SG10201908265UA - L-fabp immunoassay method and assay reagent used in said method - Google Patents

L-fabp immunoassay method and assay reagent used in said method

Info

Publication number
SG10201908265UA
SG10201908265UA SG10201908265UA SG10201908265UA SG 10201908265U A SG10201908265U A SG 10201908265UA SG 10201908265U A SG10201908265U A SG 10201908265UA SG 10201908265U A SG10201908265U A SG 10201908265UA
Authority
SG
Singapore
Prior art keywords
fabp
reagent used
assay reagent
sample
antibody
Prior art date
Application number
Inventor
Koji Kobayashi
Takuji Matsumoto
Mitsuaki Yamamoto
Original Assignee
Sekisui Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sekisui Medical Co Ltd filed Critical Sekisui Medical Co Ltd
Publication of SG10201908265UA publication Critical patent/SG10201908265UA/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/02—Monocyclic hydrocarbons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L-FABP IMMUNOASSAY METHOD AND ASSAY REAGENT USED IN SAID METHOD A problem to be solved by the invention is to provide an immunological measurement method for L-FABP in a sample using an anti-L-FABP antibody having a detection sensitivity equal to or greater than that of an existing pharmaceutical product for in-vitro diagnosis and having a favorable correlation. The problem is solved by a method of detecting L-FABP (liver-type fatty acid binding protein) in a sample with an anti-L-FABP antibody, comprising the step of bringing an anti-L-FABP antibody and a compound having a partial structure of NH-C=N- and a cyclic structure in a molecule into contact with a sample suspected of containing L-FABP. FIG. 1 61
SG10201908265U 2015-02-25 2016-02-25 L-fabp immunoassay method and assay reagent used in said method SG10201908265UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2015034951 2015-02-25

Publications (1)

Publication Number Publication Date
SG10201908265UA true SG10201908265UA (en) 2019-10-30

Family

ID=56789567

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201706790TA SG11201706790TA (en) 2015-02-25 2016-02-25 L-fabp immunoassay method and assay reagent used in said method
SG10201908265U SG10201908265UA (en) 2015-02-25 2016-02-25 L-fabp immunoassay method and assay reagent used in said method

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201706790TA SG11201706790TA (en) 2015-02-25 2016-02-25 L-fabp immunoassay method and assay reagent used in said method

Country Status (9)

Country Link
US (1) US20180088118A1 (en)
EP (2) EP3264083B1 (en)
JP (1) JP6660932B2 (en)
KR (1) KR102431142B1 (en)
CN (2) CN113671193A (en)
CA (1) CA2977759A1 (en)
SG (2) SG11201706790TA (en)
TW (1) TW201702596A (en)
WO (1) WO2016136863A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018173334A (en) * 2017-03-31 2018-11-08 株式会社シマ研究所 Method for immunological measurement and reagent kit used for the same
CN108445222A (en) * 2018-02-01 2018-08-24 浙江艾明德生物科技有限公司 A kind of kit and preparation method quantitatively detecting cardic fatty acid binding protein
JP6581273B1 (en) * 2018-09-28 2019-09-25 シミックホールディングス株式会社 Method for quantifying liver-type fatty acid binding protein, kit for quantification thereof, method for testing renal disease, test kit for the same, and companion diagnostic agent
SG11202110318YA (en) * 2019-03-29 2021-10-28 Sekisui Medical Co Ltd Immunoassay reagent and immunoassay method
CN112505000A (en) * 2020-11-19 2021-03-16 中国科学院生态环境研究中心 Novel method for quantifying CB (platelet-rich protein) in biological sample based on polyacrylamide gel electrophoresis

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
JP3259768B2 (en) 1997-11-26 2002-02-25 田辺製薬株式会社 Testing methods for kidney disease
TW562926B (en) * 1997-11-26 2003-11-21 Tanabe Seiyaku Co Method for testing renal diseases
JPH11281646A (en) * 1998-03-30 1999-10-15 Dai Ichi Pure Chem Co Ltd Immunological measuring method
JP4496168B2 (en) * 2003-07-28 2010-07-07 株式会社リバース・プロテオミクス研究所 Method for removing non-specific substances
WO2007074860A1 (en) * 2005-12-28 2007-07-05 Sekisui Medical Co., Ltd. Reagent for measuring aggregation and method of measuring aggregation
EP2006682B1 (en) * 2006-03-22 2014-06-04 DS Pharma Biomedical Co., Ltd. Diagnosis of acute enteritis by determination of intestinal fatty acid-binding protein in the blood
EP2042870A1 (en) * 2007-09-28 2009-04-01 Fujifilm Corporation Method of high sensitive immunoassay
JP5359885B2 (en) 2007-12-21 2013-12-04 コニカミノルタ株式会社 Nephropathy test method and test kit using the same
JP5565607B2 (en) * 2009-07-15 2014-08-06 国立大学法人 東京大学 Prognosis diagnosis method and sepsis diagnosis kit for sepsis or multiple organ failure
CA2800458A1 (en) * 2010-06-15 2011-12-22 F. Hoffmann-La Roche Ag Prediction and recognition of acute kidney injury after surgery
EP2399885A1 (en) * 2010-06-22 2011-12-28 Ulrich Dietz Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification
CN101921845B (en) * 2010-09-18 2013-01-02 吉林大学 Molecular marker of liver fatty acid binding protein (L-FABP) as pork quality character and application thereof
EP2568291A1 (en) * 2011-09-07 2013-03-13 Roche Diagnostics GmbH L-FABP based diagnosis of kidney injury after an acute event or after a surgical intervention
CN102628864B (en) * 2011-12-30 2014-08-13 北京九强生物技术股份有限公司 Kit for determining heart-type fatty acid binding protein in serum or urine by latex enhanced turbidimetric immunoassay
JP6091158B2 (en) 2012-10-23 2017-03-08 デンカ生研株式会社 Method to increase sensitivity of immunoassay system by pretreatment of urine with denaturant
CN103941019A (en) * 2014-04-10 2014-07-23 瑞莱生物工程（深圳）有限公司 Immunofluorescence test paper strip for rapidly and quantitatively detecting L-FABP (Liver-Fatty Acid Binding Protein) and preparation method thereof
US20180246090A1 (en) * 2015-02-25 2018-08-30 Sekisui Medical Co., Ltd. Immunoassay method and assay reagent used in said method

Also Published As

Publication number Publication date
EP3264083A4 (en) 2018-07-18
EP3564673A1 (en) 2019-11-06
JP6660932B2 (en) 2020-03-11
US20180088118A1 (en) 2018-03-29
JPWO2016136863A1 (en) 2017-11-30
WO2016136863A1 (en) 2016-09-01
EP3264083B1 (en) 2019-09-25
TW201702596A (en) 2017-01-16
EP3564673B1 (en) 2020-08-05
EP3264083A1 (en) 2018-01-03
KR20170118858A (en) 2017-10-25
CA2977759A1 (en) 2016-09-01
SG11201706790TA (en) 2017-09-28
CN107533053A (en) 2018-01-02
CN113671193A (en) 2021-11-19
KR102431142B1 (en) 2022-08-11

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