SG11201808717QA - Phosphaplatin liquid formulations - Google Patents

Phosphaplatin liquid formulations

Info

Publication number
SG11201808717QA
SG11201808717QA SG11201808717QA SG11201808717QA SG11201808717QA SG 11201808717Q A SG11201808717Q A SG 11201808717QA SG 11201808717Q A SG11201808717Q A SG 11201808717QA SG 11201808717Q A SG11201808717Q A SG 11201808717QA SG 11201808717Q A SG11201808717Q A SG 11201808717QA
Authority
SG
Singapore
Prior art keywords
international
pct
phosphaplatin
liquid formulations
english
Prior art date
Application number
SG11201808717QA
Inventor
Wayne Luke
Tyler Ames
Original Assignee
Phosplatin Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phosplatin Therapeutics Llc filed Critical Phosplatin Therapeutics Llc
Publication of SG11201808717QA publication Critical patent/SG11201808717QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/665Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD IIIII0110111 11111 010111110111010111111111111111011111111111111110111111 (43) International Bureau 0.. .1 j International Publication Date ..... ...,/ (10) International Publication Number WO 2017/176880 Al 12 October 2017(12.10.2017) WIPO I PCT (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/28 (2006.01) C07F 15/00 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, PCT/US2017/026139 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, 5 April 2017 (05.04.2017) KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, (25) Filing Language: English NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, (26) Publication Language: English RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, (30) Priority Data: ZA, ZM, ZW. 62/319,047 6 April 2016 (06.04.2016) US (84) Designated States (unless otherwise indicated, for every (71) Applicant: PHOSPLATIN THERAPEUTICS LLC kind [US/US]; 1350 Avenue of the Americas, New York, NY GM, of regional protection available): ARIPO (BW, GH, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, 10019 (US). TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (72) Inventors: LUKE, Wayne, D.; 208 Jennings Street, West TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Lafayette, IN 47906 (US). AMES, Tyler; 41-17 Crescent EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, St., #12c, Long Island City, NY 11101 (US). LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, (74) Agents: LIU, Wansheng Jerry et al.; Fox Rothchild LLP, GW, KM, ML, MR, NE, SN, TD, TG). 997 Lenox Drive, Building 3, Lawrenceville, NJ 08648- Published: 2311 (US). — with international search report (Art. 21(3)) (54) Title: PHOSPHAPLATIN LIQUID FORMULATIONS = 1 meta PT-112 Solutions at 2$°C./60%Ri.1 IMP% OS% 00% t q t SS% 00% 7 5% ,,,,, t ', ,,,,,,N,‘ I I I 70% 65% I Neb it , At , • -f - 4 ,- 1-1 © c3C OW days a Tse dale freafkdays 00 IN ,-1 FIG. 1 N 1-1 (57) : Pharmaceutical compositions of phosphaplatin compounds, in particular buffered stable liquid formulations of pyro - 0 dach-2 ready for use in the treatment of various cancers, and methods of preparation are disclosed. ei C
SG11201808717QA 2016-04-06 2017-04-05 Phosphaplatin liquid formulations SG11201808717QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662319047P 2016-04-06 2016-04-06
PCT/US2017/026139 WO2017176880A1 (en) 2016-04-06 2017-04-05 Phosphaplatin liquid formulations

Publications (1)

Publication Number Publication Date
SG11201808717QA true SG11201808717QA (en) 2018-11-29

Family

ID=60000715

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201808717QA SG11201808717QA (en) 2016-04-06 2017-04-05 Phosphaplatin liquid formulations

Country Status (18)

Country Link
US (1) US11154529B2 (en)
EP (1) EP3439650A4 (en)
JP (2) JP2019510831A (en)
KR (1) KR102419247B1 (en)
CN (1) CN109310663B (en)
AU (1) AU2017246883B2 (en)
BR (1) BR112018070603A2 (en)
CA (1) CA3020166A1 (en)
CL (1) CL2018002848A1 (en)
CO (1) CO2018011420A2 (en)
EA (1) EA039525B1 (en)
IL (1) IL262066A (en)
MX (1) MX2018012223A (en)
PH (1) PH12018502139A1 (en)
SG (1) SG11201808717QA (en)
TW (1) TWI798175B (en)
WO (1) WO2017176880A1 (en)
ZA (1) ZA201806530B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3565561A4 (en) * 2017-01-06 2020-08-26 Phosplatin Therapeutics LLC Phosphaplatin compounds as therapeutic agents for treatment of bone blood cancers
US20240009212A1 (en) * 2020-10-20 2024-01-11 Promontory Therapeutics Inc. Phosphaplatin compounds as therapeutic agents selectively targeting highly glycolytic tumor cells and methods thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2530279A1 (en) * 2003-06-27 2005-01-06 Akira Odani Bisphosphonate complexes
RS55714B1 (en) * 2010-06-04 2017-07-31 Univ Ohio Phosphaplatins and their use for treatment of cancers
WO2012096722A1 (en) 2011-01-12 2012-07-19 Ohio University Phosphaplatins having anti-angiogenic, anti-metastatic, and pro-apoptotic properties and uses thereof
WO2013052839A1 (en) 2011-10-05 2013-04-11 Bose Rathindra N Efficient processes for large scale preparation of phosphaplatins antitumor agents
EP2763537B1 (en) * 2011-10-05 2018-01-10 Rathindra N. Bose Efficient processes for large scale preparation of phosphaplatins antitumor agents
SI3202769T1 (en) 2012-05-24 2020-02-28 Phosplatin Therapeutics Llc Purification method for phosphaplatin compounds

Also Published As

Publication number Publication date
ZA201806530B (en) 2019-07-31
PH12018502139A1 (en) 2019-09-23
EA201892157A1 (en) 2019-04-30
IL262066A (en) 2018-11-29
JP2023014110A (en) 2023-01-26
EP3439650A4 (en) 2019-12-11
AU2017246883A1 (en) 2018-11-08
EP3439650A1 (en) 2019-02-13
TW201737920A (en) 2017-11-01
US11154529B2 (en) 2021-10-26
JP2019510831A (en) 2019-04-18
CN109310663A (en) 2019-02-05
TWI798175B (en) 2023-04-11
BR112018070603A2 (en) 2019-02-05
CL2018002848A1 (en) 2018-12-21
CA3020166A1 (en) 2017-10-12
CN109310663B (en) 2022-05-31
KR20180133889A (en) 2018-12-17
AU2017246883B2 (en) 2023-02-09
WO2017176880A1 (en) 2017-10-12
EA039525B1 (en) 2022-02-07
MX2018012223A (en) 2019-05-30
US20200323810A1 (en) 2020-10-15
KR102419247B1 (en) 2022-07-11
CO2018011420A2 (en) 2019-02-08

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