SG11201407328TA - Compositions and methods for the treatment of moderate to severe pain - Google Patents

Compositions and methods for the treatment of moderate to severe pain

Info

Publication number
SG11201407328TA
SG11201407328TA SG11201407328TA SG11201407328TA SG11201407328TA SG 11201407328T A SG11201407328T A SG 11201407328TA SG 11201407328T A SG11201407328T A SG 11201407328TA SG 11201407328T A SG11201407328T A SG 11201407328TA SG 11201407328T A SG11201407328T A SG 11201407328TA
Authority
SG
Singapore
Prior art keywords
international
pain
compositions
moderate
publication
Prior art date
Application number
SG11201407328TA
Inventor
Mahesh Kandula
Original Assignee
Cellix Bio Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellix Bio Private Ltd filed Critical Cellix Bio Private Ltd
Publication of SG11201407328TA publication Critical patent/SG11201407328TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 9 January 2014 (09.01.2014) WIPOIPCT (10) International Publication Number WO 2014/006529 A3 (51) International Patent Classification: C07C 25/08 (2006.01) A61P 29/00 (2006.01) A61K31/136 (2006.01) A61P 25/04 (2006.01) A61K31/02 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: PCT/IB2013/055146 23 June 2013 (23.06.2013) English (26) Publication Language: (30) Priority Data: 2682/CHE/2012 3 July 2012 (03.07.2012) English IN (72) Inventor; and (71) Applicant : KANDULA, Mahesh [IN/IN]; Door No. 11- 61, East Godavari Dist, Andhra Pradesh, India, G.medapadu 533434 (IN). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) (88) Date of publication of the international search report: 24 April 2014 o\ CJ o o o CJ O & (54) Title: COMPOSITIONS AND METHODS FOR THE TREATMENT OF MODERATE TO SEVERE PAIN (57) Abstract: The invention relates to the compounds of formula 1 or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof The pharmaceutical compositions comprising art effective amount of com­ pounds of formula I; and methods for treating or preventing moderate to severe pain, may he formulated for oral, buccal, rectal, top - ical, transdermal, transmucosal, intravenous, parenieral adminisiration, syrup, or injection. Such compositions may be used to treat - ment of muscle pain, spasticity, neuropathic pain, fibromyalgia, postoperative pain,.muscle spasticity, headache, chronic pain, sub- chronic pain and local pain.
SG11201407328TA 2012-07-03 2013-06-23 Compositions and methods for the treatment of moderate to severe pain SG11201407328TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2682CH2012 2012-07-03
PCT/IB2013/055146 WO2014006529A2 (en) 2012-07-03 2013-06-23 Compositions and methods for the treatment of moderate to severe pain

Publications (1)

Publication Number Publication Date
SG11201407328TA true SG11201407328TA (en) 2014-12-30

Family

ID=54188020

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201407328TA SG11201407328TA (en) 2012-07-03 2013-06-23 Compositions and methods for the treatment of moderate to severe pain

Country Status (8)

Country Link
EP (1) EP2870130A4 (en)
JP (1) JP2015527309A (en)
CN (1) CN104583162A (en)
AU (1) AU2013285126A1 (en)
CA (1) CA2873018A1 (en)
SG (1) SG11201407328TA (en)
WO (1) WO2014006529A2 (en)
ZA (1) ZA201408057B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2873094A1 (en) * 2012-05-07 2013-11-14 Cellixbio Private Limited Prodrugs of anti-platelet agents
WO2016046674A1 (en) * 2014-09-28 2016-03-31 Mohan M Alapati Compositions and methods for the treatment of moderate to severe pain
CN105037241B (en) * 2015-06-19 2018-02-23 上海上药新亚药业有限公司 The synthesis technique of 1 (2,6 dichlorophenyl) 2 indolones
CN111116391A (en) * 2019-12-17 2020-05-08 浙江工业大学 Preparation method of sodium 2- [ (2, 6-dichlorophenyl) amino ] phenylacetate

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137301C (en) * 1966-03-30
AU514991B2 (en) * 1976-05-26 1981-03-12 Commonwealth Of Australia, The Pharmaceutical compositions containing antiinflammatory analgesic compounds
LU78106A1 (en) * 1977-05-11 1979-05-23 Ciba Geigy Ag PROCESS FOR PREPARING NEW SUBSTITUTED PHENYL ACID AMIDE COMPOUNDS
JPS5412340A (en) * 1977-06-27 1979-01-30 Daito Koeki Process for preparing phenylacetate derivative
NL8602767A (en) * 1986-10-31 1988-05-16 Gantax Nv ORGANIC ACID ANHYDRIDE, AND A PHARMACEUTICAL PREPARATION BASED ON A PRODRUG.
MY118354A (en) * 1995-05-01 2004-10-30 Scarista Ltd 1,3-propane diol derivatives as bioactive compounds
JPH1143467A (en) * 1997-05-14 1999-02-16 Ikeda Mohandou:Kk Fatty acid glyceride derivative and glyceride derivative, and their production
US6429223B1 (en) * 2000-06-23 2002-08-06 Medinox, Inc. Modified forms of pharmacologically active agents and uses therefor
CN101868443A (en) * 2007-09-20 2010-10-20 特拉维夫大学拉莫特有限公司 N-phenyl anthranilic acid derivatives and uses thereof
US20090082450A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched diclofenac
CN101186583B (en) * 2007-12-20 2011-05-11 吉林大学 Methyl 2-(2-(2,6-dichlorophenylamino)phenyl)acetate and its synthesizing method and application
BRPI0901298A2 (en) * 2009-04-06 2011-01-04 Ems Sa phthalimide derivatives of nonsteroidal antiinflammatory compounds and / or modulators of tnf- (alpha), process for obtaining them, pharmaceutical compositions containing them and their uses in the treatment of inflammatory diseases
US9525998B2 (en) * 2012-01-06 2016-12-20 Qualcomm Incorporated Wireless display with multiscreen service
JP6097766B2 (en) * 2012-01-27 2017-03-15 インターデイジタル パテント ホールディングス インコーポレイテッド System and / or method for providing EPDCCH in a multi-carrier based and / or pseudo matching network
CA2873094A1 (en) * 2012-05-07 2013-11-14 Cellixbio Private Limited Prodrugs of anti-platelet agents
JP2015519333A (en) * 2012-05-07 2015-07-09 セリックスビオ プライヴェート リミテッド Compositions and methods for the treatment of neurological disorders
SG11201407309XA (en) * 2012-05-08 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of epilepsy
SG11201407314XA (en) * 2012-05-08 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of diabetes
JP2015533114A (en) * 2012-05-08 2015-11-19 セリックスビオ プライヴェート リミテッド Compositions and methods for the treatment of neurological disorders
EP2847175A4 (en) * 2012-05-08 2016-04-20 Cellix Bio Private Ltd Compositions and methods for suppression of carbonic anhydrase activity

Also Published As

Publication number Publication date
CA2873018A1 (en) 2014-01-09
CN104583162A (en) 2015-04-29
WO2014006529A2 (en) 2014-01-09
EP2870130A2 (en) 2015-05-13
ZA201408057B (en) 2016-03-30
JP2015527309A (en) 2015-09-17
AU2013285126A1 (en) 2014-11-27
EP2870130A4 (en) 2015-12-02
WO2014006529A3 (en) 2014-04-24

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