SG11201700874SA - Method for proliferation of pancreatic progenitor cells - Google Patents

Method for proliferation of pancreatic progenitor cells

Info

Publication number
SG11201700874SA
SG11201700874SA SG11201700874SA SG11201700874SA SG11201700874SA SG 11201700874S A SG11201700874S A SG 11201700874SA SG 11201700874S A SG11201700874S A SG 11201700874SA SG 11201700874S A SG11201700874S A SG 11201700874SA SG 11201700874S A SG11201700874S A SG 11201700874SA
Authority
SG
Singapore
Prior art keywords
proliferation
progenitor cells
pancreatic progenitor
pancreatic
cells
Prior art date
Application number
SG11201700874SA
Inventor
Yuya Kunisada
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of SG11201700874SA publication Critical patent/SG11201700874SA/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/113—Acidic fibroblast growth factor (aFGF, FGF-1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
SG11201700874SA 2014-08-04 2015-08-03 Method for proliferation of pancreatic progenitor cells SG11201700874SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014158470 2014-08-04
PCT/JP2015/072591 WO2016021734A1 (en) 2014-08-04 2015-08-03 Method for proliferation of pancreatic progenitor cells

Publications (1)

Publication Number Publication Date
SG11201700874SA true SG11201700874SA (en) 2017-03-30

Family

ID=55263991

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201700874SA SG11201700874SA (en) 2014-08-04 2015-08-03 Method for proliferation of pancreatic progenitor cells

Country Status (9)

Country Link
US (1) US10655105B2 (en)
EP (1) EP3178924B1 (en)
JP (1) JP6678107B2 (en)
KR (1) KR102416647B1 (en)
CN (1) CN106795487B (en)
AU (1) AU2015300020B2 (en)
CA (1) CA2957000C (en)
SG (1) SG11201700874SA (en)
WO (1) WO2016021734A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202014011287U1 (en) 2013-06-11 2019-02-06 The President And Fellows Of Harvard College SC-β cells and compositions for producing the cells
WO2016100898A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof
CN107614678B (en) 2014-12-18 2021-04-30 哈佛学院校长同事会 Method for producing stem cell-derived beta cells and method for using same
EP3234110B1 (en) 2014-12-18 2024-02-28 President and Fellows of Harvard College METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF
MX2018013175A (en) * 2016-04-28 2019-02-21 Takeda Pharmaceuticals Co Purification method for pancreatic precursor cells derived from pluripotent stem cells and amplification method therefor.
US20200140826A1 (en) * 2017-01-17 2020-05-07 Agency For Science, Research And Technology Maintenance and Expansion of Pancreatic Progenitor Cells
AU2018370029A1 (en) 2017-11-15 2020-07-02 Vertex Pharmaceuticals Incorporated Islet cell manufacturing compositions and methods of use
AU2019228004A1 (en) * 2018-03-02 2020-10-22 Vertex Pharmaceuticals Incorporated Methods of enhancing stem cell differentiation into beta cells
JPWO2019182157A1 (en) 2018-03-19 2021-03-18 国立大学法人京都大学 Hydrogel capsule
SG11202009855WA (en) 2018-04-23 2020-11-27 Univ Kyoto Growth inhibitor
CA3101021A1 (en) * 2018-05-31 2019-12-05 University Health Network Methods and compositions comprising tankyrase inhibitors for generating insulin producing cells
US20210292708A1 (en) 2018-08-03 2021-09-23 Kyoto University Cell production method
WO2020033879A1 (en) 2018-08-10 2020-02-13 Semma Therapeutics, Inc. Stem cell derived islet differentiation
CN112867787A (en) 2018-09-19 2021-05-28 武田药品工业株式会社 Insulin producing cells
CN112888778A (en) * 2018-10-15 2021-06-01 Cynity株式会社 Method for producing stem/progenitor cells from cells derived from an endosymbiont tissue or organ by means of a low-molecular compound
CN109749986B (en) * 2019-03-13 2021-04-02 武汉大学 Method for obtaining pancreatic precursor cells and pancreatic beta cells by differentiation of human pluripotent stem cells
CA3136401A1 (en) 2019-04-10 2020-10-15 Orizuru Therapeutics, Inc. Method for producing biological tissue-like structure
JP7385244B2 (en) * 2019-06-27 2023-11-22 国立大学法人 東京大学 Method for isolating pancreatic progenitor cells
CA3158631A1 (en) * 2019-10-21 2021-04-29 Orizuru Therapeutics, Inc. Growth inhibitor
EP4159838A1 (en) 2020-05-28 2023-04-05 Orizuru Therapeutics, Inc. Mass production method of uniform size cell aggregate
JPWO2022107877A1 (en) 2020-11-20 2022-05-27
CA3208794A1 (en) 2021-02-09 2022-08-18 Orizuru Therapeutics, Inc. Maturation agent
CN113234664A (en) * 2021-05-11 2021-08-10 澳门大学 Preparation method and application of pancreatic progenitor cells
WO2024070494A1 (en) * 2022-09-26 2024-04-04 国立大学法人京都大学 Method for producing pancreatic endoderm cells

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU780794B2 (en) * 1999-02-10 2005-04-14 Es Cell International Pte Ltd Pancreatic progenitor cells, methods and uses related thereto
US7625753B2 (en) 2003-12-23 2009-12-01 Cythera, Inc. Expansion of definitive endoderm cells
DE602007011409D1 (en) 2006-01-20 2011-02-03 Reneuron Inc METHOD FOR IMPROVED CELL PROPULATION OF PANCREAS CLEARER CELLS IN A PANCREAS CELL CULTURE
CA2742583C (en) 2008-11-04 2022-09-27 Viacyte, Inc. Stem cell aggregate suspension compositions and methods for differentiation thereof
US8008075B2 (en) * 2008-11-04 2011-08-30 Viacyte, Inc. Stem cell aggregate suspension compositions and methods of differentiation thereof
US9109245B2 (en) * 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US8932853B2 (en) 2009-12-29 2015-01-13 Takeda Pharmaceutical Company Limited Method for manufacturing pancreatic-hormone-producing cells
SG11201503045YA (en) * 2012-10-19 2015-05-28 Agency Science Tech & Res Methods of differentiating stem cells into one or more cell lineages
RU2754089C2 (en) 2013-02-06 2021-08-26 Виасайт, Инк. Cell compositions obtained from dedifferentiated reprogrammed cells
WO2015125926A1 (en) * 2014-02-21 2015-08-27 国立研究開発法人理化学研究所 Method for establishing and maintaining trophoblast stem cells

Also Published As

Publication number Publication date
CN106795487A (en) 2017-05-31
US20170233700A1 (en) 2017-08-17
KR20170031254A (en) 2017-03-20
EP3178924A1 (en) 2017-06-14
WO2016021734A1 (en) 2016-02-11
KR102416647B1 (en) 2022-07-05
CN106795487B (en) 2021-11-19
CA2957000A1 (en) 2016-02-11
EP3178924B1 (en) 2019-12-25
AU2015300020A1 (en) 2017-02-23
EP3178924A4 (en) 2018-01-24
US10655105B2 (en) 2020-05-19
JPWO2016021734A1 (en) 2017-05-18
AU2015300020B2 (en) 2021-04-08
JP6678107B2 (en) 2020-04-08
CA2957000C (en) 2023-08-01

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