SG11201506516TA - Maternal plasma transcriptome analysis by massively parallel rna sequencing - Google Patents
Maternal plasma transcriptome analysis by massively parallel rna sequencingInfo
- Publication number
- SG11201506516TA SG11201506516TA SG11201506516TA SG11201506516TA SG11201506516TA SG 11201506516T A SG11201506516T A SG 11201506516TA SG 11201506516T A SG11201506516T A SG 11201506516TA SG 11201506516T A SG11201506516T A SG 11201506516TA SG 11201506516T A SG11201506516T A SG 11201506516TA
- Authority
- SG
- Singapore
- Prior art keywords
- massively parallel
- maternal plasma
- rna sequencing
- transcriptome analysis
- parallel rna
- Prior art date
Links
- 238000003559 RNA-seq method Methods 0.000 title 1
- 230000008774 maternal effect Effects 0.000 title 1
- 238000011222 transcriptome analysis Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361770985P | 2013-02-28 | 2013-02-28 | |
| PCT/IB2014/059351 WO2014132244A1 (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201506516TA true SG11201506516TA (en) | 2015-09-29 |
Family
ID=51388739
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201609080WA SG10201609080WA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
| SG11201506516TA SG11201506516TA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201609080WA SG10201609080WA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10240199B2 (en) |
| EP (4) | EP3351643B1 (en) |
| JP (4) | JP6525894B2 (en) |
| KR (2) | KR102241051B1 (en) |
| CN (2) | CN109136364A (en) |
| AU (4) | AU2014222312B2 (en) |
| CA (2) | CA2897684C (en) |
| EA (2) | EA202190075A3 (en) |
| ES (1) | ES2670544T3 (en) |
| HK (1) | HK1253097A1 (en) |
| IL (4) | IL289547B2 (en) |
| MX (3) | MX368004B (en) |
| SG (2) | SG10201609080WA (en) |
| TW (3) | TWI641834B (en) |
| WO (1) | WO2014132244A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3351643B1 (en) * | 2013-02-28 | 2019-09-18 | The Chinese University Of Hong Kong | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
| CN105441432B (en) * | 2014-09-05 | 2019-05-28 | 天津华大基因科技有限公司 | Composition and its purposes in sequencing and variation detection |
| CN104232777B (en) * | 2014-09-19 | 2016-08-24 | 天津华大基因科技有限公司 | Determine the method and device of fetal nucleic acid content and chromosomal aneuploidy simultaneously |
| CN104232778B (en) * | 2014-09-19 | 2016-08-17 | 天津华大基因科技有限公司 | Determine the method and device of fetus haplotype and chromosomal aneuploidy simultaneously |
| US10889861B2 (en) * | 2015-06-17 | 2021-01-12 | The Translational Genomics Research Institute | Systems and methods for obtaining biological molecules from a sample |
| NL2016967B1 (en) | 2016-06-15 | 2017-12-21 | Iq Products B V | Markers and their ratio to determine the risk for early-onset preeclampsia. |
| WO2018210275A1 (en) * | 2017-05-16 | 2018-11-22 | The Chinese University Of Hong Kong | Integrative single-cell and cell-free plasma rna analysis |
| CN109280697B (en) * | 2017-07-20 | 2022-04-26 | 天昊生物医药科技（苏州）有限公司 | Method for identifying fetal genotype by using plasma free DNA of pregnant woman |
| CN110785499A (en) | 2018-05-25 | 2020-02-11 | 伊鲁米那股份有限公司 | Circulating RNA identification specific for preeclampsia |
| CN113677807A (en) | 2019-11-22 | 2021-11-19 | 因美纳有限公司 | Pre-eclampsia-specific circulating RNA markers |
| KR102326813B1 (en) * | 2020-04-20 | 2021-11-16 | 강원대학교산학협력단 | miRNA-214-3p and miRNA-1290-3p as biomarker for predicting or diagnosing pre-eclampsia |
| CA3186291A1 (en) | 2020-06-10 | 2021-12-16 | Board Of Regents, The University Of Texas System | Method for determining risk of pre-term birth |
| KR102494583B1 (en) * | 2020-11-04 | 2023-02-07 | 강원대학교산학협력단 | Method for diagnosing pre-eclampsia using ratio of expression levels of miR-31-5p and miR-1290-3p |
| KR102497167B1 (en) * | 2020-11-04 | 2023-02-08 | 강원대학교산학협력단 | Method for diagnosing pre-eclampsia using ratio of expression levels of miR-155-5p and miR-1290-3p |
| WO2023235353A2 (en) | 2022-06-03 | 2023-12-07 | Illumina, Inc. | Circulating rna biomarkers for preeclampsia |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6664056B2 (en) * | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
| CA2513292C (en) | 2003-01-17 | 2016-04-05 | The Chinese University Of Hong Kong | Circulating mrna as diagnostic markers for pregnancy-related disorders |
| AU2003263660A1 (en) * | 2003-08-29 | 2005-03-16 | Pantarhei Bioscience B.V. | Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood |
| KR20130119506A (en) * | 2004-09-24 | 2013-10-31 | 베스 이스라엘 데코니스 메디칼 센터 | Methods of diagnosing and treating complications of pregnancy |
| AU2006224971B2 (en) * | 2005-03-18 | 2009-07-02 | Boston University | A method for the detection of chromosomal aneuploidies |
| EP1859051A4 (en) | 2005-03-18 | 2009-08-05 | Univ Hong Kong Chinese | Markers for prenatal diagnosis and monitoring |
| DE102005013949A1 (en) | 2005-03-26 | 2006-09-28 | Carl Zeiss Meditec Ag | scanning device |
| US7790463B2 (en) * | 2006-02-02 | 2010-09-07 | Yale University | Methods of determining whether a pregnant woman is at risk of developing preeclampsia |
| US7901884B2 (en) | 2006-05-03 | 2011-03-08 | The Chinese University Of Hong Kong | Markers for prenatal diagnosis and monitoring |
| US20080233583A1 (en) * | 2007-02-20 | 2008-09-25 | Regents Of The University Of California | Biomarkers for preeclampsia |
| US20090029377A1 (en) | 2007-07-23 | 2009-01-29 | The Chinese University Of Hong Kong | Diagnosing fetal chromosomal aneuploidy using massively parallel genomic sequencing |
| US20100016173A1 (en) | 2008-01-30 | 2010-01-21 | Proteogenix, Inc. | Maternal serum biomarkers for detection of pre-eclampsia |
| EP4219762A1 (en) * | 2008-02-01 | 2023-08-02 | The General Hospital Corporation | Use of microvesicles in diagnosis and prognosis of medical diseases and conditions |
| US20110171650A1 (en) * | 2008-09-16 | 2011-07-14 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Gene expression related to preeclampsia |
| CN101871002B (en) * | 2009-04-22 | 2013-04-17 | 中山大学达安基因股份有限公司 | Kit for antenatally screening trisomy 21 syndrome noninvasively |
| FI3783110T3 (en) | 2009-11-05 | 2023-03-02 | Fetal genomic analysis from a maternal biological sample | |
| ES2534758T3 (en) * | 2010-01-19 | 2015-04-28 | Verinata Health, Inc. | Sequencing methods in prenatal diagnoses |
| US9260745B2 (en) * | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
| US20130316351A1 (en) | 2010-06-07 | 2013-11-28 | Osnat Ashur-Fabian | Methods and kits for diagnosing conditions related to hypoxia |
| US20120077185A1 (en) | 2010-08-06 | 2012-03-29 | Tandem Diagnostics, Inc. | Detection of genetic abnormalities and infectious disease |
| EP2426217A1 (en) | 2010-09-03 | 2012-03-07 | Centre National de la Recherche Scientifique (CNRS) | Analytical methods for cell free nucleic acids and applications |
| CN103534591B (en) | 2010-10-26 | 2016-04-06 | 利兰·斯坦福青年大学托管委员会 | The Noninvasive fetus genetic screening undertaken by sequencing analysis |
| AU2011348267A1 (en) * | 2010-12-23 | 2013-08-01 | Sequenom, Inc. | Fetal genetic variation detection |
| US8530228B2 (en) | 2010-12-28 | 2013-09-10 | Bexmart | Integrated versatile and systems preparation of specimens |
| EP3901955A1 (en) * | 2011-01-05 | 2021-10-27 | The Chinese University Of Hong Kong | Noninvasive prenatal genotyping of fetal sex chromosomes |
| EP2490027A1 (en) * | 2011-02-15 | 2012-08-22 | Roche Diagnostics GmbH | Means and methods for diagnosing pregnancy complications based on GDF-15 and PlGF/sFlt1 |
| JP5837622B2 (en) | 2011-02-24 | 2015-12-24 | ザ チャイニーズ ユニバーシティー オブ ホンコンＴｈｅ Ｃｈｉｎｅｓｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｈｏｎｇｋｏｎｇ | Molecular testing for multiple pregnancy |
| CN102286462A (en) * | 2011-06-27 | 2011-12-21 | 深圳市易瑞生物技术有限公司 | Method and kit for extracting free RNAs |
| EP3351643B1 (en) | 2013-02-28 | 2019-09-18 | The Chinese University Of Hong Kong | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
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- 2014-02-28 CA CA2897684A patent/CA2897684C/en active Active
- 2014-02-28 MX MX2015010784A patent/MX368004B/en active IP Right Grant
- 2014-02-28 AU AU2014222312A patent/AU2014222312B2/en active Active
- 2014-02-28 ES ES14757525.2T patent/ES2670544T3/en active Active
- 2014-02-28 WO PCT/IB2014/059351 patent/WO2014132244A1/en active Application Filing
- 2014-02-28 CN CN201811106855.7A patent/CN109136364A/en active Pending
- 2014-02-28 CN CN201480015402.7A patent/CN105143466B/en active Active
- 2014-02-28 EP EP14757525.2A patent/EP2961851B1/en active Active
- 2014-02-28 US US14/194,294 patent/US10240199B2/en active Active
- 2014-02-28 EP EP19190836.7A patent/EP3587588B1/en active Active
- 2014-02-28 SG SG10201609080WA patent/SG10201609080WA/en unknown
- 2014-02-28 CA CA3117788A patent/CA3117788A1/en active Pending
- 2014-02-28 SG SG11201506516TA patent/SG11201506516TA/en unknown
- 2014-02-28 EP EP21175354.6A patent/EP3910072A3/en active Pending
- 2014-02-28 KR KR1020207004904A patent/KR102241051B1/en active IP Right Grant
- 2014-02-28 JP JP2015559600A patent/JP6525894B2/en active Active
- 2014-02-28 KR KR1020157022741A patent/KR102082025B1/en active IP Right Grant
- 2014-03-03 TW TW103107127A patent/TWI641834B/en active
- 2014-03-03 TW TW107135118A patent/TWI762728B/en active
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2015
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