
CN111132765A (en) | 2020-05-08 |
CN111132765B (en) | 2022-05-13 |
EP3684507B1 (en) | 2023-06-07 |
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