SG10201606970UA - Chromatographic isolation of cells and other complex biological materials - Google Patents

Chromatographic isolation of cells and other complex biological materials

Info

Publication number
SG10201606970UA
SG10201606970UA SG10201606970UA SG10201606970UA SG10201606970UA SG 10201606970U A SG10201606970U A SG 10201606970UA SG 10201606970U A SG10201606970U A SG 10201606970UA SG 10201606970U A SG10201606970U A SG 10201606970UA SG 10201606970U A SG10201606970U A SG 10201606970UA
Authority
SG
Singapore
Prior art keywords
cells
biological materials
complex biological
chromatographic isolation
chromatographic
Prior art date
Application number
SG10201606970UA
Other languages
English (en)
Inventor
Herbert Stadler
Original Assignee
Juno Therapeutics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juno Therapeutics Gmbh filed Critical Juno Therapeutics Gmbh
Publication of SG10201606970UA publication Critical patent/SG10201606970UA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3823Affinity chromatography of other types, e.g. avidin, streptavidin, biotin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/7051T-cell receptor (TcR)-CD3 complex
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70517CD8

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG10201606970UA 2012-02-23 2013-02-25 Chromatographic isolation of cells and other complex biological materials SG10201606970UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261602150P 2012-02-23 2012-02-23

Publications (1)

Publication Number Publication Date
SG10201606970UA true SG10201606970UA (en) 2016-10-28

Family

ID=47891608

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201404991YA SG11201404991YA (en) 2012-02-23 2013-02-25 Chromatographic isolation of cells and other complex biological materials
SG10201606970UA SG10201606970UA (en) 2012-02-23 2013-02-25 Chromatographic isolation of cells and other complex biological materials

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201404991YA SG11201404991YA (en) 2012-02-23 2013-02-25 Chromatographic isolation of cells and other complex biological materials

Country Status (11)

Country Link
US (3) US10228312B2 (zh)
EP (1) EP2817625A2 (zh)
JP (4) JP6362543B2 (zh)
CN (2) CN106940268B (zh)
AU (3) AU2013224027B2 (zh)
CA (1) CA2865033C (zh)
HK (1) HK1202335A1 (zh)
IN (1) IN2014DN06475A (zh)
RU (1) RU2746407C1 (zh)
SG (2) SG11201404991YA (zh)
WO (1) WO2013124474A2 (zh)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9637719B2 (en) 2013-12-06 2017-05-02 Douglas T. Gjerde Devices and methods for purification of biological cells
AU2013224027B2 (en) * 2012-02-23 2019-01-24 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
CN105980402B (zh) 2013-12-20 2021-06-15 弗雷德哈钦森癌症研究中心 带标签的嵌合效应分子及其受体
EP3126027A4 (en) * 2014-04-03 2017-11-01 Douglas T. Gjerde Devices and methods for purification, detection and use of biological cells
RS62471B1 (sr) 2014-04-16 2021-11-30 Juno Therapeutics Gmbh Metode, kompleti i uređaji za proširenje populacije ćelija
JP6759187B2 (ja) 2014-04-23 2020-09-23 ジュノー セラピューティクス インコーポレイテッド 養子療法用の免疫細胞集団を単離、培養、および遺伝子操作するための方法
CA2945414C (en) * 2014-04-30 2023-05-09 Iba Gmbh Method of isolating a target cell
EP2955521A1 (en) * 2014-06-11 2015-12-16 Centre Hospitalier Universitaire Vaudois (CHUV) Methods for separating cells
TWI787903B (zh) * 2014-11-05 2022-12-21 美商奇諾治療有限公司 用於轉導作用及細胞處理之方法
DE202014105965U1 (de) 2014-12-10 2015-01-26 Cell.Copedia GmbH Spritzengehäuse zum Pipettieren eines biologischen Materials mit integrierten Membranen
WO2016166568A1 (en) 2015-04-16 2016-10-20 Juno Therapeutics Gmbh Methods, kits and apparatus for expanding a population of cells
EP3288570A4 (en) 2015-04-29 2018-11-21 Fred Hutchinson Cancer Research Center Modified stem cells and uses thereof
CN105606815A (zh) * 2015-05-18 2016-05-25 烟台载通生物技术有限公司 一种用于免疫检测的多单元装置
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
RU2761555C2 (ru) 2015-10-22 2021-12-09 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
GB201521784D0 (en) * 2015-12-10 2016-01-27 Univ Birmingham Cell purification
EP3491024A2 (en) 2016-07-29 2019-06-05 Juno Therapeutics, Inc. Anti-idiotypic antibodies against anti-cd19 antibodies
US10294454B2 (en) 2016-08-24 2019-05-21 General Electric Company Methods and kits for cell activation
WO2018112557A1 (en) * 2016-12-23 2018-06-28 Altnia Operations Pty Ltd Methods and compositions for purification or isolation of microvesicles and exosomes
EP3571221A2 (en) 2017-01-20 2019-11-27 Juno Therapeutics GmbH Cell surface conjugates and related cell compositions and methods
EP3615653A1 (en) * 2017-04-27 2020-03-04 Juno Therapeutics GmbH Oligomeric particle reagents and methods of use thereof
EP3661528A1 (en) 2017-07-29 2020-06-10 Juno Therapeutics, Inc. Reagents for expanding cells expressing recombinant receptors
CA3070579A1 (en) 2017-08-09 2019-02-14 Juno Therapeutics, Inc. Methods for producing genetically engineered cell compositions and related compositions
MX2020005908A (es) 2017-12-08 2020-10-07 Juno Therapeutics Inc Proceso para producir una composicion de celulas t modificadas.
WO2019133842A1 (en) * 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Purification and labeling of extracellular vesicles using a mixed mode resin composition
EP3824088A1 (en) * 2018-07-17 2021-05-26 University of Washington Compositions and methods related to aptamer-based reversible cell selection
SG11202101204TA (en) 2018-08-09 2021-03-30 Juno Therapeutics Inc Processes for generating engineered cells and compositions thereof
SG11202102108QA (en) 2018-09-11 2021-04-29 Juno Therapeutics Inc Methods for mass spectrometry analysis of engineered cell compositions
BR112021008133A2 (pt) 2018-10-31 2021-10-05 Juno Therapeutics Gmbh Métodos para seleção e estimulação de células e aparelhos para os mesmos
MX2021005021A (es) 2018-11-06 2021-08-11 Juno Therapeutics Inc Proceso para producir celulas t geneticamente modificadas.
JP2022535380A (ja) 2019-06-07 2022-08-08 ジュノー セラピューティクス インコーポレイテッド 自動化t細胞培養
WO2020260949A2 (en) * 2019-06-27 2020-12-30 Bioimmunate Technologies Ltd. Devices, systems, and methods for removal of components from biological fluids
KR20220052992A (ko) * 2019-08-30 2022-04-28 프로디자인 소닉스, 인크. 다중 표적 수용체를 위한 음향 친화성 세포 선택
WO2021041994A2 (en) 2019-08-30 2021-03-04 Juno Therapeutics, Inc. Machine learning methods for classifying cells
AU2020377043A1 (en) 2019-10-30 2022-06-02 Juno Therapeutics Gmbh Cell selection and/or stimulation devices and methods of use
WO2021118873A1 (en) * 2019-12-09 2021-06-17 St. Jude Children's Research Hospital, Inc. Method for preparing cd7-negative, cd3-positive t cells
AU2021214142A1 (en) 2020-01-28 2022-09-08 Juno Therapeutics, Inc. Methods for T cell transduction
CA3163761C (en) * 2020-01-31 2023-07-11 Herbert Stadler Methods of isolating a biological entity
US20230087953A1 (en) 2020-02-12 2023-03-23 Juno Therapeutics, Inc. Bcma-directed chimeric antigen receptor t cell compositions and methods and uses thereof
EP4103204A1 (en) 2020-02-12 2022-12-21 Juno Therapeutics, Inc. Cd19-directed chimeric antigen receptor t cell compositions and methods and uses thereof
JP2023526278A (ja) 2020-05-13 2023-06-21 ジュノー セラピューティクス インコーポレイテッド 組み換え受容体を発現しているドナーバッチ細胞を産生するための方法
KR20240018454A (ko) 2021-05-06 2024-02-13 주노 테라퓨틱스 게엠베하 T 세포의 자극 및 형질도입 방법
WO2023017115A1 (en) 2021-08-11 2023-02-16 Iba Lifesciences Gmbh Fractionation of cells based on a marker protein
CN113908589B (zh) * 2021-10-08 2022-09-27 天津工业大学 一种表面印迹抗体的疏水电荷诱导模式膜层析介质及其制备方法
WO2023147510A1 (en) 2022-01-28 2023-08-03 Juno Therapeutics, Inc. Chromatography arrays and related methods and kits
EP4223381A1 (en) * 2022-02-02 2023-08-09 Sartorius BIA Separations d.o.o. Method of purifying or removing a target component from full plasma
WO2023213969A1 (en) 2022-05-05 2023-11-09 Juno Therapeutics Gmbh Viral-binding protein and related reagents, articles, and methods of use
WO2023230581A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Methods of manufacturing t cell therapies
WO2024100604A1 (en) 2022-11-09 2024-05-16 Juno Therapeutics Gmbh Methods for manufacturing engineered immune cells
WO2024124132A1 (en) 2022-12-09 2024-06-13 Juno Therapeutics, Inc. Machine learning methods for predicting cell phenotype using holographic imaging

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2624470B2 (ja) 1984-10-02 1997-06-25 バイオジェン インコーポレイテッド ストレプトアビジン様ポリペプチドの製造
US4851341A (en) 1986-12-19 1989-07-25 Immunex Corporation Immunoaffinity purification system
DE4237113B4 (de) 1992-11-03 2006-10-12 "Iba Gmbh" Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
AU5132096A (en) 1995-01-30 1996-08-21 Terrapin Technologies, Inc. Glubodies - multiplicities of proteins capable of binding a variety of small molecules
WO1996024606A1 (en) 1995-02-09 1996-08-15 University Of Washington Modified-affinity streptavidin
CA2222035A1 (en) * 1995-04-11 1997-03-27 Trustees Of Boston University Streptavidin mutants
DE19641876B4 (de) 1996-10-10 2011-09-29 Iba Gmbh Streptavidinmuteine
US6368813B1 (en) 1997-03-14 2002-04-09 The Trustees Of Boston University Multiflavor streptavidin
US5985658A (en) 1997-11-14 1999-11-16 Health Research Incorporated Calmodulin-based cell separation technique
DE19932688B4 (de) 1999-07-13 2009-10-08 Scil Proteins Gmbh Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
EP1227321A1 (en) 2000-12-28 2002-07-31 Institut für Bioanalytik GmbH Reversible MHC multimer staining for functional purification of antigen-specific T cells
DE10113776B4 (de) 2001-03-21 2012-08-09 "Iba Gmbh" Isoliertes streptavidinbindendes, kompetitiv eluierbares Peptid, dieses umfassendes Fusionspeptid, dafür codierende Nukleinsäure, Expressionsvektor, Verfahren zur Herstellung eines rekombinanten Fusionsproteins und Verfahren zum Nachweis und/oder zur Gewinnung des Fusionsproteins
WO2003029462A1 (en) 2001-09-27 2003-04-10 Pieris Proteolab Ag Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
DE50312184D1 (de) * 2002-03-01 2010-01-14 Volker A Erdmann Streptavidin-bindungspeptid
US7754155B2 (en) * 2002-03-15 2010-07-13 Ross Amelia A Devices and methods for isolating target cells
FR2841905B1 (fr) 2002-07-05 2004-09-03 Centre Nat Rech Scient Fragments fab mutants de l'anticorps anti-cd4 chimere 13b8.2 et leurs applications
CA2546066A1 (en) * 2003-11-20 2005-06-02 Biosensor Applications Sweden Ab (Publ) Mixture of at least two different antibodies specific for predetermined antigens and use of the mixture
EP1766400B1 (en) * 2004-06-03 2009-04-15 Meso Scale Technologies, LLC Methods for conducting whole blood assays
GB0422431D0 (en) * 2004-10-08 2004-11-10 Affitech As Method
JP5255841B2 (ja) * 2004-10-15 2013-08-07 ジェネンコー・インターナショナル・インク 競合示差スクリーニング
US20060252087A1 (en) * 2005-01-18 2006-11-09 Biocept, Inc. Recovery of rare cells using a microchannel apparatus with patterned posts
US7855057B2 (en) * 2006-03-23 2010-12-21 Millipore Corporation Protein splice variant/isoform discrimination and quantitative measurements thereof
CN105699662A (zh) * 2006-11-02 2016-06-22 协和梅迪克斯株式会社 免疫测定待测组分的方法
AU2007353319A1 (en) * 2006-11-15 2008-11-20 Invitrogen Dynal As Methods for reversibly binding a biotin compound to a support
CN101226118B (zh) * 2007-01-19 2010-06-16 中国医学科学院肿瘤研究所 一种兼容免疫荧光分析的细胞化学染色方法及其用途
JP4962215B2 (ja) 2007-08-28 2012-06-27 パナソニック株式会社 墨出し器の精度確認装置及び墨出し器の精度確認方法
KR20220008944A (ko) * 2008-01-18 2022-01-21 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 체액 내에서 질병 또는 병태의 시그너쳐의 검출 방법
EP3363893B1 (en) 2008-01-29 2021-06-30 Fred Hutchinson Cancer Research Center Identification of cd8+ t cells that are cd161hi and/or il18ralphahi and have rapid drug efflux capacity
EP2363501A1 (en) * 2010-03-02 2011-09-07 Universitätsklinikum Hamburg-Eppendorf Method for isolating target cells
WO2012017081A1 (en) * 2010-08-06 2012-02-09 Ludwig-Maximilians-Universität München Identification of t cell target antigens
EP2734538B2 (en) 2011-07-18 2024-07-03 IBA Lifesciences GmbH Method of reversibly staining a target cell
AU2013224027B2 (en) 2012-02-23 2019-01-24 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
RS62471B1 (sr) 2014-04-16 2021-11-30 Juno Therapeutics Gmbh Metode, kompleti i uređaji za proširenje populacije ćelija
MA45488A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés, kits et appareil de culture de cellules
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
RU2761555C2 (ru) 2015-10-22 2021-12-09 Джуно Терапьютикс Гмбх Способы, наборы, средства и устройства для трансдукции

Also Published As

Publication number Publication date
AU2019200178B2 (en) 2021-09-09
JP2023016981A (ja) 2023-02-02
HK1202335A1 (zh) 2015-09-25
CN106940268B (zh) 2021-09-21
US20190234844A1 (en) 2019-08-01
RU2746407C1 (ru) 2021-04-13
WO2013124474A3 (en) 2013-12-05
JP6857626B2 (ja) 2021-04-14
JP7192014B2 (ja) 2022-12-19
US20150024411A1 (en) 2015-01-22
EP2817625A2 (en) 2014-12-31
CN104254780A (zh) 2014-12-31
WO2013124474A2 (en) 2013-08-29
US20190226951A1 (en) 2019-07-25
CA2865033A1 (en) 2013-08-29
JP2015512621A (ja) 2015-04-30
JP6362543B2 (ja) 2018-07-25
JP2021090471A (ja) 2021-06-17
JP2018108103A (ja) 2018-07-12
AU2019200178A1 (en) 2019-01-31
SG11201404991YA (en) 2014-09-26
AU2021282451A1 (en) 2022-01-06
IN2014DN06475A (zh) 2015-06-12
CN104254780B (zh) 2017-04-12
AU2013224027B2 (en) 2019-01-24
CA2865033C (en) 2021-11-02
CN106940268A (zh) 2017-07-11
AU2013224027A1 (en) 2014-10-02
US10228312B2 (en) 2019-03-12

Similar Documents

Publication Publication Date Title
HK1202335A1 (zh) 細胞和其它複雜生物材料的色譜分離
HK1210494A1 (zh) 用於細胞培養的裝置和方法
HK1205195A1 (zh) 抗體及其使用方法
GB201013989D0 (en) Biological materials and methods of using the same
EP2892562A4 (en) ANTI-MCAM ANTIBODIES AND ASSOCIATED METHOD FOR USE
EP2912174A4 (en) METHOD AND MATERIALS FOR ISOLATING NUCLEIC ACID MATERIALS
IL238227A0 (en) Antibodies against c16orf54 and uses thereof
ZA201404675B (en) Anti-lrp5 antibodies and methods of use
EP2742123A4 (en) ISOLATION AND DETECTION OF CANCER CELLS
HK1211627A1 (zh) 試劑材料和有關的試驗元件
EP2938632A4 (en) ANTI-GRANULYSIN ANTIBODIES AND METHODS OF USE
EP2748337A4 (en) CELL SENSITIVITY ASSAY FOR CANCER AND METHODS OF PRODUCTION AND USE THEREOF
HK1209432A1 (zh) 抗鋸齒蛋白抗體及使用方法
SG11201502497RA (en) Sebocyte cell culturing and methods of use
SG11201503592TA (en) Case for containing biological samples and corresponding method of use
SG11201406771PA (en) Stem cell preparations and methods of use
GB201215352D0 (en) Improvements in and relating to the anaalysis of sample
AU2012900478A0 (en) Preservation of Biological Materials
GB201112000D0 (en) Biological materials and uses thereof
AU2012901799A0 (en) Thermo-Electrochemical Cell and Method of Use