SG11201909107YA - Stenosis treatment - Google Patents

Stenosis treatment

Info

Publication number
SG11201909107YA
SG11201909107YA SG11201909107YA SG11201909107YA SG 11201909107Y A SG11201909107Y A SG 11201909107YA SG 11201909107Y A SG11201909107Y A SG 11201909107YA SG 11201909107Y A SG11201909107Y A SG 11201909107YA
Authority
SG
Singapore
Prior art keywords
international
pct
alloa
inglewood
lodge
Prior art date
Application number
Inventor
Eamon Mcerlean
Gary Beale
Matthew Donal Kidd
Original Assignee
Emblation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emblation Ltd filed Critical Emblation Ltd
Publication of SG11201909107YA publication Critical patent/SG11201909107YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/02—Radiation therapy using microwaves
    • A61N5/022—Apparatus adapted for a specific treatment
    • A61N5/025—Warming the body, e.g. hyperthermia treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/02—Radiation therapy using microwaves
    • A61N5/04—Radiators for near-field treatment
    • A61N5/045—Radiators for near-field treatment specially adapted for treatment inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
    • A61B2018/1861—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument inserted into a body lumen or cavity, e.g. a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Seats For Vehicles (AREA)

Abstract

MICROWAVESOURCE SYSTEM CONTROLLER REFLECTION MONITORING SYSTEM PRESSURE SENSING SYSTEM MANIFOLD FIGURE 20 1 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 04 October 2018 (04.10.2018) W I PO I PCT 011101 V III o Ho Em ono imiou oimIE (10) International Publication Number WO 2018/178659 Al (51) International Patent Classification: A61P 9/10 (2006.01) A61B 18/18 (2006.01) (21) International Application Number: PCT/GB2018/050807 (22) International Filing Date: 28 March 2018 (28.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/477,816 28 March 2017 (28.03.2017) US (71) Applicant: EMBLATION LIMITED [GB/GB]; 3 For- rester Lodge, Inglewood, Alloa FK10 2HU (GB). (72) Inventors; and (71) Applicants: MCERLEAN, Eamon [GB/GB]; c/o Em- blation Limited, 3 Forrester Lodge, Inglewood, Alloa FK10 2HU (GB). BEALE, Gary [GB/GB]; Farringford, St Margaret's Drive, Dunblane FK15 ODP (GB). KIDD, Matthew Donal [GB/GB]; 23 Fountain Road, Bridge of Al- lan, Stirling FK9 4AT (GB). (74) Agent: MARKS & CLERK LLP; Aurora, 120 Bothwell Street, Glasgow G2 7JS (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) (54) Title: STENOSIS TREATMENT 1-1 01 SO 00 N 1-1 O (57) : The present invention provides heat and heat based treatments that may be used to modulate, inhibit and/or prevent one or more of the processes that contribute to certain vascular and/or arterial complications.
SG11201909107Y 2017-03-28 2018-03-28 Stenosis treatment SG11201909107YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762477816P 2017-03-28 2017-03-28
PCT/GB2018/050807 WO2018178659A1 (en) 2017-03-28 2018-03-28 Stenosis treatment

Publications (1)

Publication Number Publication Date
SG11201909107YA true SG11201909107YA (en) 2019-11-28

Family

ID=61868545

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201909107Y SG11201909107YA (en) 2017-03-28 2018-03-28 Stenosis treatment
SG10202110763WA SG10202110763WA (en) 2017-03-28 2018-03-28 Stenosis treatment

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202110763WA SG10202110763WA (en) 2017-03-28 2018-03-28 Stenosis treatment

Country Status (11)

Country Link
US (1) US11980769B2 (en)
EP (1) EP3600551A1 (en)
JP (2) JP2020512151A (en)
KR (1) KR20200002862A (en)
CN (1) CN110769897B (en)
AU (1) AU2018242490A1 (en)
BR (1) BR112019020555A2 (en)
CA (1) CA3058380A1 (en)
RU (1) RU2019134174A (en)
SG (2) SG11201909107YA (en)
WO (1) WO2018178659A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11963716B2 (en) 2010-07-19 2024-04-23 Emblation Limited Apparatus and method for the treatment of dermatological diseases or conditions
GB2541749B (en) 2015-08-31 2020-12-09 Emblation Ltd An interference suppression apparatus and method
US11497926B2 (en) 2016-08-08 2022-11-15 Emblation Limited Method and apparatus for the treatment, management and/or control of pain
US20200215316A1 (en) * 2019-01-03 2020-07-09 Konstantinos Marmagkiolis Apparatus with Contrast-Coated Balloon and Methods
GB202011414D0 (en) 2020-07-23 2020-09-09 Emblation Ltd Electromagnetic energy delivery apparatus and method
ES2914838A1 (en) * 2022-01-07 2022-06-16 Conic Vascular Espana Sl Thermal balloon for stenosis treatment (Machine-translation by Google Translate, not legally binding)

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4149170A (en) 1976-12-09 1979-04-10 The United States Of America As Represented By The Secretary Of The Army Multiport cable choke
US4517975A (en) 1983-06-06 1985-05-21 Garito Jon C Electrosurgical electrode for matrisectomy
US4914717A (en) 1989-02-13 1990-04-03 Jmk International, Inc. Microwave actuable heating pad and method
WO1991003207A1 (en) * 1989-09-08 1991-03-21 Boston Scientific Corporation Physiologic low stress angioplasty
US5091707A (en) 1990-08-13 1992-02-25 Wollmerschauser Steven M Coaxial cable shield filter
US5195965A (en) 1991-03-07 1993-03-23 Shantha Totada R Method and apparatus for localized treatment of human viral infections and cancers
US5272301A (en) 1991-04-26 1993-12-21 Mmtc, Inc. Thermostatically-controlled microwave used for treatment of internal tissue of the eye
US5275597A (en) 1992-05-18 1994-01-04 Baxter International Inc. Percutaneous transluminal catheter and transmitter therefor
EP0597463A3 (en) 1992-11-13 1996-11-06 Dornier Med Systems Inc Thermotherapiesonde.
US5507791A (en) 1993-08-31 1996-04-16 Sit'ko; Sergei P. Microwave resonance therapy
US5683386A (en) 1995-11-20 1997-11-04 Ellman; Alan G. Electrosurgical electrode for nail spicule removal procedure
US6047216A (en) * 1996-04-17 2000-04-04 The United States Of America Represented By The Administrator Of The National Aeronautics And Space Administration Endothelium preserving microwave treatment for atherosclerosis
US5993480A (en) 1997-01-13 1999-11-30 Burrows; Christina Microwavable heating pad with heat activated fragrance
US6223085B1 (en) 1997-05-06 2001-04-24 Urologix, Inc. Device and method for preventing restenosis
US5879379A (en) 1997-06-25 1999-03-09 Mason; Patricia T. Facial heat transfer device with plural containers
US6104959A (en) 1997-07-31 2000-08-15 Microwave Medical Corp. Method and apparatus for treating subcutaneous histological features
US7981112B1 (en) 1997-08-12 2011-07-19 Joseph Neev Home use device and methods for treating skin conditions
US6710673B1 (en) 1998-06-26 2004-03-23 Thomas Jokerst Return path noise reducer
US6520982B1 (en) 2000-06-08 2003-02-18 Kci Licensing, Inc. Localized liquid therapy and thermotherapy device
JP4579448B2 (en) 2000-06-12 2010-11-10 マスプロ電工株式会社 Noise removal device
DK1296711T3 (en) 2000-06-26 2006-08-28 Stressgen Biotechnologies Corp HPV-E7 for the treatment of human papillomavirus
CN1132638C (en) 2000-07-14 2003-12-31 北京东方康威科技发展中心 Millimetre wave therapeutical apparatus
US6528076B2 (en) 2001-07-06 2003-03-04 Magic Herb Corp. Topical compositions and methods for treating pain
US7048756B2 (en) 2002-01-18 2006-05-23 Apasara Medical Corporation System, method and apparatus for evaluating tissue temperature
US7494502B2 (en) 2002-02-11 2009-02-24 Keraderm, Llc Alteration of the skin and nail for the prevention and treatment of skin and nail infections
US9393396B2 (en) 2002-02-14 2016-07-19 Gholam A. Peyman Method and composition for hyperthermally treating cells
CA2512161A1 (en) 2003-01-28 2004-08-12 Shanghai Sunway Biotech Co., Ltd Hyperthermia oncolysis co-therapy
JP2007516012A (en) 2003-05-16 2007-06-21 ウェイバークス インコーポレーテッド Method and apparatus for treating infectious diseases in keratinized tissue
US20050251231A1 (en) 2004-05-04 2005-11-10 Goldberg Leonard H Treatment method and apparatus for basal cell carcinoma
US7052283B2 (en) 2004-06-18 2006-05-30 John Mezzalingua Associates, Inc. Sheath current attenuator for coaxial cable
US9713730B2 (en) * 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US7742795B2 (en) * 2005-03-28 2010-06-22 Minnow Medical, Inc. Tuned RF energy for selective treatment of atheroma and other target tissues and/or structures
US20060265034A1 (en) 2005-04-05 2006-11-23 Ams Medical Sa Microwave devices for treating biological samples and tissue and methods for using same
US7850683B2 (en) 2005-05-20 2010-12-14 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
JP5312337B2 (en) 2006-10-18 2013-10-09 べシックス・バスキュラー・インコーポレイテッド Regulated RF energy and electrical tissue characterization for selective treatment of target tissues
GB0624584D0 (en) 2006-12-08 2007-01-17 Medical Device Innovations Ltd Skin treatment apparatus and method
US20080149100A1 (en) 2006-12-20 2008-06-26 Gerrit Jan Van Holst Antiviral Heat Treatment
WO2008131306A1 (en) 2007-04-19 2008-10-30 The Foundry, Inc. Systems and methods for creating an effect using microwave energy to specified tissue
ES2488565T3 (en) 2007-04-19 2014-08-27 Miramar Labs, Inc. Devices and systems for the non-invasive distribution of microwave therapy
US8882753B2 (en) 2008-07-14 2014-11-11 Syneron Medical Ltd Devices and methods for percutaneous energy delivery
US8403924B2 (en) 2008-09-03 2013-03-26 Vivant Medical, Inc. Shielding for an isolation apparatus used in a microwave generator
JP6083928B2 (en) * 2008-10-21 2017-02-22 マイクロキューブ， エルエルシー Method and apparatus for applying energy to body tissue
CN107898498B (en) * 2008-10-21 2021-06-11 微立方有限责任公司 Method and apparatus for applying energy to body tissue
US20150024961A1 (en) 2008-10-30 2015-01-22 Caris Life Sciences Switzerland Holdings Gmbh Methods and systems of using biomarkers for determining phenotypes
JP5406933B2 (en) * 2008-11-10 2014-02-05 マイクロキューブ， エルエルシー Method and apparatus for applying energy to body tissue
US20130178383A1 (en) 2008-11-12 2013-07-11 David Spetzler Vesicle isolation methods
EP2555700B1 (en) * 2010-04-06 2015-06-03 Holaira, Inc. System for pulmonary treatment
JP6153865B2 (en) * 2010-05-03 2017-06-28 ニューウェーブ メディカル, インコーポレイテッドNeuwave Medical, Inc. Energy delivery system
US11963716B2 (en) 2010-07-19 2024-04-23 Emblation Limited Apparatus and method for the treatment of dermatological diseases or conditions
US9662510B2 (en) 2010-07-19 2017-05-30 Emblation Limited Apparatus and method for the treatment of dermatological diseases or conditions
US9028476B2 (en) 2011-02-03 2015-05-12 Covidien Lp Dual antenna microwave resection and ablation device, system and method of use
US9498284B2 (en) 2011-05-31 2016-11-22 Emblation Limited Treating and preventing nail disorders
EP2760532B1 (en) * 2011-09-30 2019-08-28 Covidien LP Energy delivery device
GB201120779D0 (en) 2011-12-02 2012-01-11 Immodulon Therapeutics Ltd Cancer therapy
GB201209573D0 (en) 2012-05-30 2012-07-11 Emblation Ltd An apparatus and method for energy delivery
US20140066837A1 (en) 2012-07-26 2014-03-06 Ronald L. Moy Skin care compositions and methods
WO2014079148A1 (en) * 2012-11-21 2014-05-30 The Hong Kong University Of Science And Technology Low force thrombectomy device
WO2014134197A1 (en) 2013-03-01 2014-09-04 Empi, Inc. Systems and methods for wireless control of noninvasive electrotherapy
US10076384B2 (en) * 2013-03-08 2018-09-18 Symple Surgical, Inc. Balloon catheter apparatus with microwave emitter
EP3226795B1 (en) * 2014-12-03 2020-08-26 Metavention, Inc. Systems for modulating nerves or other tissue
GB2541749B (en) 2015-08-31 2020-12-09 Emblation Ltd An interference suppression apparatus and method
US11497926B2 (en) 2016-08-08 2022-11-15 Emblation Limited Method and apparatus for the treatment, management and/or control of pain
CN111836666A (en) 2017-11-09 2020-10-27 蒙特非奥里医疗中心 Low energy immunosensitization for the treatment of cancer and metastasis
US20190255348A1 (en) 2018-02-16 2019-08-22 Emblation Limited Apparatus and method for the treatment of melanoma
US20190274758A1 (en) 2018-02-16 2019-09-12 Emblation Limited Apparatus and method for the treatment of Epidermal Dysplasias
US20200353278A1 (en) 2019-05-10 2020-11-12 Emblation Limited Devices and methods for treatments using microwave energy

Also Published As

Publication number Publication date
JP2023093540A (en) 2023-07-04
KR20200002862A (en) 2020-01-08
RU2019134174A (en) 2021-04-28
WO2018178659A1 (en) 2018-10-04
CA3058380A1 (en) 2018-10-04
EP3600551A1 (en) 2020-02-05
US20180280715A1 (en) 2018-10-04
BR112019020555A2 (en) 2020-04-28
CN110769897B (en) 2024-02-23
US11980769B2 (en) 2024-05-14
CN110769897A (en) 2020-02-07
AU2018242490A1 (en) 2019-11-14
SG10202110763WA (en) 2021-11-29
RU2019134174A3 (en) 2021-12-17
JP2020512151A (en) 2020-04-23

Similar Documents

Publication Publication Date Title
SG11201909107YA (en) Stenosis treatment
SG11201910019PA (en) Microorganisms and methods for producing cannabinoids and cannabinoid derivatives
SG11201901390TA (en) Tetracycline compounds and methods of treatment
SG11201811564QA (en) Methods of treating ovarian cancer
SG11201811338VA (en) A novel botulinum neurotoxin and its derivatives
SG11201906386XA (en) Combination therapy involving diaryl macrocyclic compounds
SG11201901700UA (en) Biaryl compounds useful as immunomodulators
SG11201900163PA (en) Macrocycle kinase inhibitors
SG11201806322QA (en) Maytansinoid derivatives, conjugates thereof, and methods of use
SG11201807784SA (en) 3-desoxy derivative and pharmaceutical compositions thereof
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201907604UA (en) Crystalline forms of the 4-pyrimidinesulfamide derivative aprocitentan
SG11201804263PA (en) Cancer treatment using 2-deoxy-2-fluoro-l-fucose in combination with a checkpoint inhibitor
SG11201908743SA (en) Methods and compositions for modulation of immune cells
SG11201901063SA (en) Therapeutic agents for neurodegenerative diseases
SG11201901048VA (en) Pharmaceutical compositions and uses directed to lysosomal storage disorders
SG11201907927SA (en) Binding molecules that specifically bind to tau
SG11201808713YA (en) Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier
SG11201805387RA (en) Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
SG11201909837YA (en) Methods for treating lung disorders
SG11201901925RA (en) Methods of treating acute kidney injury
SG11201809882XA (en) Pharmaceutical combinations for treating cancer
SG11201906778RA (en) Improved methods for assessing risk of developing breast cancer
SG11201908513RA (en) Peptides for treatment of diabetes
SG11201806622PA (en) Egfl6 specific monoclonal antibodies and methods of their use