SG11201606811VA - Fractionation method - Google Patents

Fractionation method

Info

Publication number
SG11201606811VA
SG11201606811VA SG11201606811VA SG11201606811VA SG11201606811VA SG 11201606811V A SG11201606811V A SG 11201606811VA SG 11201606811V A SG11201606811V A SG 11201606811VA SG 11201606811V A SG11201606811V A SG 11201606811VA SG 11201606811V A SG11201606811V A SG 11201606811VA
Authority
SG
Singapore
Prior art keywords
fractionation method
fractionation
Prior art date
Application number
SG11201606811VA
Other languages
English (en)
Inventor
Peter Stanley Gagnon
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201606811VA publication Critical patent/SG11201606811VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Water Supply & Treatment (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
SG11201606811VA 2014-02-19 2015-02-17 Fractionation method SG11201606811VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461941911P 2014-02-19 2014-02-19
PCT/SG2015/050023 WO2015126330A2 (en) 2014-02-19 2015-02-17 Fractionation method

Publications (1)

Publication Number Publication Date
SG11201606811VA true SG11201606811VA (en) 2016-09-29

Family

ID=53879206

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606811VA SG11201606811VA (en) 2014-02-19 2015-02-17 Fractionation method

Country Status (7)

Country Link
US (1) US10414794B2 (de)
EP (2) EP3348565A1 (de)
JP (1) JP2017507938A (de)
KR (1) KR20160122754A (de)
CN (1) CN105980397A (de)
SG (1) SG11201606811VA (de)
WO (1) WO2015126330A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10112971B2 (en) * 2013-02-26 2018-10-30 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers and electropositive surfaces
KR20150123796A (ko) * 2013-02-28 2015-11-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 크로마틴 결핍 세포 배양 수확물로부터의 항체들의 크로마토그래프 정제
US10253063B2 (en) * 2013-02-28 2019-04-09 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers at elevated conductivity
CN106164086A (zh) * 2014-02-27 2016-11-23 新加坡科技研究局 抗体纯化方法
CN109311937A (zh) 2016-06-15 2019-02-05 新加坡科技研究局 增强用于纯化蛋白质的色谱法的性能的方法
EP3546475A1 (de) * 2018-03-27 2019-10-02 Sanofi Volldurchflussverfahren zur reinigung rekombinanter proteine
CN111100183B (zh) * 2018-10-26 2022-07-15 中国科学院青岛生物能源与过程研究所 制备溶液渗透性目的蛋白沉淀物及从宿主细胞中分离纯化目的蛋白的方法
US20220315622A1 (en) * 2019-09-06 2022-10-06 Bia Separations D.O.O. Compositions and methods for reducing chromatin content of biological preparations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60028210T2 (de) * 1999-07-30 2007-03-08 Genentech, Inc., South San Francisco Geladene filtrationmembranen und deren verwendungen
CA2478925C (en) 2002-04-26 2016-06-07 Robert Lee Fahrner Non-affinity purification of proteins
SG188908A1 (en) * 2006-07-14 2013-04-30 Wisconsin Alumni Res Found Adsorptive membranes for trapping viruses
AU2009236305B2 (en) * 2008-04-15 2014-04-10 Grifols Therapeutics Inc. Two-stage ultrafiltration/diafiltration
WO2012142492A2 (en) * 2011-04-15 2012-10-18 University Of Georgia Research Foundation, Inc. Methods for inhibiting virus replication
US20130267690A1 (en) * 2011-09-20 2013-10-10 Bio-Rad Laboratories, Inc. Removal of virucidal agents from biomolecule preparations
EP2854980B1 (de) * 2012-05-31 2017-11-01 Agency For Science, Technology And Research Selektive bindung von biologischen zielmolekülen an festphasenureide
SG11201407809QA (en) * 2012-05-31 2014-12-30 Agency Science Tech & Res Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities
CN105026418B (zh) 2013-02-06 2019-01-11 新加坡科技研究局 蛋白质纯化方法
US10112971B2 (en) * 2013-02-26 2018-10-30 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers and electropositive surfaces
KR20150123796A (ko) * 2013-02-28 2015-11-04 에이전시 포 사이언스, 테크놀로지 앤드 리서치 크로마틴 결핍 세포 배양 수확물로부터의 항체들의 크로마토그래프 정제
KR20160012975A (ko) * 2013-06-04 2016-02-03 에이전시 포 사이언스, 테크놀로지 앤드 리서치 단백질 정제 프로세스

Also Published As

Publication number Publication date
WO2015126330A3 (en) 2015-11-05
EP3348565A1 (de) 2018-07-18
WO2015126330A2 (en) 2015-08-27
US20170057992A1 (en) 2017-03-02
EP3107927A2 (de) 2016-12-28
CN105980397A (zh) 2016-09-28
US10414794B2 (en) 2019-09-17
KR20160122754A (ko) 2016-10-24
JP2017507938A (ja) 2017-03-23
EP3107927A4 (de) 2017-08-30

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