SG10201706045RA - Pertuzumab variants and evaluation thereof - Google Patents

Pertuzumab variants and evaluation thereof

Info

Publication number
SG10201706045RA
SG10201706045RA SG10201706045RA SG10201706045RA SG10201706045RA SG 10201706045R A SG10201706045R A SG 10201706045RA SG 10201706045R A SG10201706045R A SG 10201706045RA SG 10201706045R A SG10201706045R A SG 10201706045RA SG 10201706045R A SG10201706045R A SG 10201706045RA
Authority
SG
Singapore
Prior art keywords
evaluation
pertuzumab variants
pertuzumab
variants
Prior art date
Application number
SG10201706045RA
Inventor
Lynn A Gennaro
Yung-Hsiang Kao
Yonghua Zhang
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50694078&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201706045R(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG10201706045RA publication Critical patent/SG10201706045RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44747Composition of gel or of carrier mixture
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
SG10201706045RA 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof SG10201706045RA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361812603P 2013-04-16 2013-04-16

Publications (1)

Publication Number Publication Date
SG10201706045RA true SG10201706045RA (en) 2017-08-30

Family

ID=50694078

Family Applications (3)

Application Number Title Priority Date Filing Date
SG10201706045RA SG10201706045RA (en) 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof
SG10201911353WA SG10201911353WA (en) 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof
SG11201508536PA SG11201508536PA (en) 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201911353WA SG10201911353WA (en) 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof
SG11201508536PA SG11201508536PA (en) 2013-04-16 2014-04-15 Pertuzumab variants and evaluation thereof

Country Status (25)

Country Link
US (7) US9815904B2 (en)
EP (2) EP2986643A2 (en)
JP (2) JP2016522176A (en)
KR (2) KR20150143649A (en)
CN (1) CN105121471A (en)
AR (1) AR095863A1 (en)
AU (3) AU2014254086B2 (en)
BR (1) BR112015024926A2 (en)
CA (2) CA3071678A1 (en)
CL (3) CL2015003049A1 (en)
CR (1) CR20150576A (en)
EA (1) EA201591643A1 (en)
HK (1) HK1211948A1 (en)
IL (2) IL241103B (en)
MA (1) MA38567A1 (en)
MX (2) MX368259B (en)
MY (1) MY173295A (en)
NZ (2) NZ712012A (en)
PE (2) PE20151769A1 (en)
PH (1) PH12015502382A1 (en)
RU (2) RU2737727C2 (en)
SG (3) SG10201706045RA (en)
TW (1) TWI554284B (en)
WO (1) WO2014172371A2 (en)
ZA (1) ZA201506594B (en)

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JP7259778B2 (en) 2020-01-31 2023-04-18 トヨタ自動車株式会社 Vehicles and automated driving systems
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Publication number Publication date
PE20211214A1 (en) 2021-07-05
AU2014254086A1 (en) 2015-10-08
CA3071678A1 (en) 2014-10-23
CL2017002445A1 (en) 2018-03-16
US20230047103A1 (en) 2023-02-16
PE20151769A1 (en) 2015-12-11
TWI554284B (en) 2016-10-21
AU2018241141A1 (en) 2018-10-25
US20180037661A1 (en) 2018-02-08
MY173295A (en) 2020-01-14
IL241103A0 (en) 2015-11-30
IL275398A (en) 2020-07-30
SG11201508536PA (en) 2015-11-27
CL2015003049A1 (en) 2016-06-10
EP3800204A1 (en) 2021-04-07
TW201442725A (en) 2014-11-16
CR20150576A (en) 2015-11-20
PH12015502382A1 (en) 2016-02-22
US20180037660A1 (en) 2018-02-08
AU2018241141B2 (en) 2019-11-07
ZA201506594B (en) 2018-11-28
WO2014172371A2 (en) 2014-10-23
CN105121471A (en) 2015-12-02
AU2019253804A1 (en) 2019-11-14
AR095863A1 (en) 2015-11-18
CA2907776C (en) 2020-04-14
IL241103B (en) 2020-07-30
HK1211948A1 (en) 2016-06-03
JP2020015719A (en) 2020-01-30
MX2015013898A (en) 2016-07-08
MA38567A1 (en) 2017-09-29
RU2019115089A (en) 2019-06-11
MX2019005151A (en) 2022-06-27
US20190345258A1 (en) 2019-11-14
US9969811B2 (en) 2018-05-15
MX368259B (en) 2019-09-25
BR112015024926A2 (en) 2017-10-10
JP2016522176A (en) 2016-07-28
KR20200085942A (en) 2020-07-15
US9815904B2 (en) 2017-11-14
NZ712012A (en) 2020-04-24
SG10201911353WA (en) 2020-02-27
NZ751877A (en) 2020-04-24
CL2019002244A1 (en) 2019-11-29
RU2015141520A (en) 2017-05-22
WO2014172371A3 (en) 2015-01-08
CA2907776A1 (en) 2014-10-23
US20140308277A1 (en) 2014-10-16
RU2737727C2 (en) 2020-12-02
US20180037662A1 (en) 2018-02-08
US20200157238A1 (en) 2020-05-21
EP2986643A2 (en) 2016-02-24
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EA201591643A1 (en) 2016-02-29
KR20150143649A (en) 2015-12-23

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