SG10202006685XA - Treatment of Cancers Using Anti-NKG2A Agents - Google Patents

Treatment of Cancers Using Anti-NKG2A Agents

Info

Publication number
SG10202006685XA
SG10202006685XA SG10202006685XA SG10202006685XA SG10202006685XA SG 10202006685X A SG10202006685X A SG 10202006685XA SG 10202006685X A SG10202006685X A SG 10202006685XA SG 10202006685X A SG10202006685X A SG 10202006685XA SG 10202006685X A SG10202006685X A SG 10202006685XA
Authority
SG
Singapore
Prior art keywords
cancers
treatment
nkg2a
agents
nkg2a agents
Prior art date
Application number
SG10202006685XA
Inventor
Pascale Andre
Mathieu Blery
Caroline Soulas
Nicolaï Wagtmann
Original Assignee
Innate Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innate Pharma filed Critical Innate Pharma
Publication of SG10202006685XA publication Critical patent/SG10202006685XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
SG10202006685XA 2014-10-23 2015-10-23 Treatment of Cancers Using Anti-NKG2A Agents SG10202006685XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462067642P 2014-10-23 2014-10-23

Publications (1)

Publication Number Publication Date
SG10202006685XA true SG10202006685XA (en) 2020-08-28

Family

ID=54347541

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202006685XA SG10202006685XA (en) 2014-10-23 2015-10-23 Treatment of Cancers Using Anti-NKG2A Agents
SG11201701388UA SG11201701388UA (en) 2014-10-23 2015-10-23 Treatment of cancers using anti-nkg2a agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201701388UA SG11201701388UA (en) 2014-10-23 2015-10-23 Treatment of cancers using anti-nkg2a agents

Country Status (11)

Country Link
US (2) US10329348B2 (en)
EP (2) EP3659625A1 (en)
JP (1) JP6889660B2 (en)
KR (1) KR102598068B1 (en)
CN (1) CN107073116A (en)
AU (1) AU2015334886B9 (en)
CA (1) CA2959841A1 (en)
IL (1) IL250677B (en)
RU (1) RU2721271C2 (en)
SG (2) SG10202006685XA (en)
WO (1) WO2016062851A1 (en)

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SG10202006685XA (en) 2014-10-23 2020-08-28 Innate Pharma Treatment of Cancers Using Anti-NKG2A Agents
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EP3652207A1 (en) * 2017-07-10 2020-05-20 Innate Pharma Combination therapy using antibody to human siglec-9 and antibody to human nkg2a for treating cancer
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AR126001A1 (en) * 2021-06-01 2023-08-30 Symphogen As ANTI-NKG2A ANTIBODIES AND COMPOSITIONS

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Also Published As

Publication number Publication date
KR102598068B1 (en) 2023-11-06
US20190322744A1 (en) 2019-10-24
SG11201701388UA (en) 2017-03-30
JP6889660B2 (en) 2021-06-18
CA2959841A1 (en) 2016-04-28
US10329348B2 (en) 2019-06-25
RU2017107559A (en) 2018-11-27
IL250677B (en) 2021-03-25
AU2015334886B9 (en) 2021-07-08
EP3659625A1 (en) 2020-06-03
AU2015334886A1 (en) 2017-03-16
AU2015334886B2 (en) 2021-06-10
RU2017107559A3 (en) 2019-04-15
US11225519B2 (en) 2022-01-18
IL250677A0 (en) 2017-03-30
US20170313773A1 (en) 2017-11-02
KR20170070076A (en) 2017-06-21
RU2721271C2 (en) 2020-05-18
EP3209687A1 (en) 2017-08-30
CN107073116A (en) 2017-08-18
JP2017537069A (en) 2017-12-14
WO2016062851A1 (en) 2016-04-28

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