SG11201901925RA - Methods of treating acute kidney injury - Google Patents

Methods of treating acute kidney injury

Info

Publication number
SG11201901925RA
SG11201901925RA SG11201901925RA SG11201901925RA SG11201901925RA SG 11201901925R A SG11201901925R A SG 11201901925RA SG 11201901925R A SG11201901925R A SG 11201901925RA SG 11201901925R A SG11201901925R A SG 11201901925RA SG 11201901925R A SG11201901925R A SG 11201901925RA
Authority
SG
Singapore
Prior art keywords
international
rule
english
pct
applicant
Prior art date
Application number
SG11201901925RA
Inventor
Bharat Lagu
Michael Patane
Effie Tozzo
Scott Trzaska
Original Assignee
Mitobridge Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitobridge Inc filed Critical Mitobridge Inc
Publication of SG11201901925RA publication Critical patent/SG11201901925RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111111111111111101111111111111111111001111111111111111111111111111110111111 Organization 0 International Bureau (10) International Publication Number (43) International Publication Date ......0\"\" WO 2018/067857 Al 12 April 2018 (12.04.2018) WIP0 1 PCT (51) International Patent Classification: A61K 31/192 (2006.01) A61K 31/4439 (2006.01) Published: A61K 31/4192 (2006.01) A61P 13/12 (2006.01) — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the (21) International Application Number: claims and to be republished in the event of receipt of PCT/US2017/055400 amendments (Rule 48.2(h)) (22) International Filing Date: 05 October 2017 (05.10.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/404,390 05 October 2016 (05.10.2016) US (71) Applicant: MITOBRIDGE, INC. [US/US]; 1030 Massa- chusetts Avenue, Suite 200, Cambridge, MA 02138 (US). (72) Inventors: LAGU, Bharat; 21 Lexington Drive, Acton, MA 01720 (US). PATANE, Michael; 6 Westwind Road, Andover, MA 01810 (US). TOZZO, Effie; 898 Massa- chusetts Avenue, Lexington, MA 02420 (US). TRZASKA, Scott; 8 Renzi Road, Raritan, NJ 08869 (US). Agent: DAVIS, Steven, G. et al.; McCarter & English, LLP, 265 Franklin Street, Boston, MA 02110 (US). (74) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (81) — Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (84) under Rule 4.17: ,- 1 Declarations ..! — IN in — GC IN as to applicant's entitlement to apply for and be granted a patent (Rule 4.1700) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) 0 --.... 00 1-1 (54) Title: METHODS OF TREATING ACUTE KIDNEY INJURY 0 ei (57) : The present invention is directed to methods of treating a human patient with acute kidney injury.
SG11201901925RA 2016-10-05 2017-10-05 Methods of treating acute kidney injury SG11201901925RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662404390P 2016-10-05 2016-10-05
PCT/US2017/055400 WO2018067857A1 (en) 2016-10-05 2017-10-05 Methods of treating acute kidney injury

Publications (1)

Publication Number Publication Date
SG11201901925RA true SG11201901925RA (en) 2019-04-29

Family

ID=60153507

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901925RA SG11201901925RA (en) 2016-10-05 2017-10-05 Methods of treating acute kidney injury

Country Status (32)

Country Link
US (1) US20210283116A1 (en)
EP (1) EP3522880B1 (en)
JP (1) JP7065839B2 (en)
KR (1) KR20190062502A (en)
CN (1) CN109789117B (en)
AU (1) AU2017340760B2 (en)
BR (1) BR112019005539A2 (en)
CA (1) CA3036723A1 (en)
CO (1) CO2019004561A2 (en)
CY (1) CY1124759T1 (en)
DK (1) DK3522880T3 (en)
ES (1) ES2859487T3 (en)
HR (1) HRP20210294T1 (en)
HU (1) HUE053557T2 (en)
IL (1) IL265749A (en)
JO (1) JOP20190056B1 (en)
LT (1) LT3522880T (en)
MA (1) MA46459B1 (en)
MD (1) MD3522880T2 (en)
MX (1) MX2019003949A (en)
MY (1) MY192385A (en)
PH (1) PH12019500725A1 (en)
PL (1) PL3522880T3 (en)
PT (1) PT3522880T (en)
RS (1) RS61573B1 (en)
RU (1) RU2753607C2 (en)
SG (1) SG11201901925RA (en)
SI (1) SI3522880T1 (en)
TW (1) TWI778982B (en)
UA (1) UA124019C2 (en)
WO (1) WO2018067857A1 (en)
ZA (1) ZA201901743B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3359528T3 (en) 2015-10-07 2022-03-07 Mitobridge Inc Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof
KR102430906B1 (en) * 2016-04-13 2022-08-10 미토브리지, 인크. PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
PL3523283T3 (en) 2016-10-05 2021-12-13 Mitobridge, Inc. Crystalline and salt forms of ppar agonist compounds
EP3999060A1 (en) * 2019-07-19 2022-05-25 Vifor (International) Ag Ferroportin-inhibitors for the use in the prevention and treatment of kidney injuries
US11634387B2 (en) 2019-09-26 2023-04-25 Abionyx Pharma Sa Compounds useful for treating liver diseases
WO2022189856A1 (en) 2021-03-08 2022-09-15 Abionyx Pharma Sa Compounds useful for treating liver diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE028213T2 (en) 2003-09-19 2016-12-28 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids for use in treating PPAR-delta mediated conditions
RU2006145872A (en) * 2004-05-25 2008-06-27 Метаболекс, Инк. (Us) SUBSTITUTED TRIAZOLES AS PPAR MODULATORS AND METHODS FOR PRODUCING THEM
RU2320341C1 (en) * 2006-06-13 2008-03-27 Государственное учреждение Научный центр реконструктивной и восстановительной хирургии Восточно-Сибирского научного центра Сибирского отделения Российской Академии медицинских наук Preparation for treating acute obstruction of the upper urinary tract
KR20090071829A (en) * 2007-12-28 2009-07-02 주식회사 머젠스 Pharmaceutical composition for treatment and prevention of kidney diseases
MX2011004077A (en) 2008-10-17 2011-08-17 Metabolex Inc Methods of reducing small, dense ldl particles.
US7928067B2 (en) * 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
JP2016512201A (en) 2013-03-08 2016-04-25 アッヴィ・インコーポレイテッド How to treat acute kidney injury
JP2016520552A (en) * 2013-04-05 2016-07-14 ソーク インスティテュート フォー バイオロジカル スタディーズ PPAR agonist
EP2862574A1 (en) 2013-10-15 2015-04-22 Sanofi {4-[5-(3-chloro-phenoxy)-oxazolo[5,4 d]pyrimidin-2-yl]-2,6-dimethyl-phenoxy}-acetic acid for use in the prevention or treatment of acute kidney injury
CN105917229B (en) * 2013-12-03 2019-04-26 阿斯图特医药公司 The method and composition of diagnosis and prognosis for injury of kidney and kidney failure
US20170305894A1 (en) * 2014-10-08 2017-10-26 Mitobridge, Inc. Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof
WO2016057656A1 (en) * 2014-10-08 2016-04-14 Mitobridge, Inc. Ppar-delta agonists for use for treating mitochondrial, vascular, muscular, and demyelinating diseases
DK3359528T3 (en) * 2015-10-07 2022-03-07 Mitobridge Inc Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof

Also Published As

Publication number Publication date
AU2017340760A1 (en) 2019-03-21
EP3522880B1 (en) 2020-12-02
RU2019111421A3 (en) 2021-02-05
HRP20210294T1 (en) 2021-04-16
UA124019C2 (en) 2021-07-07
CN109789117B (en) 2022-08-23
RS61573B1 (en) 2021-04-29
JP7065839B2 (en) 2022-05-12
TW201815391A (en) 2018-05-01
RU2019111421A (en) 2020-11-06
WO2018067857A1 (en) 2018-04-12
SI3522880T1 (en) 2021-07-30
PL3522880T3 (en) 2021-08-23
AU2017340760B2 (en) 2023-07-27
DK3522880T3 (en) 2021-01-18
PH12019500725A1 (en) 2019-08-05
MY192385A (en) 2022-08-18
MD3522880T2 (en) 2021-03-31
RU2753607C2 (en) 2021-08-18
TWI778982B (en) 2022-10-01
CN109789117A (en) 2019-05-21
PT3522880T (en) 2021-02-22
KR20190062502A (en) 2019-06-05
EP3522880A1 (en) 2019-08-14
JOP20190056B1 (en) 2022-03-14
ZA201901743B (en) 2022-04-28
JP2019533660A (en) 2019-11-21
MA46459A (en) 2019-08-14
JOP20190056A1 (en) 2019-03-24
CO2019004561A2 (en) 2019-07-31
BR112019005539A2 (en) 2019-06-18
ES2859487T3 (en) 2021-10-04
MA46459B1 (en) 2021-03-31
MX2019003949A (en) 2019-06-10
CA3036723A1 (en) 2018-04-12
HUE053557T2 (en) 2021-07-28
CY1124759T1 (en) 2022-07-22
IL265749A (en) 2019-06-30
US20210283116A1 (en) 2021-09-16
LT3522880T (en) 2021-03-25

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