SG10201609080WA - Maternal plasma transcriptome analysis by massively parallel rna sequencing - Google Patents
Maternal plasma transcriptome analysis by massively parallel rna sequencingInfo
- Publication number
- SG10201609080WA SG10201609080WA SG10201609080WA SG10201609080WA SG10201609080WA SG 10201609080W A SG10201609080W A SG 10201609080WA SG 10201609080W A SG10201609080W A SG 10201609080WA SG 10201609080W A SG10201609080W A SG 10201609080WA SG 10201609080W A SG10201609080W A SG 10201609080WA
- Authority
- SG
- Singapore
- Prior art keywords
- massively parallel
- maternal plasma
- rna sequencing
- transcriptome analysis
- parallel rna
- Prior art date
Links
- 238000003559 RNA-seq method Methods 0.000 title 1
- 230000008774 maternal effect Effects 0.000 title 1
- 238000011222 transcriptome analysis Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361770985P | 2013-02-28 | 2013-02-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201609080WA true SG10201609080WA (en) | 2016-12-29 |
Family
ID=51388739
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201609080WA SG10201609080WA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
SG11201506516TA SG11201506516TA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201506516TA SG11201506516TA (en) | 2013-02-28 | 2014-02-28 | Maternal plasma transcriptome analysis by massively parallel rna sequencing |
Country Status (15)
Country | Link |
---|---|
US (2) | US10240199B2 (en) |
EP (4) | EP3587588B1 (en) |
JP (4) | JP6525894B2 (en) |
KR (2) | KR102082025B1 (en) |
CN (2) | CN109136364A (en) |
AU (4) | AU2014222312B2 (en) |
CA (2) | CA3117788A1 (en) |
EA (2) | EA037326B1 (en) |
ES (1) | ES2670544T3 (en) |
HK (1) | HK1253097A1 (en) |
IL (4) | IL289547B2 (en) |
MX (3) | MX368004B (en) |
SG (2) | SG10201609080WA (en) |
TW (3) | TWI641834B (en) |
WO (1) | WO2014132244A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109136364A (en) * | 2013-02-28 | 2019-01-04 | 香港中文大学 | Pass through extensive parallel RNA sequencing analysis mother's blood plasma transcript profile |
CN105441432B (en) * | 2014-09-05 | 2019-05-28 | 天津华大基因科技有限公司 | Composition and its purposes in sequencing and variation detection |
CN104232777B (en) * | 2014-09-19 | 2016-08-24 | 天津华大基因科技有限公司 | Determine the method and device of fetal nucleic acid content and chromosomal aneuploidy simultaneously |
CN104232778B (en) * | 2014-09-19 | 2016-08-17 | 天津华大基因科技有限公司 | Determine the method and device of fetus haplotype and chromosomal aneuploidy simultaneously |
EP3310933B1 (en) * | 2015-06-17 | 2020-11-18 | The Translational Genomics Research Institute | Methods for obtaining biological molecules from a sample |
NL2016967B1 (en) | 2016-06-15 | 2017-12-21 | Iq Products B V | Markers and their ratio to determine the risk for early-onset preeclampsia. |
EP3625357A4 (en) * | 2017-05-16 | 2021-02-24 | The Chinese University Of Hong Kong | Integrative single-cell and cell-free plasma rna analysis |
CN109280697B (en) * | 2017-07-20 | 2022-04-26 | 天昊生物医药科技(苏州)有限公司 | Method for identifying fetal genotype by using plasma free DNA of pregnant woman |
JP7334122B2 (en) | 2018-05-25 | 2023-08-28 | イルミナ インコーポレイテッド | A Circulating RNA Signature Specific to Preeclampsia |
JP2023501760A (en) | 2019-11-22 | 2023-01-19 | イルミナ インコーポレイテッド | A circulating RNA signature specific to pre-eclampsia |
KR102326813B1 (en) * | 2020-04-20 | 2021-11-16 | 강원대학교산학협력단 | miRNA-214-3p and miRNA-1290-3p as biomarker for predicting or diagnosing pre-eclampsia |
EP4165416A1 (en) | 2020-06-10 | 2023-04-19 | Board of Regents, The University of Texas System | Method for determining risk of pre-term birth |
KR102497167B1 (en) * | 2020-11-04 | 2023-02-08 | 강원대학교산학협력단 | Method for diagnosing pre-eclampsia using ratio of expression levels of miR-155-5p and miR-1290-3p |
KR102494583B1 (en) * | 2020-11-04 | 2023-02-07 | 강원대학교산학협력단 | Method for diagnosing pre-eclampsia using ratio of expression levels of miR-31-5p and miR-1290-3p |
WO2023235353A2 (en) | 2022-06-03 | 2023-12-07 | Illumina, Inc. | Circulating rna biomarkers for preeclampsia |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
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US6664056B2 (en) | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
JP4624977B2 (en) * | 2003-01-17 | 2011-02-02 | ザ チャイニーズ ユニバーシティ オブ ホンコン | Blood mRNA as a diagnostic marker for pregnancy disorders |
WO2005021793A1 (en) | 2003-08-29 | 2005-03-10 | Pantarhei Bioscience B.V. | Prenatal diagnosis of down syndrome by detection of fetal rna markers in maternal blood |
SG155257A1 (en) * | 2004-09-24 | 2009-09-30 | Beth Israel Hospital | Methods of diagnosing and treating complications of pregnancy |
JP5629051B2 (en) * | 2005-03-18 | 2014-11-19 | ザ チャイニーズ ユニバーシティー オブ ホンコンThe Chinese University Of Hongkong | Markers for prenatal diagnosis and monitoring |
JP5219516B2 (en) * | 2005-03-18 | 2013-06-26 | ザ チャイニーズ ユニバーシティー オブ ホンコン | Chromosome aneuploidy detection method |
DE102005013949A1 (en) | 2005-03-26 | 2006-09-28 | Carl Zeiss Meditec Ag | scanning device |
US7790463B2 (en) * | 2006-02-02 | 2010-09-07 | Yale University | Methods of determining whether a pregnant woman is at risk of developing preeclampsia |
US7901884B2 (en) * | 2006-05-03 | 2011-03-08 | The Chinese University Of Hong Kong | Markers for prenatal diagnosis and monitoring |
US20080233583A1 (en) * | 2007-02-20 | 2008-09-25 | Regents Of The University Of California | Biomarkers for preeclampsia |
CA2694007C (en) * | 2007-07-23 | 2019-02-26 | The Chinese University Of Hong Kong | Determining a nucleic acid sequence imbalance |
WO2009097584A1 (en) | 2008-01-30 | 2009-08-06 | Proteogenix, Inc. | Maternal serum biomarkers for detection of pre-eclampsia |
US20110053157A1 (en) * | 2008-02-01 | 2011-03-03 | The General Hospital Corporation | Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions |
US20110171650A1 (en) * | 2008-09-16 | 2011-07-14 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Gene expression related to preeclampsia |
CN101871002B (en) * | 2009-04-22 | 2013-04-17 | 中山大学达安基因股份有限公司 | Kit for antenatally screening trisomy 21 syndrome noninvasively |
HRP20230134T1 (en) | 2009-11-05 | 2023-03-31 | The Chinese University Of Hong Kong | Fetal genomic analysis from a maternal biological sample |
US9260745B2 (en) | 2010-01-19 | 2016-02-16 | Verinata Health, Inc. | Detecting and classifying copy number variation |
ES2704701T3 (en) * | 2010-01-19 | 2019-03-19 | Verinata Health Inc | New protocol for preparing sequencing libraries |
EP2576829A1 (en) | 2010-06-07 | 2013-04-10 | Osnat Ashur-Fabian | Methods and kits for diagnosing conditions related to hypoxia |
US20120077185A1 (en) | 2010-08-06 | 2012-03-29 | Tandem Diagnostics, Inc. | Detection of genetic abnormalities and infectious disease |
EP2426217A1 (en) | 2010-09-03 | 2012-03-07 | Centre National de la Recherche Scientifique (CNRS) | Analytical methods for cell free nucleic acids and applications |
CN103534591B (en) * | 2010-10-26 | 2016-04-06 | 利兰·斯坦福青年大学托管委员会 | The Noninvasive fetus genetic screening undertaken by sequencing analysis |
CN103384725A (en) | 2010-12-23 | 2013-11-06 | 塞昆纳姆股份有限公司 | Fetal genetic variation detection |
US8530228B2 (en) | 2010-12-28 | 2013-09-10 | Bexmart | Integrated versatile and systems preparation of specimens |
JP6105485B2 (en) * | 2011-01-05 | 2017-04-05 | ザ・チャイニーズ・ユニバーシティー・オブ・ホンコンThe Chinese University Of Hong Kong | Noninvasive prenatal identification of fetal sex chromosome genotypes |
EP2490027A1 (en) * | 2011-02-15 | 2012-08-22 | Roche Diagnostics GmbH | Means and methods for diagnosing pregnancy complications based on GDF-15 and PlGF/sFlt1 |
CA3160848A1 (en) | 2011-02-24 | 2013-03-28 | The Chinese University Of Hong Kong | Molecular testing of multiple pregnancies |
CN102286462A (en) * | 2011-06-27 | 2011-12-21 | 深圳市易瑞生物技术有限公司 | Method and kit for extracting free RNAs |
CN109136364A (en) * | 2013-02-28 | 2019-01-04 | 香港中文大学 | Pass through extensive parallel RNA sequencing analysis mother's blood plasma transcript profile |
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2014
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- 2014-02-28 EA EA201591582A patent/EA037326B1/en unknown
- 2014-02-28 IL IL289547A patent/IL289547B2/en unknown
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- 2014-02-28 KR KR1020157022741A patent/KR102082025B1/en active IP Right Grant
- 2014-02-28 KR KR1020207004904A patent/KR102241051B1/en active IP Right Grant
- 2014-02-28 EP EP18160528.8A patent/EP3351643B1/en active Active
- 2014-02-28 MX MX2015010784A patent/MX368004B/en active IP Right Grant
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- 2014-02-28 AU AU2014222312A patent/AU2014222312B2/en active Active
- 2014-03-03 TW TW103107127A patent/TWI641834B/en active
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2018
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2019
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