SG11201806639VA - New streptococcal proteases - Google Patents

New streptococcal proteases

Info

Publication number
SG11201806639VA
SG11201806639VA SG11201806639VA SG11201806639VA SG11201806639VA SG 11201806639V A SG11201806639V A SG 11201806639VA SG 11201806639V A SG11201806639V A SG 11201806639VA SG 11201806639V A SG11201806639V A SG 11201806639VA SG 11201806639V A SG11201806639V A SG 11201806639VA
Authority
SG
Singapore
Prior art keywords
international
pct
proteases
igg
methods
Prior art date
Application number
SG11201806639VA
Inventor
Pawel-Rammingen Ulrich Von
Christian Spoerry
Original Assignee
Genovis Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57995190&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201806639V(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genovis Ab filed Critical Genovis Ab
Publication of SG11201806639VA publication Critical patent/SG11201806639VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641—Cysteine endopeptidases (3.4.22)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 10 August 2017 (10.08.2017) WIPO I PCT (10) International Publication Number WO 2017/134274 Al 111111111111110111011111111111010111110111011101111111101011101111111111111110111111 (51) International Patent Classification: CO7K 14/36 (2006.01) Cl 2N 9/64 (2006.01) C12N 9/52 (2006.01) (21) International Application Number: PCT/EP2017/052463 (22) International Filing Date: 3 February 2017 (03.02.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 1630021-2 4 February 2016 (04.02.2016) SE (72) Inventors; and (71) Applicants : VON PAWEL-RAMMINGEN, Ulrich [SE/SE]; Johannisforsvagen 7, 91832 Savar (SE). SPO- ERRY, Christian [CH/SE]; Strombergs Vag 114, lgh -1106, 90728 Umed (SE). (74) Agent: LEWIS, Graham; 14 South Square, Gray's Inn, London Greater London WC1R 5JJ (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). ished: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) with sequence listing part of description (Rule 5.2(a)) Publ W O 20 17 / 13 427 4 Al (54) Title: NEW STREPTOCOCCAL PROTEASES (57) : The invention relates to new Streptococcal proteases designated IgdE which display IgG degrading cysteine protease activity. The invention further relates to in vitro methods of cleaving IgG using the described Streptococcal proteases, using the methods to generate Fc and Fab fragments, and using the methods to detect IgG.
SG11201806639VA 2016-02-04 2017-02-03 New streptococcal proteases SG11201806639VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1630021 2016-02-04
PCT/EP2017/052463 WO2017134274A1 (en) 2016-02-04 2017-02-03 New streptococcal proteases

Publications (1)

Publication Number Publication Date
SG11201806639VA true SG11201806639VA (en) 2018-09-27

Family

ID=57995190

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201806639VA SG11201806639VA (en) 2016-02-04 2017-02-03 New streptococcal proteases

Country Status (13)

Country Link
US (1) US20190345533A1 (en)
EP (1) EP3411389B1 (en)
JP (2) JP7123801B2 (en)
KR (1) KR20180124857A (en)
CN (1) CN109311951B (en)
AU (1) AU2017214441B2 (en)
CA (1) CA3013527C (en)
DK (1) DK3411389T3 (en)
ES (1) ES2877754T3 (en)
PL (1) PL3411389T3 (en)
PT (1) PT3411389T (en)
SG (1) SG11201806639VA (en)
WO (1) WO2017134274A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2861600T3 (en) 2014-04-04 2021-10-06 Mayo Found Medical Education & Res Immunoglobulin isotyping using precise molecular mass
US11209439B2 (en) 2015-09-24 2021-12-28 Mayo Foundation For Medical Education And Research Identification of immunoglobulin free light chains by mass spectrometry
CN109863395B (en) 2016-09-07 2023-05-23 梅约医学教育与研究基金会 Molecular weight method for identifying and monitoring cracked immunoglobulin
CN111183220B (en) 2017-05-26 2024-03-22 杰诺维斯公司 Tool for glycan analysis
US20210228738A1 (en) 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
EP3681528A4 (en) 2017-09-13 2021-07-21 Mayo Foundation for Medical Education and Research Identification and monitoring of apoptosis inhibitor of macrophage
WO2019115743A1 (en) * 2017-12-15 2019-06-20 Intervet International B.V. A vaccine for protection against streptococcus suis
JP2022550435A (en) 2019-10-04 2022-12-01 ウルトラジェニックス ファーマシューティカル インコーポレイテッド Methods for improved therapeutic use of recombinant AAV
IL294781A (en) 2020-02-14 2022-09-01 Ultragenyx Pharmaceutical Inc Gene therapy for treating cdkl5 deficiency disorder
CN115443288A (en) * 2020-06-18 2022-12-06 上海宝济药业有限公司 Mutant of immunoglobulin degrading enzyme IdeE
JP2023545731A (en) 2020-10-07 2023-10-31 アスクレピオス バイオファーマシューティカル， インコーポレイテッド Therapeutic adeno-associated virus delivery of fukutin-related protein (FKRP) to treat dystroglycanopathy disorders including limb girdle type 2I (LGMD2I)
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme
WO2022266044A1 (en) * 2021-06-15 2022-12-22 The University Of North Carolina At Chapel Hill Methods and compositions for depleting antibodies
WO2023019168A1 (en) 2021-08-11 2023-02-16 Ultragenyx Pharmaceutical Inc. Compositions and methods for treating a muscular dystrophy
WO2023088988A1 (en) * 2021-11-18 2023-05-25 Intervet International B.V. A method to produce a vaccine against streptococcus suis and the said vaccine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824074A1 (en) * 2001-04-26 2002-10-31 Pasteur Institut SEQUENCE OF THE GENOME STREPTOCOCCUS AGALACTIAE, APPLICATION TO THE DEVELOPMENT OF VACCINES, DIAGNOSIS TOOLS, AND THE IDENTIFICATION OF THERAPEUTIC TARGETS
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
WO2006069200A2 (en) 2004-12-22 2006-06-29 Novartis Vaccines And Diagnostics Inc. Group b streptococcus
CN105770871A (en) 2005-06-09 2016-07-20 汉莎医药有限公司 Use of the ides proteinase (from s. pyogenes) for treating autoimmune diseases and graft rejection
CN101889082A (en) 2007-09-14 2010-11-17 季诺维斯公司 Method and kits for dissociating Fcgamma-receptor-IgG complexes and for igg purification and detection
GB201115841D0 (en) * 2011-09-13 2011-10-26 Genovis Ab Protein and method
GB201316744D0 (en) * 2013-09-20 2013-11-06 Genovis Ab Method

Also Published As

Publication number Publication date
AU2017214441A1 (en) 2018-08-16
JP7123801B2 (en) 2022-08-23
CN109311951B (en) 2022-10-11
WO2017134274A1 (en) 2017-08-10
EP3411389B1 (en) 2021-03-24
AU2017214441B2 (en) 2021-08-19
CN109311951A (en) 2019-02-05
CA3013527C (en) 2023-09-05
US20190345533A1 (en) 2019-11-14
JP2019506866A (en) 2019-03-14
PT3411389T (en) 2021-06-28
DK3411389T3 (en) 2021-06-21
JP2022115853A (en) 2022-08-09
ES2877754T3 (en) 2021-11-17
CA3013527A1 (en) 2017-08-10
EP3411389A1 (en) 2018-12-12
PL3411389T3 (en) 2021-10-25
KR20180124857A (en) 2018-11-21

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