SG11201601003PA - Process for the purification of diaminophenothiazinium compounds - Google Patents

Process for the purification of diaminophenothiazinium compounds

Info

Publication number
SG11201601003PA
SG11201601003PA SG11201601003PA SG11201601003PA SG11201601003PA SG 11201601003P A SG11201601003P A SG 11201601003PA SG 11201601003P A SG11201601003P A SG 11201601003PA SG 11201601003P A SG11201601003P A SG 11201601003PA SG 11201601003P A SG11201601003P A SG 11201601003PA
Authority
SG
Singapore
Prior art keywords
purification
diaminophenothiazinium compounds
diaminophenothiazinium
compounds
Prior art date
Application number
SG11201601003PA
Other languages
English (en)
Inventor
Malvin Eutick
Original Assignee
Eupharma Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013903099A external-priority patent/AU2013903099A0/en
Application filed by Eupharma Pty Ltd filed Critical Eupharma Pty Ltd
Publication of SG11201601003PA publication Critical patent/SG11201601003PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18[b, e]-condensed with two six-membered rings
    • C07D279/20[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
SG11201601003PA 2013-08-15 2014-08-15 Process for the purification of diaminophenothiazinium compounds SG11201601003PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2013903099A AU2013903099A0 (en) 2013-08-15 Purification method and compounds
PCT/AU2014/000807 WO2015021500A1 (en) 2013-08-15 2014-08-15 Process for the purification of diaminophenothiazinium compounds

Publications (1)

Publication Number Publication Date
SG11201601003PA true SG11201601003PA (en) 2016-03-30

Family

ID=52467850

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201601003PA SG11201601003PA (en) 2013-08-15 2014-08-15 Process for the purification of diaminophenothiazinium compounds

Country Status (14)

Country Link
US (1) US9701648B2 (es)
EP (1) EP3033331B1 (es)
JP (1) JP6111381B2 (es)
KR (1) KR101741235B1 (es)
CN (1) CN105612148B (es)
BR (1) BR112016002979A8 (es)
CA (1) CA2920505C (es)
DK (1) DK3033331T3 (es)
IL (1) IL243937A (es)
MX (1) MX354492B (es)
NZ (1) NZ630569A (es)
SG (1) SG11201601003PA (es)
TW (1) TWI629267B (es)
WO (1) WO2015021500A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3375777A1 (en) * 2017-03-15 2018-09-19 MIKROCHEM spol. s.r.o. Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide
CN112358475B (zh) * 2020-11-30 2022-09-06 西北师范大学 一种苯并吡喃鎓-吩噻嗪衍生物及其制备方法和应用
WO2023202464A1 (zh) * 2022-04-19 2023-10-26 英科隆生物技术(杭州)有限公司 一种电子媒介体的提纯方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2909520A (en) 1959-10-20 Process for making acylated
DE1886C (de) 1877-12-15 1877-12-15 Basf Ag Verfahren zur darstellung blauer farbstoffe aus dimethylanilin und anderen tertiaeren aromatischen monaminen
GB1293757A (en) 1968-10-22 1972-10-25 Paines & Byrne Ltd A nerve stain composition
GB0327672D0 (en) * 2003-11-28 2003-12-31 Photopharmica Ltd Developments in biologically active methylene blue derivatives (phenothiazines)
KR20060111536A (ko) * 2003-11-28 2006-10-27 포토파미카 리미티드 생물학적 활성 메틸렌 블루 유도체(2)의 개발
DK2322517T3 (da) 2004-09-23 2019-06-11 Wista Lab Ltd Fremgangsmåder til kemisk syntese og oprensning af diaminophenothiaziniumforbindelser med methylthioniniumchlorid (mtc)
CN101084204B (zh) * 2004-09-23 2012-12-05 卫思道制药有限公司 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法
WO2008007074A2 (en) * 2006-07-11 2008-01-17 Wista Laboratories Ltd. Methods of synthesis and/or purification of diaminophenothiazinium compounds
FR2903696B1 (fr) * 2006-07-12 2011-02-11 Provence Technologies Procede de purification de composes diaminophenothiazium
PL2673266T3 (pl) * 2011-02-11 2017-01-31 Wista Lab Ltd Fenotiazynowe sole diaminiowe i ich zastosowanie

Also Published As

Publication number Publication date
MX2016002085A (es) 2016-06-23
AU2014306354A1 (en) 2016-02-18
CN105612148B (zh) 2018-09-14
KR20160042929A (ko) 2016-04-20
EP3033331A4 (en) 2017-01-18
KR101741235B1 (ko) 2017-05-29
DK3033331T3 (da) 2018-04-30
MX354492B (es) 2018-03-07
TWI629267B (zh) 2018-07-11
CN105612148A (zh) 2016-05-25
BR112016002979A8 (pt) 2020-02-04
CA2920505A1 (en) 2015-02-19
JP2016528237A (ja) 2016-09-15
WO2015021500A1 (en) 2015-02-19
CA2920505C (en) 2018-04-03
IL243937A0 (en) 2016-04-21
EP3033331A1 (en) 2016-06-22
NZ630569A (en) 2017-06-30
US9701648B2 (en) 2017-07-11
JP6111381B2 (ja) 2017-04-05
TW201527287A (zh) 2015-07-16
EP3033331B1 (en) 2018-02-21
IL243937A (en) 2017-01-31
US20160200696A1 (en) 2016-07-14

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